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Search Results: 1 - 10 of 28337 matches for " Yueming Zhu "
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Electrical conductivity measurement of serpentine at high temperature and pressure
Maoxu Zhu,Hongsen Xie,Jie Guo,Yueming Zhang,Zurning Xu
Chinese Science Bulletin , 1999, DOI: 10.1007/BF02886351
Abstract: The electrical conductivity of serpentine is measured at 1.0–3.0 GPa and 300–870°C. The effect of frequencies on electrical conductivity measurement is analyzed. The conduction mechanisms of serpentine before and after dehydration are discussed. Our experimental results show that the electrical conductivity of serpentine increases significantly after dehydration of serpentine, through which highly conductive layers (HCL) can be formed in the Earth’s interior.
Overexpression of D-psicose 3-epimerase from Clostridium cellulolyticum H10 in Bacillus subtilis and its Prospect for D-psicose Production
Xiaobo Li,Yueming Zhu,Yan Zeng,Tongcun Zhang
Advance Journal of Food Science and Technology , 2013,
Abstract: The aim of this study was to overexpress the D-psicose 3-epimerase from Clostridium cellulolyticum H10 in food-grade microbe. This gene was cloned and expressed in Bacillus subtilis The results showed that the recombinant protein was soluble, bioactive, and expressed at high levels. The optimum pH and temperature of the enzyme were 8.0 and 50°C, respectively. The activity of the enzyme was not dependent on metal ions; however, some metal ions, such as Co, make the enzyme more thermostable. The Michaelis-Menten constant (Km) of the enzyme for D-psicose was much lower than that for D-tagatose, suggesting that the optimum substrate of the enzyme is D-psicose. D-Psicose 3-epimerase expressed in the food-grade B. subtilis may be used for the industrial production of D-psicose.
Quantitative Study of Lunisolar Precession Mechanism  [PDF]
Yueming Wu, Mingfu Cao
Journal of Geoscience and Environment Protection (GEP) , 2016, DOI: 10.4236/gep.2016.47021
According to Xiaodong Song et al.’s study about difference rotation in the Earth’s inner core, a physical model of lunar motion changing the angular momentum of the Earth’s circles is presented in this work. The Lunar motion makes there be a huge gap existing in the core angular momentum between far lunar hemisphere and near lunar hemisphere. The gap results in the difference rota-tion in the Earth’s inner core, meanwhile, it increases the angular velocity of far lunar hemisphere and decreases the angular velocity of near lunar hemisphere. The Earth’s liquid outer core gene-rates an astro-geodynamical effect including the difference rotation among the Earth’s circles. It is found that when the moon moves into the apogee or the perigee of the lunar orbit, and the moon phase is the upper and lower chords (i.e. semi-diameter place), the true anomaly of the moon will change from 270-degree back (or forward) to 90-degree; this results in the mantle shell of the Earth westward, and forms lunisolar precession, the vernal equinox westward and Chandler polar motion.
Experimental studies on silicate structures of basaltic glasses quenched at 1 65093 and 1–3.5 GPa
Weiguo Zhu,Hongsen Xie,Jian Xu,Wei Hou,Yueming Zhang,Jie Guo,Zhuming Xu
Chinese Science Bulletin , 1999, DOI: 10.1007/BF02977889
Abstract: A series of melting experiments was carried cut at 1 650°C and 1.00–3.00 GPa using alkaline basalt as starting material. The cornpitions of quenched basaltic glasses in the products were detected by electron micro probe. Their CIPW norms were calculated and their refractive indices were determined by the oil-infused method. The Raman spectrum of the quenched basaltic glasses indicates that their main structural species are monomer [Si2O4]14 , chain [Si2O6]14- and sheet [Si2O5]12-. The relationship at the same temperature between the proportions of integrated areas of structural species, and compositions and pressures was discussed.

Zhu Yueming,Zhang Liaojun,Wu Yin,
,张燎军,吴 忄音

岩石力学与工程学报 , 1997,
Abstract: The fractured rock masses are considered as non homogeneous and anisotropic permeable media. The optimal fitting for calculated and measured water level and seepage discharge of measuring points is made. The reverse problem to identify the coefficient tensors of permeability of the rock masses is transformed into an equivalent mathematical minimizing problem. To improve the convergence of iterative calculation, an effective term for penalty is added to the expression of the minimum optimization function. Hereby, the solution to three dimensional complicated reverse problems can directly be obtained on computer. Finally, the solution of a complicated practical example is presented in detail.
