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Search Results: 1 - 10 of 1627 matches for " Yoshito Hayashi "
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Choroidal and cutaneous metastasis from gastric adenocarcinoma
Shoichiro Kawai,Tsutomu Nishida,Yoshito Hayashi,Hisao Ezaki
World Journal of Gastroenterology , 2013, DOI: 10.3748/wjg.v19.i9.1485
Abstract: Choroidal or cutaneous metastasis of gastric cancer is rare. Gastrointestinal cancer was found in only 4% in patients with uveal metastasis. Choroidal metastasis from gastric cancer was reported in two cases in earlier literature. The frequency of gastric cancer as a primary lesion was 6% in cutaneous metastasis of men, and cutaneous metastasis occurs in 0.8% of all gastric cancers. We report a patient with gastric adenocarcinoma who presented with visual disorder in his left eye and skin pain on his head as his initial symptoms. These symptoms were diagnosed to be caused by choroidal and cutaneous metastasis of gastric adenocarcinoma. Two cycles of chemotherapy consisted of oral S-1 and intravenous cisplatin (SPIRITS regimen); this was markedly effective to reduce the primary gastric lesion and almost all the metastatic lesions.
Deforestation, Forest Fallowing, and Soil Conservation in Shifting Cultivation  [PDF]
Yoshito Takasaki
Theoretical Economics Letters (TEL) , 2013, DOI: 10.4236/tel.2013.35A1005

To design effective policies for rainforest conservation in shifting cultivation systems, it is crucial to have a better understanding of shifting cultivators’ decision making. This paper develops a unified dynamic farm model of shifting cultivation, addressing two lacunae in extant theoretical works: taking into account differences between primary and secondary forests and potential roles of on-farm soil conservation. The model unifies shifting cultivator’s decisions about primary-forest clearing, forest fallowing, and on-farm soil conservation by incorporating new soils acquired from cleared primary/secondary forest land into on-farm soil dynamics. I examine how three distinct policies—forest protection (e.g., protected areas), fallow management (e.g., improved fallow), and on-farm soil management (e.g., biochar in Amazonia)—alter primary-forest clearing (deforestation) and fallow length. The analysis reveals that although all three policies reduce deforestation, only on-farm soil management leads to longer fallow, i.e., sustainable secondary fallow forest.

A Comprehensive Analysis of the Response of Private Consumption to Government Spending  [PDF]
Yoshito Funashima
Theoretical Economics Letters (TEL) , 2017, DOI: 10.4236/tel.2017.77133
Abstract: This paper considers a simple model in which government spending is productive and has a complementary relationship with private consumption to study the response of the latter to government spending. We discuss how these two characteristics can yield empirical observations that indicate a positive response of private consumption to government spending. By assuming some plausible parameter settings, we demonstrate that these dual aspects of government spending, which are normally treated separately in the literature, are inseparably linked. Our findings reveal that in addition to the presence of complementarity, productivity—even if minimal—increases the likelihood of generating a positive consumption response.
Do the Bank of Japan’s Unconventional Monetary Policies Decrease Real Interest Rates under a Zero Lower Bound?  [PDF]
Yoshito Funashima
Open Journal of Social Sciences (JSS) , 2018, DOI: 10.4236/jss.2018.67010
Abstract: To test Paul Krugman’s pioneering proposal for escaping from liquidity traps, this study examines whether unconventional monetary policies under a zero lower bound decrease real interest rates in Japan. We find a sizable decline in real interest rates under zero interest rate policy and Abenomics monetary policy. In addition, we find no significant decline in real interest rates under other unconventional monetary policies, such as the first quantitative easing and comprehensive monetary easing.
Expression and Epigenetic Change of the AR and FSHR Genes in the Granulosa Cells of Endometriosis Patients
Mika Hayashi, Yoshiki Yamashita, Atsushi Hayashi, Yoko Yoshida, Sachiko Kawabe, Masami Hayashi, Yoshito Terai, Hideki Kamegai and Masahide Ohmichi
Genetics & Epigenetics , 2012, DOI: 10.4137/GEG.S9877
Abstract: Background: Endometriosis is one of the most common gynecological diseases associated with infertility. Endometriosis may affect the androgen receptor (AR) mRNA expression in human granulosa cells and the methylation of the promoter region of AR. We investigated 28 patients with endometriosis and 47 subjects without endometriosis undertaking IVF treatment. Methods: Granulosa cells were obtained from 28 patients with endometriosis and 47 subjects without endometriosis as a control. Expressions of AR and FSHR mRNA were then evaluated by OneStep real-time PCR analysis, and the level of methylation of the promoter region was qualified by methylation-specified PCR (MSP). Results: The expression of AR mRNA in the endometriosis group was statistically lower than that in the control group. As well, FSHR mRNA expression in the control group showed a positive correlation with AR mRNA expression; however, there was no such correlation in endometriosis patients. In the control group, AR mRNA expression was statistically higher in pregnant subjects compared with non-pregnant subjects; however, in the endometriosis group, no significant difference was identified. The promoter of AR was heavily methylated in all endometriosis cases; however, only 5 (45.4%) were methylated in the control group. Conclusion: Lower AR mRNA expression and methylation of the AR promoter region might affect the expression of AR and FSHR in the presence of endometriosis, thus leading to a disturbance in the regulation of AR and FSHR.
High Effective FE Simulation Methods for Deformation and Residual Stress by Butt Welding of Thin Steel Plates  [PDF]
Mikihito Hirohata, Yoshito Itoh
Engineering (ENG) , 2014, DOI: 10.4236/eng.2014.69053

In order to propose high effective simulation using finite element method (FEM) for predicting deformation and residual stress generated by one pass butt welding, a series of numerical analyses were carried out. By idealizing the movement of heat source (the instantaneous heat input method), the tendency of welding out-of-plane deformation and the residual stress distribution could be predicted. The computing time was around 9% of that by the precise model with considering the movement of heat source. On the other hand, applicability of two dimensional shell elements instead of generally used three dimensional solid elements was examined. The heat input model with considering the temperature distribution in the thickness direction was proposed for the simulation by using the shell elements. It was confirmed that the welding out-of-plane deformation and residual stress could be predicted with high accuracy by the model with shell elements and the distributed heat input methods. The computing time was around 8% of that by the precise model with solid elements.

