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Search Results: 1 - 10 of 20437 matches for " Youngbok Kim "
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SNPAnalyzer 2.0: A web-based integrated workbench for linkage disequilibrium analysis and association analysis
Jinho Yoo, Youngbok Lee, Yujung Kim, Sun Rha, Yangseok Kim
BMC Bioinformatics , 2008, DOI: 10.1186/1471-2105-9-290
Abstract: We have developed an advanced tool to perform linkage disequilibrium analysis, and genetic association analysis between disease and SNPs/haplotypes in an integrated web interface. It comprises of four main analysis modules: (i) data import and preprocessing, (ii) haplotype estimation, (iii) LD blocking and (iv) association analysis. Hardy-Weinberg Equilibrium test is implemented for each SNPs in the data preprocessing. Haplotypes are reconstructed from unphased diploid genotype data, and linkage disequilibrium between pairwise SNPs is computed and represented by D', r2 and LOD score. Tagging SNPs are determined by using the square of Pearson's correlation coefficient (r2). If genotypes from two different sample groups are available, diverse genetic association analyses are implemented using additive, codominant, dominant and recessive models. Multiple verified algorithms and statistics are implemented in parallel for the reliability of the analysis.SNPAnalyzer 2.0 performs linkage disequilibrium analysis and genetic association analysis in an integrated web interface using multiple verified algorithms and statistics. Diverse analysis methods, capability of handling huge data and visual comparison of analysis results are very comprehensive and easy-to-use.Since the completion of the HapMap project, huge numbers of individual genotypes have been generated from many kinds of laboratories. The efforts of finding or interpreting genetic association between disease and SNPs/haplotypes have been on-going widely, and the necessity of the capability to analyze huge data and diverse interpretation of the result are growing rapidly. Recently developed software programs are well suited for constructing linkage disequilibrium blocks, estimating haplotypes or detecting genetic association between disease and SNPs [1-6]. However, some software programs have drawbacks such as long computation time for the association analysis [1], limited size of dataset [1,2], inconvenient user in
A Wide Dynamics and Fast Scan Interrogating Method for a Fiber Bragg Grating Sensor Network Implemented Using Code?Division Multiple Access
Youngbok Kim,Sie-Wook Jeon,Won-Bae Kwon,Chang-Soo Park
Sensors , 2012, DOI: 10.3390/s120505888
Abstract: We propose and demonstrate a fiber Bragg grating (FBG) sensor network employing the code division multiple access (CDMA) technique to identify information from individual sensors. To detect information without considering time delays between sensors, a sliding correlation method is applied, in which two different signals with the same pseudo-random binary sequence (PRBS) pattern, but slightly different frequencies, are applied to the source and detector sides. Moreover, for time domain detection, a wavelength-to-time conversion technique using a wavelength dispersive medium is introduced. The experimental results show that the proposed sensor network has a wide strain dynamic range of 2,400 μe and a low crosstalk of 950:1.
Design of Quantification Model for Ransom Ware Prevent  [PDF]
Donghyun Kim, Seoksoo Kim
World Journal of Engineering and Technology (WJET) , 2015, DOI: 10.4236/wjet.2015.33C030

The growth of ICT within the society has become increasingly digitized, thus, the overall activity has amounted to various researches for protecting any data from malicious threats. Recently, ransomware has been a rapidly propagated subject for social engineering techniques especially the ransomware. Users can delete a ransomeware code using an antivirus software code. However, the encrypted data would be impossible to recover. Therefore, ransomware must be prevented and must have early detection before it infects any data. In this paper, we are proposing a quantification model to prevent and detect any cryptographic operations in the local drive.

Trends of Noninvasive Radiofrequency and Minimally Invasive Treatment for the Management of Facial Aging  [PDF]
Sunghee Kim, Moonjong Kim
Journal of Cosmetics, Dermatological Sciences and Applications (JCDSA) , 2019, DOI: 10.4236/jcdsa.2019.91003
Abstract: Various treatments for the management of facial aging have been performed among which noninvasive radio-frequency (RF; i.e., thermage) treatment and minimally invasive treatments are on the rise. The purpose of this study was to analyze trends of the treatment of facial aging in Korea and to investigate relationships between the use of noninvasive RF and minimally invasive treatments. A retrospective analysis conducted on data from 4021 patients showed that thermage treatment increased by 134.9% over 5 years. As a person ages, the rate of facial treatment with both the botulinum toxin (for the masseter and lines of the glabella, lateral canthus, and forehead) and the PDO thread lift increases. The use of the treatments, nasolabial fold filler and Silhouette Soft Thread, however, was not associated with aging. The patients receiving thermage treatment were less likely to undergo any of the other treatments including PDO thread lift, Silhouette Soft Thread, nasolabial fold filler, or any of the botulinum toxin treatments. Overall, the results showed that patients who had received noninvasive RF tended to receive less minimally invasive treatment.
The Effect of Prunella on Anti-Inflammatory Activity in RAW264.7 Mouse Macrophage Cells  [PDF]
Meehye Kim
Food and Nutrition Sciences (FNS) , 2012, DOI: 10.4236/fns.2012.39170
Abstract: The extracts of Prunella vulgaris L. (Labiatae), a popular Western and Chinese herbal medicine, was shown to have anti-inflammatory properties, which might be due to partially, their rosmarinic acid content. Inhition of prostaglandine E2 (PGE2) production in lipopolysaccharide (LPS) stimulated RAW264.7 mouse macrophage cells was assessed with an enzyme immunoassay (EIA) following 8-hour treatments with Prunella vulgaris extracts or fractions. Results showed that 95% ethanol extracts from P. vulgaris significantly inhibited PGE2 production. In further studies, fraction 2 from the 95% ethanol extract of P. vulgaris significantly reduced PGE2 production at 66 µg/ml (72% reduction). Cytotoxic-ity did not play a role in the noted reduction of PGE2 seen in either the extracts or fractions from P. vulgaris. High performance liquid chromatography analysis showed that there was 1.4 mM rosmarinic acid in 95% ethanol Prunella extract (201 mg/ml crude extract). Our results suggest that rosmarinic acid may contribute toward the anti-inflammatory activity of Prunella in a dose-response manner. Prunella might have a potential to be used as a functional food for anti-inflammatory activity.
An Effect of the Elastic Energy Stored in the Muscle-Tendon Complex at Two Different Coupling-Time Conditions during Vertical Jump  [PDF]
Sukwon Kim
Advances in Physical Education (APE) , 2013, DOI: 10.4236/ape.2013.31002

