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Search Results: 1 - 10 of 104257 matches for " ZHANG MingJie "
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Comparison between the Isotope Tracking Method and Resistivity Tomography of Earth Rock-Fill Dam Seepage Detection  [PDF]
Mingjie Zhao, Hui Wang, Xiao Sun, Yao Zhang
Engineering (ENG) , 2011, DOI: 10.4236/eng.2011.34045
Abstract: This paper compares the different inversion results of three different earth rock-fill dam models with the actual leakage passages by performing isotope tracing tests and resistivity tomographic tests. The accuracy of the experimental results is evaluated, and the characteristics of these two methods are analyzed. As a result, some significant references are offered for earth rock-fill dam’s hidden defects detection. The experimental results show that the leakage and the direction of the seepage can be judged by isotope tracing tests, meanwhile, the degree of the leakage can be confirmed through the determination of the horizontal seepage velocity and the vertical seepage velocity, but it is difficult to properly determine the position of leakage passages and the range of leakage. Relatively speaking, the positions of the leakage passages can be accurately and directly displayed through resistivity tomographic tests. The experiment results show that the resistivity tomographic method is much better than isotope tracing method with regard to earth rock-fill dam’s hidden defects detection, and the resistivity tomographic method expresses much more convenience and much higher precision than isotope tracing method.
Application of 3D Electrical Resistivity Tomography for Diagnosing Leakage in Earth Rock-Fill Dam  [PDF]
Xin Zhang, Mingjie Zhao, Kui Wang, Pan Liu, Huan Liu
Engineering (ENG) , 2016, DOI: 10.4236/eng.2016.85023
Abstract: The leakage occurs during operation of the dam in Liuhuanggou reservoir. It’s a threat to the safety of the people’s lives and property in downstream. In order to eliminate the hidden danger of reservoir, ensure the safety of the dam, play better the function of flood control and water storage of the reservoir etc., we apply the 3D electrical resistivity tomography detecting technology and volume rendering image processing technology, make the measurement in field, process the data and combine the field survey to find out the leakage channels inside the dam. The results show that the 3D resistivity images appear the low resistivity zone corresponding with the leakage channels. There are two main leakage channels that come from different location inside the dam. It is feasible to diagnose the leakage in earth rock-fill dam by applying 3D electrical resistivity tomography.
Productivity Testing Design Method of Multi-Factor Control for Unconsolidated Sandstone Gas Reservoir  [PDF]
Muwang Wu, Hao Liang, Mingjie Zhang, Dianqiang Sun, Peng Zhong
Engineering (ENG) , 2016, DOI: 10.4236/eng.2016.811073
Abstract: Reservoir safety, testing-string safety, and flow control are key factors that should be considered in deep-water unconsolidated sandstone gas well testing work system. Combined with the feature of testing reservoir, pipe string type and sea area, the required minimum testing flow rate during cleaning up process, as well as minimum test flow rate without hydrate generation, pipe string erosion critical production, the maximum testing flow rate without destroying sand formation and the minimum output of meeting the demand of development was analyzed; based on the above critical test flow rates, testing working system is designed. Field application showed that the designed work system effectively provided good guidance for field test operations; no sand production or hydrate generation happened during the test process; the test parameter evaluated the reservoir accurately; the safe and efficient test operation was achieved.
Development of Dengue virus type 2 replicons capable of prolonged expression in host cells
Xiaowu Pang, Mingjie Zhang, Andrew I Dayton
BMC Microbiology , 2001, DOI: 10.1186/1471-2180-1-18
Abstract: Dengue constructs which lack major structural proteins replicate intracellularly in tissue culture. These replicons are capable of prolonged expression of Dengue virus non-structural proteins for at least seven days in culture.Dengue virus genomes lacking major structural proteins can, like other flaviviruses, replicate intracellularly and express virus non-structural proteins with minimal toxicity to host cells. These findings pave the way for the development of dengue virus replicons as a form of live, attenuated virus vaccine.The mosquito-borne flavivirus, Dengue, is estimated to cause in each year 100 million cases of Dengue fever (DF), 500,000 cases of Dengue Hemorrhagic fever (DHF) and 25,000 deaths, with 2.5 billion people at risk [1]. Although a successful vaccine against the prototypical flavivirus, yellow fever (YF) virus, has been in use since the 1930s and vaccines to two other flaviviruses, Japanese encephalitis (JE) virus and tick-borne encephalitis (TBE) virus are currently available, there is as yet no Dengue vaccine approved for use [2].Dengue virus has a typical flavivirus genome structure, as described in Figure 1A. The structural proteins, C, prM (M) and E, are involved in packaging, export and subsequent entry. The non-structural proteins, NS1, NS2A, NS2B, NS3, NS4A, NS4B and NS5 include an RNA-directed RNA polymerase, and a protease function involved in cleaving certain positions of the long viral polyprotein which contains all the viral genes [3,4].The four serotypes of Dengue virus ("1" through "4") share approximately 60%–74% amino acid residue identity with one another in the E gene [5] and induce cross-reacting antibodies [6]. However, neutralizing antibodies to the structural proteins of one serotype of Dengue typically not only fail to provide protection against other serotypes, but appear to cause the enhanced replication of virus seen in Dengue hemorrhagic fever, which is generally seen upon reinfection by Dengue virus of a different s
Development of dengue virus replicons expressing HIV-1 gp120 and other heterologous genes: a potential future tool for dual vaccination against dengue virus and HIV
Xiaowu Pang, Mingjie Zhang, Andrew I Dayton
BMC Microbiology , 2001, DOI: 10.1186/1471-2180-1-28
Abstract: We cloned into a Δpre-M/E dengue virus replicon genes for either green fluorescent protein (GFP), HIV gp160 or HIV gp120 and tested the ability of these constructs to express dengue virus proteins as well as the heterologous proteins in tissue culture after transfection of replicon RNA.Heterologous proteins were readily expressed from these constructs. GFP and gp120 demonstrated minimal or no toxicity. Gp160 expressing replicons were found to express proteins abundantly at 36 hours post transfection, but after 50 hrs of transfection, few replicon positive cells could be found despite the presence of cellular debris positive for replicon proteins. This suggested that gp160 expressed from dengue virus replicons is considerably more toxic than either GFP or gp120. The successful expression of heterologous proteins, including HIV gp120 for long periods in culture suggests this vector system may be useful as a vaccine vector, given appropriate delivery methods.Despite tremendous progress in developing anti-retroviral drugs to combat HIV, there remains a need for an effective HIV vaccine. This need is particularly pressing in third world countries, where demographics and economics make drug therapy difficult to deliver. Although HIV infection elicits neutralizing antibodies and a cellular immune response against the virus [reviewed in [1] &[2]] and there exist "exposed uninfected" (EU) individuals that appear to have acquired resistance to infection by HIV [3,4], the hallmark of HIV infection is the almost universal inability of humans to mount an immune response that can prevent the eventual development of AIDS.An effective vaccine will require not only the design of effective immunogens, but also the design of optimized protocols of immunogen delivery. As a live, attenuated vaccine for HIV is considered difficult to test and dangerous to implement [1,2,5-9], various alternatives to HIV could be considered as potential "live" vectors for HIV immunogens, including enteric
Combination of NMR spectroscopy and X-ray crystallography offers unique advantages for elucidation of the structural basis of protein complex assembly
Wei Feng,LiFeng Pan,MingJie Zhang
Science China Life Sciences , 2011, DOI: 10.1007/s11427-011-4137-2
Abstract: NMR spectroscopy and X-ray crystallography are two premium methods for determining the atomic structures of macro-biomolecular complexes. Each method has unique strengths and weaknesses. While the two techniques are highly complementary, they have generally been used separately to address the structure and functions of biomolecular complexes. In this review, we emphasize that the combination of NMR spectroscopy and X-ray crystallography offers unique power for elucidating the structures of complicated protein assemblies. We demonstrate, using several recent examples from our own laboratory, that the exquisite sensitivity of NMR spectroscopy in detecting the conformational properties of individual atoms in proteins and their complexes, without any prior knowledge of conformation, is highly valuable for obtaining the high quality crystals necessary for structure determination by X-ray crystallography. Thus NMR spectroscopy, in addition to answering many unique structural biology questions that can be addressed specifically by that technique, can be exceedingly powerful in modern structural biology when combined with other techniques including X-ray crystallography and cryo-electron microscopy.
Zhichen Zhu,Jin Cui,Mingjie Zhang
Acta Crystallographica Section E , 2008, DOI: 10.1107/s1600536808007204
Abstract: In the molecule of the title compound, C28H40N2O2, the tert-butyl group is disordered over two positions; site-occupation factors were kept fixed at 0.5. The morpholine ring has a chair conformation. Intramolecular O—H...N hydrogen bonding results in the formation of a planar six-membered ring, which is oriented at a dihedral angle of 0.70 (3)° with respect to the adjacent aromatic ring. The dihedral angle between the benzene rings is 67.66 (3)°.
The Library Computer Web Construction and Its Importance under 211 Project

