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Search Results: 1 - 10 of 11777 matches for " Yen-Hung Ho "
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A Case Study of Adopting Security Guidelines in Undergraduate Software Engineering Education  [PDF]
Yen-Hung Hu, Charles Scott
Journal of Computer and Communications (JCC) , 2014, DOI: 10.4236/jcc.2014.214003
Abstract: Security plays a large role in software development; simply without its existence the software would be vulnerable to many different types of attacks. Software security prevents leaks of data, alternation of data, and unauthorized access to data. Building a secure software involves a number of different processes but security awareness and implementation are the most important ones among them. To produce high quality software security engineers need to meet today’s cybersecurity demands, security awareness and implementation must be integrated in undergraduate computer science programming courses. In this paper, we demonstrate the importance of adopting security guidelines in undergraduate software engineering education. Thus, this paper focuses on integrating secure guidelines into existing applications to eliminate common security vulnerabilities. An assessment table, derived from several existing Java security guidelines, is developed to provide in depth critiques of the selected capstone project. Potential security vulnerabilities in the capstone project are identified and presented in a form showing the degree of threats against the three security characteristics: confidentiality, integrity, and availability addressed in the McCumber Cube model. Meanwhile, vulnerability density of the capstone project is calculated to demonstrate the performance of this research.
The Prognostic Value of Non-Linear Analysis of Heart Rate Variability in Patients with Congestive Heart Failure—A Pilot Study of Multiscale Entropy
Yi-Lwun Ho,Chen Lin,Yen-Hung Lin,Men-Tzung Lo
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0018699
Abstract: The influences of nonstationarity and nonlinearity on heart rate time series can be mathematically qualified or quantified by multiscale entropy (MSE). The aim of this study is to investigate the prognostic value of parameters derived from MSE in the patients with systolic heart failure.
Low-frequency Magneto-optical Spectra of Bilayer Bernal Graphene
Yen-Hung Ho,Yu-Huang Chiu,De-Hone Lin,Chen-Peng Chang,Ming-Fa Lin
Physics , 2009,
Abstract: The low-frequency magneto-optical absorption spectra of bilayer Bernal graphene are studied within the tight-binding model and gradient approximation. The interlayer interactions strongly affect the electronic properties of the Landau levels (LL's), and thus enrich the optical absorption spectra. According to the characteristics of the wave functions, the low-energy LL's can be divided into two groups. This division results in four kinds of optical absorption peaks with complex optical selection rules. Observing the experimental convergent absorption frequencies close to zero magnetic field might be useful and reliable in determining the values of several hopping integrals. The dependence of the optical absorption spectra on the field strength is investigated in detail, and the results differ considerably from those of monolayer graphene.
Optical transitions between Landau levels: AA-stacked bilayer graphene
Yen-Hung Ho,Jhao-Ying Wu,Rong-Bin Chen,Yu-Huang Chiu,Ming-Fa Lin
Physics , 2010, DOI: 10.1063/1.3488806
Abstract: The low-frequency optical excitations of AA-stacked bilayer graphene are investigated by the tight-binding model. Two groups of asymmetric LLs lead to two kinds of absorption peaks resulting from only intragroup excitations. Each absorption peak obeys a single selection rule similar to that of monolayer graphene. The excitation channel of each peak is changed as the field strength approaches a critical strength. This alteration of the excitation channel is strongly related to the setting of the Fermi level. The peculiar optical properties can be attributed to the characteristics of the LL wave functions of the two LL groups. A detailed comparison of optical properties between AA-stacked and AB-stacked bilayer graphenes is also offered. The compared results demonstrate that the optical properties are strongly dominated by the stacking symmetry. Furthermore, the presented results may be used to discriminate AABG from MG, which can be hardly done by STM.
Magneto-optical Selection Rules in Bilayer Bernal Graphene
Yen-Hung Ho,Yu-Huang Chiu,De-Hone Lin,Chen-Peng Chang,Ming-Fa Lin
Physics , 2010, DOI: 10.1021/nn9015339
Abstract: The low-frequency magneto-optical properties of bilayer Bernal graphene are studied by the tight-binding model with four most important interlayer interactions taken into account. Since the main features of the wave functions are well depicted, the Landau levels can be divided into two groups based on the characteristics of the wave functions. These Landau levels lead to four categories of absorption peaks in the optical absorption spectra. Such absorption peaks own complex optical selection rules and these rules can be reasonably explained by the characteristics of the wave functions. In addition, twin-peak structures, regular frequency-dependent absorption rates and complex field-dependent frequencies are also obtained in this work. The main features of the absorption peaks are very different from those in monolayer graphene and have their origin in the interlayer interactions.
