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Search Results: 1 - 10 of 16695 matches for " ovary cancer "
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An Up-to-Date Understanding of the “Krukenberg Tumor” Mechanism  [PDF]
Bikash Shah, Wenhao Tang, Shammi Karn
Advances in Reproductive Sciences (ARSci) , 2016, DOI: 10.4236/arsci.2016.42005
Abstract: Krukenbergtumor is a metastatic ovarian tumor with its primary site being the gastrointestinal tract. The pathogenesis of Krukenberg tumor formation is still in its hypothetical stage though the current understanding suggests lymphatic, hematogenous and transcoelomic route as the 3 major route of metastasis. There is a lack of description in the literature related to the pathway of metastasis. Here, we intend to search the available literature and provide a thorough review, which may be helpful to the readers to understand the issue of mechanism of Krukenberg tumor metastasis more clearly.
Liver Metastases from Gynecological Cancers: Time to Resection?  [PDF]
Jose M. Ramia, Roberto De La Plaza, Jose Qui?ones, Pilar Veguillas, Farah Adel, Jorge García-Parre?o
Surgical Science (SS) , 2012, DOI: 10.4236/ss.2012.33024
Abstract: Aim: To perform an update of liver resection as treatment of liver metastases of gynecological cancers, as well as an update on these metastases. Bibliographical search: PubMed Search 1990-2011 in English language. Authors reviewed only relevant articles. Results: No more than 20 relevant articles have been published on this topic, including case reports. We performed a classical review of the information published in the literature. Conclusions: Liver Metastases from Gynecological cancers, not peritoneal implants in the liver, usually appear in patients with disseminated disease, so it is uncommon to perform a liver resection. In some patients with limited extrahepatic disease or only liver disease, liver resection is a safe alternative and improves the oncological results. We try to emphasize which patients may benefit from liver resection and the importance of tailoring medical decisions.
Cáncer de ovario heredo familiar: A propósito de un caso
Saint Surin,Anne; Alvarez,Jorge; Ibarra,Omaira; Digianmarco,Doris; Filippini,Joel;
Revista Venezolana de Oncología , 2007,
Abstract: objective: the syndrome of family cancer is mainly an entity of cancer colorrectal associated to endometrial cancer; however it can be associated also to ovary cancer and other adenocarcinomas, having a pattern of inheritance dominant autosomic with variable penetration that can arrive to 50 % in a family of first grade. methods: the case is presented of patient of 45 years who enters to the service of gynecology of the hospital vargas of caracas to present symptomatic uterine fibromatosis and a tumor right para uterine of probable ovarian origin. results: she is carried out gynecological laparotomy, tumor exeresis with biopsy perioperatoria that report cancer ovary epithelial is carried out complete oncological protocol of ovary. the definitive biopsy concludes that is a carcinoma of ovary type cells clear pattern classic mesonefroide in 50 % and patron tubule papillary and of cells oxifílicas, classified how stadium ib. conclusions: in view of the type histological we decides chemotherapy, after the five cycle tumor is diagnosed in half rectum whose biopsy report moderate adenocarcinoma evidences poorly differentiated t1n0m0 stadium i. it completes chemotherapy 6 cycles and it is taken to surgical where she is carried out low previous resection, previous proctectomía and colorrectoanastomosis. the definitive biopsy reports adenocarcinoma mucinoso with cells in stamp ring moderated to poorly differentiate that it infiltrates the whole wall including the serous t3n0m0 stadium ib, it is being concluded the case like how a syndrome of ovary inherits family.
Bone metastasis from ovarian cancer
Tiwari Anu,Kumar Narendra,Bajpai Ranjeet,Lal Punita
Journal of Cancer Research and Therapeutics , 2007,
Abstract: We report a case of epithelial ovarian cancer, which presented with lumbar vertebral metastasis soon after treatment, as a part of distant spread. This patient was then treated by palliative radiotherapy and put on second line chemotherapy i.e., Topotecan. She responded to treatment well.
