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Tuberculosis Treatment Outcomes and Determinants among Patients Treated in Hospitals in Imo State, Nigeria

DOI: 10.4236/oalib.1102754, PP. 1-17

Subject Areas: Epidemiology

Keywords: Tuberculosis, Treatment Outcome, Patients, Hospital, Imo State

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Abstract

Introduction: Tuberculosis is a highly feared disease, known for centuries to affect, debilitate, impoverish large sections of the population and continues to ravage the world and especially the developing world. TB is curable and its effective treatment has shown a significant effect on the control of the disease. Methodology: This was a retrospective hospital based study carried out on records of 1025 TB cases, treated from 2009-2012 cohorts. A structured proforma was used to collect information from the TB registers, individual cards and folder records of the patients. Data were analyzed using a software package, EPI INFO version 7.1.3. Frequencies tables and summary indices were generated and chi-square was used to test association between variables where appropriate. P-value of ≤0.05 was considered significant. Results: Most of the cases reviewed had pulmonary tuberculosis. 96.7% and majority (86.3%) of them had sputum smear positive results at diagnosis. Majority, 79.7% of the patients were new cases and the treatment outcome showed a total success rate of 81.4%, (cured, 46.3% and completed treatment, 35.1%), default, (9.8%), died (6.5%) and failed treatment (1.5%). Factors found to significantly affect treatment outcome in this study were; age, gender, educational status, religion, living with someone, treatment regimen, HIV status of patients and type of patient at presentation/diagnostic criteria, p < 0.05. Conclusion: The success rate recorded in this study was below the set target by WHO, thus there was a need to put in place appropriate measures to improve the outcome of TB treatment in Imo State, Nigeria.

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Duru, C. B. , Uwakwe, K. A. , Nnebue, C. C. , Diwe, K. C. , Merenu, I. A. , Emerole, C. O. , Iwu, C. A. and Duru, C. A. (2016). Tuberculosis Treatment Outcomes and Determinants among Patients Treated in Hospitals in Imo State, Nigeria. Open Access Library Journal, 3, e2754. doi: http://dx.doi.org/10.4236/oalib.1102754.

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