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Search Results: 1 - 10 of 96354 matches for " Yun-Dai Chen "
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Prevalence of coronary artery ectasia in older adults and the relationship with epicardial fat volume by cardiac computed tomography angiography
Prevalence of coronary artery ectasia in older adults and relationship with epicardial fat volume by cardiac CT angiography

Jun-Jie Yang,Xia Yang,Zhi-Ye Chen,Qi Wang,Bai He,Luo-Shan Du,Yun-Dai Chen,
Jun-Jie Yang
,Xia Yang,Zhi-Ye Chen,Qi Wang,Bai He,Luo-Shan Du,Yun-Dai Chen

老年心脏病学杂志(英文版) , 2013,
Abstract: Objective Coronary artery ectasia (CAE) refers to abnormal dilation of coronary artery segments to 1.5 times of adjacent normal ones. Epicardial fat is associated with cardiovascular risk factors. The relationship between CAE and epicardial fat has not yet been investigated. This study aimed to assess the relationship between CAE and epicardial fat volume (EFV) in older people by dual-source computed tomography coronary angiography (CTCA). Methods We prospectively enrolled 1400 older adults who were scheduled for dual-source CTCA. Under reconstruction protocols, patients with abnormal segments 1.5 times larger than the adjacent segments were accepted as CAE. EFV was measured by semi-automated software. Traditional risk factors in CAE patients, as well as the extent of EFV, were analyzed and compared to non-CAE group. Results A total of 885 male and 515 female older patients were enrolled. CAE was identified by univariable analysis in 131 patients and significantly correlated to hypertension, smoking, hyperlipidemia, prior percutaneous coronary intervention and ascending aorta aneurysm. EFV was shown to be significantly higher in CAE patients than patients without ectasia. In multivariable analyses, EFV (P = 0.018), hypertension (P < 0.001) and hyperlipidemia (P < 0.001) were significantly correlated to CAE. There was a significant negative correlation between EFV and Markis classification. Conclusions CAE can be reliably recognized by dual-source CTCA. Epicardial fat might play a role in etiopathogenesis and progression of CAE, providing a new target for treating ectasia.
Research on Influencing Factors of Executive Compensation in China’s Monopoly Industries  [PDF]
Yun Dai
Open Journal of Business and Management (OJBM) , 2014, DOI: 10.4236/ojbm.2014.23026
Abstract: The annual salary income of the executives in the state-owned monopoly industry has become the focus of the society recently. With the improvement of enterprise efficiency, executives deserve to get high pay. However, it’s should be noted that because of the state-owned monopolies’ special status, business performance relies heavily on administrative monopoly power, but not actually the efforts of leaders. In this case, the income distribution mechanism is distortion, which has caused great dissatisfaction. This paper aims to study the main affecting factors of the executive compensation of state monopolies, with 1280 firm-year observations of 183 monopoly companies. We find that 1) Executive compensation is positively correlated to firm performance, firm size, CEO duality; 2) Executive compensation is negatively correlated to state share proportion and independent director proportion; 3) Company location, industry both have significant influence on executive compensation.
Synergistic effect of the combination of nanoparticulate Fe3O4 and Au with daunomycin on K562/A02 cells
Bao-An Chen,Yong-Yuan Dai,Xue-Mei Wang,Ren-Yun Zhang
International Journal of Nanomedicine , 2008,
Abstract: Bao-An Chen1, Yong-Yuan Dai1, Xue-Mei Wang2, Ren-Yun Zhang2, Wen-Lin Xu3, Hui-Ling Shen3, Feng Gao1, Qian Sun1, Xiao-Jing Deng1, Jia-hua Ding1, Chong Gao1, Yun-Yu Sun1, Jian Cheng1, Jun Wang1, Gang Zhao1, Ning-Na Chen11Department of Hematology, The Affiliated Zhongda Hospital of Southeast University, Nanjing, P.R. China; 2State Key Lab of Bioelectronics, Chien-Shiung Wu Laboratory, Southeast University, Nanjing, P.R. China; 3Department of Hematology, The Affiliated People’s Hospital, Jiangsu University, Zhenjiang, P.R. ChinaAbstract: In this study, we have explored the possibility of the combination of the high reactivity of nano Fe3O4 or Au nanoparticles and daunomycin, one of the most important antitumor drugs in the treatment of acute leukemia clinically, to inhibit MDR of K562/A02 cells. Initially, to determine whether the magnetic nanoparticle Fe3O4 and Au can facilitate the anticancer drug to reverse the resistance of cancer cells, we have explored the cytotoxic effect of daunomycin (DNR) with and without the magnetic nano-Fe3O4 or nano-Au on K562 and K562/A02 cells by MTT assay. Besides, the intracellular DNR concentration and apoptosis of the K562/A02 cells was