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Search Results: 1 - 10 of 14248 matches for " Yingzi Yun "
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The Study on the Status and the Countermeasures of Low-carbon Financial System of China  [PDF]
Yuechun Wen, Yingzi Wu
Low Carbon Economy (LCE) , 2010, DOI: 10.4236/lce.2010.12009
Abstract: Low-carbon economy has become the inevitable choice for the future development of human society, and can not de-velop without the strong support from financing system. Based on foreign low-carbon finance development experience, through studying on the status and the existing problem of the development of the domestic low-carbon finance, it is found that it is very important to improve and perfect a low-carbon financial system for China, including the low-carbon financial institutions and products system, the low-carbon financial market system, the low-carbon finan-cial environment system and the supporting policies and measures system.
Numerical Investigation on Vortex Structure and Aerodynamic Noise Performance of Small Axial Flow Fan  [PDF]
Li Zhang, Yingzi Jin
Open Journal of Fluid Dynamics (OJFD) , 2012, DOI: 10.4236/ojfd.2012.24A046
Abstract: The details of unsteady flow field in small axial fans are described and the relationship between the internal flow char- acteristics and aerodynamic noise of small axial flow fans are explored in the manuscript. Firstly, the broadband noise model is introduced to calculate the distributions of broadband noise sources in fan’s internal flow field, and further fan’s internal flow characteristics affecting broadband noise sources are analyzed by the main distributions of broad- band noise sources. Secondly, the unsteady characteristics of vortex structure in fan’s internal flow field are analyzed by large eddy simulation, and FH-W acoustic model is introduced to calculate aerodynamic noise affected by the unsteady characteristics of vortex structure. Finally, Monitoring points are set up near and far field of small axial fans, at which sound pressure level and spectral characteristics are analyzed. The results show that broadband noise sources are mainly distributed at the tip clearance close to blade trailing edge and one third of chord length of blade trailing edge of small axial fans. The maximum sound power of broadband noise sources at the tip clearance is greater than that at blade trail- ing edge. Sound power level of broadband noise near one third of blade chord length of blade trailing edge is first in- creasing and then decreasing when the distance between radial planes and the center of fan hub increases. Fan’s internal flow characteristics affecting broadband noise sources are the tip leakage vortex and the trailing edge vortex shedding. The tip leakage vortices at the leading edge of blade tip first integrate and then break down, while vortex cores of the trailing edge vortex shedding gradually move from blade hub to one-third of blade chord
A Type 2C Protein Phosphatase FgPtc3 Is Involved in Cell Wall Integrity, Lipid Metabolism, and Virulence in Fusarium graminearum
Jinhua Jiang,Yingzi Yun,Qianqian Yang,Won-Bo Shim,Zhengyi Wang,Zhonghua Ma
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0025311
Abstract: Type 2C protein phosphatases (PP2Cs) play important roles in regulating many biological processes in eukaryotes. Currently, little is known about functions of PP2Cs in filamentous fungi. The causal agent of wheat head blight, Fusarium graminearum, contains seven putative PP2C genes, FgPTC1, -3, -5, -5R, -6, -7 and -7R. In order to investigate roles of these PP2Cs, we constructed deletion mutants for all seven PP2C genes in this study. The FgPTC3 deletion mutant (ΔFgPtc3-8) exhibited reduced aerial hyphae formation and deoxynivalenol (DON) production, but increased production of conidia. The mutant showed increased resistance to osmotic stress and cell wall-damaging agents on potato dextrose agar plates. Pathogencity assays showed that ΔFgPtc3-8 is unable to infect flowering wheat head. All of the defects were restored when ΔFgPtc3-8 was complemented with the wild-type FgPTC3 gene. Additionally, the FgPTC3 partially rescued growth defect of a yeast PTC1 deletion mutant under various stress conditions. Ultrastructural and histochemical analyses showed that conidia of ΔFgPtc3-8 contained an unusually high number of large lipid droplets. Furthermore, the mutant accumulated a higher basal level of glycerol than the wild-type progenitor. Quantitative real-time PCR assays showed that basal expression of FgOS2, FgSLT2 and FgMKK1 in the mutant was significantly higher than that in the wild-type strain. Serial analysis of gene expression in ΔFgPtc3-8 revealed that FgPTC3 is associated with various metabolic pathways. In contrast to the FgPTC3 mutant, the deletion mutants of FgPTC1, FgPTC5, FgPTC5R, FgPTC6, FgPTC7 or FgPTC7R did not show aberrant phenotypic features when grown on PDA medium or inoculated on wheat head. These results indicate FgPtc3 is the key PP2C that plays a critical role in a variety of cellular and biological functions, including cell wall integrity, lipid and secondary metabolisms, and virulence in F. graminearum.
