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Search Results: 1 - 10 of 10013 matches for " Yanfang Rui "
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Study on the Risk Evaluation of Government Purchasing Public Service Based on Matter Element Extension Model  [PDF]
Yanfang Chen
Open Journal of Social Sciences (JSS) , 2018, DOI: 10.4236/jss.2018.62012
The government purchase public service has the dual effect of performance and risk, and risk management should run through the purchase service. By identifying the key influencing factors, this paper constructs the risk evaluation index system of government purchasing public services, and introduces the matter element extension method to quantify all kinds of risks. The empirical test is based on the sample data of S province. The results show that the risk level of government purchase of public service is “high” and the trend of “medium” level is obvious. The institutional arrangement leads to a “higher” social risk, management risk and economic risk. It is mainly related to the factors such as voluntary failure, internal effect, social trust, power capital, information disclosure, rules and regulations, and management process. Based on this, this paper puts forward the corresponding policy recommendations.
Does Education Improve Intergenerational Income Mobility?  [PDF]
Yanfang Liao
Open Journal of Social Sciences (JSS) , 2019, DOI: 10.4236/jss.2019.75006
Abstract: When the whole people enter a well-off society, the income gap between residents and the solidification of social strata remain the focus of government and society. The improvement of intergenerational income mobility can improve the internal structure of income distribution and promote social stratum mobility to a certain extent. As the saying goes, “knowledge changes fate”, but there are also “poor families can hardly give birth to noble children”. Then, whether the improvement of education level can help individuals to move upwards, weaken the influence of family economic status on their income, and improve intergenerational mobility? This paper uses household income distribution survey, estimates intergenerational income elasticity with double samples, and uses Intersection item to analyze the effect of education level on intergenerational income elasticity in the model. The empirical results show that the increase of educational years can improve intergenerational income mobility, and the effect is better in rural areas. Therefore, the government should promote education fairness, protect children’s equal right to education, especially low-income families, guide them in the concept of education, continue the development of compulsory education, and improve the funding system of higher education.
Dynamic Shortest Path Algorithm in Stochastic Traffic Networks Using PSO Based on Fluid Neural Network  [PDF]
Yanfang Deng, Hengqing Tong
Journal of Intelligent Learning Systems and Applications (JILSA) , 2011, DOI: 10.4236/jilsa.2011.31002
Abstract: The shortest path planning issure is critical for dynamic traffic assignment and route guidance in intelligent transportation systems. In this paper, a Particle Swarm Optimization (PSO) algorithm with priority-based encoding scheme based on fluid neural network (FNN) to search for the shortest path in stochastic traffic networks is introduced. The proposed algorithm overcomes the weight coefficient symmetry restrictions of the traditional FNN and disadvantage of easily getting into a local optimum for PSO. Simulation experiments have been carried out on different traffic network topologies consisting of 15-65 nodes and the results showed that the proposed approach can find the optimal path and closer sub-optimal paths with good success ratio. At the same time, the algorithms greatly improve the convergence efficiency of fluid neuron network.
Inhibition of AMPA receptor trafficking at hippocampal synapses by β-amyloid oligomers: the mitochondrial contribution
Yanfang Rui, Jiaping Gu, Kuai Yu, H Criss Hartzell, James Q Zheng
Molecular Brain , 2010, DOI: 10.1186/1756-6606-3-10
Abstract: We found that a brief exposure of hippocampal neurons to Aβ oligomers not only led to marked removal of AMPARs from postsynaptic surface but also impaired rapid AMPAR insertion during chemically-induced synaptic potentiation. We also found that Aβ oligomers exerted acute impairment of fast mitochondrial transport, as well as mitochondrial translocation into dendritic spines in response to repetitive membrane depolarization. Quantitative analyses at the single spine level showed a positive correlation between spine-mitochondria association and the surface accumulation of AMPARs. In particular, we found that spines associated with mitochondria tended to be more resistant to Aβ inhibition on AMPAR trafficking. Finally, we showed that inhibition of GSK3β alleviated Aβ impairment of mitochondrial transport, and effectively abolished Aβ-induced AMPAR loss and inhibition of AMPAR insertion at spines during cLTP.Our findings indicate that mitochondrial association with dendritic spines may play an