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Search Results: 1 - 10 of 1746 matches for " Zahra Khalili Matinzadeh "
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A Case of Congenital Leukemia with Nasal Hemorrhage and Jaundice
Zahra Khalili Matinzadeh,Zohreh Kavehmanesh,Susan Amirsalari,Shahla Afsharpeyman
Iranian Journal of Pediatrics , 2010,
Frequency of Multiple Pregnancy and its Complications in Three Educational Hospitals,Tehran
Zohreh Kavehmanesh,Susan Amirsalari,Mohammad Torkaman,Zahra Khalili Matinzadeh
Iranian Journal of Pediatrics , 2007,
Abstract: Objective: Multiple pregnancies is a high-risk pregnancy since it is associated with increased perinatal and maternal problems .The aim of our study to determine the frequency of multiple pregnancy and its maternal and perinatal complications.Material & Methods: In a cross –sectional study we assessed 94 multiple pregnancies and 199 neonates in three educational hospitals in Tehran (Baghiyatallah , Najmie and Mahdie) in first half of 2006. The information was collected from hospital registries of mothers and their neonates.Findings: Of 4584 deliveries, 84(1.8%) were twins, 9(0.19%) were triplets and 1(0.02%) was quadruplets. 59 (62.7%) of mothers had preterm labor and 14 (14.8%) had pre-eclampsia. We found discordant birth weigh ≥ 20% in 24 (25.4%) and TTTS (Twin-To-Twin Transfusion) in 3(3.1%) of mothers .174 (87.4%) of all neonates were admitted in NICU or pediatric department. The frequency of mortality and respiratory distress in neonates were 27 (13.5%) and 107 (53.7 %), respectively.39 (19.5%) of neonates had Apgar scores<7 and seizure was not observed in neonates. 65 (32.6%) of neonates were normal weight (> 2500 gram), 104 (52.4%) LBV, 21(10.5%) VLBV and 9(4.5%) ELBV. Hypocalcaemia, hypoglycemia and anemia detected in 45 (22.6%), 24 (12%) and 48 (24.1%) of neonates respectively.Conclusion: Regard to increasing the prevalence of multiple pregnancies, better use of infertility modalities, early diagnosis of the multiple pregnancies, prevention of preterm birth, close fetal surveillance, atraumatic labor and delivery can improve maternal and perinatal outcome.
Tehran University of Medical Sciences: Participation in Twenty Five Percent of Pediatric Science Production in Iran
Susan Amirsalari,Zahra Khalili Matinzadeh,Shahla Afsharpayman,Morteza Javadipour
Iranian Journal of Pediatrics , 2008,
Abstract: Objective: Scientific articles are indicators of research interests and efforts in every country. The aim of our study was to compare the scientific output between universities of medical sciences in Iran on pediatrics in the Pubmed database.Methods: In a descriptive study, we searched in Pubmed in order to assess the Iranian pediatrics publications with these words: "(Pediatric [*MeSH] OR Neonate [MeSH] OR Newborn[MeSH] OR Infant [MeSH] OR Child [MeSH] OR Children [MeSH] OR Adolescent[MeSH] OR Adolescence [MeSH])" AND (Iran [*AD] OR Iranian [AD] OR Persian [AD]). The identified articles were published May 1957 to December 2007 and we selected all articles from universities of medical sciences in Iran. We extracted year of publication, affiliation of authors and impact factor from hard copy of articles.Findings: From 819 papers published, 565 were authored by members of universities of medical sciences. Tehran University of Medical Sciences with 142 articles (17.3% of all, 25.1% from publications of universities of medical sciences) held the first place, Shiraz University of Medical Sciences with 116 (14.2% of all, 20.5% from publications of universities of medical sciences) the second place and Shaheed Beheshti University of Medical Sciences with 88 (10.7% of all, 15.5% from publications of universities of medical sciences) the third place. Regarding Impact Factors (IF) Tehran, Shaheed Beheshti and Shiraz Universities of Medical Sciences with 153, 93 and 81 were in the first, second and third place, respectively.Conclusion: Tehran University of Medical Sciences had twenty five percent of pediatric science production in Iran. This university had published higher number of papers on pediatrics among universities of medical sciences in Iran.
