%0 Journal Article %T £¿-hCG en fluidos vaginales como marcador de rotura prematura de membranas %A Bufalino Fianchino %A Gesualdo %A Aponte Cubill¨¢n %A Ayar¨ª %A Carrillo Garc¨ªa %A Hecna %A Bello %A Freddy %A Fabrega Trueba %A Ramona %A Adri¨¢n Pineda %A Carlos %J Revista de Obstetricia y Ginecolog¨ªa de Venezuela %D 2003 %I Sociedad de Obstetricia y Ginecolog¨ªa de Venezuela %X objective: to determine the utility of the high concentrations of the £¿-chorionic gonadotropin hormone in vaginal fluids in the diagnosis of premature rupture of membranes. methods: prospective and comparative study in 120 healthy pregnant women divided into 2 groups, with and without premature rupture of membranes. the concentrations of this hormone in vaginal fluids were determined. setting: delivery room. "maternidad concepcion palacios", caracas. results: the concentrations of £¿-chorionic gonadotropin hormone in vaginal fluids higher than 17.10 mui/ml are related with premature rupture of membranes, with a sensibility of 98.33 %, specificity of 93.33 %, positive predictive value of 93.65 % and negative predictive value of 98.54 %. conclusions: the high concentrations of £¿-chorionic gonadotropin hormone in vaginal fluids constitute a reliable method for the diagnosis of premature rupture of membranes. %K £¿-chorionic gonadotropin hormone %K premature rupture of membranes %K vaginal fluids. %U http://www.scielo.org.ve/scielo.php?script=sci_abstract&pid=S0048-77322003000400001&lng=en&nrm=iso&tlng=en