Wnt signaling in development and disease
Yingzi Yang
Cell & Bioscience , 2012, DOI: 10.1186/2045-3701-2-14
Abstract: One of the most remarkable biological processes is the formation of a morphologically complex and functional diverse multicellular organism such as a human being from a single fertilized egg within a short period of time. During this tightly regulated process of embryonic morphogenesis, functional tissues and organs are formed and they have to be properly maintained during adult lives. Because cell-cell signaling plays essential and pivotal roles in both embryonic development and adult physiology, understanding the function and the underlying molecular mechanism of key cell signaling pathways in both development and diseases has been a major focus of our lab. Here we primarily focus on Wnt signaling in major developmental events of the skeletal system.Wnts are evolutionarily conserved major regulatory factors in both development and disease. Wnt signaling is required in most embryonic developmental processes in both invertebrates and vertebrates. Abnormal Wnt signaling causes many types of tumors [1-3]. For instance, ectopic activation of Wnt1 gene expression in the mouse mammary gland leads to tumor formation [4]. Mutations in Wnt signaling components have also been found to cause other human diseases. Weakened Wnt/β-catenin signaling leads to osteoporosis-pseudoglioma syndrome due to reduced bone mass [5] whereas enhanced Wnt/β-catenin signaling causes thick bone syndrome due to increased bone mass [6,7]. In addition, Robinow syndrome and Brachydactyly Type B1 that are characterized by shortened skeletal elements are caused by mutations in the Wnt/planar cell polarity pathway components [8-11].Wnts are a large family of secreted molecules that can signal through several distinct pathways (Figure?1). The β-catenin mediated Wnt/β-catenin pathway is also called the canonical pathway. This pathway is best understood and mainly controls cell proliferation and differentiation. Central to this pathway is the control of β-catenin stability. In the absence of Wnt signaling
Key Incorporation Scheme for Cancelable Biometrics  [PDF]
Eliza Yingzi Du, Kai Yang, Zhi Zhou
Journal of Information Security (JIS) , 2011, DOI: 10.4236/jis.2011.24018
Abstract: Biometrics is becoming an important method for human identification. However, once a biometric pattern is stolen, the user will quickly run out of alternatives and all the applications where the associated biometric pattern is used become insecure. Cancelable biometrics is a solution. However, traditional cancelable biometric methods treat the transformation process and feature extraction process independently. As a result, this kind of cancelable biometric approach would reduce the recognition accuracy. In this paper, we first analyzed the limitations of traditional cancelable biometric methods, and proposed the Key Incorporation Scheme for Cancelable Biometrics approach that could increase the recognition accuracy while achieving “cancelability”. Then we designed the Gabor Descriptor based Cancelable Iris Recognition method that is a practical implementation of the proposed Key Incorporation Scheme. The experimental results demonstrate that our proposed method can significantly improve the iris recognition accuracy while achieving “cancelability”.
In-Vitro Determination of Biological and Anabolic Functions of Weak Androgen Dehydroepiandrosterone (DHEA) Using a Variety of Cell Lines  [PDF]
James L. Cox, Yingzi Chang, Pandurangan Ramaraj
Open Journal of Endocrine and Metabolic Diseases (OJEMD) , 2015, DOI: 10.4236/ojemd.2015.58014
Abstract: Dehydroepiandrosterone (DHEA) is a weak androgen and is shown to have anti-cancer, anti-atherogenic, anti-adipogenic and anti-inflammatory effects on mouse, rat and rabbit models. However, human clinical trials data did not support animal findings and were inconclusive. These systemic differences in biological actions between rodents and humans were attributed to the low level of DHEA in rodents. In order to further understand the differences in biological functions between rodents and humans, we resorted to an in-vitroapproach involving mouse, rat and human cell lines to assess DHEA biological and anabolic functions separately and independently without systemic influence. Results indicated that DHEA was effective on mouse and rat cell lines but not on human cell lines, as observed in in-vivo studies. In addition, our in-vitrostudy showed that DHEA was able to induce myogenesis in mouse mesenchymal cells revealing its anabolic function, even though DHEA was considered as a weak androgen. This observation lent credence to the ban on DHEA by IOC medical commission, citing DHEA as an anabolic steroid. These in-vitro experiments suggested that the differences in biological actions of DHEA between rodents and humans existed not only in-vivo
Investigating Effects of Screen Layout Elements on Interface and Screen Design Aesthetics
Ahamed Altaboli,Yingzi Lin
Advances in Human-Computer Interaction , 2011, DOI: 10.1155/2011/659758