important role in supporting AMPAR presence on or trafficking to the postsynaptic membrane. Aβ disruption of mitochondrial trafficking could contribute to AMPAR removal and trafficking defects leading to synaptic inhibition.Alzheimer's disease (AD) often attacks aged populations and is highlighted by progressive loss of memory and cognitive abilities [4]. AD brains exhibit two major pathological hallmarks: extracellular senile plaques containing β-amyloid aggregates and intracellular neurofibrillary tangles consisting of hyperphosphorylated microtubule-associated tau proteins [5,6]. β-amyloid (Aβ) molecules are generated by proteolytic cleavage of the transmembrane β-amyloid precursor protein (APP) [7,8]. Aggregated Aβ fibrils constitute the core of neuritic plaques and are believed to be a major culprit for neurodegeneration and subsequent cognitive abnormalities in AD patients [9-11]. Recent studies, however, indicate that Aβ molecules exert adverse effects on neuronal functions
Epidemiology of Functional Abdominal Bloating and Its Impact on Health Related Quality of Life: Male-Female Stratified Propensity Score Analysis in a Population Based Survey in Mainland China
Meijing Wu, Yanfang Zhao, Rui Wang, Wenxin Zheng, Xiaojing Guo, Shunquan Wu, Xiuqiang Ma, Jia He
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0102320
Abstract: Background The epidemiology of Functional abdominal bloating (FAB) and its impact on health-related quality of life (HRQoL) in Chinese people remains unclear. Methods Randomised, stratified, multi-stage sampling methodology was used to select a representative sample of the general population from five cities in China (n = 16,078). All respondents completed the modified Rome II questionnaire; 20% were asked to complete the 36-item Short Form (SF-36). The associated factors of FAB were analyzed. The effects of FAB on HRQoL were estimated with gender stratification using propensity score techniques in 20% subsample. Results Overall, 643 individuals (4.00%) had FAB and it was more prevalent in males than in females (4.87% vs. 3.04%, P<0.001). For males, self-reported history of dyspepsia was most strongly associated with FAB (OR = 2.78; 95% CI: 1.59, 4.72). However, the most strongly associated factor was self-reported health status for females (moderate health vs. good health: OR = 2.06, 95% CI: 1.07, 3.96. P = 0.030; poor health vs. good health: OR = 5.71, 95% CI: 2.06, 15.09). Concerning HRQoL, FAB was found to be related to two domains: role limitation due to physical problems (P = 0.030) and bodily pain (P<0.001) in females. While, in males, there were significant differences in multiple domains between those with and without FAB. Conclusion The prevalence of FAB in China was lower than previous reports. Males who had ever been diagnosed with dyspepsia and females who were in a poor self-reported health status were correlated with a higher prevalence of FAB. FAB affected only physical health in females, but impaired both physical and mental health in males.
A Tentative Study of How to Improve the Effectiveness of Classroom Interaction
Yanfang LU
Studies in Literature and Language , 2011, DOI: 10.3968/j.sll.1923156320110203.011
Abstract: The effectiveness of English learning and teaching is the ultimate goal of English education. Yet in China, English teaching is far from being effective. There is a lack of effective interaction between teacher and students in class. Using the framework of Conversation Analysis, this thesis summarizes four most frequently used classroom interaction models and their characteristics. Then it proposes some strategies on how to improve classroom interaction, they are: Clarification Requests, Confirmation Checks, Comprehension Checks, Conversational Adjustments, Partial, Exact, Expanded, and Total Self-Repetition, Partial, Complete, Expanded, and Total Other-Repetition. Key words: Effectiveness; English teaching; Conversation Analysis
Research on Cost Strategies in Railway Construction Business Based on Value Chain Analysis
Yanfang WU
Management Science and Engineering , 2012, DOI: 10.3968/j.mse.1913035x20120603.2699
Abstract: Based on the completive advantage and value chain, this paper analyzes the key link of value chain construction and value creation of railway construction enterprises, after this, we discussed the effective approaches and methods for railway construction enterprises to carry out cost strategy and promote the market development. Key word: Railway construction enterprises; Value chain; Cost strategies
Health related quality of life measured by SF-36: a population-based study in Shanghai, China
Rui Wang, Cheng Wu, Yanfang Zhao, Xiaoyan Yan, Xiuqiang Ma, Meijing Wu, Wenbin Liu, Zheng Gu, June Zhao, Jia He
BMC Public Health , 2008, DOI: 10.1186/1471-2458-8-292
