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Search Results: 1 - 10 of 809 matches for " Yosuke Ozawa "
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The Clinical Application of Ambulatory Blood Pressure Monitoring in Pediatrics  [PDF]
Yosuke Miyashita
International Journal of Clinical Medicine (IJCM) , 2011, DOI: 10.4236/ijcm.2011.25111
Abstract: Management of hypertension (HTN) largely relies on proper and accurate measurement of blood pressure (BP). Even following the criteria for HTN diagnosis defined in the Fourth report on high BP in children and adolescents, inaccurate diagnosis and misdiagnosis can occur with white coat effect and masked HTN. The use of Ambulatory Blood Pressure Monitoring (ABPM) has been increasing in pediatrics in the last 20 years. The main use of ABPM is to differentiate between sustained HTN and white coat HTN in patients who have elevated casual BP measurements and to detect masked HTN in high risk patients. ABPM is most useful in patients with casual BP within 20% of the 95th percentile for age, gender, and height. This report will highlight the use of ABPM in the evaluation of elevated BP and management of HTN in pediatrics. The discussion includes a review of various non-invasive BP measuring techniques, a description of ABPM and ABPM-unique data and diagnoses, updated ABPM clinical data more specific to pediatrics, its use in HTN clinical trials, and future outlook and direction of ABPM in pediatrics.
Instability in the Hotelling’s Non-Price Spatial Competition Model  [PDF]
Yosuke Yasuda
Theoretical Economics Letters (TEL) , 2013, DOI: 10.4236/tel.2013.33A002
Abstract:

This note analyzes a slightly modified Hotelling model in which two firms are allowed to choose multiple store locations. Each firm can endogenously choose the number of stores while opening a store incurs a set-up cost. We show that the principle of minimum differentiation, i.e., both firms open a store each on the center, never holds when the set-up cost is decreasing in the number of stores. Under general cost functions that include non-linear and asymmetric set up costs, we characterize the conditions under which the principle holds. General payoff functions that are non-linear in the market share are also considered.

Characteristic Properties of Advanced Coil-External Electrodes of Fluorescent Lamps  [PDF]
Lyuji Ozawa
Journal of Materials Science and Chemical Engineering (MSCE) , 2018, DOI: 10.4236/msce.2018.62004
Abstract: The coil-EEFL lamps, which are operated with DC driving circuit, have studied. The figure of the merit of the coil-EEFL lamps is the quantum efficiency (ηq) that is given by the emitted visible photons by one moving electron in the FL lamp. The electrons in the FL lamps move on in the superconductive vacuum (R = 0) in the positive column at above room temperature, giving rise to the astronomical ηq = 1013 visible photons (m3.s)-1. Miraculously, the developed coil-EEFL lamps in the parallel connections light up with WDC = 0, without the sacrifice of the illuminance (lm.m-2). Furthermore, the scraped 40 W-HCFL lamps revitalize to the coil-EEFL lamps, promising the operation life longer than 106 hours. The shallow gap between phosphor screen and positive column can be made by side by side arrangement of the low voltage CL phosphor particles and PL phosphor particles. The coil-EEFL lamps in parallel connections may contribute to the Green Energy Projects of UN.
HCFL Lamp Only Lights Up under Coexistence of Cathode and Anode in Ar Gas Space for Half Cycle of AC Driving Circuit  [PDF]
Lyuji Ozawa
Journal of Power and Energy Engineering (JPEE) , 2019, DOI: 10.4236/jpee.2019.72001
Abstract: Vacuum space between Ar atoms in unlighted HCFL lamps is an electric insulator, because vacuum fills up with strong negative electric field from orbital electrons in 3p6 electron shell of Ar atoms. Vacuum space in lighted FL lamps changes to the neutral vacuum that provides a superconductive vacuum for moving electrons at above room temperature. The complications of lighting mechanisms of HCFL lamps for more than 80 years have clearly solved with coexistence of disparate external and internal electric circuits for each half cycle. External electric circuit acts as two roles. One helps for formation of internal electric circuit in Ar gas space by electric field. Other picks up induced voltages from capacitor CFL. HCFL lamp only lights up with moving electrons in internal DC driving circuit. Electrons in HCFL lamp only move from cathode to anode, which respectively have negative and positive potentials against grand (V = 0), and which are formed with volumes of heated corona light (4G) at around W-filament metal electrodes with a help of heated BaO particles. The HCFL lamp that emits thermoelectrons is a false story. Here we have totally revised the fundamentals of the lighting mechanism of the established HCFL lamps for last 80 years.
