Objectives: To study the clinicopathological pattern of gastric cancer in-cluding the location of the tumor in the stomach and to compare our results with other studies. Design: Prospective study of patients confirmed with gastric malignancy during the period from July 2016 to July 2017. Setting: Specialized center of gastrointestinal and liver diseases in Ibb city, Yemen. Subjects: All patients with histopathological confirmation of gastric malig-nancy. Results: During the study period, we had 69 patients with gastric cancer; among them 48 were males and 21 were females, with male: Female ratio is 2.2:1. The age ranged between 35 years and 90 years and the mean age was 65.87 ± 12.79 years. Most of the patients presented with epigastric pain (87%), weight loss (72.5%), pallor (65.2%), dysphagia (47.8%), vomiting (42%), palpable epigastric mass (20.3%) and hematemesis/melena (18.8%). The cardiofundal location was encountered in 33 cases (47.8% ), 22 (45.8%) males and 11 (52.4%) females, the corpus location in 24 cases (26%), 20 (41.7%) males and 4 (19%) females, the antral location in 8 cases (11.6%), 4 (8.3%) males and 4 (19%) females and the whole stomach in 4 cases (5.8%), 2 (4.2%) males and 2 (9.5%) females. Adenocarcinoma constituted about 94.2%, of which the intestinal type was 87.5% and the diffuse type was 12.5%. The non-epithelial tumor was encounter 4.3%, of which 2.9% were lymphoma and 1.4% were GIST. Conclusion: In our studied patients, proximally located gastric cancer was the most common in both sexes.
Cite this paper
Kassim, A. , Al-Qubaty, M. , Al-Yousofy, F. , Alathwary, R. and Ameen, S. (2018). Clinicopathological Pattern of Gastric Cancer of Yemeni Patients in Ibb Governorate. Open Access Library Journal, 5, e4415. doi: http://dx.doi.org/10.4236/oalib.1104415.
Brain, R.W., Nicki, R.C., Stuart, H.R. and Ian, D.P. (2014) Davidson’s Principle and Practice of Medicine. 22nd Edition, Churchill Livingstone, Edinburgh London New York Oxford Philadelphia, Chapter 22, 877.
Dan, L.L., Dennis, L.K., Jameson, J.L., Anthony, S.F., Stephen, L.H. and Joseph, L. (2012) Harrison’s Principle of Internal Medicine. 18th Edition, Vol. 2, John Kretschmer, New York, 765-767.
Joseph, B.M., Mabula, D.M., Mheta, K., Phillipo, L.C., Fabian, M. and Peter, F.R. (2012) Gastric Cancer at a University Teaching Hospital in Northwestern Tanzania: A Retrospective Review of 232 Cases. World Journal of Surgical Oncology, 10, 2.
Parkin, D.M., Bray, F., Ferlay, J. and Pisani, P. (2005) Global Cancer Statistics, 2002. CA: A Cancer Journal for Clinicians, 55, 74-108. https://doi.org/10.3322/canjclin.55.2.74
Anderson, W.F., Camargo, M.C., Fraumeni, J.F., Correa, P., Rosenberg, P.S. and Rabkin, C.S. (2010) Age-Specific Trends in Incidence of Noncardia Gastric Cancer in US Adults. JAMA, 303, 1-5.
Al-Makdad, A.M., Al-Dholaee, M.H., Thabet, A.A.K., Al-Haimi, M.A., Balfaqih, O.S. and Al-Hadad, A.M. (2013) Prevalence of Helicobacter Pylori Infection in Yemeni Patients. Yemeni Journal for Medical Sciences, 7, 37.
David, A.S., Abdul-Basit, A., Mohammad, I., Abdul-Rauf, K. and Abdul-Naser, A.B. (1995) Gastric Cancer: A Clinicopathological Analysis of 54 Cases Seen at Asir central Hospital. Saudi Medical Journal, 16, 308-310.
Nassima, C., Khan, A.R., Romana, M. and Saud, L. (2007) Histopathology of Gastric Cancer in Kashmir—A Five Year Retrospective Analysis. JK SCIENCE, 9, 23.
Miomir, P., Aleksandar, K., Nebojsa, D., Vuka, K., Zoran, R., Milan, R., Nikola, I. and Ivan, P. (2004) The Importance of Primary Gastric Cancer Location in 5-Year Survival Rate. Arch Oncology, 12, 51.
Mofleh, I.A. (1992) Gastric Cancer in Upper Gastrointestinal Endoscopy Population: Prevalence and Clinicopathological Characteristics. Annals of Saudi Medicine, 12, 548-551.
Haitham Al-Mahrouqi, L.P. and Sharples, K. (2011) Incidence of Stomach Cancer in Oman and the Other Gulf Cooperation Council Countries. Oman Medical Journal, 26, 258-262.
Selcukbiricik, F., Buyukunal, E., Tural, D., Ozguroglu, M., Demirelli, F. and Serdengecti, S. (2013) Clinicopathological Features and Outcomes of Patients with Gastric Cancer: A Single-Center Experience. World Journal of Gastroenterology, 19, 2154-2161.
Albasri, A.M., Elsawaf, Z.M., Hussainy, A.S. and Alhujaily, A.S. (2017) Clinicopathological Profile of Gastric Cancers in Al-Madinah, Saudi Arabia. The Journal of the Pakistan Medical Association, 67, 834-838.
Balint, E.E., Falkay, G. and Balint, G.A. (2009) Khat: A Controversial Plant. Wiener Klinische Wochenschrift, 121, 604-614. https://doi.org/10.1007/s00508-009-1259-7
Borrmann, R. (1926) Geschwulste des Magens und Duodenum. In: Henke, F. and Lubarch, O., Eds., Handbuch der spezielen pathologischen anatomie und histology, Springer Verlag, Berlin, 35.
Felix, B., Elfriede, B., Uta, D., Arnulf, H.H. and Stefan, M. (2014) Pathohistological Classification Systems in Gastric Cancer: Diagnostic Relevance and Prognostic Value. World Journal of Gastroenterology, 20, 5680-5681.