Background: Recently the
data has been increasing on the
association between Helicobacter pylori infection and thrombocytopenia characterization specifically in developing
countries. Objective: This study was aimed to evaluate platelet count and
platelet indices in Helicobacter pylori infected patients. Materials and Method: This is a case
control study conducted in the Faculty of Medical Laboratory at Alneelain University, Khartoum-Sudan. A total of
240 participants was enrolled in this study; 120 of them are a patient group
known diagnosed with H. pylori infection; 60 (50%) male, 60 (50%) female; their
mean age is (30.22 ± 1.92) years designed as patient
group. And another 120 designated as normal, healthy control group; 60 (50%)
male and 60 (50%) female. Blood samples were collected from each subject in ethylene diamine
tetra acetic acid (EDTA). The platelet count and platelet Indices were done by using full automated
hematological Analyzer Sysmex (KXN-21)
Japan. The
data were analysed by using (SPSS) version 20. Result: Platelet count and platelet distribution
width (PDW)
were shown
statistically significantly lower; on the other hand the MPV
was found higher in patients with H. pylori infection compared with normal
healthy control group with p value 0.03, 0.01 and 0.00 respectively. Conclusion:
Mild thrombocytopenia with elevated in mean platelet volume (MPV) and low on
the platelet distribution width (PDW) were found in patients with H.pylori infection.
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