%0 Journal Article
%T Sulfasalazine-induced DRESS syndrome (Drug Rash with Eosinophilia and Systemic Symptoms)
%A Aquino
%A Renata Telles Rudge de
%A Vergueiro
%A Carmen Silvia Vieitas
%A Magliari
%A Maria Elisa Ruffolo
%A Freitas
%A Thais Helena Proen£ża de
%J Sao Paulo Medical Journal
%D 2008
%I Scientific Electronic Library Online
%R 10.1590/S1516-31802008000400006
%X context: dress syndrome (drug rash with eosinophilia and systemic symptoms) is a type of drug reaction commonly mistaken for a viral infection. it must be recognized promptly due to its high morbidity and 10% mortality rate. few cases of dress syndrome induced by sulfasalazine have been reported in the literature. case report: the case of a 47-year-old white brazilian woman who developed dress syndrome eight weeks after starting a course of sulfasalazine for treatment of seronegative arthritis is reported. she presented a skin rash, fever, hepatitis, lymphadenopathy, eosinophilia and atypical lymphocytes. the causative drug was discontinued immediately, but she only improved after treatment with prednisone.
%K drug eruptions
%K sulfasalazine
%K hypersensitivity
%K eosinophilia
%K sulfonamides.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S1516-31802008000400006&lng=en&nrm=iso&tlng=en