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Search Results: 1 - 10 of 78252 matches for " Zhiyi Chen "
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Sequence Analysis of the Full-length cDNA and Protein Structure Homology Modeling of FABP2 from Paralichthys Olivaceus
Xiaowu Chen,Zhiyi Shi
Bioinformatics and Biology Insights , 2009,
Analysis on Pollution Factors of Urban River  [PDF]
Zhiyi Lei
Journal of Geoscience and Environment Protection (GEP) , 2015, DOI: 10.4236/gep.2015.310002

Main pollutants of the urban scenic river in Nanjing City are studied in this paper. In the study area a total of 39 monitoring points are set in natural water, around pumping stations and near the tail water of sewage treatment plant. Through the monitoring of pollution sources of receiving conventional index, the pollution sources distribution and river pollution factors are detailed analyzed, as nutrient salts, heavy metals, and environmental endocrine disruptors. And sources of the pollution factors are analyzed by principal component analysis to get the main pollution factors in this channel.

Deposit Insurance System and the Commercial Bank Loan Loss Provisions  [PDF]
Zhiyi Wang
Modern Economy (ME) , 2019, DOI: 10.4236/me.2019.101012
The article mainly analyzes the deposit insurance system in our country promulgated after the provision for the impact of bank loan loss provisions. Empirical study found that the deposit insurance system in our country was promulgated in 2015, the bank’s loan loss provisions increased, among them, the big bank loan loss provisions significantly increased. After separating the manipulated loan loss provisions, we found that the manipulated loan loss provisions increased. Further study found that, following the promulgation of the deposit insurance system, managers in commercial bank weakened the motive of income smoothing, but the bank’s capital management behavior does not.

CHEN Wendong
, HE Zhiyi, YAN Yaqiong

- , 2018, DOI: 10.11887/j.cn.201801016
Abstract: 针对数字射频存储干扰机多通道宽带转发模式下的灵巧噪声干扰,提出了基于混沌调制信号、多谐波相位调制线性调频信号的正交分集抗干扰方法。混沌调制信号与多谐波相位调制线性调频信号具有“图钉”形模糊函数,除了具有良好的距离、多普勒分辨力,还对回波频率敏感,通过正交分集设计,能够更好地适应宽带转发灵巧噪声干扰。通过计算机仿真对新方法的抗干扰性能进行了分析和验证,结果表明:在多通道宽带转发灵巧噪声干扰环境下,新方法的抗干扰改善因子能够达到10 dB以上,抗干扰性能明显优于传统的频率捷变、斜率捷变方法。
In response to the smart noise jamming under multi-channel broadband digital radio frequency memory repeater jammer, an orthogonal decomposition method for anti-jamming was put forward on basis of chaotic modulation signals and multi harmonic phase modulation chirp signals. Both of these two signals have a ″thumbtack″ ambiguity function. They are not only of good resolving power in range and Doppler, but also of good sensitivity to echo frequency. By an orthogonal and diverse design, they can better adapt to the smart noise jamming under multi-channel broadband digital radio frequency memory repeater jammer. The result of analysis and validation on the anti-jamming performance of the new method through computer simulation shows that under smart noise jamming in multi-channel broadband digital radio frequency memory jammer, the electronic counter-countermeasures improvement factor of the new method can be more than 10 dB, which is much better than that of the traditional frequency and slope agility method.
Electroacupuncture pretreatment induces tolerance against focal cerebral ischemia through activation of canonical Notch pathway
Zhao Yu,Chen Xiyao,Ma Lei,Zuo Zhiyi
BMC Neuroscience , 2012, DOI: 10.1186/1471-2202-13-111
Abstract: Background Electroacupuncture (EA) pretreatment can induce the tolerance against focal cerebral ischemia. However, the underlying mechanisms have not been fully understood. Emerging evidences suggest that canonical Notch signaling may be involved in ischemic brain injury. In the present study, we tested the hypothesis that EA pretreatment-induced tolerance against focal cerebral ischemia is mediated by Notch signaling. Results EA pretreatment significantly enhanced Notch1, Notch4 and Jag1 gene transcriptions in the striatum, except Notch1 intracellular domain level, which could be increased evidently by ischemia. After ischemia and reperfusion, Hes1 mRNA and Notch1 intracellular domain level in ischemic striatum in EA pretreatment group were increased and reached the peak at 2 h and 24 h, respectively, which were both earlier than the peak achieved in control group. Intraventricular injection with the γ-secretase inhibitor MW167 attenuated the neuroprotective effect of EA pretreatment. Conclusions EA pretreatment induces the tolerance against focal cerebral ischemia through activation of canonical Notch pathway.
