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Search Results: 1 - 10 of 142298 matches for " Zhen-Lin Zhang "
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2,5-Bis[2-(4-methylphenyl)ethynyl]benzyl methacrylate
Zhen-Lin Zhang,Hai-Quan Zhang
Acta Crystallographica Section E , 2011, DOI: 10.1107/s1600536811029631
Abstract: In the title bis-tolane derivative, C29H24O2, the central benzene ring forms dihedral angles of 29.12 (9) and 26.46 (9)° with the other two benzene rings. The dihedral angle between two terminal benzene rings is 55.58 (8)°.
An Omni-Directional and Band-Notched Ultra Wideband Antenna on Double Substrates Crossing
Zhen-Lin Liao;Fu-Shun Zhang;Guitao Xie;Weigang Zhai;Li-Na Chen
PIER C , 2011, DOI: 10.2528/PIERC11050802
Abstract: A novel Ultra Wideband (UWB) antenna on double substrates crossing is presented in this paper. Based on conical antenna and microstrip patch UWB antenna, the proposed antenna is omni-directional, band-notched and easy to be fabricated. It operates from 2.6 GHz to 12 GHz with low Voltage Standing Wave Ratio (VSWR<2), excluding a notch-band of 5.8 GHz. Except for good performance of VSWR, the proposed antenna keeps its radiating beam at about θ = 45°in E-plane through the whole band. The UWB antenna is fed by a coaxial probe through a SMA connector. The length of the proposed monopole element above the ground is slightly less than λ/4 of the lowest frequency. The simulated and measured results of the VSWR, he gain and the radiation patterns for the proposed antennas are presented and discussed. Good agreement between simulated and measured results is demonstrated.
Phenotype and Genotype Analysis of Chinese Patients with Osteogenesis Imperfecta Type V
Zeng Zhang, Mei Li, Jin-Wei He, Wen-Zhen Fu, Chang-Qing Zhang, Zhen-Lin Zhang
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0072337
Abstract: Osteogenesis imperfecta (OI) type V is an autosomal-dominant disease characterized by calcification of the forearm interosseous membrane, radial head dislocation, a subphyseal metaphyseal radiodense line, and hyperplastic callus formation. The causative mutation, c.-14C>T in the 5'-untranslated region of IFITM5, was recently discovered to be involved in this disease. However, in spite of the little genotypic variability, considerable phenotypic variability has been recognized in two cohorts of patients, the majority of whom were Caucasians. Using exome sequencing, we identified the same heterozygous mutation in four Chinese families with OI type V. This study confirms the molecular cause of OI type V and describes the phenotype of Chinese patients with this disorder. In conclusion, the phenotype of Chinese patients was generally similar to that of Caucasian patients.
Effect of branched-chain amino acids, valine, isoleucine and leucine on the biosythesis of bitespiramycin 4"-O-acylspiramycins
Li, Zhen-Lin;Wang, Yong-Hong;Chu, Ju;Zhuang, Ying-Ping;Zhang, Si-Liang;
Brazilian Journal of Microbiology , 2009, DOI: 10.1590/S1517-83822009000400003
Abstract: bitespiramycin, a group of 4"-o-acylated spiramycins with 4"-o-isovalerylspiramycins as the major components, was produced by recombinantspiramycin-producing strain streptomyces spiramyceticus harboring a 4"-o-acyltransferase gene. the experiment was initially performed in synthetic medium with 0.5 g l-1 valine, isoleucine or leucine feeding at 36 h cultivation. when valine was fed, the biological titer of bitespiramycin was 45.3% higher than that of the control group, but the relative content of total isovalerylspiramycin components decreased by 22.5%. in the case of ilecine, the biological titer of bitespiramycin and the total isovalerylspiramycins alone were 85% and 72.1% of the control group, respectively. in contrast, the relative content of other acylated spiramycins increased by 54.41%. however, leucine feeding increased the relative content of total isovalerylspiramycins by 41.9% while the biological titer of bitespiramycin was nearly equal to that of the control group. the improvement effect of leucine on the biosynthesis of isovalerylspiramycins was further confirmed by feeding of 2.0 g l-1 leucine to the culture with complex medium. after batch feeding with a total amount of 2.0 g l-1 leucine to the culture from 70 h to 90 h, the biological titer of bitespiramycin was almost unreduced, and the final relative content of total isovalerylspiramycins increased from 31.1% to 46.9%.
High Prevalence of Vitamin D Insufficiency in China: Relationship with the Levels of Parathyroid Hormone and Markers of Bone Turnover
Han-Kui Lu,Zeng Zhang,Yao-Hua Ke,Jin-Wei He,Wen-Zhen Fu,Chang-Qing Zhang,Zhen-Lin Zhang
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0047264
Abstract: There is a lack of large-scale studies on vitamin D status and its relationship to parathyroid hormone (PTH) and bone turnover markers in adults living in Shanghai. The objectives were to determine the prevalence of vitamin D insufficiency in Shanghai and to investigate the relationship of 25(OH)D with parathyroid function and bone turnover markers. This cross-sectional study involved 649 men and 1939 women aged 20–89 years who were randomly sampled in Shanghai. Serum concentrations of 25(OH)D, PTH, albumin, and bone turnover markers were measured. During the winter season, the prevalence of vitamin D insufficiency (<30 ng/mL) was 84% in males and 89% in females. The prevalence of vitamin D deficiency (<20 ng/mL) was 30% in males and 46% in females. With increasing serum 25(OH)D concentrations categorized as <10, 10–20, 20–30, and ≥30 ng/mL, the mean PTH and bone turnover markers levels gradually decreasd in both sexes (p<0.001). There was an inverse relationship between the serum 25(OH)D and PTH concentrations in both genders, but no threshold of 25(OH)D at which PTH levels plateaued was observed. There were modest but significantly inverse relationships between the levels of 25(OH)D and bone turnover markers, but no plateau was observed for serum 25(OH)D levels up to 40 ng/mL.
Preparation and Microstructure of Nano MoSi2-SiC Composite by Melt Infiltration Process
反应熔渗法制备纳米 MoSi2-SiC复合材料

