%0 Journal Article %T Mushroom Ganoderma lucidum Prevents Colitis-Associated Carcinogenesis in Mice %A Daniel Sliva %A Jagadish Loganathan %A Jiahua Jiang %A Andrej Jedinak %A John G. Lamb %A Colin Terry %A Lee Ann Baldridge %A Jiri Adamec %A George E. Sandusky %A Shailesh Dudhgaonkar %J PLOS ONE %D 2012 %I Public Library of Science (PLoS) %R 10.1371/journal.pone.0047873 %X Epidemiological studies suggest that mushroom intake is inversely correlated with gastric, gastrointestinal and breast cancers. We have recently demonstrated anticancer and anti-inflammatory activity of triterpene extract isolated from mushroom Ganoderma lucidum (GLT). The aim of the present study was to evaluate whether GLT prevents colitis-associated carcinogenesis in mice. %U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0047873