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Search Results: 1 - 10 of 80919 matches for " ZhiQuan Liu "
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Effects of liver inflammation on FibroScan diagnosis of hepatic fibrosis in patients with chronic hepatitis B
LIU Zhiquan
Journal of Clinical Hepatology , 2013,
Abstract: ObjectiveTo investigate the influence of liver inflammation on the ability of the FibroScan non-invasive elastrography scanner to diagnose hepatic fibrosis in patients with chronic hepatitis B (CHB). MethodsA total of 124 CHB patients who received liver biopsy and concomitant liver stiffness measurement (LSM) by FibroScan between June 2011 and February 2012 were enrolled in the study. The liver puncture biopsies were subjected to histological analysis to determine fibrosis stage (S1 to S4, mild fibrosis to severe fibrosis or cirrhosis) and inflammation grade (G1 to G4, low to high extent of inflammation). Differences between groups were assessed by Kruskal-Wallis H test or Mann-Whitney U test. The correlations between LSM and fibrosis stages and inflammation grades were evaluated by Spearman’s rank correlation coefficient. Results The progressive fibrosis stages were accompanied by increased inflammatory grades, such that the significant majority of S1 samples showed G1 inflammation (81.8%, n=55; P<0.01), of S2 showed G2 inflammation (54.2%, n=13; P<0.01), of S3 showed G3 inflammation (47.4%, n=9; P<0.05), and of S4 showed G3 and G4 inflammation (40.0%, n=6 and 334%, n=5; both P<0.01). LSM and inflammation grade were positively correlated within each fibrosis stage group (P<0.01), suggesting that the degree of liver inflammation affects the FibroScan measured value. ConclusionLiver inflammation influences LSM by FibroScan and may impact the ability of this technology to diagnose hepatic fibrosis, with more severe inflammatory activity affecting the LSM to a greater extent.
A New MLS Chaotic System and its Backstepping Sliding Mode Synchronization Control
Liang Shan,Zhong Liu,Zhiquan Wang
Journal of Computers , 2010, DOI: 10.4304/jcp.5.3.456-463
Abstract: A new four-dimensional system is proposed in this paper, which is named modified Lorenz-Stenflo (MLS) system. The system is constructed by replacing one of quadratic nonlinear terms of Lorenz-Stenflo system with a piecewise linear (PWL) function. The simple structure makes the MLS system much easier to be implemented with electronic circuits. Based on adaptive control and sliding mode control methods, an adaptive sliding mode controller is derived to synchronize two MLS chaotic systems. Meanwhile the uncertain parameters in response system are identified. The error systems are deduced by backstepping method. Numerical simulations are used to verify the effectiveness of the proposed controller.
Influence Factor Analysis on Strength of Lime-Fly Ash Loess  [PDF]
Yufen Zhang, Zhiquan Zhang
Engineering (ENG) , 2013, DOI: 10.4236/eng.2013.56068
Abstract: Lime-fly ash loess is composed of fly ash, lime and loess. It is a new material in subgrade backfill. Main factors to influence the strength of lime-fly ash loess are age, amount of fly ash and lime, ratio of fly ash to lime (1:K), and moisture content. In order to observe the effect of each factor influencing the strength of lime-fly ash loess and find out the relationship between each other, this paper adopted orthogonal test design to conduct unconfined compression tests. The result shows that 90d strength can be considered to calculate the strength of lime-fly ash loess in practice. And the most important factor to influence the 90d strength of lime-fly ash loess is the amount of fly ash and lime, the second is moisture content, and then is the ratio of fly ash to lime (1:K). These achievements are significant to the design and application of lime-fly ash loess in subgrade construction of loess areas.
