Stomach is considered the “gold standard” as an esophageal substitute
after esophagectomy. Reflux disease is considered an unavoidable consequence of
esophageal resection followed gastric interposition. Reflux esophagitis shows a
progression from inflammation to erosions and to the development of columnar
lined metaplasia. With the use of a gastric interposition, the most popular
option to reconstruct the esophagus resected for malignant or benign conditions
creates an in vivo model of reflux disease. Gastric interposition is far from ideal as an esophageal substitute. Reflux
esophagitis and new columnar lined metaplasia should be seen as a new complication
of subtotal esophagectomy.
Cite this paper
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