Feature-Rich Magnetic Quantization in Sliding Bilayer Graphenes
Yao-Kung Huang,Szu-Chao Chen,Yen-Hung Ho,Chiun-Yan Lin,Ming-Fa Lin
Physics , 2014,
Abstract: The generalized tight-binding model, based on the subenvelope functions of distinct sublattices, is developed to investigate the magnetic quantization in sliding bilayer graphenes. The relative shift of two graphene layers induces a dramatic transformation between the Dirac-cone structure and the parabolic band structure, and thus leads to drastic changes of Landau levels (LLs) in the spatial symmetry, initial formation energy, intergroup anti-crossing, state degeneracy and semiconductor-metal transition. There exist three kinds of LLs, i.e., well-behaved, perturbed and unde?ned LLs, which are characterized by a speci?c mode, a main mode plus side modes, and a disordered mode, respectively. Such LLs are clearly revealed in diverse magneto-optical selection rules. Specially, the unde?ned LLs frequently exhibit intergroup anti-crossings in the ?eld-dependent energy spectra, and show a large number of absorption peaks without optical selection rules.
Protective Efficacy of VP1-Specific Neutralizing Antibody Associated with a Reduction of Viral Load and Pro-Inflammatory Cytokines in Human SCARB2-Transgenic Mice
Hsuen-Wen Chang, Yi-Wen Lin, Hui-Min Ho, Min-Han Lin, Chia-Chyi Liu, Hsiao-Yun Shao, Pele Chong, Charles Sia, Yen-Hung Chow
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0069858
Abstract: Hand-foot-mouth diseases (HFMD) caused by enterovirus 71 (EV71) and coxsackievirus 16 (CVA16) in children have now become a severe public health issue in the Asian-Pacific region. Recently we have successfully developed transgenic mice expressing human scavenger receptor class B member 2 (hSCARB2, a receptor of EV71 and CVA16) as an animal model for evaluating the pathogenesis of enterovirus infections. In this study, hSCARB2-transgenic mice were used to investigate the efficacy conferred by a previously described EV71 neutralizing antibody, N3. A single injection of N3 effectively inhibited the HFMD-like skin scurfs in mice pre-infected with clinical isolate of EV71 E59 (B4 genotype) or prevented severe limb paralysis and death in mice pre-inoculated with 5746 (C2 genotype). This protection was correlated with remarkable reduction of viral loads in the brain, spinal cord and limb muscles. Accumulated viral loads and the associated pro-inflammatory cytokines were all reduced. The protective efficacy of N3 was not observed in animals challenged with CVA16. This could be due to dissimilarity sequences of the neutralizing epitope found in CVA16. These results indicate N3 could be useful in treating severe EV71 infections and the hSCARB2-transgenic mouse could be used to evaluate the protective efficacy of potential anti-enterovirus agent candidates.