Abstract: A recent study suggested the use of the screen layout elements of balance, unity, and sequence as a part of a computational model of interface aesthetics. It is argued that these three elements are the most contributed terms in the model. In the current study, a controlled experiment was designed and conducted to systematically investigate effects of these three elements (balance, unity, and sequence) on the perceived interface aesthetics. Results showed that the three elements have significant effects on the perceived interface aesthetics. Significant interactions were also found among the three elements. A regression model relating the perceived visual aesthetics to the three elements was constructed. When validating the model using standard questionnaire scores of real web pages, high correlations were found between the values computed by the model and scores of questionnaire items related to visual layout of the web pages, indicating that layout-based measures are good at assessing the classical dimension of website aesthetics. 1. Introduction Traditionally, the focus of the field of Human Computer Interaction (HCI) is toward functionality and usability aspects in interface design. However, recently, there was a new wave in HCI field emphasizing the importance of aesthetic aspects in HCI and interface design, and in engineering research and design in general [1–3]. This shift is motivated by the increased awareness of the importance of users’ likability and aesthetic aspects in system acceptability [1]. The attention to the importance of aesthetics in interface design and its effect on users’ impressions of usability of the system began with findings of the study conducted by Kurosu and Kashimura [4]. Using different designs of an automated teller machine interface, they found high correlation between users’ prior perception of usability (they called it apparent usability) and users’ perception of visual aesthetics of the interface. Participants perceived the visually appealing interface designs as easier to use. Later, Tracinsky [5] repeated their experiment in a different context using more rigorous approaches; the same high correlation was also found in all the tested cases. Furthermore, this strong relationship between user perception of interface aesthetics and perceived usability remains intact even after actual use of the system [6]. Lindgaard et al. [7] showed that first impressions of perception of visual appeal of websites formed very quickly within 50 milliseconds. It remains stable even after considerably longer exposures [8]. Phillips
Drag-Tracking Guidance for Entry Vehicles Without Drag Rate Measurement
Han Yan,Yingzi He
Computer Science , 2014,
Abstract: A robust entry guidance law without drag rate measurement is designed for drag-tracking in this paper. The bank angle is regarded as the control variable. First, a state feedback guidance law (bank angle magnitude) that requires the drag and its rate as feedback information is designed to make the drag-tracking error be input-to-state stable (ISS) with respect to uncertainties. Then a high gain observer is utilized to estimate the drag rate which is difficult for a vehicle to measure accurately in practice. Stability analysis as well as simulation results show the efficiency of the presented approach.
A Low-Memory-Requiring and Fast Approach to Cluster Large-Scale Decoy Protein Structures  [PDF]
Yate-Ching Yuan, Yingzi Shang, Hongzhi Li
Open Journal of Biophysics (OJBIPHY) , 2012, DOI: 10.4236/ojbiphy.2012.23008
Abstract: This work demonstrates the so-called PCAC (Protein principal Component Analysis Clustering) method, which clusters large-scale decoy protein structures in protein structure prediction based on principal component analysis (PCA), is an ultra-fast and low-memory-requiring clustering method. It can be two orders of magnitude faster than the commonlyused pairwise rmsd-clustering (pRMSD) when enormous of decoys are involved. Instead of N(N – 1)/2 least-square fitting of rmsd calculations and N2 memory units to store the pairwise rmsd values in pRMSD, PCAC only requires N rmsd calculations and N × P memory storage, where N is the number of structures to be clustered and P is the number of preserved eigenvectors. Furthermore, PCAC based on the covariance Cartesian matrix generates essentially the identical result as that from the reference rmsd-clustering (rRMSD). From a test of 41 protein decoy sets, when the eigenvectors that contribute a total of 90% eigenvalues are preserved, PCAC method reproduces the results of near-native selections from rRMSD.
Transient Hydraulic Performance and Numerical Simulation of a Centrifugal Pump with an Open Impeller during Shutting Down  [PDF]
Yuliang Zhang, Zuchao Zhu, Yingzi Jin, Baoling Cui
Open Journal of Fluid Dynamics (OJFD) , 2012, DOI: 10.4236/ojfd.2012.24A044
Abstract: In this paper, the transient behavior of a low specific speed centrifugal pump with straight blades during shutting down is studied through the experimental test, theoretical calculation, and numerical simulation. The variations of the rota- tional speed, flow rate, and head with time are obtained in experiment. Based on the experimental results of the rota- tional speed and flow rate, the additional theoretical heads are quantitatively calculated and analyzed. The experimental results of the rotational speed and flow rate are worked as the boundary conditions to accurately accomplish the nu- merical simulation of the transient flow during shutting down. The experimental results show that the decrease history of the flow rate evidently lags behind that of the rotational speed, while the rotational speed slightly lags behind the head. Theoretical analysis shows that there exists a clear negative head impact phenomenon in the process of stopping. The transient behavior of the centrifugal pump with straight blades mainly comes from the rotation deceleration of im- peller, and has nothing to do with the fluid deceleration. The numerical simulations show that a large area backflow can be seen when the rotational speed decreases to zero due to the flowing inertia. In conclusion, the numerical simulation of the flow field is in good agreement with the internal flow theory of centrifugal pumps.
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