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Search Results: 1 - 10 of 1894 matches for " Yuya Aoki "
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Oncofertility in Gynecologic Malignant Tumors  [PDF]
Masataka Adachi, Kouji Banno, Iori Kisu, Megumi Yanokura, Moito Iijima, Takashi Takeda, Kiyoko Umene, Yuya Nogami, Eiichiro Tominaga, Daisuke Aoki
Journal of Cancer Therapy (JCT) , 2015, DOI: 10.4236/jct.2015.614128
Abstract: Long-term survival is the priority in treatment of patients with malignant tumors. In the field of gynecology, fertility preservation has also recently become an important objective due to improved treatment outcomes and different needs of patients. Methods for fertility preservation include cervical conization, ovarian protection against radiation or chemotherapy for ovarian cancer since the ovary is hypersensitive to cancer therapies, treatment of gynecological cancer during pregnancy, and cryopreservation of oocytes, embryos or ovarian tissue before treatment of malignant tumors. Radical trachelectomy for early cervical cancer and treatment with medroxy progesterone acetate for early endometrial carcinoma are also options for fertility preservation, but the efficacy and risk of recurrence have yet to be fully evaluated. The first childbirth following uterine transplantation was also achieved last year and this success has expanded the potential for pregnancy and delivery among cancer survivors.
Surface Properties of Cement Paste Evaluated by Scanning Probe Microscopy  [PDF]
Yuya Sakai
Open Journal of Civil Engineering (OJCE) , 2016, DOI: 10.4236/ojce.2016.64052
Abstract: The microscopic physical properties of Hardened Cement Paste (HCP) surfaces were evaluated by using Scanning Probe Microscopy (SPM). The cement pastes were cured under a hydrostatic pressure of 400 MPa and the contacting surfaces with a slide glass during the curing were studied. Scanning Electron Microscope (SEM) observation at a magnification of 7000 revealed smooth surfaces with no holes. The surface roughness calculated from the SPM measurement was 4 nm. The surface potential and the frictional force measured by SPM were uniform throughout the measured area 24 h after the curing. However, spots of low surface potential and stains of low frictional force and low viscoelasticity were observed one month after curing. This change was attributed to the carbonation of hydrates.
Superconducting gap structure of CeIrIn5 from field-angle-resolved measurements of its specific heat
Shunichiro Kittaka,Yuya Aoki,Toshiro Sakakibara,Akito Sakai,Satoru Nakatsuji,Yasumasa Tsutsumi,Masanori Ichioka,Kazushige Machida
Physics , 2011, DOI: 10.1103/PhysRevB.85.060505
Abstract: In order to identify the gap structure of CeIrIn5, we measured field-angle-resolved specific heat C(phi) by conically rotating the magnetic field H around the c axis at low temperatures down to 80 mK. We revealed that C(phi) exhibits a fourfold angular oscillation, whose amplitude decreases monotonically by tilting H out of the ab plane. Detailed microscopic calculations based on the quasiclassical Eilenberger equation confirm that the observed features are uniquely explained by assuming the dx2-y2-wave gap. These results strongly indicate that CeIrIn5 is a dx2-y2-wave superconductor and suggest the universal pairing mechanism in CeMIn5 (M = Co, Rh, and Ir).
Recyclable Cyclohexanediamine Derivatives as Organocatalysts: Organocatalytic Reduction with Trichlorosilane and Aldol Reaction  [PDF]
Yuya Tanimura, Kaori Ishimaru
International Journal of Organic Chemistry (IJOC) , 2013, DOI: 10.4236/ijoc.2013.34034

Reduction of ketimine with trichlorosilane was carried out using bisformamide catalyst 1a derived from cyclohexanediamine to give the corresponding product in 81% yield with 39% ee. Deprotection of the formyl groups of the catalysts 1 gave the corresponding diamines 2 which were utilized in aldol reaction of acetone with 4-nitrobenzaldehyde. The reaction using 2b in brine afforded the aldol adduct in 81% yield with 29% ee.


Dispersion and Polar Component of Specific Surface Free Energy of NaCl(100), KCl(100), and KBr(100) Single Crystal Surfaces  [PDF]
Takaomi Suzuk, Yuya Yamada
Journal of Crystallization Process and Technology (JCPT) , 2015, DOI: 10.4236/jcpt.2015.53006
Abstract: Contact angle of ethylene glycol and formamide on (100) faces of NaCl, KCl, and KBr single crystal was measured, and the specific surface free energy (SSFE) was calculated. Dispersion component of the SSFE was 90.57, 93.78, and 99.52 mN·m-1 for NaCl, KCl, and KBr, respectively. Polar component of the SSFE was 1.05, 0.65, and 0.45 mN·m-1 for NaCl, KCl, and KBr. Such a large ratio of dispersion component of SSFE results from the neutrality of the crystal surface of alkali halide. Lattice component of alkali halide is 780, 717 and 689 kJ·mol-1 for NaCl, KCl, and KBr. The larger lattice enthalpy decreases dispersion component, and increases polar component of the SSFE. The larger lattice enthalpy is considered to enhance the rumpling of the crystal surface more strongly, and such rumpling is considered to decrease the neutrality of the crystal surface.
