OALib Journal期刊

ISSN: 2333-9721



匹配条件: “Younespour Sh” ,找到相关结果约2004条。
Long term effects of a continuous and intermittent aerobic exercise on weight changes and body fat percentage in overweight and obese women
Alizadeh Z,Younespour Sh,Mansournia MA
Tehran University Medical Journal , 2013,
Abstract: Background: Obesity and sedentary lifestyle are growing problem. The global community's concern is to find the best strategy to obtain a more efficient process of weight reduction, increase physical activity, and minimize weight regain level. The purpose of this study was to evaluate the long-term effects of a short-term intervention on weight changes.Methods: The present study is a one-year follow-up study of a 12-week intervention during which the 15 individuals in the intermittent group performed 40 minutes exercise in three bouts per day; however, the 15 participants of the continuous group did the same but 40 minutes continuously. The 15 participants in the control group had no exercise prescription. After one year, weight changes, body fat percentage, and BMI were re-evaluated in the groups.Results: After adjusting the baseline weight, patterns of change in the mean weights from the end of the third month to the twelfth month were different across groups (P=0.02). After significant weight loss in the intermittent group, the mean weight in this group increased by 2.32 kilograms during the period, although not statistically significant. No increase was observed in the control group’s mean weight (P=1.00). In the continuous group, the mean weight increased statistically (P=0.048, 3.63 kilograms).Conclusion: It seems that long-term effects of moderate intensity intermittent aerobic exercise in overweight and obese women on weight control are more efficient than those of continuous exercise. However, for a change in lifestyle and prevention of weight regain, longer follow-ups are required.
The Conductivity of Indium Phosphide Irradiated by Fast Electrons  [PDF]
Sh. Sh. Rashidova
Journal of Modern Physics (JMP) , 2013, DOI: 10.4236/jmp.2013.411183

In this work, studied electrical conductivity(s) and annealing of radiation defects in crystals of n-InP are irradiated by electrons energy of 6 MeV and doses of 1017 el/cm2 (centimeter) and 2 × 1017 el/cm2 (centimeter). It is shown that alongside point defects (in the form of complexes with impurity atoms in crystals of n-InP) also form the complex defects of the type of disordered areas, annealing of which proceeds at T > 300°C that binds accumulating radiation defects.

Evaluation of Efficacy of Intense Pulsed Light (IPL) System in the Treatment of Facial Acne Vulgaris:Comparision of Different Pulse Durations; A Pilot Study
Behrooz Barikbin,Azin Ayatollahi,Shima Younespour,Somayeh Hejazi
Journal of Lasers in Medical Sciences , 2011,
Abstract: INTRODUCTION: Adequate control of acne is difficult, regardless of the various conventional modalities. Intense Pulsed Light (IPL) system is one of the emerging options that are become increasingly useful. METHODS: To achieve the best IPL parameters we evaluated the efficacy and tolerability of IPL at 752-nm wavelength, 35 j/cm2 fluence, 55-ms pulse duration in comparison with 572-nm wavelength, 35 j/cm2 fluence, 101-ms pulse duration, in a 5 week, controlled, double-blind, split-face clinical trial. Final assessment was made by comparison of the changes in inflammatory and non-inflammatory acne lesions count and the Acne Global Severity Scale (AGSS) between two groups, based on standardized photography. RESULT: Fifteen female patients, with mean age of 23.53±2.47 years (range 20-28) completed the 5-week therapy period. For both therapies, significant reductions (approximately 30%) in the comedone and inflammatory lesions count were observed (p=0.0024). There was no significant difference in the efficacy of the two treatments in reducing the percentage of comedone and inflammatory lesions count from baseline to 5th week (p=0.76 and p=0.61, respectively). Based on acne global severity scale (AGSS), no significant difference in the severity of acne lesions of the two treatments was observed at 5th-week visit (p=0.26). CONCLUSION: Considering the lack of significant difference between the two treatments and since greater risks are associated with lower pulse duration, the use of longer pulse durations is recommended, especially in darker skin phenotype. Further studies with larger number of patients are required to fully comparison of efficacy of these parameters in IPL systems for acne vulgaris.
Phenomenological and Semi-microscopic Analysis for the Elastic Scattering of Protons from 12C Nuclei at Different Energies  [PDF]
Sh. Hamada, N. Amangeldi
Journal of Modern Physics (JMP) , 2013, DOI: 10.4236/jmp.2013.45B013

