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Rare Case of Kleine-Levin Syndrome with Mega Cisterna Magna

DOI: 10.4236/oalib.1102550, PP. 1-6

Subject Areas: Neurology

Keywords: Kleine-Levin Syndrome (KLS), Mega Cisterna Magna, Na Valporate

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Abstract

Kleine-Levin syndrome (KLS) is an uncommon syndrome characterized by recurrent episodes of hypersomnia, behavioural and/or cognitive disturbances, abnormal eating and hypersexual behaviour. The diagnosis is clinical and requires a high index of suspicion and exclusion of other neurological conditions and sleep disorders. We report a case of 15-year-old male who had recurrent episodes of hypersomnia with hyperphagia, hypersexuality, disinhibition and cognitive dysfunction. His brain CT scan shows Mega cistern magna and EEG during the episode shows sharp and spike wave in both frontal and temporal lobes with secondary generalization. The patient became symptom-free after receiving Na Valporate.

Cite this paper

Alqubaty, A. S. , Mujlli, H. M. and Haroon, Z. T. (2016). Rare Case of Kleine-Levin Syndrome with Mega Cisterna Magna. Open Access Library Journal, 3, e2550. doi: http://dx.doi.org/10.4236/oalib.1102550.

References

[1]  Ramdurg, S. (2010) Kleine-Levin Syndrome: Etiology, Diagnosis, and Treatment. Annals of Indian Academy of Neurology, 13, 241-246.
http://dx.doi.org/10.4103/0972-2327.74185
[2]  Arnulf, I., Lin, L., Gadoth, N., File, J., Lecendreux, M., Franco, P., Zeitzer, J., Lo, B., Faraco, J.H. and Mignot, E. (2008) Kleine-Levin Syndrome: A Systematic Study of 108 Patients. Annals of Neurology, 63, 482-493.
http://dx.doi.org/10.1002/ana.21333
[3]  Turan, T., Besirli, A., Asdemir, A., Ozsoy, S. and Esel, E. (2010) Manic Episode Associated with Mega Cisterna Magna. Psychiatry Investigation, 7, 305-307.
http://dx.doi.org/10.4306/pi.2010.7.4.305
[4]  Haba-Rubio, J., Prior, J.O., Guedj, E., et al. (2012) Kleine-Levin Syndrome: Functional Imaging Correlates of Hypersomnia and Behavioral Symptoms. Neurology, 79, 1927.
http://dx.doi.org/10.1212/WNL.0b013e318271f85a
[5]  Landtblom, A.M., Dige, N., Schwerdt, K., Safstrom, P. and Granerus, G. (2002) A Case of Kleine-Levin Syndrome Examined with SPECT and Neuropsychological Testing. Acta Neurologica Scandinavica, 105, 318-321.
http://dx.doi.org/10.1034/j.1600-0404.2002.1c162.x
[6]  Huang, Y.S., Guilleminault, C., Kao, P.F. and Liu, F.Y. (2005) SPECT Findings in the Kleine-Levin Syndrome. Sleep, 28, 955-960.
[7]  Abhijit, D., Meena, G., Yogesh, P., Yogesh, P. and Amit, B. (2014) Kleine-Levin Syndrome—A Syndrome of Periodic HyperSomnia: A Case Report. Indian Journal of Applied Research, 4.
[8]  Elian, M. (1968) Periodic Hypersomnia. Electroencephalography and Clinical Neurophysiology, 24, 192-193.
[9]  Huang, Y.S., Guilleminault, C., Kao, P.F. and Liu, F.Y. (2005) SPECT Findings in the Kleine-Levine Syndrome. Sleep, 28, 955-960.
[10]  Hong, S.B., Joo, E.Y., Tae, W.S., Lee, J., Han, S.J. and Lee, H.W. (2006) Episodic Diencephalic Hypoperfusion in Kleine-Levin Syndrome. Sleep, 29, 1091-1093.
[11]  Schmahmann, J.D. (1991) An Emerging Concept. The Cerebellar Contribution to Higher Function. Archives of Neurology, 48, 1178-1187.
http://dx.doi.org/10.1001/archneur.1991.00530230086029
[12]  Brambilla, P., Harenski, K., Nicoletti, M., Mallinger, A.G., Frank, E., Kupfer, D.J., et al. (2001) MRI Study of Posterior Fossa Structures and Brain Ventricles in Bipolar Patients. Journal of Psychiatric Research, 35, 313-322.
http://dx.doi.org/10.1016/S0022-3956(01)00036-X
[13]  Ichimiya, T., Okubo, Y., Suhara, T. and Sudo, Y. (2001) Reduced Volume of the Cerebellar Vermis in Neuroleptic-Naive Schizophrenia. Biological Psychiatry, 49, 20-27.
http://dx.doi.org/10.1016/S0006-3223(00)01081-7
[14]  Mills, N.P., Delbello, M.P., Adler, C.M. and Strakowski, S.M. (2005) MRI Analysis of Cerebellar Vermal Abnormalities in Bipolar Disorder. The American Journal of Psychiatry, 162, 1530-1532.
http://dx.doi.org/10.1176/appi.ajp.162.8.1530
[15]  Schoch, B., Kaiser, O., Groetschel, H., Dimitrova, A., Hein-Kropp, C., et al. (2005) Behavioral and Affective Changes in Children and Adolescents with Chronic Cerebellar Lesions. Neuroscience Letters, 381, 102-107.
http://dx.doi.org/10.1016/j.neulet.2005.02.011

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