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The effects of different potential well depths, well widths and
barrier widths on energy band of multiple quantum well (MQW) structures are
discussed in detail based on Kronig-Penny model. The results show that if the
well and barrier width stay unchanged, the first and second band gaps increase
linearly with the well depth. When the well depth is constant, the first and
second band gaps increase exponentially with the barrier width in a wide well.
However, in narrow well one, the second band gap saturates when the barrier
width is wide enough. On condition that the well and barrier have equal width,
the first band gap decreases exponentially with well-barrier width while the
second gap still shows an exponential increase with the width. These results are
insightful for the design of MQW
structure optoelectronic devices.
of silkworm pupae protein with molecular weight of less than 5000 Da were prepared
by ultrafiltration. The extracted peptide hydrolysates of silkworm pupae protein
had inhibitory action on angiotensin-I-converting enzyme activity in vitro. The hydrolysates were orally administered
to spontaneously hypertensive rats (SHR) in one period and long-term (four weeks).
The results showed that the systolic blood pressure (SBP) of the treatment groups
decreased in a dose-related manner. After one oral administration of silkworm protein
hydrolysates with doses of 60, 20 and 5 mg/kg, the SBP of SHR decreased by 21.5,
13.8, and 9.0 mmHg in 1.5 h. After four weeks of the treatment in 80 mg/kg, the
SBP decreased by 25 mmHg, with the antihypertensive activity close to 4 mg/kg of
captopril; the SBP of the 40 mg/kg dose group also decreased by 17.5 mmHg. The peptide
hydrolysate did not affect the SBP in normal, non-hypertensive rats in one period
and long-term treatments. The acute toxicity research showed that the peptide hydrolysates were safe
and without side effects. This research would be helpful in exploring the silkworm
protein peptides as functional components for the antihypertension treatment.