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Search Results: 1 - 10 of 100 matches for " loyds.swenson "
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迈克耳孙
loyds.swenson,jr.
物理 , 1982,
Abstract: ?艾伯特·亚伯拉罕·迈克耳孙(albertabrahammichelson)1852年12月19日生于普鲁士的斯特列罗(strelno,现属波兰),1931年5月9日死于(美)加利福尼亚州帕萨迪纳(pa-sadena),专长物理学、光学和计量学。实验物理学中的精密测量是迈克耳孙终生所热爱的工作.1907年他成为第一位在一门科学中荣获诺贝尔奖金的美国公民.这是“由于他的精密光学仪器以及用这些仪器?...
On cyclic CAT(0) domains of discontinuity
Eric Swenson
Mathematics , 2010,
Abstract: Let $X$ be a CAT(0) space, and $G$ a discrete cyclic group of isometries of $X$. We investigate the domain of discontinuity for the action of $G$ on the boundary $\partial X$.
Phylogenetic Beta Diversity Metrics, Trait Evolution and Inferring the Functional Beta Diversity of Communities
Nathan G. Swenson
PLOS ONE , 2011, DOI: 10.1371/journal.pone.0021264
Abstract: The beta diversity of communities along gradients has fascinated ecologists for decades. Traditionally such studies have focused on the species composition of communities, but researchers are becoming increasingly interested in analyzing the phylogenetic composition in the hope of achieving mechanistic insights into community structure. To date many metrics of phylogenetic beta diversity have been published, but few empirical studies have been published. Further inferences made from such phylogenetic studies critically rely on the pattern of trait evolution. The present work provides a study of the phylogenetic dissimilarity of 96 tree communities in India. The work compares and contrasts eight metrics of phylogenetic dissimilarity, considers the role of phylogenetic signal in trait data and shows that environmental distance rather than spatial distance is the best correlate of phylogenetic dissimilarity in the study system.
Phylogenetic Resolution and Quantifying the Phylogenetic Diversity and Dispersion of Communities
Nathan G. Swenson
PLOS ONE , 2009, DOI: 10.1371/journal.pone.0004390
Abstract: Conservation biologists and community ecologists have increasingly begun to quantify the phylogenetic diversity and phylogenetic dispersion in species assemblages. In some instances, the phylogenetic trees used for such analyses are fully bifurcating, but in many cases the phylogenies being used contain unresolved nodes (i.e. polytomies). The lack of phylogenetic resolution in such studies, while certainly not preferred, is likely to continue particularly for those analyzing diverse communities and datasets with hundreds to thousands of taxa. Thus it is imperative that we quantify potential biases and losses of statistical power in studies that use phylogenetic trees that are not completely resolved. The present study is designed to meet both of these goals by quantifying the phylogenetic diversity and dispersion of simulated communities using resolved and gradually ‘unresolved’ phylogenies. The results show that: (i) measures of community phylogenetic diversity and dispersion are generally more sensitive to loss of resolution basally in the phylogeny and less sensitive to loss of resolution terminally; and (ii) the loss of phylogenetic resolution generally causes false negative results rather than false positives.
Stem cell therapeutics: potential in the treatment of inflammatory bowel disease
ES Swenson, ND Theise
Clinical and Experimental Gastroenterology , 2010, DOI: http://dx.doi.org/10.2147/CEG.S6836
Abstract: em cell therapeutics: potential in the treatment of inflammatory bowel disease Review (5433) Total Article Views Authors: ES Swenson, ND Theise Published Date January 2010 Volume 2010:3 Pages 1 - 10 DOI: http://dx.doi.org/10.2147/CEG.S6836 ES Swenson1, ND Theise2 1Department of Internal Medicine, Section of Digestive Diseases, Yale University School of Medicine, New Haven, CT, USA; 2Departments of Pathology and Medicine (Division of Digestive Diseases), Beth Israel Medical Center – Albert Einstein College of Medicine, New York, NY, USA Abstract: Stem cell therapies may be valuable in treatment of inflammatory bowel disease (IBD). Here we focus on two very different types of stem cells – hematopoietic stem cells and mesenchymal stem cells. Myeloablation and hematopoietic stem cell transplantation alter host immune response by reconstituting the recipient’s blood cell lines with donor cells. Autologous hematopoietic reconstitution may “reboot” mucosal immunity to a normal baseline state, but does not alter any underlying genetic predisposition to IBD. In contrast, allogeneic hematopoietic transplantation reconstitutes all blood lineages from a tissue-matched donor who presumably does not have a genetic predisposition to IBD. Compared with autologous hematopoietic transplantation, allogeneic hematopoietic transplantation carries a much greater risk of complications, including graft-versus-host disease. Mesenchymal stem cells can give rise to cartilage, bone and fat in vitro, but do not reconstitute hematopoiesis after transplantation. Systemically infused mesenchymal stem cells appear to favorably downregulate host immune responses through poorly understood mechanisms. In addition, mesenchymal stem cells may be applied topically to help close fistulas associated with Crohn’s disease. For all of these stem cell therapy applications for IBD, only cases and small series have been reported. Larger clinical trials are planned or ongoing.
