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Search Results: 1 - 10 of 56 matches for " keloid "
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Original Support of an after Piercing Lobular Keloid Scar: About a Case  [PDF]
Christiane Koudoukpo, Hugues Adégbidi, Spéro Raoul Hounkpatin, Félix Atadokpèdé, Julienne Téclessou, Fabrice Akpadjan, Bérénice Dégboé-Sounhin, Hubert G. Yédomon
Journal of Cosmetics, Dermatological Sciences and Applications (JCDSA) , 2013, DOI: 10.4236/jcdsa.2013.33A2007

Keloids are tissue repair formed by exuberant fibrosis appearing after a skin wound, burn, vaccination or post inflammatory (folliculitis or acne lesion). This condition causes standard aesthetic prejudice to those who are affected. Its management is difficult and its evolution meshes recurrences. We report here a case of giant keloid in the right ear lobe after a piercing and its support.

A Case for “Radiolysis” in Radiotherapy of Keloids  [PDF]
K. Malaker, H. Weatherburn, H. De Souza
International Journal of Medical Physics,Clinical Engineering and Radiation Oncology (IJMPCERO) , 2014, DOI: 10.4236/ijmpcero.2014.34029
Abstract: Successful treatment of keloids has eluded the medical community since their first description. Multitudes of therapeutic options are available, but none achieves satisfactory resolution of keloids. One major stumbling block is lack of understanding about their genesis. Assuming keloids are tumors, attempts have been made to treat this condition with standard radiotherapy, with dismal results. Keloidal masses are not an active biological entity. They are aggregations of cellular, hypovascular, hypoxic bundles of collagen, which are produced by atypical fibroblasts in the wounds and eventually cease production due to a hostile biological environment. Having no demonstrable inherent process of disposal of these collagen bundles, this excessive collagen tends to linger to form the bulk of keloids. The lesions eventually become symptomatic and aesthetically unacceptable, and therapeutic intervention is sought. Of all available treatments, such as post-resection radiotherapy, primary radiotherapy in selected cases and primary brachytherapy stand out above any other form of treatment. Be it brachytherapy or external beam treatment, one fundamental aspect of radiation action is the process of “radiolysis”, explaining why “radiobiological” approaches have been ineffective.
Debulking of Keloid Combined with Intralesional Injection of 5-Flurouracil and Triamcinolone versus Intralesional Injection of 5-Flurouracil and Triamcinolone  [PDF]
Khalifa E. Sharquie, Adil A. Noaimi, Mahmood R. Al-Karhi
Journal of Cosmetics, Dermatological Sciences and Applications (JCDSA) , 2014, DOI: 10.4236/jcdsa.2014.42013

Background: A wide range of therapies exist for keloids. But despite the multiple treatment modalities available, keloids still remain a significant challenge for both the clinician and the patient. Objective: To assess the effectiveness and safety of debulking of keloid with intralesional injection of 5-flurouracil and triamcinolone in comparison to intralesional injection of 5-flurouracil and triamcinolone alone. Patient and Methods: This single blinded comparative therapeutic outpatient based study was done at the Department of Dermatology, Baghdad Teaching Hospital during the period from February 2011 to February 2013. Twenty-three patients with 52 lesions were enrolled in the study and consisted of two groups: Group A (26 lesions): Treated by intralesional injection of combination of 5-flurouracil and triamcinolone acetonide and repeated every month; Group B (26 lesions): Debulking was carried out first and then injection of

Tratamento de queloide retroauricular: revis?o dos casos tratados no servi?o de otorrinolaringologia do HC/UFPR
Carvalho, Bettina;Ballin, Annelyse Cristine;Becker, Renata Vecentin;Ribeiro, Talita Beithum;Cavichiolo, Juliana Benthien;Ballin, Carlos Roberto;Mocellin, Marcos;
International Archives of Otorhinolaryngology , 2012, DOI: 10.7162/S1809-97772012000200007
Abstract: introduction: keloids are benign tumors arising from abnormal healing of the skin, and there are several procedures available for their treatment. objective: the objective of this study was to evaluate the outcomes of patients undergoing treatment of keloids after ear, nose, and throat (ent) surgeries at our service center. method: we conducted thorough, retrospective and prospective analysis of records of patients undergoing treatment of retroauricular keloids at our center. results: nine patients were evaluated, and 6 underwent resection and adjuvant beta-therapy, 2 underwent resection with local application of corticosteroids, and only 1 underwent resection without adjuvant therapy. there was no recurrence of keloids in patients that were treated with beta-therapy in the early postoperative period. one patient had relapsed despite corticosteroid administration and late beta-therapy. discussion: several techniques have been used for the treatment of retroauricular keloids, and beta-therapy is thought to yield the best results, followed by the use of intralesional corticosteroids. conclusion: treatment of retroauricular keloids remains a challenge. while new techniques are being developed, resection followed by early beta-therapy is still the best treatment option.