Hexachlorophene Is a Potent KCNQ1/KCNE1 Potassium Channel Activator Which Rescues LQTs Mutants
Yueming Zheng, Xuejing Zhu, Pingzheng Zhou, Xi Lan, Haiyan Xu, Min Li, Zhaobing Gao
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0051820
Abstract: The voltage-gated KCNQ1 potassium channel is expressed in cardiac tissues, and coassembly of KCNQ1 with an auxiliary KCNE1 subunit mediates a slowly activating current that accelerates the repolarization of action potential in cardiomyocytes. Mutations of KCNQ1 genes that result in reduction or loss of channel activity cause prolongation of repolarization during action potential, thereby causing long QT syndrome (LQTs). Small molecule activators of KCNQ1/KCNE1 are useful both for understanding the mechanism of the complex activity and for developing therapeutics for LQTs. In this study we report that hexachlorophene (HCP), the active component of the topical anti-infective prescription drug pHisoHex, is a KCNQ1/KCNE1 activator. HCP potently increases the current amplitude of KCNQ1/KCNE1 expressed by stabilizing the channel in an open state with an EC50 of 4.61±1.29 μM. Further studies in cardiomyocytes showed that HCP significantly shortens the action potential duration at 1 μM. In addition, HCP is capable of rescuing the loss of function of the LQTs mutants caused by either impaired activation gating or phosphatidylinositol-4,5-bisphosphate (PIP2) binding affinity. Our results indicate HCP is a novel KCNQ1/KCNE1 activator and may be a useful tool compound for the development of LQTs therapeutics.
Krüppel-Like Factor 6 Rendered Rat Schwann Cell More Sensitive to Apoptosis via Upregulating FAS Expression
Ting Gui, Yueming Wang, Lixing Zhang, Wenjing Wang, Hao Zhu, Wenlong Ding
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0082449
Abstract: Krüppel-like factor 6 (KLF6) is a tumor suppressor gene and play a role in the regulation of cell proliferation and apoptosis. After the peripheral nerve injury (PNI), the microenvironment created by surrounding Schwann cells (SCs) is a critical determinant of its regenerative potential. In this study, we examined the effects of KLF6 on SCs responses during PNI. Both KLF6 mRNA and protein expression levels were upregulated in the injured sciatic nerve, and immunofluorescence results showed that many KLF6-positive cells simultaneously expressed the SC markers S-100 and p75NTR. The apoptosis inducers TNFα and cisplatin upregulated KLF6 expression in primary cultured SCs and the SC line RSC96. Although KLF6 overexpression exacerbated cisplatin- and TNFα-induced apoptosis, expression levels of the apoptosis regulators Bcl2 and Bax were not significantly affected in either KLF6-overexpressing or KLF6-depleted RSC96 cells. Realtime PCR arrays and qRT-PCR demonstrated that KLF6 overexpression upregulated four pro-apoptotic genes, FAS, TNF, TNFSF12, and PYCARD, and inhibited expression of the anti-apoptotic IL10 gene expression. Further analysis revealed that FAS protein expression was positively correlated with KLF6 expression in SCs. These data suggest that KLF6 upregulation may render SCs more vulnerable to apoptosis after injury via upregulating FAS expression.
Quenching effect in below-threshold high harmonic generation
Xiaosong Zhu,Xi Liu,Pengfei Lan,Qingbin Zhang,Yueming Zhou,Min Li,Peixiang Lu
Physics , 2015,
Abstract: We theoretically demonstrate the quenching effect in below-threshold high harmonic generation (HHG) by using the time-dependent density-functional theory (TDDFT). It is shown that the HHG is substantially suppressed in particular harmonic orders in the below-threshold region when multi-electron interaction comes into play. The position of the suppression is determined by the energy gap between the highest occupied orbital and the higher-lying orbital of the target. We show that the quenching effect is due to a new class of multi-electron dynamics involving electron-electron energy transfer, which is analog to the fluorescence quenching owing to the energy transfer between molecules in fluorescent material. This work reveals the important role of the multi-electron interaction on HHG especially in the below-threshold region.
Gamma-secretase: from pathogenesis to therapeutics
Li Yueming
Molecular Neurodegeneration , 2012, DOI: 10.1186/1750-1326-7-s1-l4
A Simple Analysis Method of Products lifetime Distribution
Yueming Wang
Modern Applied Science , 2009, DOI: 10.5539/mas.v3n3p38
Abstract: The basis of reliability analysis is determining products lifetime distribution type, which is also a tedious job. In accordance with the failure of parametric estimation using probability papers and hypothetical examination, products lifetime distribution type is studied with linear regression analysis and Office Excel.
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