%0 Journal Article
%T Heterogeneidad biol¨®gica y cl¨ªnica de la leucemia linfoide aguda pedi¨¢trica de fenotipo T
%A Mars¨¢n Su¨¢rez
%A Vianed
%A Cos Padr¨®n
%A Yanelkys
%A Fuentes de Armas
%A Lillian Teresa
%A Socarr¨¢s Ferrer
%A Bertha Beatriz
%A S¨¢nchez Segura
%A Miriam
%A N¨²£¿ez Quintana
%A Aram¨ªs
%A Svarch Guerchicoff
%A Eva
%A Lam D¨ªaz
%A Rosa
%A del Valle P¨¦re
%A L¨¢zaro O
%A Mac¨ªas Abraham
%A Consuelo
%J Revista Cubana de Hematolog£¿-a, Inmunolog£¿-a y Hemoterapia
%D 2005
%I Editorial Ciencias M¨¦dicas
%X the biological and clinical characteristics of 31 children with phenotype t acute lymphoid leukemia (t-all) were studied in a period of 14 years. the cellular immunophenotyping was performed by the immunocytochemical (umiciq) and alkaline phosphatase anti-alkaline phosphatase (apaap) methods. it was observed a higher incidence (38.5 %) in the age group 2-5. the white male children were the most affected. 61.3 % of the patients showed leukocytes < 20x109/l at the onset of the disease. the mean figure of hemoglobin was 8.8x109/l. 71 % presented lymphadenopathies and splenomegalia. mediastinal mass, hepatomegalia and hemorrhages were found in 32.2 %, 83.9 % and 16.1 %, respectively. 25.8 % had infiltration of the central nervous system. the immunological classification revealed a predominance of the late t-all variety (45.2 %) over the early (29 %) and the cortical (25.8 %). 2 (6,4 %) mi+ t-all were diagnosed. these results proved that the t-all of the child is a clinical and biologically heterogeneous disease
%K acute lymphoid leukemia
%K phenotype t.
%U http://scielo.sld.cu/scielo.php?script=sci_abstract&pid=S0864-02892005000100006&lng=en&nrm=iso&tlng=en