Evaluation of Endoscopic Ultrasound Image Quality Is Necessary in Endosonographic Assessment of Early Gastric Cancer Invasion Depth
Shunsuke Yamamoto,Tsutomu Nishida,Motohiko Kato,Takuya Inoue,Yoshito Hayashi,Jumpei Kondo,Tomofumi Akasaka,Takuya Yamada,Shinichiro Shinzaki,Hideki Iijima,Masahiko Tsujii,Tetsuo Takehara
Gastroenterology Research and Practice , 2012, DOI: 10.1155/2012/194530
Abstract: We evaluated whether endoscopic ultrasonography (EUS) image quality affects the accuracy of diagnosing the vertical invasion depth of early gastric cancer (EGC). A total of 75 lesions in 75 patients suspected of having EGC were enrolled. All patients underwent EUS examination. Findings of EUS were compared with histopathologic results. We evaluated the effect of the following clinicopathologic factors: location, diameter, surface pattern, concomitant ulceration, histology type, and EUS image quality score. EUS image quality was scored based on detection repeatability, appropriate probe placement, and clarity of the five gastric wall layers including the lesion. Sixty-three lesions (84%) were pathologically mucosal and 12 lesions (16%) were submucosal cancer. Overall accuracy was 82.7%. Significantly more lesions in the upper and middle portions of the stomach were incorrectly diagnosed than in the lower portion (=0.0019). Lesion diameter was significantly larger among incorrectly diagnosed lesions (=0.0257). Low-quality images were significantly more often associated with incorrectly diagnosed lesions than with correctly diagnosed lesions (=0.0001). Multivariate analysis revealed that EUS image quality was associated with EUS staging accuracy (odds ratio, 21.8; 95% confidence interval, 4.5–137.6). Low-quality EUS images led to an incorrect diagnosis of invasion depth of EGC, independent of tumor location or size.
On Canard Homoclinic of a Liénard Perturbation System  [PDF]
Makoto Hayashi
Applied Mathematics (AM) , 2011, DOI: 10.4236/am.2011.210170
Abstract: The classification on the orbits of some Liénard perturbation system with several parameters, which is relation to the example in [1] or [2], is discussed. The conditions for the parameters in order that the system has a unique limit cycle, homoclinic orbits, canards or the unique equilibrium point is globally asymptotic stable are given. The methods in our previous papers are used for the proofs.
Development of Optophone with No Diaphragm and Application to Sound Measurement in Jet Flow
Yoshito Sonoda,Yoichi Nakazono
Advances in Acoustics and Vibration , 2012, DOI: 10.1155/2012/909437
Abstract: The optophone with no diaphragm, which can detect sound waves without disturbing flow of air and sound field, is presented as a novel sound measurement technique and the present status of development is reviewed in this paper. The method is principally based on the Fourier optics and the sound signal is obtained by detecting ultrasmall diffraction light generated from phase modulation by sounds. The principle and theory, which have been originally developed as a plasma diagnostic technique to measure electron density fluctuations in the nuclear fusion research, are briefly introduced. Based on the theoretical analysis, property and merits as a wave-optical sound detection are presented, and the fundamental experiments and results obtained so far are reviewed. It is shown that sounds from about 100?Hz to 100?kHz can be simultaneously detected by a visible laser beam, and the method is very useful to sound measurement in aeroacoustics. Finally, present main problems of the optophone for practical uses in sound and/or noise measurements and the image of technology expected in the future are shortly shown. 1. Introduction As a standard technique to measure sound waves, various types of microphone have been developed and used over one hundred years. However, they have many restrictions on practical applications, especially for sound measurement in flow of air or aeroacoustic phenomena, because they use a solid diaphragm or any vibrating object to detect sound waves. On the other hand, the light diffraction method is very effective to measure any refraction-index waves, such as high-frequency ultrasonic waves in solid or liquid, with no disturbance and has been established in the field of acoustooptics and used in many applications [1]. But the conventional light diffraction method cannot be applied to the measurement of sound waves in air with long wavelength, in which the diffracted signal light is extremely weak and also propagates in the penetrating optical beam and cannot be detected by the disturbance of the latter. The optical wave microphone (or the optophone) based on the wave optics is excellent and valuable in measuring sounds of very long wavelengths, which have not ever been treated in the conventional acoustooptics. The method is based on the theory of the Fraunhofer diffraction method, which was developed as a new means to detect the electromagnetic radiation scattered by long-wavelength plasma waves within the penetrating laser beam in the plasma nuclear fusion research [2, 3]. After that, the method has been applied to sound measurement from
Melt-Processable Nanocomposites Grafting-From Platelet Surfaces by Vapor-Assisted Surface Polymerization
Yoshito Andou,Haruo Nishida
ISRN Nanotechnology , 2011, DOI: 10.5402/2011/589615
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