Interferon-gamma ELISPOT for the screening and diagnosis of latent tuberculosis infection in healthy population of China  [PDF]
Yi Peng, Fangfang Yang, Lin Zhou, Meigui Zhao, Yan Li, Yuhong Huang, Juan Wang, Lirong Huang, Dan Xie, Zhiquan Tu, Weiling Lin, Jinhong Liu, Qiu Zhong, Xiaomin Lai
Advances in Bioscience and Biotechnology (ABB) , 2012, DOI: 10.4236/abb.2012.33036
Abstract: The aim of this study was to analyze the combination of three kinds of in-house IFN-γ ELISPOT using peptide A53 and peptide mixtures (E6 + E7 and E6 + E7 + C14) with tuberculin skin test (TST) to detect latent TB infection (LTBI) in China. A total of 788 healthy people were recruited and analyzed by three kinds of IFN-g ELISPOT, 581 of them had TST results, of which 147 samples were also compared with the T- SPOT.TB test. The positive detection rates for T- SPOT.TB and three kinds of IFN-γ ELISPOT with A53, E6 + E7 and E6 + E7 + C14 were 14.28% (21/147), 29.43% (171/581), 23.24% (135/581) and 28.40% (165/581), respectively. These results were significantly lower than the positive TST results, which were positive in 82.99% (122/147) and 75.73% (440/ 581), respectively. The positive detection rates of three kinds of IFN-γ ELISPOT (31.60%, 26.65% and 32.11% in 788 cases, respectively) could better reflect over 40.00% of Mycobacterium tuberculosis (MTB) infection rate in China. Detection rates between contacts and non-contacts by three kinds of IFN-γ ELIS-POT were not significantly different (p > 0.05). It can be seen that the three kinds of in-house IFN-γ ELIS- POT might be used as a complementary tool of T- SPOT.TB for detecting LTBI in the healthy population of China.
Scientific design and preliminary results of three-dimensional variational data assimilation system of GRAPES
JiShan Xue,ShiYu Zhuang,GuoFu Zhu,Hua Zhang,ZhiQuan Liu,Yan Liu,ZhaoRong Zhuang
Chinese Science Bulletin , 2008, DOI: 10.1007/s11434-008-0416-0
Abstract: The scientific design and preliminary results of the data assimilation component of the Global-Regional Prediction and Assimilation System (GRAPES) recently developed in China Meteorological Administration (CMA) are presented in this paper. This is a three-dimensional variational (3DVar) assimilation system set up on global and regional grid meshes favorable for direct assimilation of the space-based remote sensing data and matching the frame work of the prediction model GRAPES. The state variables are assumed to decompose balanced and unbalanced components. By introducing a simple transformation from the state variables to the control variables with a recursive or spectral filter, the convergence rate of iteration for minimization of the cost function in 3DVar is greatly accelerated. The definition of dynamical balance depends on the characteristic scale of the circulation considered. The ratio of the balanced to the unbalanced parts is controlled by the prescribed statistics of background errors. Idealized trials produce the same results as the analytic solution. The results of real data case studies show the capability of the system to improve analysis compared to the traditional schemes. Finally, further development of the system is discussed.
Design and implementation of a heterogeneous distributed database system
Design and Implementation of a Heterogeneous Distributed Database System

