%0 Journal Article %T Genetic variability of a population of Aedes aegypti from Paran¨¢, Brazil, using the mitochondrial ND4 gene %A Twerdochlib %A Adriana L. %A Bonna %A Ana C. Dalla %A Leite %A Selene S. %A Chitolina %A Rodrigo F. %A Westphal %A Betina %A Navarro-Silva %A Mario A. %J Revista Brasileira de Entomologia %D 2012 %I Sociedade Brasileira De Entomologia %R 10.1590/S0085-56262012005000030 %X genetic variability of a population of aedes aegypti from paran¨¢, brazil, using the mitochondrial nd4 gene. to analyze the genetic variability of populations of aedes aegypti, 156 samples were collected from 10 municipalities in the state of paran¨¢, brazil. a 311 base pairs (bp) region of the nadh dehydrogenase subunit 4 (nd4) mitochondrial gene was examined. an analysis of this fragment identified eight distinct haplotypes. the mean genetic diversity was high (h = 0.702; p = 0.01556). amova analysis indicated that most of the variation (67%) occurred within populations and the fst value (0.32996) was highly significant. fst values were significant in most comparisons among cities. the isolation by distance was not significant (r = -0.1216 and p = 0, 7550), indicating that genetic distance is not related to geographic distance. neighbor-joining analysis showed two genetically distinct groups within paran¨¢. the dna polymorphism and amova data indicate a decreased gene flow in populations from paran¨¢, which can result in increased vectorial competence. %K aedes aegypti %K genetic variability %K mitochondrial dna %K genetic population %K state of paran¨¢. %U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0085-56262012000200013&lng=en&nrm=iso&tlng=en