ZHANG Xiao-Li,JIN Zhi-Hao,FENG Yao-Rong,ZHAO Wen-Zhen,L Zhen-Lin,HUO Chun-Yong,
张小立

无机材料学报 , 2007,
Abstract: MoSi2-SiC composite was successfully prepared by Si melt infiltration into Mo+C preforms. The crystal grain size of the resultant matrix is 150-600nm, and the size of SiC phase produced is 30-160nm which disperses homogeneously in the matrix. The strength of the composite is 214.8MPa, the toughness is 4.1MPa·m1/2, these mechanical properties are higher than that of single phase MoSi2. TEM results show lots of stacking faults, some dislocations, and twins existing in the composite.
Scattering behaviours to the two-dimensional electron gasinduced by the Al composition fluctuation in AlxGa1-xNbarrier in AlxGa1-xN/GaN heterostructures

Wang Yan,Shen Bo,Xu Fu-Jun,Huang Sen,Miao Zhen-Lin,Lin Fang,Yang Zhi-Jian,Zhang Guo-Yi,

中国物理 B , 2009,
Abstract: This paper reports that cathodoluminescence (CL) measurements have been done to study the alloy fluctuation of the Al$_{0.3}$Ga$_{0.7}$N layer in Al$_{0.3}$Ga$_{0.7}$N/GaN heterostructures. The CL images and linescanning results demonstrate the existence of compositional fluctuation of Al in the Al$_{0.3}$Ga$_{0.7}$N barrier. A model using a $\delta $-shape perturbation Hamilton function has been proposed to simulate the scattering probability of the two dimensional electron gases (2DEG) induced by Al composition fluctuation. Two factors, including conduction band fluctuation and polarization electric field variation, induced by the Al composition fluctuation have been taken into account. The scattering relaxation time induced by both factors has been estimated to be 0.31~ns and 0.0078~ns, respectively, indicating that the variation of the piezoelectric field is dominant in the scattering of the 2DEG induced by Al fluctuation.
The edges and terrace effect of Ag particles on optical resonance absorption property

Zhao Ya-Li,Gui Ya-Qiang,Zhang Zhen-Lin,Ma Fu-Hu,Xu Xiao-Li,Xu Xiao-Liang,

中国物理 B , 2011,
Abstract:
非拔牙矫治上牙列重度拥挤1例
Non-extraction Treatment for Severe Dentition Crowding: A Case Report

牟兰,张晓波,徐庚池,葛振林
MU Lan
, ZHANG Xiao-bo,XU Geng-chi, GE Zhen-lin.

- , 2016, DOI: 10.11839/kqyxzh.2016.01.02
Abstract: 摘要 目的:分析重度拥挤非拔牙矫治病例。方法:用磨牙推进器联合MBT直丝弓技术排齐牙列。结果:矫治结束后患者直面型维持较好,上下牙列排齐。结论:在生长发育高峰期,磨牙推进器可有效矫治牙列重度拥挤
No association of the polymorphisms of the frizzled-related protein gene with peak bone mineral density in Chinese nuclear families
Gao Gao, Zhen-Lin Zhang, Jin-Wei He, Hao Zhang, Hua Yue, Wei-Wei Hu, Jie-Mei Gu, Wen-Zhen Fu, Yun-Qiu Hu, Miao Li, Yu-Juan Liu, Jin-Bo Yu
BMC Medical Genetics , 2010, DOI: 10.1186/1471-2350-11-1
Abstract: We recruited 1,260 subjects from 401 female-offspring nuclear families and 1,296 subjects from 427 male-offspring nuclear families and genotyped four tagging single nucleotide polymorphisms (tagSNPs) (rs6433993, rs409238, rs288324, and rs4666865) spanning the entire FRZB gene. The SNPs rs288326 and rs7775, which are associated with hip osteoarthritis, were not selected in this study because of their low minor allele frequencies (MAFs) in Chinese people. The quantitative transmission disequilibrium test (QTDT) was used to analyze the association between each SNP and haplotype with peak BMD in female- and male-offspring nuclear families.In the female-offspring nuclear families, we found no evidence of an association between either single SNPs or haplotypes and peak BMD in the spine or hip. In the male-offspring nuclear families, no within-family association was observed for either SNPs or haplotypes, although a significant total association was found between rs4666865 and spine BMD (P = 0.0299).Our results suggest that natural variation in FRZB is not a major contributor to the observed variability in peak BMD in either Chinese females or males. Because ethnic differences in the FRZB genotypes may exist, other studies in different population are required to confirm such results.Osteoporosis is a skeletal disorder characterized by fragile bones susceptible to low trauma fractures. One of the most important determinants for osteoporotic fracture is low bone mineral density (BMD) [1,2], which is under strong genetic control, with heritability estimates ranging from 50% to 80% [3-5]. Osteoporosis is associated with peak bone mass achieved during early adulthood and the rate of bone loss later in life. Identification of genes underlying peak BMD may be useful in predicting the risk of low bone mass and osteoporosis in later life.The Wnt/beta-catenin signaling pathway plays an important role in skeletal development and growth [6,7]. In this pathway, Wnt signaling is transmi
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