Protein complex prediction via verifying and reconstructing the topology of domain-domain interactions
Yosuke Ozawa, Rintaro Saito, Shigeo Fujimori, Hisashi Kashima, Masamichi Ishizaka, Hiroshi Yanagawa, Etsuko Miyamoto-Sato, Masaru Tomita
BMC Bioinformatics , 2010, DOI: 10.1186/1471-2105-11-350
Abstract: Here, we introduce a combinatorial approach for prediction of protein complexes focusing not only on determining member proteins in complexes but also on the DDI/PPI organization of the complexes. Our method analyzes complex candidates predicted by the existing methods. It searches for optimal combinations of domain-domain interactions in the candidates based on an assumption that the proteins in a candidate can form a true protein complex if each of the domains is used by a single protein interaction. This optimization problem was mathematically formulated and solved using binary integer linear programming. By using publicly available sets of yeast protein-protein interactions and domain-domain interactions, we succeeded in extracting protein complex candidates with an accuracy that is twice the average accuracy of the existing methods, MCL, MCODE, or clustering coefficient. Although the configuring parameters for each algorithm resulted in slightly improved precisions, our method always showed better precision for most values of the parameters.Our combinatorial approach can provide better accuracy for prediction of protein complexes and also enables to identify both direct PPIs and DDIs that mediate them in complexes.Recently developed high-throughput methods such as yeast two-hybrid or mass spectrometry to obtain protein-protein interactions (PPIs) have provided a global view of the interaction network [1-5]. As a PPI network grows, it becomes increasingly important to detect functional modules for understanding cellular organization and its dynamics [6]. Protein complexes are clusters of multiple proteins, and they often play a crucial part in basal cellular mechanism. Therefore, computational methods to predict protein complexes are becoming important.There are four steps in characterizing a protein complex [7]. The first step is to identify its member proteins. The second step is to determine its topology by identifying pairs of proteins which have direct inte
Economic and Environmental Effects of Installing Distributed Energy Resources into a Household  [PDF]
Akito Ozawa, Yoshikuni Yoshida
Low Carbon Economy (LCE) , 2015, DOI: 10.4236/lce.2015.62006
Abstract: Improving energy efficiency in the residential sector is a pressing issue in Japan. This study examines the economic and environmental impacts of introducing the following distributed energy resources: photovoltaics (PV), a fuel cell, and a battery. We estimate electricity and hot water demand profiles of a household by using simulated living activities. Electric power from a residential PV system is also calculated from the observed solar radiation. By using mixed integer programming, we perform a cost minimization operating simulation of a residential PV, fuel cell, and battery. The result suggests that we can create a net-zero energy house by installing both a PV system and a fuel cell into one house. On the other hand, using a battery with a fuel cell increases the household energy cost, and has few effects on CO2 emission reduction.
Relationships between Verbal and Visuospatial Working Memories and Source Monitoring among Young Children  [PDF]
Ikumi Ozawa, Ikumi Ozawa, Ikumi Ozawa, Masamichi Yuzawa, Masamichi Yuzawa, Masamichi Yuzawa
Psychology (PSYCH) , 2018, DOI: 10.4236/psych.2018.95059
Abstract: The results of previous studies examining the relationship between source monitoring and working memory in young children are not consistent. One of the reasons for this inconsistency is concerning the modalities of information with which working memory tasks deal. The present study investigated how young children’s verbal and visuospatial working memory capacity would be related to respective source-monitoring tasks with visually or verbally presented stimuli. Children aged four (n = 21) and five years (n = 21) participated in this study. They completed two verbal working memory tasks, namely, the backward digit span and listening span tests; and two visuospatial working memory tasks, namely, a comparative line test and a rotated figure test. In the source-monitoring task, first, an adult man and an adult woman read two different picture books to groups of children. Subsequently, they read short sentences aloud and showed pictures to the children. Each child then performed recognition tests for the sentences and the pictures, and required to decide on the appropriate source. Hierarchical multiple regression analyses revealed the following results: The verbal working memory task (i.e., the backward digit span) was a significant factor explaining performance on the verbal source-monitoring task, whereas the visuospatial working memory task (i.e., a rotated figure test) explained the performance on the visual source-monitoring task.