La cicatrización queloide
Cintr?n-Machón,Gustavo; Poveda-Xatruch,Juan;
Acta Médica Costarricense , 2008,
Abstract: the scarring process is the final and definitive repair of accidental, surgical and other types of wounds. this is a current complete and review of keloid scarring as a dermal - epidermis and neoplasic disease. the physiopathology of keloid scar formation is based on an abnormal collagen structure and alteration of healing phases. keloid scar is a cosmetic complication undesirable for all surgeons, but it is more important in plastic and reconstructive surgery. on this article we will talk about general aspects, physiopathology and treatment of keloid scars.
Dermatologia comparativa
Souza, Valdilene Loures de;Fraga, Juliana Cristina Silva;Gamonal, Aloísio;
Anais Brasileiros de Dermatologia , 2006, DOI: 10.1590/S0365-05962006000100014
Abstract: the authors show a case of keloid that is reminiscent of the bow-tie, a male piece of apparel.
Protocolo de tratamiento de cicatrices queloides en el pabellón auricular del Hospital General Dr. Manuel Gea González
Gutiérrez Gómez,C.; López Mendoza,F.J.; Lara Ontiveros,J.; Cervantes Díaz,J.P.; Márquez Gutiérrez,E.; Morales Naya,D.;
Cirugía Plástica Ibero-Latinoamericana , 2012, DOI: 10.4321/S0376-78922012000100006
Abstract: keloid scars are one of the most difficult pathologies to treat because its high rate of recurrence, from 100 % with single treatment to 50 % with combined therapy. the auricle is a frequent localization of keloids. we report our experience in the last 6 years with combined therapy in 51 patients and 64 auricles with keloid scars.: all scars were injected with triamcinolone or betamethasone 3 times with 4-6 weeks between each injection. four weeks after the last injection, the keloids were excised and skin closure was done without tension. in those patients with history of surgical excision, we added to the treatment colchicine, 1 mg daily, for 8 weeks with hepatic function test before and after the administration of colchicine. the keloid was unilateral in 74.5 % of the cases; 56.8 % females; the age of presentation was between 8 and 61 years old, with a media of 24 years old.the right auricle was affected in 65 % and the most frequently affected area was the lobule in 42 %.the etiology in 56 % of the cases were secondary to piercing. in 18.6 % of the cases the scar was resolved with the intralesional injection of triamcinolone or betametasone. from the 48 excisions performed, 12.5 % (6 keloid scars) presented recurrence, with a follow up of 8 months to 6 years.