Leukocyte Adhesion Deficiency: Report of Two Family Related Newborn Infants
Zohreh Kavehmanesh,Zahra Khalili Matinzadeh,Susan Amirsalari,Mohammad Torkaman
Acta Medica Iranica , 2010,
Abstract: "nLeukocyte adhesion deficiency type 1 (LAD 1) is an autosomal recessive hereditary disorder resulting from deficiency of CD18, characterized by recurrent bacterial infections. We report two consanguineous patients with Leukocyte adhesion deficiency type 1( LAD1). These two infant boy patients were referred to us, within a short period of time, with the complaints of recurrent infections at the age of 38 and 75 days -old, respectively. Parents of two patients were first cousins and their grandmothers also were first cousins. The history of delayed umbilical cord separation was shown in both patients. Patient 1 had history of omphalitis, conjunctivitis, skin lesion of groin area and abscess formation of vaccination site, and had infective wound of eye-lid at the last admission. Patient 2 had history of omphalitis and soft tissue infection of right wrist at the last admission. Laboratory findings showed marked leukocytosis and low CD18 levels (6.6% in Patient 1 and 2.4 % in Patient 2). In Patient 1 recurrent infections were treated with antibiotic regimens and received bone marrow transplantation but Patient 2 died because of septicemia, generalized edema, ascites and progression to acute renal failure at 4 months of age. Due to considerable rate of consanguineous marriages in parents of Leukocyte adhesion deficiency patients, sequence analysis especially for prenatal diagnosis in subsequent pregnancies and genetic counseling is recommended.
Z. Khalili-Matinzadeh
Acta Medica Iranica , 2006,
Abstract: The term congenital hypopituitarism defines deficiency of all of the pituitary hormones. Hypoglycemia and microphallus (in males) are common findings, and some infants have shown evidence of the neonatal hepatitis syndrome. We report a case of congenital panhypopituitarism with deficiency of six major hormones and association with severe hypoglycemia, impaired liver function tests and congenital heart disease.
S. Amirsalari,Z. Kavehmanesh,Z. Khalili Matinzadeh
Iranian Journal of Child Neurology , 2006,
Abstract: Introduction:Infantile spasms (IS) is an age specific epileptic syndrome. Due to poorresponse of IS to conventional antiepileptic drugs, scientists are always onthe lookout for newer, more effective drugs to treat the condition.Materials & Methods:In this study, 50 infants with IS symptoms, aged between 2-24 months, wererandomly divided into two equal groups, each treated either with Vigabatrinor ACTH (long acting Tetracosectide); the results for clinical efficacy ofmedication and drug side effects were compared.Results:After the sixth week of treatment, in the Vigabatrin group, 28% completeremission and 40% reduction in seizure frequencies was seen, while in theTetracosectide group there were 40.9% complete remission and 45.5%reduction in seizure frequencies, showing no significant difference betweenthe clinical responses found in the two groups (P=0.44).Conclusion:Vigabatrin effeciacy is similar to Tetracosectide, but since it is impossible toevaluate visual field constriction, a probable irreversible side effect of Vigabatrin, It's better to use Tetracosectide for the first line in the treatment of IS .
"The effect of fluid supplementation on serum bilirubin level during phototerapy in term infants "
Torkaman M,Afsharpeyman SH,Khalili Matinzadeh Z,Amirsalary S
Tehran University Medical Journal , 2007,
Abstract: Background: Jaundice is a common and benign problem in neonatal period. Several therapeutic procedures for decreasing of serum bilirubin level has been recommended. phototherapy is most common them. Our goal Form this study is the evaluation of serum therapy effects in decreasing of serum bilirubin concentration in icteric infants that are treated with phototherapy. Methods: This is a prospective clinical trial in Najmeih Hospital in 2002. In this study 80 term icteric infants with bilirubin level greater than 17 mg/dl were randomized in two groups, both groups underwent phototherapy and in the case group intravenous fluid supplementation was added. There were no significant differences in the mean gestational age, birth weight, hemoglobin, and also in total serum bilirubin level at admission in the two groups. Results: There were no significant differences in the mean rate of of serum bilirubin level decline during first 24 and 48 hours of hospitalization and also the time of bilirubin decreasing to less than 15 mg/dl and the length of hospitalization in two groups. Conclution: Our study showed intravenous fluid supplementation could be limited to special cases of neonatal icter such as moderate to severe dehydration.