Tumores das células da granulosa dos ovários: estudo de 24 casos
Bezerra, Artur Lício Rocha;Lorenzato, Felipe Rinalo Barbosa;
Revista Brasileira de Ginecologia e Obstetrícia , 2004, DOI: 10.1590/S0100-72032004000800003
Abstract: objective: to evaluate staging, surgical procedures and outcome of ovarian granulosa cell tumors (gct), with emphasis in the possibility of conservative surgery (unilateral ooforectomy). methods: this is a retrospective cohort study in which 24 patients treated with gct during the period of january 1994 to january 2004 were included. variables of interest such as patient's age, symptoms, tumor size on physical examination, staging, treatment modalities (types of surgery and of adjuvant chemotherapy and/or radiotherapy) and prognosis have been analyzed. the chi-square test was used to check the association between variables, and the level of significance was set at p < 0.05, always describing the two-tailed fisher exact test. results: the patients' age varied from 30 to 82 (mean 51.7) years old. the most frequently referred symptom was pelvic pain (n = 10; 41.7%). fourteen patients (58.3%) presented clinical stage (cs) ic, 5 (20.8%) cs iiic and 5 (20.8%) cs ia. more advanced clinical stages were significantly associated with palpable pelvic masses (p < 0.04). endometrial hyperplasias were found in 3 (25%) of the 12 hysterectomy specimens. the follow-up period varied from 2 to 114 (mean 42.5) months. among the 16 (66.7%) surviving and disease-free patients, 4 had cs ia (25%), 11 cs ib (68.8%) and 1 cs ic (6.3%), whereas all patients who died had cs iiic (p = 0.0008). all 6 patients (25%) that underwent conservative surgery were alive and without recurrence. conclusion: although gct usually present low aggressiveness, the clinical staging continues to be the main prognostic factor and hence it determines the option for conservative surgery and the use of adjuvant therapy.
Cistoadenocarcioma mucinoso de ovário e esclerose sistêmica
Araújo, Maíta Poli de;Barros, Alfredo Carlos Sim?es Dornelas de;Calil, Marcelo Alvarenga;Carvalho, Cláudio Roberto Bianco de;Cepeda, Lourdes Alves;Ferraz, Fausto Motta;Pinto, Rodrigo Ambar;Peterson, Thais Villela;Trevisani, Virginia Fernandes Mo?a;
Revista Brasileira de Reumatologia , 2004, DOI: 10.1590/S0482-50042004000100021
Abstract: ovarian cancer is the third cause of death among malignant neoplasia in women, and the mucinous cystadenocarcinoma is a malignant neoplasia of the ovarian epithelium, which may achieve great dimensions. some studies suggest an increased risk of neoplasia in patients with systemic sclerosis (ssc), but the association with ovarian neoplasia, specially the mucinous subtype, is rare. the authors describe a case of ovarian mucinous cystoadenocarcinoma in a 52 year-old caucasian woman who had the diagnosis of ssc 6 years ago, previously treated with cyclophosphamide and d-penicillamine, who sought for a medical service complaining of pain and increase of abdominal volume during the last three months. at the physical examination, she presented sclerodermic facies, upper limbs with decreased elasticity and bitibial graft in the lower limbs; in the abdomen, a hardened mass extending to the suprapubic region up to the epigastric was observed. exploratory laparotomy was performed and a cystic mass was found in the right ovary, weighing 3,300 grams. a surgical removal of the tumor with total hysterectomy and bilateral oophorectomy was then performed. histological examination confirmed the diagnosis of mucinous cystadenocarcinoma without capsule invasion.
Ovarian tumors in childhood and adolescence: Histopathological evaluation of 44 cases
Sevgiye KA?AR ?ZKARA,Deniz F?L?NTE
Türk Patoloji Dergisi , 2007,
Abstract: Ovarian tumors of childhood and adolescence constitute the most frequent and special group of gynaecologic tumors due to clinical and histopathological peculiarities and age specific therapeutic implications related to physically, hormonally and immunologically immature host. Pathologic features of ovarian tumors of children and adolescents diagnosed in our department in ten-year period, constitute the perspective of this report. Macroscopical, microscopical, immunohistochemical, and cytopathological features of ovarian tumors under 21-years-of age, and diagnosed in 1997-2006 are re-evaluated.Fourty-two cases (9.7%) belong to the young patients among 391 primary ovarian tumors diagnosed in tenyears. Germ-cell tumors were the most frequent (54.8%) while epithelial tumors were 38.1% and sexcord- stromal tumors was 7.1%. Malignancy rate was 28.6% among all subtypes while epithelial malignancy were 4.8%. Malignancy under 16 years was 31.3% while it was 26.9% in adolescence. Epithelial tumors in childhood was 18.8% while it was 50% over 16 years; the difference was significant (p=0.043). In our series, 60.9% of germ cell tumors were mature cystic teratomas. Malignancy rate within this group was 39.1%. There were four pure dysgerminomas, three mixed germ cell tumors and two immature teratomas within the malignant germ cell tumors. The mean tumor diameter was 92.1 mm. in benign tumors while it was 172.9 mm. in malignant tumors, and the difference was significant (p=0.001). Most of the solid tumors were malignant (p=0.002).As the malignancy potential among the young was considerably high, a detailed clinical and pathological evaluation is mandatory for abdominopelvic masses.