Analysis of the elastic scattering of protons from 12C nuclei had been performed within the framework of both the optical model and single folding model at different proton energies; 17, 30.3, 40, 49.48 and 61.4 MeV. We have obtained the global potential parameters which could fairly reproduce the experimental data for p+12C elastic scattering at the aforementioned energies. The radial and energy dependence of the real and imaginary parts of the potential were calculated. Good agreement between experimental data and theoretical predictions in the whole angular range was obtained using both phenomenological approach (Optical Model), and semi-microscopic approach (Single Folding). In single folding calculations, the real part of the potential was calculated from a more fundamental basis by the folding method in which the NN interaction VNN(r), is folded into the density of the target nuclei and supplemented with a phenomenological imaginary potential. The obtained normalization factor Nr is in the range of 0.75 - 0.9.

Refractive Features and Diffraction Scattering Patterns Observed in the Elastic Scattering of 12C from 12C at Various Energies  [PDF]
Sh. Hamada, N. Burtebayev
Journal of Modern Physics (JMP) , 2013, DOI: 10.4236/jmp.2013.46114

We have measured the angular distributions for 12C ion beam elastically scattered from 12C target of thickness 17.4 μg/cm2 at energies 15, 18 and 21 MeV which is close to the Coulomb barrier energy for 12C + 12C nuclear system. The elastic scattering of 12C beam on 12C was analysed also at different energies (139.5, 158.8, 180, 240, 288.6, 300, 360 and 420 MeV) from literature in order to obtain the global optical potential parameters, which could fairly reproduce the experimental data. The experimental results were analysed within the framework of both the optical model and the double folding potential obtained with different density-dependent NN interactions which give the corresponding values of the nuclear incompressibility K in the Hartree-Fock calculation of nuclear matter. The agreement between the experimental results and the theoretical predictions in the whole angular range is fairly good.

