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Search Results: 1 - 4 of 4 matches for " Zucki "
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Correlation analysis of the long latency auditory evoked potential N2 and cognitive P3 with the level of lead poisoning in children
Alvarenga, Kátia de Freitas,Bernardez-Braga, Gabriela Rosito Alvarez,Zucki, Fernanda,Duarte, Josilene Luciene
International Archives of Otorhinolaryngology , 2013,
Abstract: Introduction: The effects of lead on children's health have been widely studied. Aim: To analyze the correlation between the long latency auditory evoked potential N2 and cognitive P3 with the level of lead poisoning in Brazilian children. Methods: This retrospective study evaluated 20 children ranging in age from 7 to 14 years at the time of audiological and electrophysiological evaluations. We performed periodic surveys of the lead concentration in the blood and basic audiological evaluations. Furthermore, we studied the auditory evoked potential long latency N2 and cognitive P3 by analyzing the absolute latency of the N2 and P3 potentials and the P3 amplitude recorded at Cz. At the time of audiological and electrophysiological evaluations, the average concentration of lead in the blood was less than 10 ug/dL. Results: In conventional audiologic evaluations, all children had hearing thresholds below 20 dBHL for the frequencies tested and normal tympanometry findings; the auditory evoked potential long latency N2 and cognitive P3 were present in 95% of children. No significant correlations were found between the blood lead concentration and latency (p = 0.821) or amplitude (p = 0.411) of the P3 potential. However, the latency of the N2 potential increased with the concentration of lead in the blood, with a significant correlation (p = 0.030). Conclusion: Among Brazilian children with low lead exposure, a significant correlation was found between blood lead levels and the average latency of the auditory evoked potential long latency N2; however, a significant correlation was not observed for the amplitude and latency of the cognitive potential P3.
Avalia o audiológica em crian as com baixo nível de exposi o cumulativa ao chumbo Audiological evaluation in children with low level of cumulative lead exposure
Kátia de Freitas Alvarenga,Daniela de Oliveira Manoel,Fernanda Zucki,Lilian Cássia Bórnia Jacob-Corteletti
Revista CEFAC , 2012, DOI: 10.1590/s1516-18462012005000096
Abstract: OBJETIVO: verificar a ocorrência de perda auditiva sensorioneural em crian as com baixo nível de exposi o cumulativa ao chumbo. MéTODO: 156 crian as intoxicadas por chumbo, 94 do sexo masculino e 62 do sexo feminino, na faixa etária entre 18 meses a 14 anos e 5 meses, foram submetidas a análise longitudinal do nível de Plumbemia em sangue, bem como audiometria tonal liminar e emiss es otoacústicas evocadas por estímulo transiente. RESULTADOS: a popula o pesquisada apresentou um valor médio de Plumbemia estimada de 12,2±5,7mg/dL (faixa entre 2,4-33mg/dL); todas as crian as apresentaram resposta normal na audiometria tonal liminar em 20 dBNA nas frequências testadas, 0,5; 1; 2 e 4 kHz, para ambas as orelhas; as emiss es otoacústicas evocadas por estímulo transiente estiveram presentes para todas as frequências bilateralmente, nas 79 crian as pesquisadas. CONCLUS O: n o foi constatada perda auditiva sensorioneural em crian as com histórico de baixo nível de exposi o cumulativa por chumbo, assim como n o foi encontrada les o de células ciliadas externas na cóclea, mesmo que subclínicas. PURPOSE: to verify the occurrence of sensorineural hearing loss in children with low level of cumulative lead exposure. METHOD: 156 lead-poisoned children, 94 males and 62 females, ranging in age from 18 months old to 14 years and 5 months old were subjected to analysis of longitudinal lead level in blood as well as pure tone audiometry and transient evoked otoacoustic emissions. RESULTS: the population studied had a mean estimated blood lead level of 12,2±5,7mg/dL (range between 2,4 and 33mg/dL); all children had a normal response in pure tone audiometry at 20 dBHL in the frequencies tested, 0.5, 1, 2 and 4 kHz, in both ears; the transient evoked otoacoustic emissions were presented for all frequencies bilaterally in 79 children surveyed. CONCLUSION: there has been no hearing loss in children with a history of low cumulative lead exposure, as there was no injury of cochlear outer hair cells, even if subclinical.
Correlation analysis of the long latency auditory evoked potential N2 and cognitive P3 with the level of lead poisoning in children
Alvarenga, Kátia de Freitas;Bernardez-Braga, Gabriela Rosito Alvarez;Zucki, Fernanda;Duarte, Josilene Luciene;Lopes, Andrea Cintra;Feniman, Mariza Ribeiro;
International Archives of Otorhinolaryngology , 2013, DOI: 10.7162/S1809-97772013000100007
Abstract: introduction: the effects of lead on children's health have been widely studied. aim: to analyze the correlation between the long latency auditory evoked potential n2 and cognitive p3 with the level of lead poisoning in brazilian children. methods: this retrospective study evaluated 20 children ranging in age from 7 to 14 years at the time of audiological and electrophysiological evaluations. we performed periodic surveys of the lead concentration in the blood and basic audiological evaluations. furthermore, we studied the auditory evoked potential long latency n2 and cognitive p3 by analyzing the absolute latency of the n2 and p3 potentials and the p3 amplitude recorded at cz. at the time of audiological and electrophysiological evaluations, the average concentration of lead in the blood was less than 10 ug/dl. results: in conventional audiologic evaluations, all children had hearing thresholds below 20 dbhl for the frequencies tested and normal tympanometry findings; the auditory evoked potential long latency n2 and cognitive p3 were present in 95% of children. no significant correlations were found between the blood lead concentration and latency (p = 0.821) or amplitude (p = 0.411) of the p3 potential. however, the latency of the n2 potential increased with the concentration of lead in the blood, with a significant correlation (p = 0.030). conclusion: among brazilian children with low lead exposure, a significant correlation was found between blood lead levels and the average latency of the auditory evoked potential long latency n2; however, a significant correlation was not observed for the amplitude and latency of the cognitive potential p3.
Hearing loss and acquired immune deficiency syndrome: systematic review
Araújo, Eliene da Silva;Zucki, Fernanda;Corteletti, Lilian Cássia Bórnia Jacob;Lopes, Andrea Cintra;Feniman, Mariza Ribeiro;Alvarenga, Kátia de Freitas;
Jornal da Sociedade Brasileira de Fonoaudiologia , 2012, DOI: 10.1590/S2179-64912012000200017
Abstract: purpose: to investigate the occurrence of hearing loss in individuals with hiv/aids and their characterization regarding type and degree. research strategy: it was conducted a systematic review of the literature found on the electronic databases pubmed, embase, adolec, ibecs, web of science, scopus, lilacs and scielo. selection criteria: the search strategy was directed by a specific question: "is hearing loss part of the framework of hiv/aids manifestations?", and the selection criteria of the studies involved coherence with the proposed theme, evidence levels 1, 2 or 3, and language (portuguese, english and spanish). data analysis: we found 698 studies. after an analysis of the title and abstract, 91 were selected for full reading. out of these, 38 met the proposed criteria and were included on the review. results: the studies reported presence of conductive, sensorineural, and mixed hearing loss, of variable degrees and audiometric configurations, in addition to tinnitus and vestibular disorders. the etiology can be attributed to opportunistic infections, ototoxic drugs or to the action of virus itself. the auditory evoked potentials have been used as markers of neurological alterations, even in patients with normal hearing. conclusion: hiv/aids patients may present hearing loss. thus, programs for prevention and treatment of aids must involve actions aimed at auditory health.
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