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Search Results: 1 - 10 of 530 matches for " Yildirim Imren "
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Management of Pulmonary Arterial Hypertension Secondary to Ventricular Septal Defect in Adults: Role of Combination Therapy
Imren Yildirim,Erer Dilek
The Cardiology , 2011,
Abstract: Pulmonary hypertension due to left to right shunts is a challenging problem in decision making for corrective surgery. Pre-operative cardiac data evaluation with proper medication convey better outcomes in those patients. We describe a succesful combination therapy in a paient with severe pulmonary hypertension prior , during and following ventricular septal defect closure.
Management of Pulmonary Arterial Hypertension Secondary to Ventricular Septal Defect in Adults: Role of Combination Therapy
Imren Yildirim,Erer Dilek
The Cardiology , 2006,
Abstract: Pulmonary hypertension due to left to right shunts is a challenging problem in decision making for corrective surgery. Pre-operative cardiac data evaluation with proper medication convey better outcomes in those patients. We describe a succesful combination therapy in a paient with severe pulmonary hypertension prior , during and following ventricular septal defect closure.
Prevention of Possible Embolus Following Intra Aortic Balloon Counterpulsation (IABP) Insertion by Transesophageal Echocardiography (TEE)
Irfan Tasoglu,Yildirim Imren,Levent Gokgoz
The Cardiology , 2011,
Abstract: Severe atherosclerosis of the descending aorta is directly related to atheroembolic events. Transesophageal echocardiography (TEE) is a sensitive technique for evaluating such atheroma plaques of the thoracic aorta which may predict the risk of emboli. We describe a patient with severe intraluminal aortic atherosclerotic plaques detected by TEE while positioning an Intraaortic Balloon Counterpulsation ( IABP ) during coronary artery by-pass grafting. IABP was re-positioned to prevent an emboli formation with the aid of TEE. TEE should be use to visualize descending aorta prior to IABP insertion.
Prevention of Possible Embolus Following Intra Aortic Balloon Counterpulsation (IABP) Insertion by Transesophageal Echocardiography (TEE)
Irfan Tasoglu,Yildirim Imren,Levent Gokgoz
The Cardiology , 2005,
Abstract: Severe atherosclerosis of the descending aorta is directly related to atheroembolic events. Transesophageal echocardiography (TEE) is a sensitive technique for evaluating such atheroma plaques of the thoracic aorta which may predict the risk of emboli. We describe a patient with severe intraluminal aortic atherosclerotic plaques detected by TEE while positioning an Intraaortic Balloon Counterpulsation ( IABP ) during coronary artery by-pass grafting. IABP was re-positioned to prevent an emboli formation with the aid of TEE. TEE should be use to visualize descending aorta prior to IABP insertion.
A Transesophageal Echocardiography Complication: Esophageal Diverticle Case Report
Yildirim Imren,Ersin Imren,Serhasan Bozoklu Mustafa Hakan Zor,Nuran Yener
The Cardiology , 2011,
Abstract: NA
A Transesophageal Echocardiography Complication: Esophageal Diverticle Case Report
Yildirim Imren,Ersin Imren,Serhasan Bozoklu Mustafa Hakan Zor,Nuran Yener
The Cardiology , 2005,
Abstract: NA
Complement-1 Inhibitor Attenuates Myocardial Ischemia Reperfusion Injury in a Guinea Pig Model
Yildirim Imren,Timothy P. Martens,Ariel A. Benson,Gulbin Aygencel
Research Journal of Biological Sciences , 2007,
Abstract: Complement-1 esterase inhibitor (C1-INH), an endogenously derived compound, is a key mediator providing regulation of the complement system. In this study, the protective role of C1-INH was investigated in the setting of myocardial ischemia reperfusion injury. Guinea pig hearts (n = 20) were studied in control (n = 10) and experimental (n = 10) groups, using a modified Langendorff perfusion apparatus. Control hearts were perfused with Krebs Henseleit solution during pre-ischemia and reperfusion periods while C1-INH was added to the perfusates of experimental hearts during the reperfusion period. Heart rate (pulse/minute), contractility (mm) and aortic pressure (mmHg) values were recorded at the end of pre-ischemia, post-ischemia and reperfusion periods. Perfusate and tissue analysis for glutathione and malondialdehyde levels and perfusate analysis for nitric oxide levels were obtained at the end of each experimental period. Both increased aortic pressure and cardiac contractility as well as elevated levels of tissue glutathione and MDA were observed in the experimental group during reperfusion. Perfusate levels of glutathione and MDA remained unchanged. As a result, it was concluded that C1 esterase inhibitor preserved cardiac contractility and protected against ischemia reperfusion injury.