Distributed Middlebox Placement Based on Potential Game  [PDF]
Yongwen Li, Zhiyi Qu
Int'l J. of Communications, Network and System Sciences (IJCNS) , 2017, DOI: 10.4236/ijcns.2017.105B026
In this paper, we analyse the deployment of middlebox. For a given network information and policy requirements, an attempt is made to determine the optimal location of middlebox to achieve the best performance. In terms of the end-to-end delay as a performance optimization index, a distributed middlebox placement algorithm based on potential game is proposed. Through extensive simulations, it demonstrates that the proposed algorithm achieves the near-optimal solution, and the end-to-end delay decreases significantly.
Multiplex Immunoassays of Plant Viruses Based on Functionalized Upconversion Nanoparticles Coupled with Immunomagnetic Separation
Mingzhe Zhang,Wujian Chen,Xi Chen,Yongjiang Zhang,Xiaojia Lin,Zhiyi Wu,Mingfu Li
Journal of Nanomaterials , 2013, DOI: 10.1155/2013/317437
Abstract: A sensitive, specific and rapid method for the detection of three different kinds of plant viruses including tomato ringspot virus (ToRSV), bean pod mottle virus (BPMV) and arabis mosaic virus (ArMV) was demonstrated using novel upconversion nanoparticles (UCNPs) as a fluorescence marker coupled with immunomagnetic separation. Magnetic nanoparticles (MNPs, ~100?nm) were coated with different antibodies were employed to capture and enrich the target viruses. Then antibody-conjugated UCNPs as signal probes were added to form sandwich complexes. This was followed by a fluorescence measurement using a 980?nm laser. This method not only avoids the difficulty in simultaneous detection of multiple independent organic fluorphores that require distinct excitation wavelengths, and auto-fluorescence of biological samples due to the higher-energy excitation of QDs but also amplifies detection signal by UCNPs-tags together with easy separation of samples by magnetic forces, demonstrating the potential to be used for detecting virus in the field of environmental safety and other fields. 1. Introduction There is increasing interest in the development of nanotechnology for bioassay [1, 2]. In the past two decades, optical and magnetic materials have attracted much attention due to their importance in the fields of chemistry, biology, medical sciences, and biotechnology [3]. Fe3O4 nanoparticles are one of the most intensively studied magnetic nanoparticles and can be applied in a variety of areas, ranging from drug delivery [4] and biosensing [5], dynamic sealing [6], and cell labeling [7] to magnetic resonance imaging [8]. Moreover, MNPs are well suited for target capturing, enrichment, and isolation [9]. Accordingly, they can be used for isolating cells [10] and bacteria [11] and for removing environmental toxins such as heavy metals and chemical waste [12]. Research on fluorescent nanomaterials has also gained extensive attention in the past decade. Recently, colloidal semiconductor nanocrystals (quantum dots, QDs) have attracted many researchers due to their broad excitation, size-dependent photoluminescence with narrow emission bandwidth covering a wide spectral range, unusual photochemical stability, and relatively high photoluminescence quantum yield [13]. However, QDs excited by blue or short-wavelength UV radiation can induce autofluorescence of most biological tissues [14], which greatly decreases the sensitivity of detection. Moreover, the risk of systemic toxicity remains high, given their incorporation of heavy metals (e.g., Pb, Cd), precluding their
Effects of Thoracic Paravertebral Block on Postoperative Analgesia and Serum Level of Tumor Marker in Lung Cancer Patients Undergoing Video-assisted Thoracoscopic Surgery
Jiheng CHEN, Yunxiao ZHANG, Chuan HUANG, Keneng CHEN, Mengying FAN, Zhiyi FAN
- , 2015, DOI: : 10.3779/j.issn.1009-3419.2015.02.10
Abstract: Background and objective Perioperative management of pain associated with the prognosis of cancer patients. Optimization of perio-perative analgesia method, then reduce perioperative stress response, reduce opioiddosage, to reduce or even avoid systemic adverse reactions and elevated levels of tumor markers. Serum levels of tumor markers in patients with lung cancer are closely related to tumor growth. Clinical research reports on regional anesthesia effect on tumor markers for lung cancer are still very little in domesticliterature. The aim of this study is to evaluate the effects of thoracic paraverte-bral block on postoperative analgesia and serum level of tumor marker