further investigated by flow cytometry and confocal fluorescence microscopic studies. The MDR1 gene expression of the K562/A02 cells was also studied by RT-PCR method. Our results indicate that 5.0 × 10 7M nano-Fe3O4 or 2.0 × 10 8M nano-Au is biocompatible and can apparently raise the intracellular DNR accumulation of the K562/A02 cells and increase the apoptosis of tumor cells. Moreover, our observations illustrate that although these two kinds of nanoparticles themselves could not lower the MDR1 gene expression of the K562/A02 cells, yet they could degrade the MDR1 gene level when combining with anticancer drug DNR. This raises the possibility to combine the nano-Fe3O4 or nano-Au with DNR to reverse the drug resistance of K562/A02 cells, which could offer a new strategy for the promising efficient chemotherapy of the leukemia patients.Keywords: nano-Fe3O4, nano-Au, multidrug resistance, leukemia K562/A02, daunomycin
A Systematic Review of Perceived Insider Status  [PDF]
Liangtie Dai, Yuwei Chen
Journal of Human Resource and Sustainability Studies (JHRSS) , 2015, DOI: 10.4236/jhrss.2015.32010
Abstract: Perceived Insider Status (PIS) is defined as the extent to which an individual employee perceives him or herself as an insider within a particular organization. It represents that employees have earned a “personal space” and acceptance inside their work organization. Researches show that PIS has a strong effect on employee’s job performance and organizational citizenship behavior (OCB), etc. Through a review of PIS, this paper places emphasis on the elaboration of influencing factors and mechanisms of PIS from a concept perspective and tries to shed some light on not only the limitation of current researches, but also the new breakthrough points for future research.
R & D, Technology Imports and Innovation Capacity—Evidence from High-Tech Industry of China  [PDF]
Ming Dai, Yi Chen
American Journal of Industrial and Business Management (AJIBM) , 2016, DOI: 10.4236/ajibm.2016.61002
Abstract: The paper is dedicated to probing into the effects of R & D, foreign and domestic technology imports on innovation capacity by using the province-level panel data of high-tech industry from 1999 to 2012. The analysis shows that R & D, foreign technology imports do have positive influences on improving innovation capacity while the effects of domestic technology transfer are not significant and R & D do positive effects on assimilating foreign and domestic technology imports. The relationships among R & D, foreign and domestic technology and innovation capacity also take on different patterns in different regions. Technology imports’ influences on improving innovation capacity are not significant in the middle and west region. Each region should propose specific incentives for innovation to enhance regional innovation capability.
Comment on the Research Progress of the Impact of Organizational Citizenship Pressure  [PDF]
Jie Chen, Liangtie Dai
Psychology (PSYCH) , 2018, DOI: 10.4236/psych.2018.95062
Abstract: Previous studies have generally focused on the OCB, in which employees vol-untarily engage, and while because OCB is often informally encouraged or re-warded, employees may experience the pressure to become “good Staff”, that is, Organizational Citizen Pressure. This article systematically explores the formation of the concept of Organizational Citizen Pressure, the possible posi-tive and negative impacts it may have, and related research theory. The paper also looks into the future research direction of Organizational Citizen Pressure. Due to the double-edged sword effect of Organizational Citizen Pressure, a full understanding of it will be of great guidance meaning to organizational man-agement theory and practice.
Research on the Reform of the Review Method of College Professional Titles Based on Point System  [PDF]
Weihuang Dai, Xiaofang Chen
Journal of Service Science and Management (JSSM) , 2018, DOI: 10.4236/jssm.2018.114031
Abstract: Taking the confidentiality principle of professional title as the entry point, based on the existing problems of college titles, such as simple feedback mechanism, being lack of pertinence, unfairness, etc., this paper proposes a new title review method based on the point system to change the traditional system review voting method. At the same time, the review index method is introduced, and the specific operation of the case is described in detail by Analytic Hierarchy Process (AHP) and Precedence Chart (PC). It is hoped that through the reform of the review method, the openness and fairness of professional title review process will be further improved, and the incentive effect of college titles should be brought into play to promote the long-term development of colleges and teachers.