SHOCK AND LAW: FIN 48 REPORT CARD, IFRS, AND BEYOND
Namryoung Lee,Charles Swenson
International Journal of Economics and Finance , 2010, DOI: 10.5539/ijef.v2n3p222
Abstract: The accounting for income taxes has, and will continue to, undergo significant changes. FASB Interpretation (FIN) 48 significantly revised the financial accounting for income taxes in 2007. In our sample, 87% of firms were immediately affected in terms of a restatement of beginning 2007 retained earnings. After enactment, discretionary accruals significantly decreased as firms apparently did not find other methods (other than through income tax accounts) to manage earnings. On the other hand, FIN 48 appears to have caused disruption in the reporting standards for income taxes, insofar as an increase in variability in effective tax rates across firms both the year before adoption, and the year of adoption. International Financial Reporting Standards (IFRS) will also make significant changes in 2012. We comment on the likely effects of IFRS adoption on US firms. Then, we examine the less volatile effects of IFRS on effective tax rates for European companies after 2004 as an example of what might happen in the US.
Gene-Specific Countermeasures against Ebola Virus Based on Antisense Phosphorodiamidate Morpholino Oligomers.
Warfield,Swenson,Olinger,Nichols
PLOS Pathogens , 2006,
Abstract: The filoviruses Marburg virus and Ebola virus (EBOV) quickly outpace host immune responses and cause hemorrhagic fever, resulting in case fatality rates as high as 90% in humans and nearly 100% in nonhuman primates. The development of an effective therapeutic for EBOV is a daunting public health challenge and is hampered by a paucity of knowledge regarding filovirus pathogenesis. This report describes a successful strategy for interfering with EBOV infection using antisense phosphorodiamidate morpholino oligomers (PMOs). A combination of EBOV-specific PMOs targeting sequences of viral mRNAs for the viral proteins (VPs) VP24, VP35, and RNA polymerase L protected rodents in both pre- and post-exposure therapeutic regimens. In a prophylactic proof-of-principal trial, the PMOs also protected 75% of rhesus macaques from lethal EBOV infection. The work described here may contribute to development of designer, "druggable" countermeasures for filoviruses and other microbial pathogens.
Earnings Management through Discretionary Expenditures in The U.S., Canada, and Asia
Namryoung Lee,Charles Swenson
International Business Research , 2011, DOI: 10.5539/ibr.v4n2p257
Abstract: There is a considerable literature on U.S. companies’ earnings management through discretionary accruals and real earnings management. We extend this literature to the international setting and include the effects of corporate tax on earnings management decisions. We find that US based models of earnings management work reasonably well in the Canadian setting, and except for the effects of taxes, in the Hong Kong, Japanese, Korean, and Taiwanese settings as well. We predict that firms’ tax status may have a countervailing effect on such management. Consistent with this prediction, we find that firms with larger potential tax savings are more likely to use real earnings management to accelerate discretionary expenditures. Since these discretionary deductions have income-reducing effects for financial reporting purposes, the results suggest that income taxes have a strong incentive effect. However, this tax effect occurs for only U.S. and Canadian firms; Hong Kong, Japanese, Korean, and Taiwanese firms’ discretionary accrual decisions appear to not be influenced by taxes. The results may have policy implications for other countries as well.
The Functional Ecology and Diversity of Tropical Tree Assemblages through Space and Time: From Local to Regional and from Traits to Transcriptomes
Nathan G. Swenson
ISRN Forestry , 2012, DOI: 10.5402/2012/743617
Abstract:
Preparing Teachers and Students for Narrative Learning
Sharon Sims,Melinda Swenson
The Journal of Scholarship of Teaching and Learning , 2001,
Abstract:
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