Resultados do tratamento das cicatrizes queloideanas com cirurgia e imiquimode 5% creme: um estudo prospectivo
Umemura, álisson Yoshiharu;Orgaes, Flávio Augusto Flório Stillitano de;Canicoba, Newton José Borba;Dorsa, Patrícia Pinheiro;Guarizzo, Juliano;Gonella, Hamilton Aleardo;
Revista Brasileira de Cirurgia Plástica , 2011, DOI: 10.1590/S1983-51752011000100003
Abstract: introduction: the treatment of keloids represents a therapeutic challenge, with results often disappointing. more effective adjuvant therapies are needed to reduce high rates of relapse. this research is based on a combined modality with application of imiquimod 5% cream combined with surgery, having as objective the evaluation of treatment and recurrence of keloid scar. methods: this prospective study evaluated 14 patients at a total of 25 keloids, with a minimum follow up of 6 months. intralesional excision was performed and initiated the application of imiquimod 5% cream on the day of surgery and continued for two months. the evaluation of the scar was analyzed by an assessment scale (patient and an observer - ruler of service plastic surgery), signs of relapse and also the size of the scar in the pre-and postoperatively. results: after 6 months of follow up, patients showed an improvement of 72% and 88% in the ruler's analysis, with a recurrence rate of 8% and reduction of scar area (p = 0.0053). conclusion: the use of imiquimode 5% cream in the post surgery for resection of the keloid recurrence decreased significantly in their evaluation of 6 months.
What factors affect the quality of life of patients with keloids?
Furtado, Fabianne;Hochman, Bernardo;Ferrara, Soraia Francisco;Dini, Gal Moreira;Nunes, José Mário Camelo;Juliano, Yara;Ferreira, Lydia Masako;
Revista da Associa??o Médica Brasileira , 2009, DOI: 10.1590/S0104-42302009000600014
Abstract: objective: to evaluate factors that affect the quality of life (qol) of patients with keloids. methods: a study was conducted on 102 patients of both genders between 15 and 70 years old. during initial evaluation, clinical factors, such as keloid visibility, duration and evolution of the disease, previous treatments, types of treatments and recurrence were recorded. later, patients responded to the qualifibro questionnaire, which is specific for evaluation of the qol of patients with keloids and comprises the physical and psychological domains, and six visual numeric scales (vns), of which three are related to psychological factors (satisfaction with appearance, shame of the disease, and suffering experienced), and the other three are related to physical factors (pruritus, pain and movement restriction). results: patients with keloids on non-visible areas of the body (p<0.01) and more than 10 years of disease (p<0,049) reported higher scores on the physical domain of the qualifibro questionnaire, indicating increased severity compared with patients with keloids on visible areas of the body and disease duration of less than 10 years. there was a positive correlation between psychological (satisfaction with appearance, feelings of embarrassment about the disease and suffering experienced) and physical factors (pruritus, pain and movement restriction) evaluated using the vnss, and both domains of the qualifibro questionnaire. conclusion: results indicate that the physical domain of the qualifibro questionnaire was the most affected in patients with keloids on non-visible areas and in those with keloids for more than 10 years. psychological and physical factors associated with keloids as assessed with the vns affected both psychological and physical domains of qol.
Evaluación del efecto terapéutico del quelbén en pacientes con queloides
Negrín Varcárcel,Lourdes; Díaz de La Rocha Quevedo,Arturo; Bravo Hernández,Alicia; Rodríguez Lara,Laura; Hernández Rodríguez,Blanca J.; Mouris Oropesa,Norma;
Revista Cubana de Medicina General Integral , 2002,
Abstract: a study was conducted on 80 patients aged 15-25 years of any race and sex, who presented with keloids located in any part of their bodies. they were divided into two groups according to a random table designed for this end. one group was treated with a thermal mud-based product called quelbén and the other group was applied a 2% steroid cream for a period of 6 months. the clinical response to the treatment was evaluated on the basis of three parameters: size and thickness of lesion, consistency of lesion and accompanying subjective symptoms (rush, pain, hyperesthesia and tightness. the response to treatment with quelbén was positive either in clean patients (11) or responders to the treatment (21), which represented 91.3% in group a, a remarkably higher effectiveness of this treatment over the 2% steroidal cream used in group b (68.57%)
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