A Comparison Between the Effects of Estrogen and Soy Extract on Chronic Pain in Male Rats
Zahra Kiasalari,Mohsen Khalili
Iranian Journal of Pharmaceutical Research , 2008,
Abstract: In addition to its effect on reproductive organs, estrogen exhibits complex effects on brain structure, function and behavior. In this regard, the influence of gonadal hormones especially estrogens on nociception has recently been accepted. Soybean is known as an important phytoestrogen containing plant that is used as an alternative for estrogen replacement therapy. In this study, the influences of soy extract and estrogen on formalin-induced nociception in male rats were examined. In the first experiment, the effect of soy extract added to drinking water (60 mg/kg per day) on the nociception was assessed and compared with a control group (with soy-free drinking water). There was a significant decrease in nociception in rats that received soy extract for two weeks. Furthermore, different doses of soy extract (50, 150 and 200 mg/kg) were injected subcutaneously 30 min before formalin test to assess its effect on acute and chronic pain perception. It was observed that different doses of soy extract had similar antinociceptive effects that were significantly different from saline injected control group. In other experiment, rats treated with a single dose of 150 μg of 17-β estradiol (s.c.) 48 h prior to the formalin test, to be compared with a control group just received estrogen vehicle (DMSO). Acconding to our results Estradiol did not show any significant effect on pain suppression. These results suggest that the antinociceptive effect of soy extract on chronic pain is not aresult of its phytoestrogenic activitiy, it might atherefore be related to other substances within soy extract.
First record of the family Pseudocerotidae (Platyhelminthes, Polycladida, Cotylea) from the Persian Gulf, Iran
Zahra Khalili,Hassan Rahimian,Jamile Pazooki
ZooKeys , 2009, DOI: 10.3897/zookeys.31.136
Abstract: In this paper, two species of cotylean Platyhelminthes are recorded for the first time from Qeshm Island, Persian Gulf, Iran. Pictures are taken from living specimens to illustrate shape and colour, and stained sections and drawings are used to describe shape and organisation of some organs. Morphological characters of Persian Gulf specimens of Tytthosoceros lizardensis Newman & Cannon, 1996 are compared to those of the type specimens of this species.
Effects of alcoholic extract of Zingiber officinalis rhizome on acute and chronic inflammation and pain in rats
Mohsen Khalili,Zahra Kiasalari,Ehsan Farhadi,Mahshid Agah
Koomesh , 2011,
Abstract: Introduction: Patients with chronic, painful diseases often seek alternative therapy. The rhizome of Zingiber (Z) officinalis is a common constituent of diets around the world and its extracts have been reported to exhibit several pharmacological activities. We investigated the effects of alcoholic Zingiber oficinalis rhizome extract on two different models of acute and chronic inflammation and pain. Material and Methods: Formalin, xylen and acetic acid were used to induce acute inflammation in paw, ear and peritoneum, respectively. The amount of Evans' blue dye leakage into these tissues was used as an index of acute inflammation . For chronic inflammation, a piece of sterile cotton (30 mg) was impalnated into the groin region for a period of seven days. Following, t he weight of the cotton piece before implantation is subtracted from the weight of the dried piece and used as an index of chronic inflammation. Finally, acute and chronic pain assessment was carried out via the formalin test protocol . Results: In acute inflammation model, the formalin-induced inflammation in paw and peritoneum was significantly (P <0.05) reduced by the extract of Z. oficinalis rhizome at doses of 200 and 400 mg/kg. Also, the extract at the dose of 400mg/kg significantly (P<0.05) reduced the paw diameter. In chronic inflammation model, the extract at the dose of 200 mg/kg significantly (P< 0.01) dimished inflammation. Finally, both acute and chronic pain significantly (P< 0.05) suppressed by the extract at the dose of 200 mg/kg. Conclusion: Findings of this study indicate that alcoholic extract of Z. oficinalis has anti-inflammatory and antinociceptive effects. Thus, using the extract of Z. oficinalis could be a potential alternative therapy in ameliorating inflammation and pain in patients suffering from chronic diseases.
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