This study was
performed to investigate the epidemiology of adenovirus related acute lower respiratory
tract infection in children through a large sample collection. Totally 76,518
patients admitted to Children’s Hospital Affiliated to Zhejiang University School
of Medicine were investigated from July 2006 to June 2012. Nasopharyngeal
aspirates were collected and examined by immunofluorescence assay to confirm
viral etiology. There were 479 patients positive for adenovirus (6.3‰) and pneumonia accounted for most of these
patients. The median age of adenovirus infected was 16 months and peaked at the
second six-month of life. Winter, spring and summer had the similar positive
rate, while autumn had the lowest occurrence rate. The detection rates of adenovirus
on each spring from 2007 to 2012 were 18.01‰,
5.73‰,
11.85‰,
6.35‰,
11.77‰ and 2.66‰, respectively, which indicated a prevalence
appearing once every two years.
Cite this paper
Zheng, Q. , Lu, M. and Li, W. (2015). The Epidemiology of Adenovirus Associated Lower Respiratory Tract Infection in Hospitalized Children in Hangzhou City, China. Open Access Library Journal, 2, e777. doi: http://dx.doi.org/10.4236/oalib.1100777.
Larranaga, C., Kajon, A.
and Avendano, L.F. (2000) Hospital-Acquired Adenovirus 7 h Infantile
Respiratory Infection in Chile. Pediatric
Infectious Disease Journal, 19, 527-531. http://dx.doi.org/10.1097/00006454-200006000-00007
Louie, J.K.,
Kajon, A.E. and Holodniy, M. (2008) Severe Pneumonia Due to Adenovirus
Serotype 14: A New Respiratory Threat. Clinical Infectious Diseases, 46, 421-425. http://dx.doi.org/10.1086/525261
Khamis, F.A.,
Al-Kobaisi, M.F. and Al-Areimi, W.S. (2012) Epidemiology of Respiratory Virus
Infections among Infants and Young Children Admitted to Hospital in Oman. Journal of Medical Virology, 84, 1323-1329. http://dx.doi.org/10.1002/jmv.23330
Endo, R., Ishiguro, N.
and Kikuta, H. (2007) Seroepidemiology of Human Bocavirus in
Hokkaido Prefecture, Japan. Journal of
Clinical Microbiology, 45, 3218-3223. http://dx.doi.org/10.1128/JCM.02140-06
Henquell, C., Boeuf, B. and Mirand, A.
(2009) Fatal Adenovirus Infection in a Neonate and Transmission to Health- Care
Workers. Journal of Clinical Virology,
45, 345-348. http://dx.doi.org/10.1016/j.jcv.2009.04.019
Weigl, J.A.,
Puppe, W. and Meyer, C.U.
(2005) RSV-Prevention in Children Guided by a Web-Based Early Warning System. Klinische Padiatrie, 217, 47-52. http://dx.doi.org/10.1055/s-2004-836246
Weigl, J.A., Puppe, W. and Meyer, C.U.
(2007) Ten Years’ Experience with Year-Round Active Surveillance of up to 19
Respiratory Pathogens in Children. European
Journal of Pediatrics, 166, 957-966. http://dx.doi.org/10.1007/s00431-007-0496-x
Shaman, J. and Kohn, M.
(2009) Absolute Humidity Modulates Influenza Survival, Transmission, and Seasonality. Proceedings of
the National Academy of Sciences of the United States of America, 106, 3243-3248. http://dx.doi.org/10.1073/pnas.0806852106
Welliver, R.
(2009) The Relationship of Meteorological Conditions to the Epidemic Activity
of Respiratory Syncytial Virus. Paediatric
Respiratory Reviews, 10, 6-8. http://dx.doi.org/10.1016/S1526-0542(09)70004-1
du Prel, J.-B., Puppe, W. and Grondahl, B. (2009) Are Meteorological Parameters Associated
with Acute Respiratory Tract Infections? Clinical
Infectious Diseases, 49, 861-868. http://dx.doi.org/10.1086/605435