Background: H. pylori infection is strongly related with chronic gastritis of the antrum of the
stomach, which causes impairment in gastric acid and pepsin secretion, and is
thus linked to malabsorption of food-vitamin B12. H. pylori can cause an
individual to have a vitamin B12 deficiency. It is also a known contributor to
gastritis ulcers and it can prevent the stomach from being able to absorb the
vitamin B12 you consume and leads to a deficiency of vitamin B12. The purpose
of this study is to determine the frequency of vitamin B12 deficiency in Helicobacter
pylori infected patients.
Methods: All
patients aged 17 - 65 years, of either gender
were evaluated for urine vitamin B12 level by human vitamin B12 ElSA kit. The
data were analyzed
in statistical software (SPSS) and the P-value = 0.05 was considered as statistically
significant. Results: Of one hundred subjects, 65
(65%) were males, while 35 (35%) were
females. 31 (36.0%) H. pylori infected patients had normal
vitamin B12 level and 55 (64%) were Vitamin B12 deficiency in 86 (86%). H.
pylori infected patients with a significant difference (P value <
0.05). Conclusions:
Vitamin B12 deficiency is more prevalent in Helicobacter pylori infected
patients.
Cite this paper
Kadhim, G. , Shikh, M. , Omar, H. and Ismail, A. (2018). Vitamin B12 Deficiency in Helicobacter pylori Infected Patients. Open Access Library Journal, 5, e4172. doi: http://dx.doi.org/10.4236/oalib.1104172.
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