Influence of Non-Alcoholic Fatty Liver Disease on Autonomic Changes Evaluated by the Time Domain, Frequency Domain, and Symbolic Dynamics of Heart Rate Variability
Yu-Chen Liu, Chi-Sheng Hung, Yen-Wen Wu, Yi-Chin Lee, Yen-Hung Lin, Chen Lin, Men-Tzung Lo, Chun-Chieh Chan, Hsi-Pin Ma, Yi-Lwun Ho, Chien-Hung Chen
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0061803
Abstract: Background Non-alcoholic fatty liver disease (NAFLD) is associated with cardiovascular atherosclerosis independent of classical risk factors. This study investigated the influence of NAFLD on autonomic changes, which is currently unknown. Methods Subjects without an overt history of cardiovascular disease were enrolled during health checkups. The subjects diagnosed for NAFLD using ultrasonography underwent 5-min heart rate variability (HRV) measurements that was analyzed using the following indices: (1) the time domain with the standard deviation of N-N (SDNN) intervals and root mean square of successive differences between adjacent N-N intervals (rMSSD); (2) the frequency domain with low frequency (LF) and high frequency (HF) components; and (3) symbolic dynamics analysis. Routine blood biochemistry data and serum leptin levels were analyzed. Homeostasis model assessment of insulin resistance (HOMA-IR) was measured. Results Of the 497 subjects (mean age, 46.2 years), 176 (35.4%) had NAFLD. The HRV indices (Ln SDNN, Ln rMSSD, Ln LF, and Ln HF) were significantly decreased in the NAFLD group (3.51 vs 3.62 ms, 3.06 vs 3.22 ms, 5.26 vs 5.49 ms2, 4.49 vs 5.21 ms2, respectively, all P<0.05). Ln SDNN was significantly lower in the NAFLD group after adjustment for age, sex, hypertension, dyslipidemia, metabolic syndrome, body mass index, smoking, estimated glomerular filtration rate, HOMA-IR, and leptin (P<0.05). In the symbolic dynamic analysis, 0 V percentage was significantly higher in the NAFLD group (33.8% vs 28.7%, P = 0.001) and significantly correlated with linear HRV indices (Ln SDNN, Ln rMSSD, and Ln HF). Conclusions NAFLD is associated with decreased Ln SDNN and increased 0 V percentage. The former association was independent of conventional cardiovascular risk factors and serum biomarkers (insulin resistance and leptin). Further risk stratification of autonomic dysfunction with falls or cardiovascular diseases by these HRV parameters is required in patients with NAFLD.
Relationship between Bone Mineral Density and Serum Osteoprotegerin in Patients with Chronic Heart Failure
Ying-Hsien Chen, Yen-Wen Wu, Wei-Shiung Yang, Shoei-Shen Wang, Chi-Ming Lee, Nai-Kuan Chou, Ron-Bin Hsu, Yen-Hung Lin, Mao-Shin Lin, Yi-Lwun Ho, Ming-Fong Chen
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0044242
Abstract: Purpose Heart failure (HF) had been reported with increased risk of hip fractures. However, the relationship between circulating biomarkers and bone mineral density (BMD) in chronic HF remained unclear. Methods This is a cross-sectional study which recruited stable chronic HF from registry of the Heart Failure Center of National Taiwan University Hospital. Patients underwent dual-energy x-ray absorptiometry (DEXA) measurements at hip and lumbar spines and biochemical assessments including B-type natriuretic peptide (BNP-32), myostatin, follistatin and osteoprotegerin (OPG). Results A total of 115 stable chronic HF individuals with left ventricular ejection fraction (EF) <45% (74% of male, mean age at 59) were recruited with 24 patients in NYHA class I, 73 patients in NYHA class II and 18 patients in NYHA class III. Results of BMD showed that Z scores of hip in NYHA III group (?0.12±1.15) was significantly lower than who were NYHA II (0.58±1.04). Serum OPG was significantly higher in subjects of NYHA III (9.3±4.6 pmol/l) than NYHA II (7.4±2.8 pmol/l) or NYHA I (6.8±3.6 pmol/l) groups. There’s a significant negative association between log transformed serum OPG and trochanteric BMD (R = ?0.299, P = 0.001), which remained significant after multivariate analysis. Conclusions Our study demonstrated an inverse association between serum OPG and trochanteric BMD in patients with HF. OPG may be a predictor of BMD and an alternative to DEXA for identifying at risk HF patients for osteoporosis.
Molecular Dynamics Simulation of Nanoindentation-induced Mechanical Deformation and Phase Transformation in Monocrystalline Silicon
Lin Yen-Hung,Jian Sheng-Rui,Lai Yi-Shao,Yang Ping-Feng
Nanoscale Research Letters , 2008,
Abstract: This work presents the molecular dynamics approach toward mechanical deformation and phase transformation mechanisms of monocrystalline Si(100) subjected to nanoindentation. We demonstrate phase distributions during loading and unloading stages of both spherical and Berkovich nanoindentations. By searching the presence of the fifth neighboring atom within a non-bonding length, Si-III and Si-XII have been successfully distinguished from Si-I. Crystallinity of this mixed-phase was further identified by radial distribution functions.
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