Thermal Adaptation of the Archaeal and Bacterial Lipid Membranes
Yosuke Koga
Archaea , 2012, DOI: 10.1155/2012/789652
Abstract: The physiological characteristics that distinguish archaeal and bacterial lipids, as well as those that define thermophilic lipids, are discussed from three points of view that (1) the role of the chemical stability of lipids in the heat tolerance of thermophilic organisms: (2) the relevance of the increase in the proportion of certain lipids as the growth temperature increases: (3) the lipid bilayer membrane properties that enable membranes to function at high temperatures. It is concluded that no single, chemically stable lipid by itself was responsible for the adaptation of surviving at high temperatures. Lipid membranes that function effectively require the two properties of a high permeability barrier and a liquid crystalline state. Archaeal membranes realize these two properties throughout the whole biological temperature range by means of their isoprenoid chains. Bacterial membranes meet these requirements only at or just above the phase-transition temperature, and therefore their fatty acid composition must be elaborately regulated. A recent hypothesis sketched a scenario of the evolution of lipids in which the “lipid divide” emerged concomitantly with the differentiation of archaea and bacteria. The two modes of thermal adaptation were established concurrently with the “lipid divide.”
The state of the international organ trade: a provisional picture based on integration of available information
Shimazono,Yosuke;
Bulletin of the World Health Organization , 2007, DOI: 10.1590/S0042-96862007001200017
Abstract: organ transplantation is widely practised worldwide. the expansion of organ transplantation has led to a critical shortage of organs and the development of the organ trade. many patients travel to areas where organs are obtainable through commercial transactions. although the international organ trade is regarded as an important health policy issue, its current state remains obscure because of scarce data and the lack of efforts to synthesize available data. this paper is an attempt to integrate information about the current international organ trade and create a tentative global picture based on a systematic review of 309 media reports, journal articles and other documents. the international organ trade is described in terms of its forms, the organ-exporting countries, the organ-importing countries and its outcomes and consequences.
Thermal Adaptation of the Archaeal and Bacterial Lipid Membranes
Yosuke Koga
Archaea , 2012, DOI: 10.1155/2012/789652
Abstract: The physiological characteristics that distinguish archaeal and bacterial lipids, as well as those that define thermophilic lipids, are discussed from three points of view that (1) the role of the chemical stability of lipids in the heat tolerance of thermophilic organisms: (2) the relevance of the increase in the proportion of certain lipids as the growth temperature increases: (3) the lipid bilayer membrane properties that enable membranes to function at high temperatures. It is concluded that no single, chemically stable lipid by itself was responsible for the adaptation of surviving at high temperatures. Lipid membranes that function effectively require the two properties of a high permeability barrier and a liquid crystalline state. Archaeal membranes realize these two properties throughout the whole biological temperature range by means of their isoprenoid chains. Bacterial membranes meet these requirements only at or just above the phase-transition temperature, and therefore their fatty acid composition must be elaborately regulated. A recent hypothesis sketched a scenario of the evolution of lipids in which the “lipid divide” emerged concomitantly with the differentiation of archaea and bacteria. The two modes of thermal adaptation were established concurrently with the “lipid divide.” 1. Introduction The unique structural characteristics of the archaeal polar lipids, that is, the sn-glycerol-1-phosphate (G-1-P) backbone, ether linkages, and isoprenoid hydrocarbon chains, are in striking contrast to the bacterial characteristics of the sn-glycerol-3-phosphate (G-3-P) backbone, ester linkages, and fatty acid chains. This contrast in membrane lipid structures between archaea and bacteria has been termed the “lipid divide” [1]. Because this has been repeatedly discussed [2–4], it is not discussed again here. The only thing that needs to be pointed out is that the enantiomeric difference of the lipid backbone (G-1-P and G-3-P), which is the most important feature from the evolutionary point of view, is insignificant in terms of the thermal adaptation of the membrane, because enantiomers have equivalent thermal properties. The chemical properties and physiological roles of archaeal lipids are often discussed in terms of the presence of the chemically stable ether bonds in thermophilic archaea. However, based on the archaeal lipids analyzed thus far, as shown by lipid component parts analysis [5], the mesophilic archaea possess essentially the same core lipid composition as that of the thermophilic archaea. The ether bonds therefore do not seem to be
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