Secondary ovarian tumors: Evaluation of 44 cases
Sevgiye KA?AR ?ZKARA,Deniz F?L?NTE
Türk Patoloji Dergisi , 2007,
Abstract: Secondary ovarian tumors compose 3-8% of all, and 10-30% of malignant ovarian tumors. Histopathological features of SOT diagnosed in our department in 10-year period are discussed. Macroscopical, microscopical, immunohistochemical and cytopathological features of secondary ovarian tumors diagnosed between 1997- 2006 were re-evaluated. Additional histochemical and immunohistochemical studies were applied to find the primaries. Data was statistically evaluated. Totally, 44 secondary ovarian tumors had been diagnosed within this period. The mean age of the patients was 52.9 years; the mean tumor diameter was 103.7 mm.The primary was gastrointestinal system in 50% of the cases. Ten of them (22.7%) were metastases of signet ring cell carcinoma of stomach (Kruckenberg tumor) while 9 cases (20.5%) were from colorectal and three (6.8%) were from appendiceal adenocarcinomas. 27.3% of our cases were originated from genital tract. Synchronous endometrioid adenocarcinomas of corpus uteri and ovary were seen in six cases (13.6%). Ovarian involvement of serous carcinomas of corpus uteri was seen in five (11.4%) cases. Ovarian metastases of breast carcinoma in four cases (9.1%) were seen while the ovarian involvement of adrenal cortical and tubal carcinomas was observed in one case, each. The primary was peritoneal surface in five (11.4%) of the cases. Tumors were bilateral in 65.9% of the cases, and there was statistically significant correlation between the bilaterality rate of the tumors and the primary (p=0.015).The more precise diagnosis of secondary ovarian tumors could be reached by evaluation of clinical, surgical, macroscopical, microscopical, cytopathological and immunohistochemical findings together.
Registro de cáncer ginecológico Clínica San Pedro Claver, Bogotá, Colombia 2003
González,Mario A;
Revista Colombiana de Obstetricia y Ginecología , 2005,
Abstract: objective: reviewing new cases of gynaeco-logical cancer attending clínica san pedro claver, bogotá, colombia during 2003. material and methods: the clinic?s oncolo-gical gynaecology committee facilitated compiling data as all new patients benefiting from this service are interviewed by it; a search was made during clinical meetings, in consultants? offices, amongst hospitalised patients, of operating room schedules and pathological reports to ensure including all new cases. the data so collected was recorded in an excel file; epiinfo software was then used for analysing it. results: there were 158 cases of gynaecological cancer, cervical cancer being encountered most frequently (46%). this neoplasm was divided into exocervix (59 cases) and endocervix (16 cases) categories; the cancerous stage found most often in both was ib. surgery was most often employed as treatment for this type of cancer. endometrial cancer was found in 46 women. stage i (50%), endometroid cancer (55%) and sur-gery (55%) were the stages, histology and treatment most often found, respectively. 34 patients were found to have ovarian cancer, presenting the same ratio of stages i-ii as late stage iii-iv; serous histology was most frequently encountered (52.3%). a combination of surgery and chemotherapy were most often employed for treating this disease. conclusions: clínica san pedro claver?s insti-tutional records led to establishing the distribution of different gynaecological tumours being evaluated there, establishing related personal and clinical cha-racteristics and the types of therapy being received. cervical cancer was found to be the gynaecological cancer appearing most frequently during 2003 in clínica san pedro claver. this type of cancer can be detected by pap smear screening (cervical-vagi-nal cytology), meaning that screening/prevention programmes for this disease should be given high priority.
Neoplasias associadas à síndrome dos ovários policísticos
Spritzer, Poli Mara;Morsch, Débora Martinho;Wiltgen, Denusa;
Arquivos Brasileiros de Endocrinologia & Metabologia , 2005, DOI: 10.1590/S0004-27302005000500022
Abstract: polycystic ovary syndrome (pcos) is the most common endocrine disease in women on reproductive age. pcos is characterized by the presence of anovulation, infertility and hyperandrogenism and is associated with obesity and insulin resistance. a major risk for neoplasms of the reproductive tract, like endometrial, breast and ovary cancer seems to be related to pcos. while several studies have shown an increased risk for endometrial hyperplasia and cancer in pcos patients, the variability of the selection criteria for pcos has been recognized as a potential bias for these data. pcos women also present clinical characteristics that are related to risk factors for breast cancer and some epidemiological evidences have been described on this issue. however, until now, a clear association between the presence of pcos and breast carcinoma has yet not been found. finally, high local steroid and growth factor concentrations are considered risk factors for ovary carcinoma, and are frequently observed in pcos women. in turn, few studies have addressed the possibility of a link between pcos and ovarian cancer and the results are conflicting but suggest that this association is unlikely.
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