Enhancement of Recombinant Human Endostatin on the Radiosensitivity of Human Pulmonary Adenocarcinoma A549 Cells and Its Mechanism
Xiao-dong Jiang,Yun Qiao,Peng Dai,Qin Chen,Jin Wu,Da-an Song,Shi-qiu Li
Journal of Biomedicine and Biotechnology , 2012, DOI: 10.1155/2012/301931
Abstract: We observed the effects of endostar on the radiosensitivity of pulmonary adenocarcinoma A549 cells and found that endostar inhibited A549 cell growth under normoxia and hypoxia in time and dose-dependent manners; the 0 and values in control and endostar groups were (1.36 and 1.30) versus (1.019 and 1.015) under normoxia and (1.693 and 1.39) versus (2.453 and 1.026) under hypoxia, respectively; SER was 1.04 under normoxia and 1.22 under hypoxia in endostar group; under normoxia, the apoptosis rates in control, radiotherapy, endostar and combination groups were 15.9±0.57%, 42.7±0.37%, 19.9±0.48%, and 41.5±0.38%, respectively, with no significant difference between combination and radiotherapy groups; there was significant difference in G2/M phase cells between combination and radiotherapy groups (=0.028); under hypoxia, the apoptosis rates in the four groups were 16.7±0.67%, 30.1±0.95%, 26.7±0.62%, and 36.3±0.71%, respectively, with significant difference between combination and radiotherapy groups; G2/M phase cells were higher in combination group than radiotherapy group (=0.000); G2/M phase cells were higher in hypoxic combination group than in normoxic combination group (=0.003). Based on these results, we conclude that under hypoxia, endostar can enhance the radiosensitivity of A549 cells through G2/M arrest.
Mobile phone based trajectory anonymization of continuous query LBS users

CHEN Lie,FENG Yun-xia,DAI Guo-jun,

计算机应用研究 , 2011,
Abstract: To reduce the threat of user location information and personal privacy disclosure that brought by existing LBS mechanism,this paper put forward a mobile phone based location anonymization scheme for continuous query LBS users.The method used to program virtual paths with mobile device to reduce the user's privacy leakage in a continuous query,and did not need a third party server provide anonymization service.According to the presented scheme,users decided independently whether or when to start location pro...
Effect of the Velvet Antler of Formosan Sambar Deer (Cervus unicolor swinhoei) on the Prevention of an Allergic Airway Response in Mice
Ching-Yun Kuo,Ting Wang,Ting-Yeu Dai,Chih-Hua Wang,Kun-Nan Chen,Yen-Po Chen,Ming-Ju Chen
Evidence-Based Complementary and Alternative Medicine , 2012, DOI: 10.1155/2012/481318
Abstract: Two mouse models were used to assay the antiallergic effects of the velvet antler (VA) of Formosan sambar deer (Cervus unicolor swinhoei) in this study. The results using the ovalbumin- (OVA-) sensitized mouse model showed that the levels of total IgE and OVA-specific IgE were reduced after VA powder was administrated for 4 weeks. In addition, the ex vivo results indicated that the secretion of T helper cell 1 (Th1), regulatory T (Treg), and Th17 cytokines by splenocytes was significantly increased ( ) when VA powder was administered to the mice. Furthermore, OVA-allergic asthma mice that have been orally administrated with VA powder showed a strong inhibition of Th2 cytokine and proinflammatory cytokine production in bronchoalveolar fluid compared to control mice. An increase in the regulatory T-cell population of splenocytes in the allergic asthma mice after oral administration of VA was also observed. All the features of the asthmatic phenotype, including airway inflammation and the development of airway hyperresponsiveness, were reduced by treatment with VA. These findings support the hypothesis that oral feeding of VA may be an effective way of alleviating asthmatic symptoms in humans. 1. Introduction Velvet antler (VA), the unossified antler from members of the family Cervidae, has been used in traditional Chinese medicines and health foods for over 2000 years [1]. VA has been examined for various effects, including anti-inflammatory effects [2], antioxidant properties, antilipid peroxidation properties [3], and anti-infective effects [1]. Many reports and clinical observations have convincingly shown that VA and its extracts are able to alleviate the symptoms of rheumatoid arthritis [4, 5], osteoarthritis, and osteoporosis [6, 7], are able to promote dermal cell proliferation and angiogenesis [8, 9], and can be used to treat heart failure [10]. Although the detailed mechanisms of the health benefits exerted by VA have not yet been clarified, the immunoregulation effects induced by VA, such as the inhibition of the proinflammatory cytokines and T helper 1 (Th1) cells in serum and in arthritic joints [1, 5], the upregulation of monocytes, and the enhancement of the phagocytic activity [11, 12], are considered to play key roles in the health benefits. The possible bioactive components of VA that contribute to these activities have been investigated. The phosphates and gangliosides of VA are able to ease the symptoms of senility [13, 14]. Various polysaccharides and lysophosphatidylcholines have been shown to be responsible for antiulcer and
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