A study was performed to evaluate effects of elastic energy stored pre-stretch on the mechanical work output while performing vertical jump. Eight male volunteers of age between 21-29 years old participated in the present study. The present study hypothesized that the vertical jump height during countermovement jumps (CMJ) would be higher than that during squat jump (SJ). During squat jump, a volunteer paused 0.5 sec before making upward movement. The results showed that ground reaction forces and vertical jump displacements were higher in CMJ in comparison to SJ. The study concluded that part of the positive work measured did derive from the recoil of the elastic component of the muscle-tendon complex.

Material Resource Planning (MRP): Will You Need MRP without the Customer?  [PDF]
Kwahng Kim
Open Journal of Social Sciences (JSS) , 2014, DOI: 10.4236/jss.2014.24027
Abstract: The objective of this paper is to introduce a new philosophy that when integrated with existing methodologies, will improve customer service within the manufacturing sector. This paper intends to provide the reader with an understanding that the entire operation has to be involved and collectively focused in order to continuously exceed customer expectations. Short falls of existing systems will be examined with a key focus on the importance of not tying all expectations on MRP, a historical algorithmic electronic scheduling system.
A Study for Building Smart Home Environment Based on Modular Equipment Design Concept  [PDF]
Seokjin Kim
Art and Design Review (ADR) , 2015, DOI: 10.4236/adr.2015.32007
Abstract: In this paper, we propose a modular equipment design concept for building smart-home environment, which can deal with the problems such as life expectancy and complicated cable networks. Recently, the advancement of digital technology in residential networking and connections (i.e., internet cables, power cables, and network cables) has made a positive alteration to the interspatial relationship between appliances. Moreover, the interaction and communication between user and application has understood progressive changes. In future home environment, the living room is a place that has become a haven for the family and a place for entertainment as well. The downside of the new technologies is the life expectancy of the product, which is affected by a simple change to the development of digital technology.
The Impacts of Nonnative Japanese Eelgrass (Zostera japonica) on Commercial Shellfish Production in Willapa Bay, WA  [PDF]
Kim Patten
Agricultural Sciences (AS) , 2014, DOI: 10.4236/as.2014.57066

Eelgrass species worldwide are valued for the ecosystem service they provide to estuarine and marine habitats. One species, Zostera japonica, however, has some negative impacts outside its native range and is considered invasive. In Willapa Bay WA, USA, the nonnative eelgrass has expanded to the level where the shellfish industry is concerned about its potential impacts on its livelihood. Studies were conducted using paired plots, Z. japonica controlled with the herbicide imazamox vs. untreated controls, to assess the effects of Z. japonica on Manila clams (Ruditapes philippinarum) and Pacific oysters (Crassostrea gigas). Recruitment of new Manila clams was not affected by Z. japonica. The growth of young clams, total commercial clam harvests, clam quality and clam harvest efficiency, however, were greater on plots where Z. japonica was chemically controlled than where it was not treated. The response of oysters to Z. japonica control varied by site; there was no effect at one site, while the other sites had a 15% increase in shucked meat with Z. japonica control. The potential economic impact of a

Better Refined Adsorption Isotherm than BET Equation  [PDF]
Daekyoum Kim
American Journal of Analytical Chemistry (AJAC) , 2016, DOI: 10.4236/ajac.2016.75039
Abstract: During studying the heat capacity of metals and brightening more than the original Lena’s image, the temperature increasing term obtained in binomial expansion is transformed into the adsorption increasing term and thereafter we have derived the total adsorption rate equation with it. In the first layer the quantization does not occur and from 2nd layer to nth layer the quantization occurs. So as to get the total adsorption rate equation we add the quantized terms of the second to nth layers to the non-quantized term of the first layer. All terms are based on the unit surface sites. Instead of the unit surface sites, the new adsorption site term appears in the denominator of the adsorption equation. Hence the adsorption equations come out much better than BET equation. The surface area is also calculated through the integration of the adsorption isotherm equation excluding the first layer adsorption equation from the inflection point to the wanted relative pressure.
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