Abstract: A total of 1034 subjects were randomly sampled using a stratified multiple-stage sampling method in Shanghai. Demographic information was collected, and SF-36 was used to measure HRQL.Internal reliability coefficients were greater than 0.7 in six of the eight SF-36 dimensions, except social function and mental health. Intraclass correlation coefficients ranged from 0.689 to 0.972. Split-half reliability coefficients were higher than 0.9 in five SF-36 dimensions. Validity was assessed by factor analysis and correlation analysis. Our results were basically in accordance with the theoretical construction of SF-36. The average scores of most SF-36 dimensions were higher than 80. The primary influencing risk factors of HRQL included chronic diseases, age, frequency of activities, and geographical region, which were identified using multivariate stepwise regression.Overall, HRQL in the population of Shanghai is quite good. The Mandarin version of SF-36 is a valid and reliable tool for assessing HRQL.Conception of health has been changed with the development of medicine and medical sciences since 1970's. Health is defined as a dynamic state of human wellbeing characterized by a physical, mental, and social potential which satisfies the demands of a life corresponding to age, culture, and personal responsibility, and not merely the absence of disease or infirmity. Health related quality of life (HRQL) is an individual's satisfaction or happiness with the dimensions of life insofar as they affect or are affected by "health" as defined above. HRQL has been introduced to assess people's health status. To date, a number of questionnaires have been developed to evaluate HRQL, and the 36-item Short Form Health Survey (SF-36) is the most commonly used one.SF-36 was developed from the Medical Outcomes Study or RAND Health Insurance Experiment [1]. It is a short-form derived from a larger 149-item instrument and is more precise than its predecessor, SF-20 [2]. SF-36 has been proven
A Novel Statistical Prognostic Score Model That Includes Serum CXCL5 Levels and Clinical Classification Predicts Risk of Disease Progression and Survival of Nasopharyngeal Carcinoma Patients
Haibo Zhang, Weixiong Xia, Xing Lu, Rui Sun, Lin Wang, Lisheng Zheng, Yanfang Ye, Yingna Bao, Yanqun Xiang, Xiang Guo
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0057830
Abstract: Background Aberrant expression of C-X-C motif chemokine 5 (CXCL5) contributes to the progression of various cancers. This study analyzed the clinical significance of serum CXCL5 (sCXCL5) levels of nasopharyngeal carcinoma (NPC) patients, with the goal of building a novel prognostic score model. Experimental Design Serum samples were collected prior to treatment from 290 NPC patients for the detection of sCXCL5 with ELISA. Half of the patients (n = 145) were randomly assigned to the training set to generate the sCXCL5 cutoff point using receiver operator characteristic (ROC) analysis, while the other half (n = 145) were assigned to the testing set for validation. Associations between sCXCL5 levels and clinical characteristics were analyzed. A prognostic score model was built using independent predictors derived from multivariate analysis. A concordance index (C-Index) was used to evaluate prognostic ability. Results The sCXCL5 cutoff point was 0.805 ng/ml. Sex, age, histology, T classification, clinical classification and local recurrence were not associated with sCXCL5 levels. However, sCXCL5 levels were positively associated with N classification, distant metastasis and disease progression (P<0.05). A high sCXCL5 level predicted poor 6-year overall survival (OS), poor 6-year distant metastasis-free survival (DMFS), and poor 6-year progression-free survival (PFS). A prognostic score model was subsequently constructed based on sCXCL5 levels and clinical classification (C-C model), which are independent predictors of OS, DMFS, and PFS, as confirmed by the multivariate analysis. Furthermore, this novel model successfully divided the patients into four risk subgroups in the training set, the testing set and the entire set of patients. The C-Indices were 0.751 and 0.762 for the training set and the testing set, respectively. Conclusions sCXCL5 level was determined to be an independent prognostic factor for NPC patients. The novel statistical C-C model, which includes sCXCL5 levels and clinical classification, could be helpful in predicting the prognosis of NPC patients.
Cause Analysis to Farmers’ No Removal from Immigrant of Voluntary Poverty Alleviation of in Shanxi Province and Policy Recommendations  [PDF]
Yanfang Xu, Longyi Xue, Yaolin Wang
Open Journal of Social Sciences (JSS) , 2016, DOI: 10.4236/jss.2016.44021
Abstract: In the implementation of the voluntary poverty alleviation migration policy, some rich villagers have moved but some still live in the original place. This phenomenon is a universal social problem, and those farmers still maintain the original living standards and even lower than those be-fore the implementation of voluntary poverty alleviation immigration policy. The article takes a poverty-stricken country in Shanxi Province as a case to find out the reasons for the left-behind farmers, to explore the accurate poverty alleviation in the voluntary poverty alleviation in Shanxi Province, and to put forward the corresponding suggestions.
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