Abstract:
Long-term survival is the priority in
treatment of patients with malignant tumors. In the field of gynecology,
fertility preservation has also recently become an important objective due to improved
treatment outcomes and different needs of patients. Methods for fertility
preservation include cervical conization, ovarian protection against radiation
or chemotherapy for ovarian cancer since the ovary is hypersensitive to cancer
therapies, treatment of gynecological cancer during pregnancy, and
cryopreservation of oocytes, embryos or ovarian tissue before treatment of malignant
tumors. Radical trachelectomy for early cervical cancer and treatment with
medroxy progesterone acetate for early endometrial carcinoma are also options
for fertility preservation, but the efficacy and risk of recurrence have yet to
be fully evaluated. The first childbirth following uterine transplantation was
also achieved last year and this success has expanded the potential for
pregnancy and delivery among cancer survivors.

Abstract:
The microscopic physical properties of Hardened Cement Paste (HCP) surfaces were evaluated by using Scanning Probe Microscopy (SPM). The cement pastes were cured under a hydrostatic pressure of 400 MPa and the contacting surfaces with a slide glass during the curing were studied. Scanning Electron Microscope (SEM) observation at a magnification of 7000 revealed smooth surfaces with no holes. The surface roughness calculated from the SPM measurement was 4 nm. The surface potential and the frictional force measured by SPM were uniform throughout the measured area 24 h after the curing. However, spots of low surface potential and stains of low frictional force and low viscoelasticity were observed one month after curing. This change was attributed to the carbonation of hydrates.

Abstract:
The recent increase in the frequency of endometrial cancer has emphasized the need for accurate diagnosis and improved treatment. The current diagnosis is still based on conventional pathological indicators, such as clinical stage, tumor differentiation, invasion depth and vascular invasion. However, the genetic mechanisms underlying endometrial cancer have gradually been determined, due to developments in molecular biology, leading to the possibility of new methods of diagnosis and treatment planning. New candidate biomarkers for endometrial cancer include those for molecular epigenetic mutations, such as microRNAs. These biomarkers may permit earlier detection of endometrial cancer and prediction of outcomes and are likely to contribute to future personalized therapy for endometrial cancer.

Reduction of ketimine with trichlorosilane was carried out using bisformamide catalyst1a derived from cyclohexanediamine to give the corresponding product in 81% yield with 39% ee. Deprotection of the formyl groups of the catalysts 1 gave the corresponding diamines 2 which were utilized in aldol reaction of acetone with 4-nitrobenzaldehyde. The reaction using 2b in brine afforded the aldol adduct in 81% yield with 29% ee.

Abstract:
Contact angle of ethylene glycol and formamide on (100) faces of NaCl, KCl, and KBr single crystal was measured, and the specific surface free energy (SSFE) was calculated. Dispersion component of the SSFE was 90.57, 93.78, and 99.52 mN·m^{-1} for NaCl, KCl, and KBr, respectively. Polar component of the SSFE was 1.05, 0.65, and 0.45 mN·m^{-1} for NaCl, KCl, and KBr. Such a large ratio of dispersion component of SSFE results from the neutrality of the crystal surface of alkali halide. Lattice component of alkali halide is 780, 717 and 689 kJ·mol^{-1} for NaCl, KCl, and KBr. The larger lattice enthalpy decreases dispersion component, and increases polar component of the SSFE. The larger lattice enthalpy is considered to enhance the rumpling of the crystal surface more strongly, and such rumpling is considered to decrease the neutrality of the crystal surface.

Abstract:
We consider a model of a quantized fermion field that is based on the Dirac equation in one dimensional space and re-examine how the fermion number of the vacuum, or the vacuum charge, varies when an external potential is switched on. With this model, fractionization of the vacuum charge has been illustrated in the literature by showing that the external potential can change the vacuum charge from zero to a fractional number. Charge conservation then appears violated in this process. This is because the charge that has been examined in this context is only a part of the total charge of the vacuum. The total charge is conserved. It is not fractionalized unless the Dirac equation has a zero mode. Two other confusing aspects are discussed. One is concerned with the usage of the continuum limit and the other with the regularization of the current operator. Implications of these aspects of the vacuum problem are explored.

Abstract:
We investigated thermal leptogenesis scenarios in the left-right symmetric extension of the standard model. In the SO(10) GUT framework, we impose the D-parity realization below GUT scale. These two conditions makes our model more restrictive and predictive. In such a case, a D-parity odd singlet in the 4-index antisymmetric tensor representation of SO(10) have a critical role. This singlet have prospects of causing a very large mass hierarchy between SU(2)L and SU(2)R triplet scalars. We test our model by computing baryogenesis via leptogenesis. The heavy right-handed neutrinos N's and the SU(2)L triplet scalar can generate the lepton number asymmetry. Leptogenesis scenarios can be categorized by these mass scales. If the light neutrinos are Majorana and have a hierarchical mass spectrum, we can obtain a successful result in leptogenesis through lightest N-decay. But we found that the normal mass hierarchy of the light neutrinos conflicts with leptogenesis through triplet-decay.

Abstract:
Functional renormalization group (FRG) is applied to the three-body scattering problem in the two-component fermionic system with an attractive contact interaction. We establish a new and correct flow equation on the basis of FRG and show that our flow equation is consistent with integral equations obtained from the Dyson-Schwinger equation. In particular, the relation of our flow equation and the Skornyakov and Ter-Martirosyan equation for the atom-dimer scattering is made clear.

Abstract:
Zero-dimensional $O(n)$-symmetric sigma models are studied by using Picard--Lefschetz integration method in the presence of small symmetry-breaking perturbations. Due to approximate symmetry, downward flows turn out to show significant structures: They slowly travel along the set of pseudo classical points, and branch into other directions so as to span middle-dimensional integration cycles. We propose an efficient way to find such slow motions for computing Lefschetz thimbles. In the limit of symmetry restoration, we figure out that only special combinations of Lefschetz thimbles can survive as convergent integration cycles: Other integrations become divergent due to non-compactness of the complexified group of symmetry. We also compute downward flows of $O(2)$-symmetric fermionic systems, and confirm that all of these properties are true also with fermions.

Abstract:
New formulation of fermionic functional renormalization group (f-FRG) with multiple regulators is proposed. It is applied to a two-component fermionic system with an attractive contact interaction in order to study the whole region of the Bardeen-Cooper-Schrieffer to Bose-Einstein condensation crossover. Combining a conventional formalism of FRG with a two-point infrared (IR) regulator and a new formalism with an IR regulator inside the four-fermion vertex, we control both one-particle fermion excitations and collective bosonic excitations. This justifies a simple approximation on the f-FRG method, so that the connection of the f-FRG formalism to the Nozi\`eres-Schmitt-Rink (NSR) theory is made clear. Aspects of f-FRG to go beyond the NSR theory are also discussed.