The Relation Between Left Atrial Spontaneous Echo-Contrast (LASEC) and Homocysteine, Fibrinogen and D-Dimer Levels in Non-Valvular Atrial Fibrillation and Sinus Rythym
1Yildirim Imren MD,2Ersin Imren MD,3Emir Rusen MD,1Irfan Tasoglu MD
The Cardiology , 2005,
Abstract: Homocysteine plays an important role for thrombotic process particularly in cerebrovascular and coronary occlusive diseases. Left atrial spontaneous echo-contrast is strongly associated with left atrial thrombi and posses a significant risk for cerebrovascular ischemic events. In this study, we investigated the relations between LASEC and homocysteine, fibrinogen and D-Dimer levels in non-valvular atrial fibrillation and normal sinus ryhtym. 78 patients with cerebrovascular ischemic event were included in this study.40 patients had atrial fibrillation while the remaining had normal sinus rythym. Following clinical data collection, plasma homocysteine , fibrinogen and D-Dimer levels were evaluated. Transesophageal echocardiography was performed to all patients to detect whether occlusive event has been associated with LASEC and left atrial thrombus or not. Homocysteine levels were found higher either in atrial fibrillation and normal sinus ryhtym group with left atrial spontaneous echo-contrast group compared to non-LASEC group. In LASEC with AF and NSR group homocysteine level was found to be higher than in the patients who has non-LASEC with AF and NSR ( LASEC AF vs non-LASEC AF ; p = 0.006, LASEC AF vs non-LASEC NSR ; p = 0.001, LASEC NSR vs non – LASEC AF ; p = 0.03 , LASEC NSR vs non-LASEC NSR ; p = 0.05 ). Elevated homocystein was also observed in patients with LA thrombus in LASEC AF and NSR group ( p = 0.001 ). There was no difference in fibrinogen and D-Dimer levels among groups. High Homocysteine levels were found to be strongly associated with left atrial blood stagnation and further cerebrovascular occlusive events. The findings- although there were some limitations- prop the thrombogenic activity of high homocysteine levels.
Diagnosis and Surgical Treatment of Diaphragmatic Rupture Following Blunt Abdominal Traumas
Ahmet Karamercan,Osman Kurukahvecioglu,Yildirim Imren,Tonguc Utku Yilmaz,Mustafa Sare,Bulent Aytac
Surgery Journal , 2012,
Abstract: Diaphragmatic rupture observed in trauma patients with multiple organ injuries is a rare but serious problem. The incidence rate for diaphragmatic rupture is 0.8-5% while mortality rate is between 16.6-33.3%. There are cases in the literature which diaphragmatic rupture was diagnosed years after the trauma. Symptoms related to heart or lung compression due to early or delayed displacement of the abdominal viscera into the thorax or strangulation of abdominal viscera lead the physician to diagnosis. A 75-year old female patient who presented to the emergency room with shortness of breath, abdominal pain, nausea and vomiting complaints had been in a traffic accident 20 days earlier and admitted to the hospital. Abdominal ultrasound, plain radiographs and laboratory tests after the accident had been normal and the patient was discharged after a 24 h follow-up. Patient had signs of intestinal obstruction and abnormal blood gas values and posterior-anterior chest radiograph revealed elevation of the left hemidiaphragm. Thoracic computarized tomography demonstrated elevation of the posterolateral region of the left hemidiaphragm and displacement of the subdiaphragmatic organs within the thorax, up to the level of the carina. The patient had laparotomy under emergency conditions when rupture of the diaphragm was identified and repaired transabdominally. Diaphragmatic ruptures secondary to blunt traumas can be diagnosed with its early or late symptoms. Non-specific symptoms like chest pain, dyspnea, tachypnea, shortness of breath observed in patients should raise suspicion. Early or late deterioration in blood gas analyses following blunt traumas should be assessed carefully. Diagnosis can be rapidly established with direct radiographs, thoracic computarized tomography and magnetic resonance imaging. Treatment of rupture is surgery. Generally the diaphragm is repaired by the transabdominal approach while complicated ruptures can be assessed with a lower thoracic incision. Being extra vigilant following serious blunt traumas is an important factor in establishing the diagnosis.
Complement-1 Inhibitor Attenuates Myocardial Ischemia Reperfusion Injury in a Guinea Pig Model
Yildirim Imren,Timothy P. Martens,Ariel A. Benson,Gulbin Aygencel,Eser Oz,Mustafa Arslan,Sedat Kalaycioglu
Research Journal of Biological Sciences , 2012,
Abstract: Complement-1 esterase inhibitor (C1-INH), an endogenously derived compound, is a key mediator providing regulation of the complement system. In this study, the protective role of C1-INH was investigated in the setting of myocardial ischemia reperfusion injury. Guinea pig hearts (n = 20) were studied in control (n = 10) and experimental (n = 10) groups, using a modified Langendorff perfusion apparatus. Control hearts were perfused with Krebs Henseleit solution during pre-ischemia and reperfusion periods while C1-INH was added to the perfusates of experimental hearts during the reperfusion period. Heart rate (pulse/minute), contractility (mm) and aortic pressure (mmHg) values were recorded at the end of pre-ischemia, post-ischemia and reperfusion periods. Perfusate and tissue analysis for glutathione and malondialdehyde levels and perfusate analysis for nitric oxide levels were obtained at the end of each experimental period. Both increased aortic pressure and cardiac contractility as well as elevated levels of tissue glutathione and MDA were observed in the experimental group during reperfusion. Perfusate levels of glutathione and MDA remained unchanged. As a result, it was concluded that C1 esterase inhibitor preserved cardiac contractility and protected against ischemia reperfusion injury.
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