Candidate Biomarkers for Genetic and Clinicopathological Diagnosis of Endometrial Cancer
Kouji Banno,Yuya Nogami,Iori Kisu,Megumi Yanokura,Kiyoko Umene,Kenta Masuda,Yusuke Kobayashi,Wataru Yamagami,Nobuyuki Susumu,Daisuke Aoki
International Journal of Molecular Sciences , 2013, DOI: 10.3390/ijms140612123
Abstract: The recent increase in the frequency of endometrial cancer has emphasized the need for accurate diagnosis and improved treatment. The current diagnosis is still based on conventional pathological indicators, such as clinical stage, tumor differentiation, invasion depth and vascular invasion. However, the genetic mechanisms underlying endometrial cancer have gradually been determined, due to developments in molecular biology, leading to the possibility of new methods of diagnosis and treatment planning. New candidate biomarkers for endometrial cancer include those for molecular epigenetic mutations, such as microRNAs. These biomarkers may permit earlier detection of endometrial cancer and prediction of outcomes and are likely to contribute to future personalized therapy for endometrial cancer.
Multiband superconductivity with unexpected deficiency of nodal quasiparticles in CeCu2Si2
Shunichiro Kittaka,Yuya Aoki,Yasuyuki Shimura,Toshiro Sakakibara,Silvia Seiro,Christoph Geibel,Frank Steglich,Hiroaki Ikeda,Kazushige Machida
Physics , 2013, DOI: 10.1103/PhysRevLett.112.067002
Abstract: Superconductivity in the heavy-fermion compound CeCu2Si2 is a prototypical example of Cooper pairs formed by strongly correlated electrons. For more than 30 years, it has been believed to arise from nodal d-wave pairing mediated by a magnetic glue. Here, we report a detailed study of the specific heat and magnetization at low temperatures for a high-quality single crystal. Unexpectedly, the specific-heat measurements exhibit exponential decay with a two-gap feature in its temperature dependence, along with a linear dependence as a function of magnetic field and the absence of oscillations in the field angle, reminiscent of multiband full-gap superconductivity. In addition, we find anomalous behavior at high fields, attributed to a strong Pauli paramagnetic effect. A low quasiparticle density of states at low energies with a multiband Fermi-surface topology would open a new door into electron pairing in CeCu2Si2.
Thermal leptogenesis scenarios in the predictive left-right symmetric model
Wakabayashi, Yuya
High Energy Physics - Phenomenology , 2007, DOI: 10.1143/PTP.117.1099
Abstract: We investigated thermal leptogenesis scenarios in the left-right symmetric extension of the standard model. In the SO(10) GUT framework, we impose the D-parity realization below GUT scale. These two conditions makes our model more restrictive and predictive. In such a case, a D-parity odd singlet in the 4-index antisymmetric tensor representation of SO(10) have a critical role. This singlet have prospects of causing a very large mass hierarchy between SU(2)L and SU(2)R triplet scalars. We test our model by computing baryogenesis via leptogenesis. The heavy right-handed neutrinos N's and the SU(2)L triplet scalar can generate the lepton number asymmetry. Leptogenesis scenarios can be categorized by these mass scales. If the light neutrinos are Majorana and have a hierarchical mass spectrum, we can obtain a successful result in leptogenesis through lightest N-decay. But we found that the normal mass hierarchy of the light neutrinos conflicts with leptogenesis through triplet-decay.
Flow equation of functional renormalization group for three-body scattering problems
Tanizaki, Yuya
High Energy Physics - Phenomenology , 2013,
Abstract: Functional renormalization group (FRG) is applied to the three-body scattering problem in the two-component fermionic system with an attractive contact interaction. We establish a new and correct flow equation on the basis of FRG and show that our flow equation is consistent with integral equations obtained from the Dyson-Schwinger equation. In particular, the relation of our flow equation and the Skornyakov and Ter-Martirosyan equation for the atom-dimer scattering is made clear.
Lefschetz-thimble techniques for path integral of zero-dimensional $O(n)$ sigma models
Yuya Tanizaki
Physics , 2014, DOI: 10.1103/PhysRevD.91.036002
Abstract: Zero-dimensional $O(n)$-symmetric sigma models are studied by using Picard--Lefschetz integration method in the presence of small symmetry-breaking perturbations. Due to approximate symmetry, downward flows turn out to show significant structures: They slowly travel along the set of pseudo classical points, and branch into other directions so as to span middle-dimensional integration cycles. We propose an efficient way to find such slow motions for computing Lefschetz thimbles. In the limit of symmetry restoration, we figure out that only special combinations of Lefschetz thimbles can survive as convergent integration cycles: Other integrations become divergent due to non-compactness of the complexified group of symmetry. We also compute downward flows of $O(2)$-symmetric fermionic systems, and confirm that all of these properties are true also with fermions.
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