Abrikossoff’s
tumor or granular cell tumor is a rare soft and usually benign tissue neoplasm
of neural origin. It occurs usually in the neck region or in the head. About
16% occur in the vulva. Some malignant cases have been reported in literature.
Granular cell tumor was described first by Abrikossoff in 1926. The
histogenesis of granular cell tumors is unknown. The clinical diagnosis of
vulvar granular cell tumor is difficult. It may be mistaken for Bartholin gland
cyst, lipoma or vulvar carcinoma when ulcerated. Histology is the mainstay of
the positive diagnosis. Imagery is not essential for the diagnosis of Abrikossoff’s
tumor. It is asked when the neoplasm is giant, or when there is a local recurrence
or potential metastasis. Surgery is the gold standard treatment of
Abrikossoff’s tumor. It consists of local excision with wide margins. Prognosis
of granular cell tumor is usually good. Authors report a 25-year-old woman
presented with an ulcerate tumor on the labium majus. The objective of this paper is to review the
clinical and therapeutic aspects of Abrikossoff’s tumor located in the vulva from case report and literature review.
Cite this paper
Laajili, H. , Zaidi, S. , Bannour, I. , Zoukar, O. , Massoudi, K. , Korbi, A. and Faleh, R. (2017). Abrikossoff’s Tumor of the Vulva, Case Report and Literature Review. Open Access Library Journal, 4, e3705. doi: http://dx.doi.org/10.4236/oalib.1103705.
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