%0 Journal Article %T Detecci車n de Helicobacter pylori y caracterizaci車n del la regi車n -31 del gen de la Interleucina 1-ˋ humana en pacientes de una poblaci車n colombiana con enfermedades gastroduodenales %A Montealegre Ortiz %A Mar赤a Camila %A Jaramillo Henao %A Carlos %A Boh車rquez Lozano %A Mabel Elena %A Montealegre Lynett %A Gustavo %A Delgado %A Mar赤a del Pilar %J Revista Colombiana de Gastroenterologia %D 2008 %I Asociaci車n Colombiana de Gastroenterolog赤a %X the aim of this study was to investigate the presence of helicobacter pylori and interleukin 1-汕 genotyping (il-1b -31), to determine the relationship between one polymorphism in the -31 region of interleukin 1-汕 gene and the severity of the clinical manifestations. gastric biopsies from 71 patients were submitted to histopathological examination and genotyped by molecular methods (pcr y pcr-rflp). the results indicated that 97.2% of the patients have alterations in the gastric mucosa, the presence of h. pylori was demonstrated in 44 patients and tt, ct and cc genotypes were detected in 12.7%, 60.6% and 26.8%, respectively. il-1b genotypes were not associated with the severity of gastric mucosal damage in the studied population. %K human interleukin 1-ˋ %K genotyping %K pcr-rflp %K gastroduodenal diseases %K colombia. %U http://www.scielo.org.co/scielo.php?script=sci_abstract&pid=S0120-99572008000100005&lng=en&nrm=iso&tlng=en