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Search Results: 1 - 10 of 2907 matches for " Yen Cu "
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The Research for Exploring Product Design Characteristics by SEM via Correlated Innovation and Design Strategy  [PDF]
Yen Hsu
American Journal of Industrial and Business Management (AJIBM) , 2013, DOI: 10.4236/ajibm.2013.31002
Abstract:

Managers at NPD departments of Taiwan consumer electronic industry were interviewed to explore the effects innovation strategy (IS) has on design strategy (DS) and finally on product design characteristics (DC). The fitness of theoretical models and the observed data was examined. A questionnaire survey was conducted. 1300 enterprises in Taiwanconsumer electronic industry were randomly selected as the survey pool. At last, 370 effective questionnaires were collected. Their responses on the questionnaires were analyzed to test the fitness of the model with structural equation modeling analysis (SEM). A proper fitness was found for the correlation theoretical model of IS, DS, DC, and the observed data. In enterprises, IS will influence product DC, and at the same time, IS will influence product DC through DS. Among these three variables, DS serves as an independent variable and intervene variable to DC.

Enhanced Delivery and Potency of Self-Amplifying mRNA Vaccines by Electroporation in Situ
Yen Cu,Kate E. Broderick,Kaustuv Banerjee,Julie Hickman,Gillis Otten,Susan Barnett,Gleb Kichaev,Niranjan Y. Sardesai,Jeffrey B. Ulmer,Andrew Geall
Vaccines , 2013, DOI: 10.3390/vaccines1030367
Abstract: Nucleic acid-based vaccines such as viral vectors, plasmid DNA (pDNA), and mRNA are being developed as a means to address limitations of both live-attenuated and subunit vaccines. DNA vaccines have been shown to be potent in a wide variety of animal species and several products are now licensed for commercial veterinary but not human use. Electroporation delivery technologies have been shown to improve the generation of T and B cell responses from synthetic DNA vaccines in many animal species and now in humans. However, parallel RNA approaches have lagged due to potential issues of potency and production. Many of the obstacles to mRNA vaccine development have recently been addressed, resulting in a revival in the use of non-amplifying and self-amplifying mRNA for vaccine and gene therapy applications. In this paper, we explore the utility of EP for the in vivo delivery of large, self-amplifying mRNA, as measured by reporter gene expression and immunogenicity of genes encoding HIV envelope protein. These studies demonstrated that EP delivery of self-amplifying mRNA elicited strong and broad immune responses in mice, which were comparable to those induced by EP delivery of pDNA.
Antimicrobial activity of the autochthonous compound Enoxil  [PDF]
Lucian Lupa?cu, Valeriu Rudic, Viorica Cotos, Tudor Lupa?cu
Journal of Biomedical Science and Engineering (JBiSE) , 2010, DOI: 10.4236/jbise.2010.38101
Abstract: The paper presents data about the antimicrobial activity of the autochthonous compound of taninic source Enoxil. The minimal inhibitory and bactericidal/fungicidal concentrations were established for some skin and wound infectious agents. It was established, based on Pseudomonas bacteria model, that the Enoxil compound suppress the activity of some important enzymes—a phenomenon that leads to the increase of bacterial sensibility to many tested antibiotics.
Changing Trend in Coronary Heart Disease in Nigeria
CU Nwaneli
Afrimedic Journal , 2010,
Abstract: Background: Coronary Heart Disease (CHD) is the greatest cause of death in Western countries but reported to be rare in sub-Saharan Africa. There are suggestions that the incidence of coronary heart disease is rising in Nigeria as a result of many factors. This review looks at the burden of CHD in Nigeria and its risk factors and determines if there is a change in the trend of this disease and what might be responsible for this change. Methods: A Medline search and search of other internet search engines for published studies on CHD in Africa and Nigeria was done. The journals were sourced online and from public libraries and the publications were studied. Results: CHD is still an uncommon cardiovascular disease in Nigeria. There is a rising trend in the incidence over the last 4 decades in urban areas. The risk factors of CHD commonly found in Nigerian patients include hypertension, diabetes mellitus(DM), hyperlipidaemia, obesity, and sedentary lifestyle. Conclusion: Coronary Heart disease is still relatively uncommon in Nigeria and does not contribute significantly to morbidity and mortality from cardiovascular diseases in Nigeria. There is however substantial evidence that the incidence of CHD has increased over the last four decades. The factors responsible for this trend include, increasing prevalence of CHD risk factors, urbanization and adoption of western diet and lifestyle.
Economic analysis of swamp rice production in Ebonyi Southern Agricultural Zone of Ebonyi State, Nigeria
CU Nwaobiala
Journal of Agriculture and Social Research (JASR) , 2010,
Abstract: The aim of the paper is to analyze the determinants and profitability of the output of swamp rice farmers in Ebonyi southern Agricultural zone of Ebonyi State. Primary data were obtained through the use of structured questionnaires. A total of eighty (80) swamp rice farmers were randomly selected from the different blocks and circles of the Zone. The multiple regression analysis (Cobb- Douglas) showed that education had positive effects on the output of swamp rice at 1% level of probability. Also, household size, farm size and farming experience were statistically significant at 5% level of probability. The equation explained 71.10% of the variation in the output of swamp rice production in the study area. The results also indicate that the net profit of swamp rice cultivation per hectare was N126, 590.00. Farmers should be encouraged to engage in swamp rice cultivation by providing access to funds. Formation of cooperatives is very essential to overcome financial constraints and ban on rice importation should be enacted to encourage local rice production.
Deaths and Hospital Injuries Due to the 1999 Taiwan Earthquake  [PDF]
Yen-Hsiung Liao
Open Journal of Safety Science and Technology (OJSST) , 2012, DOI: 10.4236/ojsst.2012.24019
Abstract: To assess risk factors associated with deaths and injuries in a major earthquake area. First, we used the official data including 824 seismic deaths, 271 serious injuries, and 302 moderate injuries to elucidate and compare the demographic, structural, and injury characteristics among the three groups. Secondly, a population based case-control study was conducted to examine how structural factors, medical assistance, personal characteristic, and behavior and preparedness contributed to injury. The age-specific proportions of the three groups were similar and higher in the elderly population. Severity of injuries was proportional to the proportion of completely collapsed houses. Fracture was the most frequently observed among the serious injuries and moderate injuries. Head injury was the major body site caused by the collapsed houses for the seismic deaths. In a case-control study, people who were trapped (adjusted OR = 12.31, 95% CI: 6.29 - 24.28) had the greatest risk of serious injuries, followed by those who were illiterate, in completely collapsed houses, and experienced unprepared flares. This study reveals that improvement in anti-seismic construction, head protect, and literacy education could decrease the effect of disaster. Further, using a flashlight to see in the dark, and moving slowly rather than running should be rigorously recommended as common-sense responses.
Health problems in the temporary housing in Taiwan  [PDF]
Yen-Hsiung Liao
Health (Health) , 2013, DOI: 10.4236/health.2013.54088
Abstract:

To understand the health effects of the temporary housing after the September 1999 earthquake in Taiwan, we conducted the object observation, environmental monitoring, questionnaire survey, and disease analysis in both spring and autumn seasons to rate the presence and magnitude of exposures of environmental hazards. In the hot season more people identified poor ventilation, dampness, hot, odor, and insecurity as sources of hazards. The health effects on the cervix and vagina, liver, and respiratory disease assessed by clinic visits were corresponded to the environmental exposures, and complaints. It was suggested that reducing the risks to temporary housing residences by means of improving housing ventilation and providing community security when the permanent housing was not finished from the experience of Chi-Chi earthquake disaster in Taiwan.


An Investigation of Social Factors in Children’s Foreign Language Learning—A Case Study of Taiwanese Elementary School Students  [PDF]
Yen-Ju Hou
Open Journal of Modern Linguistics (OJML) , 2015, DOI: 10.4236/ojml.2015.52010
Abstract: Social factors are believed to play a crucial role in language learning and have a major impact on second/foreign language proficiency (Ellis, 2003). The study was conducted to investigate Taiwanese children’s English learning motivation/attitude and the impacts of social factors of age, gender and social class on their English learning. Participants were 520 students from 6 elementary schools near Tainan City, divided into two groups as Urban Group (N = 271) and Rural Group (N = 249) based on their schools’ location. All were arranged to fill out a questionnaire dealing with their background and English learning motivation/attitude (Gardner, 1985). All available data were processed by SPSS 17.0 for descriptive, correlation, ANOVA, and predictive analyses. It was expected that the findings could provide more understanding about how social factors affect children’s second/foreign language learning, and to unlock the potential of the rural students when it comes to the tenth year of the official implementation of English teaching in Taiwanese elementary schools.
The Development of an Alternative Method for the Sovereign Credit Rating System Based on Adaptive Neuro-Fuzzy Inference System  [PDF]
Hakan Pabu?cu, Tuba Yak?c? Ayan
American Journal of Operations Research (AJOR) , 2017, DOI: 10.4236/ajor.2017.71003
Abstract: The main purpose of this article is to determine the factors affecting credit rating and to develop the credit rating system based on statistical methods, fuzzy logic and artificial neural network. Variables used in this study were determined by the literature review and then the number of them was reduced by using stepwise regression analysis. Resulting variables were used as independent variables in the logistic model and as input variables for ANN and ANFIS model. After evaluating the models and comparing with each other, the ANFIS model was chosen as the best model to forecast credit rating. Rating determination was made for the countries that haven’t had a credit rating. Consequently, the ANFIS model made consistent, reliable and successful rating forecasts for the countries.
Outcome of Cataract Surgery in Patients Treated for Retinopathy of Prematurity  [PDF]
Huy Nguyen, Kimberly G. Yen
Open Journal of Ophthalmology (OJOph) , 2017, DOI: 10.4236/ojoph.2017.74038
Abstract:
Background/Aims: Pediatric patients with treated retinopathy of prematurity (ROP) may develop visually significant cataracts. We report the outcome of cataract surgery in patients who had ROP treatment. Method: Retrospective chart review of 19 eyes from 16 patients who had ROP treatment and subsequent cataract surgery between August, 2002 and March, 2015. Results: Eighteen of 19 eyes received laser treatment for ROP; 1 eye received intravitreal bevacizumab. 5 eyes received lens-sparing pars plana vitrectomy (LSPPV) in addition to laser. Average follow up was 10.1 ± 5.5 years. Average visual acuity improved from 20/324 prior to and 20/110 after cataract surgery (p = 0.06). 13/19 (68%) of the eyes received laser only and developed cataracts an average of 6.2 ± 5.6 years after laser treatment. 5/19 (26%) eyes developed cataracts an average of 6.4 ± 4.2 years after LSPPV and laser. In one eye, a cataract developed after a bevacizumab injection 2.9 years after the injection. Visual axis opacification (VAO) developed in 2/5 (40%) eyes after Ce/PCIOL/PPC-Antvx, 8/10 eyes (80%) after CE/IOL, and in 0/4 eyes after CE/PPC-AntVx. Ocular comorbidities included strabismus, nystagmus, amblyopia, optic atrophy, corneal band keratopathy, and phthisis bulbi. Conclusion: Cataract surgery in patients who have a history of ROP can be complicated by anatomical changes from prematurity and prior vitreoretinal surgeries. Vision improvement is limited by other ocular comorbidities.
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