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Applications of Nanotechnology in Reconstructive Surgery

DOI: 10.4236/oalib.1102455, PP. 1-7

Subject Areas: Surgery & Surgical Specialties, Synthetic Biology, Biotechnology, Composite Material, Biological Engineering, Molecular Biology, Cell Biology, Biological Materials, Bioengineering

Keywords: Poly(L-Lactide-Co-Glycolide) (PLGA), Poly(ε-Carpolactone) (PCL), Hydroxyapatite/Polyamide (n-HA/PA), Silicon Nanoribbon (SiNR)

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Abstract

The objective of this review was to critically present and evaluate recent investigations into nanotechnology and it’s applications in reconstructive surgery. In addition, this review aims to looks at a plethora of applications with nanotechnology in the subject area of reconstructive surgery. The Medline and PubMed databases were searched for clinical trial and case report publications dealing with reconstructive surgeries involving nanotechnology. Reports that were identified addressed different areas of reconstructive surgery and outlined a clear methodology for their studies. Eight publications show that the use of nanotechnology in reconstructive surgery is promising yet still in its early stages and that extensive research needs to be carried out if the expectation of this advancing technology is to overtake current surgical procedures. However, it is clear that there will be a continued interest and progression in this subject field as nanotechnology science is unveiled.

Cite this paper

Varghese, T. (2016). Applications of Nanotechnology in Reconstructive Surgery. Open Access Library Journal, 3, e2455. doi: http://dx.doi.org/10.4236/oalib.1102455.

References

[1]  Loizidou, M. and Seifalian, A.M. (2010) Nanotechnology and Its Applications in Surgery. British Journal of Surgery, 97, 463-465.
http://dx.doi.org/10.1002/bjs.7074
[2]  Heath, C.A. and Rutkowski, G.E. (1998) The Development of Bioartifical Nerve Grafts for Peripheral Regeneration. Trends in Biotechnology, 16, 163-168.
http://dx.doi.org/10.1016/S0167-7799(97)01165-7
[3]  Wang, S., Wan, A.C., Xu, X., Gao, S., Mao, H.Q., Leong, K.W. and Yu, H. (2001) A New Nerve Guide Conduit Material Composed of a Biodegradable Poly(Phosphoester). Biomaterials, 22, 1157-1169.
http://dx.doi.org/10.1016/S0142-9612(00)00356-2
[4]  Panseri, S. and Cunha, C. (2008) Electrospun Micro- and Nanofiber Tubes for Functional Nervous Regeneration in Sciatic Nerve Transections. BMC Biotechnology, 8, 39.
http://dx.doi.org/10.1186/1472-6750-8-39
[5]  Bryan, D.J., Holway, A.H., Wang, K.K., Silva, A.E., Trantolo, D.J., Wise, D.S. and Umerhayes, I.C. (2000) Influence of glial growth factor and Schwann cells in a Bioresorbable Guidance Channel on Peripheral Nerve Regeneration. Tissue Engineering, 6, 129-138.
[6]  Siekierka, J.J. and Sigal, N.H. (1992) FK-506 and Cyclosporine A: Immunosuppressive Mechanism of Action and Beyond. Current Opinion in Immunology, 4, 548-552.
http://dx.doi.org/10.1016/0952-7915(92)90024-9
[7]  Steiner, P., Dawson, T.M. and Fotuhi, C. (1991) The Immunosuppressant FK506 Enhance Phosphorylation of GAP-43: Implication for a Role In Modulation of Growth Cone Function and Neurotransmitter Release. Society for Neuroscience Abstracts, 18, 603-608.
[8]  Li, T., Zhang, X.J., Li, J. and Kan, Q.C. (2014) Effect of FK506 Nanospheres on Regeneration of Allogeneic Nerve after Transplant. Asian Pacific Journal of Tropical Medicine, 2014, 478-482.
http://dx.doi.org/10.1016/S1995-7645(14)60078-X
[9]  Morris, C.L., Barber, R.F. and Day, R. (2000) Orofacial Prosthesis Design and Fabrication Using Stereolithography. Australian Dental Journal, 45, 250-253.
http://dx.doi.org/10.1111/j.1834-7819.2000.tb00259.x
[10]  Wang, H., Li, Y., Zuo, Y., Li, J., Ma, S. and Cheng, L. (2007) Biocompatibility and Osteogenesis of Biomimetic Nano- Hydroyapatite/Polyamide Composite Scaffolds for Bone Tissue Engineering. Biomaterials, 28, 3338-3348.
http://dx.doi.org/10.1016/j.biomaterials.2007.04.014
[11]  Li, J., Hsu, Y., Luo, E., Khadha, A. and Hu, J. (2001) Computer-Aided Design and Manufacturing and Rapifprotoypednanoscale Hydroxyapatite/Polyamide (n-HA/PA) Construction for Condylar Defect Caused by Mandibular Angle Ostectomy. Aesthetic Plastic Surgery, 35, 636-640.
[12]  Ghaati, S., Unger, R.E., Webber, M.J., et al. (2011) Scaffold Vascularisation in Vivo Driven by Primary Human Osteoblasts in Concert with Hot Inflammatory Cells. Biomaterials, 32, 8150-8160.
http://dx.doi.org/10.1016/j.biomaterials.2011.07.041
[13]  Barker, A.D., Bowers, B.T., Hughley, B., Chance, E.W., Klembczyk, K.J., Brayman, K.L., Park, S.S. and Botchwey, E.A. (2013) Multilayer Cell-Seeded Polymer Nanofiber Constructs for Soft-Tissue Reconstruction. JAMA Otolaryngology-Head and Neck Surgery, 139, 914-922.
http://dx.doi.org/10.1001/jamaoto.2013.4119
[14]  Kim, J., Lee, M. and Shim, H.J. (2014) Stretchable Silicon Nanoribbon Electronics for Skin Prosthesis. Nature Communications, 5, 5754.
http://dx.doi.org/10.1038/ncomms6747
[15]  Takabayashi, Y., Ishihara, M., Sumi, Y., Takikawa, M., Nakamura, S. and Kiyosawa, T. (2015) Platelet-Rich Plasma- Containing Fragmin-Protamine Micro-Nanoparticles Promote Epithelialisation and Angiogenesis in Split-Thickness Skin Graft Donor Sites. Journal of Surgical Research, 193, 483-491.
http://dx.doi.org/10.1016/j.jss.2014.08.011
[16]  Kon, E., Filardo, G., Venieri, G., Perdisa, F. and Marcacci, M. (2014) Tibial Plateau Lesions. Surface Reconstruction with a Biomimetic Osteochondral Scaffold: Results at 2 Years of Follow-Up. Injury, 45S, S121-S125.
[17]  Choi, J.S., Leong, K.W. and Yo, S.H. (2008) In Vivo Wound Healing of Diabetic Ulcers Using Electrospun Nanofibers Immobilized with Human Epidermal Growth Factor (EGF). Biomaterials, 29, 587-596.
http://dx.doi.org/10.1016/j.biomaterials.2007.10.012
[18]  Oryan, A., Moshiri, A. and Parizi-Meimandi, A. (2014) In Vitro Characterisation of a Novel Tissue Engineered Based Hybridized Nano and Micro Structured Collagen Implant and Its in Vivo Role on Tenoinduction, Tenoconduction, Tenogenesis and Tenointergration. Journal of Materials Science: Materials in Medicine, 25, 873-897.
http://dx.doi.org/10.1007/s10856-013-5110-3

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