in lung cancer patients undergoing video-assisted thoracoscopic surgery. Methods Lung cancer patients undergoing video-assisted thoracoscopic surgery were randomly divided into 2 groups (n=20 in each group). The patients in group G were given only general anesthesia. The thoracic paravertebral blockade (PVB) was performed before general anesthesia in patients of group GP. The effect of PVB was judged by testing area of block. Patient controlled intravenous analgesia (PCIA) pump started before the end of surgery in 2 groups. Visual analogue scale (VAS) score was recorded after extubation 2 h (T1), 24 h (T2) and 48 h (T3) after surgery and the times of PCIA and the volume of analgesic drugs used were recorded during 48 h after surgery. The serum levels of carcino-embryonic antigen (CEA), carbohydrate antigen 199 (CA199), carbohydrate antigen 125 (CA125), neuron-specific enolase (NSE), cytokeratin 19 fragment (CYFRA21-1) and squamous cell carcinoma (SCC) in 40 lung cancer cases undergoing video-assisted thoracoscopic lobectomy were measured before operation and 24 h after operation. Results Forty American Society of Anesthesiologists (ASA) physical status I or II patients, aged 20 yr-70 yr, body mass index (BMI) 18 kg/m2-25 kg/m2, scheduled for elective video-assisted thoraeoscopic lobectomy, VAS scores at T1 and T2 were lower in group GP than those in group G (P=0.013, P=0.025, respectively), PCIA times during postoperative analgesia 24 h and 48 h were lower in group GP than those in group G (P=0.021, P=0.026, respectively), analgesic volume used during postoperative analgesia 24 h and 48 h were lower in group GP than those in group G (P=0.006, P=0.011, respectively). The level of tumor marker at post-operative were not significantly decreased than preoperative in both groups (P>0.05). Conclusion Patients in group G feel more painful and a higher dosage of dezocine is required to
Are volatile anesthetics neuroprotective or neurotoxic?
Zhiyi Zuo
Medical Gas Research , 2012, DOI: 10.1186/2045-9912-2-10
Abstract: More than 20 millions of patients each year have surgeries in the USA. The majority of these surgeries are performed under general anesthesia. About 80% of them receive volatile anesthetics as their primary anesthetics [1]. Since the first use of ether, a volatile anesthetic, in 1842, volatile anesthetics have be the major class of general anesthetics used in the clinical practice for near 160 years.Although it is still controversial among the experts, it is generally accepted that general anesthesia minimally includes the following components: unconsciousness, insensateness, analgesia and amnesia. Many experts will also add muscle relaxation and bluntness of cardiovascular response to surgical stimulation into the components of general anesthesia. Volatile anesthetics, unlike most intravenous anesthetics, have pharmacological properties to provide all components of general anesthesia [2]. Thus, volatile anesthetics are full general anesthetics and, theoretically, single volatile anesthetic can be used to provide a patient with full general anesthesia for surgery. In addition, volatile anesthetics take effects very quickly. Most patients anesthetized by these drugs recover smoothly and quickly. With the aid of modern equipment, their use is very easy and their concentrations can be accurately monitored. For these reasons, volatile anesthetics have been popular drugs used in clinical practice. Modern volatile anesthetics that are used in the USA include isoflurane (CHF2-O-CHCl-CF3), sevoflurane (CH2F-O-CH-(CF3)2) and desflurane (CHF2-O-CHF-CF3). Halothane (CF3-CHBrCl) was used clinically for more than 40 years and started to be phased out during 1990s as newer volatile anesthetics become popular. All of these volatile anesthetics are halogenated hydrocarbons.In addition to the anesthetic properties, volatile anesthetics have been thought to have neuroprotective effects for a long time [3,4]. Although the potential for volatile anesthetics to induce cell injury has be
Study on the Actuality and the Countermeasures of the Employment of College Students
Zhiyi Fan
International Education Studies , 2008, DOI: 10.5539/ies.v1n2p41
Abstract: The employment of college students has become an issue that draws common concern from the whole society. This paper explores the employment of college students from various angles, finds out the material reasons thereto and put forwards countermeasures for resolving theses problems and development ways.
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