Zhang Quan Han Mingjie,

现代图书情报技术 , 2001,
Abstract: In combination with the construction of library computer Web of CAU the authors discusse significance and effect of Web construction on development of their library as common service system of “211 project”.
Searching for a Personality Structure of Chinese: A Theoretical Hypothesis of a Six Factor Model of Personality Traits

Zhang Jianxin,Zhou Mingjie,

心理科学进展 , 2006,
Abstract: Finding a latent structure for personality traits has been consistently one of the focuses in personality research, while finding empirical evidence of culture-general or culture-specific nature for a personality structure is at present one of the important topics in personality research. Therefore, it can be seen that there have disputation over the number of factors (or dimensions) for such a personality structure, and over the adaptability of a structure from one culture to people of another culture. The present paper summarizes various findings resulted from a series of studies on CPAI (Chinese Personality Assessment Inventory) over the past period of 20 years to put forward a Six Factor Model (SFM). Based on the responses to IR and O factor of SFM from the samples of Chinese and American, the paper therefore suggest that the number of factors and culture-specific nature in any of the existing personality structures be only meaningful in terms of methodology and epistemology adopted by its researchers. The only way to find a personality structure of culture-general or culture-specific is to let personality psychologists of many cultural backgrounds work together equally.
Social Development and the Changes of Chinese People''''s Personalities

Zhou Mingjie,Zhang Jianxin,

心理科学进展 , 2007,
Abstract: 再利用本土化的人格工具CPAI,对中国社会现代化发展时间进程和城市现代化水平差异与中国人群体人格特征模式之间的关系进行了探讨。研究结果表明,中国人的群体人格特征正在随着社会发展而成现出相应的变化,表现为更为多元化、个性张扬、人际关系的束缚在减弱。当然,现代化进程的时间和空间特征对人格变化的影响可能存在差异性。因此,在研究社会发展与人格间关系时,应该同时关注社会变迁的时间与空间两个维度。研究显示,随着中国社会的发展,具有开放性、多样性人格特征的新一代中国人正在形成过程中,他们反过来也会对中国的现代化进程产生影响。
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