Zhiquan Jin,Chengfei Liu,Zhongxiu Sun,Xiaofang Zhou,Peipei Chen,Jianming Gu,
Jin Zhiquan
,Liu Chengfei,Sun Zhongxiu,Zhou Xiaofang,Chen Peipei,Gu Jianming

计算机科学技术学报 , 1990,
Abstract: This paper introduces a heterogeneous distributed database system called LSZ system, where LSZ is an abbreviation of Li Shizhen, an ancient Chinese medical scientist. LSZ system adopts cluster as distributed database node (or site). Each cluster consists of one or several microcomputers and one server. The paper describes its basic architecture and the prototype implementation, which includes query processing and optimization, transaction manager and data language translation. The system provides a uniform retrieve and update user interface through global relational data language GRDL. This research is supported by National Natural Science Foundation under Grant 6863051.
Effect of filter-feeding fish silver carp on phytoplankton species and size distribution in surface water: A field study in water work
Effect of filter-feeding fish silver carp on phytoplankton species and size distribution in surface water: A field study in water works

Hua M,Fuyi Cui,Zhiquan Liu,Zhenqiang Fan,Wenjie He,Peijun Yin,
Hua M
,Fuyi Cui,Zhiquan Liu,Zhenqiang Fan,Wenjie He,Peijun Yin

环境科学学报(英文版) , 2010,
Abstract: Silver carp were introduced into the pre-sedimentation pond to control excessive phytoplankton in raw water.The effectiveness of the filter-feeding silver carp on phytoplankton control and the effect of silver carp on phytoplankton community were investigated.The results showed that Microcystis could be effectively removed by silver carp stocked in the pre-sedimentation pond,and simultaneously,the concentration of single-cell phytoplankton increased obviously.The difference in phytoplankton species and sing...
Direct assimilation of satellite radiance data in GRAPES variational assimilation system
GuoFu Zhu,JiShan Xue,Hua Zhang,ZhiQuan Liu,ShiYu Zhuang,LiPing Huang,PeiMing Dong
Chinese Science Bulletin , 2008, DOI: 10.1007/s11434-008-0419-x
Abstract: Variational method is capable of dealing with observations that have a complicated nonlinear relation with model variables representative of the atmospheric state, and so make it possible to directly assimilate such measured variables as satellite radiance, which have a nonlinear relation with the model variables. Assimilation of any type of observations requires a corresponding observation operator, which establishes a specific mapping from the space of the model state to the space of observation. This paper presents in detail how the direct assimilation of real satellite radiance data is implemented in the GRAPES-3DVar analysis system. It focuses on all the components of the observation operator for direct assimilation of real satellite radiance data, including a spatial interpolation operator that transforms variables from model grid points to observation locations, a physical transformation from model variables to observed elements with different choices of model variables, and a data quality control. Assimilation experiments, using satellite radiances such as NOAA17 AMSU-A and AMSU-B (Advanced Microwave Sounding Unit), are carried out with two different schemes. The results from these experiments can be physically understood and clearly reflect a rational effect of direct assimilation of satellite radiance data in GRAPES-3DVar analysis system.
DNA-protein interaction at erythroid important regulatory elements of MEL cells byin vivo footprinting
Xinjun Ji,Depei Liu,Dongdong Xu,Lei Li,Jing Wang,Zhiquan Liang
Chinese Science Bulletin , 2000, DOI: 10.1007/BF02887183
Abstract: Using ligation-mediated PCR method to study the status of DNA-protein interaction at hypersensitive site 2 of locus control Region and βmaj promoter of MEL cell line before and after induction, MEL cell has been cultured and induced to differentiation by Hemin and DMSO, then the live cells have been treated with dimethyl sulfate. Ligation mediated PCR has been carried out following the chemical cleavage. The results demonstrate that before and after induction, the status of DNA-protein interaction at both hypersensitive site 2 and βmaj promoter change significantly, indicating that distal regulatory elements (locus control region, hypersensitive sites) as well as proximal regulatory elements (promoter, enhancer) of β-globin gene cluster participate in the regulation of developmental specificity.
Low-temperature selective catalytic reduction of NO with NH3 over Ce-Mn/TiO2 catalyst

LIU Wei,TONG Zhiquan,LUO Jie,

环境科学学报 , 2006,
Abstract: 用浸渍法制备了Ce-Mn/TiO2催化剂,考察了其在O2存在条件下选择性催化还原(SCR)NO的活性和抗SO2及H2O毒化的性能.结果表明,反应温度、空间速度、NO进口浓度和NH3/NO摩尔比对NO转化率的影响较小;在120℃的低温条件下,该催化剂显示了良好的催化活性,NO的转化率始终保持在95%以上.该催化剂有良好的同时抗SO2和H2O毒化能力.
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