A survey on the effects of three surface treatment methods on bond strength between base-metal alloys and Ceromer material (Targis)
Rokni. Sh.,Mehdizade. Sh
Journal of Dental Medicine , 2004,
Abstract: Statement of Problem: Ceramics and resins belong to the earliest tooth restorative materials. Nowadays new generations of these materials have provided a revolution in cosmetic dentistry. Ceramic Optimized polymer (Ceromer) is a newly made product that the bond between this material and base metal alloys, which are used widely today, is paid too much attention. Purpose: The aim of this study was to evaluate the bond strength of targis (Ceromer) to three types of base metal alloys through three different surface treatment methods. Materials and Methods: In this experimental study, ninety plates of Rexillium III, Silver cast and super cast alloys (30 5 0.4) were prepared and surface treated through three different methods (air oxidation, vaccum oxidation and sandblast). All samples were then veneered with 1.mm thickness of Targis. After thermocycling, three-point bending test was performed by universal testing machine (Instron) to evaluate the amount of forces at crack or fracture times in Targis. The type of failure (cohesive or adhesive) was also evaluated microscopically. Statistical analyses were made using 2-factor ANOVA and Duncan tests. Results: The type of surface treatment method caused a statistically significant difference in force rate required for crack and fracture in Targis. Sandblasting was found as the best method. The type of alloys, in all three methods, had a significant effect just on crack creation attributing the largest amount of force to Rexillium III. Adhesive type of failure occurred mostly in super-cast alloys through air-oxidation method, and cohesive type was more among silver cast alloys and sandblast method. Conclusion: According to the results of this study, bond strength between Ceromer materials and base metal alloys is significantly great and Rexillium III alloy associated with sandblast technique the best combination.
Genetics and bone disease
SH Ralston
Arthritis Research & Therapy , 2005, DOI: 10.1186/ar1519
Crizotinib: a novel and first-in-class multitargeted tyrosine kinase inhibitor for the treatment of anaplastic lymphoma kinase rearranged nonsmall cell lung cancer and beyond
Drug Design, Development and Therapy , 2011, DOI: http://dx.doi.org/10.2147/DDDT.S19045
Abstract: izotinib: a novel and first-in-class multitargeted tyrosine kinase inhibitor for the treatment of anaplastic lymphoma kinase rearranged nonsmall cell lung cancer and beyond Review (11209) Total Article Views Authors: Ou SH Published Date November 2011 Volume 2011:5 Pages 471 - 485 DOI: http://dx.doi.org/10.2147/DDDT.S19045 Sai-Hong Ignatius Ou Chao Family Comprehensive Cancer Center, University of California Irvine Medical Center, Orange, CA Abstract: Epidermal growth factor receptor (EGFR) tyrosine inhibitors were first approved for the treatment of non-small cell lung cancer (NSCLC) in 2003 in the US. Activating EGFR mutations were subsequently discovered in 2004, and heralded the era of molecular targeted therapy in NSCLC. The discovery of anaplastic lymphoma kinase (ALK) rearrangement in NSCLC in 2007 by two independent groups not only represents the first time ALK rearrangement has been discovered in common solid tumors but also represents another important milestone in the era of molecular targeted therapy in NSCLC. Crizotinib, a mesenchymal-epithelial transition (MET)/ALK multi-targeted receptor tyrosine kinase inhibitor went into early Phase I clinical development in 2007. Using the knowledge that NSCLC patients with activating EGFR mutations benefited from EGFR tyrosine kinase inhibitors, crizotinib was rapidly and successfully developed as an inhibitor in ALK-rearranged NSCLC, based on a break apart fluorescence in situ hybridization assay, developed by two of the crizotinib Phase I sites. It cumulated in the conditional approval of crizotinib by the US Food and Drug Administration on August 26, 2011 for the treatment of ALK-rearranged NSCLC. The conditional approval was based on response rates of 50% and 61% from 255 ALK-rearranged NSCLC patients enrolled in two single-arm trials. Common adverse events of crizotinib include mild transient visual disorders, mild gastrointestinal toxicities, fatigue, rare alanine transaminase elevations, and even rarer pneumonitis (1.6%). Confirmatory trials comparing crizotinib with standard chemotherapy are ongoing. It took an unprecedented four years from the discovery of ALK rearrangement in NSCLC to the approval of crizotinib, the first ever ALK inhibitor, for the treatment of ALK-rearranged NSCLC.
Reflex sympathetic dystrophy/complex regional pain syndrome, type 1
SH Botha
South African Journal of Radiology , 2004,
Nonsteroidal anti-inflammatory drug gastropathy: new avenues for safety
Roth SH
Clinical Interventions in Aging , 2011, DOI: http://dx.doi.org/10.2147/CIA.S21107
Abstract: nsteroidal anti-inflammatory drug gastropathy: new avenues for safety Review (7416) Total Article Views Authors: Roth SH Published Date May 2011 Volume 2011:6 Pages 125 - 131 DOI: http://dx.doi.org/10.2147/CIA.S21107 Sanford H Roth Arizona Research and Education, Arthritis Laboratory, Arizona State University, Phoenix, AZ, USA Abstract: Chronic oral or systemic nonselective nonsteroidal anti-inflammatory drug (NSAID) therapy, ubiquitously used by physicians to treat osteoarthritis-associated pain, is associated with a wide range of symptomatic adverse events, the most frequent and serious of which is gastropathy. Although cardiovascular and renal problems are a very real concern, they are significantly less frequent. These complications can be life-threatening in at-risk populations such as older adults, who are common users of long-term oral systemic NSAID therapy. Topical NSAID formulations deliver effective doses of analgesics directly to the affected joints, thereby limiting systemic exposure and potentially the risk of systemic adverse events, such as gastropathy and serious cardiovascular events. There are currently two topical NSAIDs approved by the US Food and Drug Administration for osteoarthritis-associated pain, as well as for the signs and symptoms of osteoarthritis. This review discusses the relative safety, and the gastrointestinal, cardiovascular, and renal risks of chronic oral or systemic NSAID therapy and topical NSAID formulations in patients with osteoarthritis.

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