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Search Results: 1 - 10 of 41109 matches for " Yan Guan "
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A Numerical Method for Shape Optimal Design in the Oseen Flow with Heat Transfer  [PDF]
Wenjing Yan, Axia Wang, Guoxing Guan
Journal of Applied Mathematics and Physics (JAMP) , 2015, DOI: 10.4236/jamp.2015.310158
Abstract: This paper is concerned with the optimal design of an obstacle located in the viscous and incompressible fluid which is driven by the steady-state Oseen equations with thermal effects. The structure of shape gradient of the cost functional is derived by applying the differentiability of a minimax formulation involving a Lagrange functional with a space parametrization technique. A gradient type algorithm is employed to the shape optimization problem. Numerical examples indicate that our theory is useful for practical purpose and the proposed algorithm is feasible.
Water Quality Evaluation Using Back Propagation Artificial Neural Network Based on Self-Adaptive Particle Swarm Optimization Algorithm and Chaos Theory  [PDF]
Mengshan Li, Wei Wu, Bingsheng Chen, Lixin Guan, Yan Wu
Computational Water, Energy, and Environmental Engineering (CWEEE) , 2017, DOI: 10.4236/cweee.2017.63016
Abstract: To overcome the shortcomings of the traditional methods of water quality evaluation, in this paper, a novel model combines particle swarm optimization (PSO), chaos theory, self-adaptive strategy and back propagation artificial neural network (BP ANN) that was proposed to evaluate the water quality of Weihe River in China. An improved PSO algorithm with a self-adaptive inertia weight and a chaotic learning factor tuned by logistic function was developed and used to optimize the network parameters of BP ANN. The values of average absolute deviation (AAD), root mean square error of prediction (RMSEP) and squared correlation coefficient are 0.0061, 0.0163 and 0.9903, respectively. Compared with other methods, such as BP ANN, and PSO BP ANN, the proposed model displays optimal prediction performance with high precision and good correlation. The results show that the proposed method has the good prediction ability for evaluating water quality. It is convenient, reliable and high precision, which provides good analysis and evaluation method for water quality.
Drought-Resistance Index in Rice Backcross Lines after Anthesis
Wu Na,Guan Yongsheng,Shi Yan
Pakistan Journal of Biological Sciences , 2007,
Abstract: In this study, many indexes correlated with drought resistance including yield components, chlorophyll content, the content of proline, the content of malondiadehyde (MDA), the activity of superoxide dismatase (SOD), the content of peroxides (POD) and catalase (CAT) activity soluble protein content and leaf area in flag leaves were measured under water stress after flowering in five rice backcross combinations. The indexes for drought resistance were screened by the correlation and the gray relationship analysis, under water stress after flowering. The results indicated that after flowering, rate of seeds fertilization was significantly correlated with yield remarkably. And proline content, MDA content in flag leaf and leaf areas were significantly influenced with drought resistance in rice, which indicated that it is feasible to predict the drought resistance in rice after flowering. According to the gray relationship analysis, ability of drought resistance in five rice backcross combinations is the following, the combination 5> combination 1>combination 4>combination 3>combination 2. Results were generally consistent with the performance in field, which indicated that it is reasonable to predict the drought resistance in rice after flowering with the four indexes screened out in this study.
Analysis of differential gene expression profile in peripheral blood of patients with chronic hepatitis B and syndromes of dual deficiency of liver and kidney yin and accumulation of dampness heat
Yan Guan,Shi-bing Su
Zhong Xi Yi Jie He Xue Bao , 2012,
Abstract: OBJECTIVE: To investigate the differential gene expression profile in two typical traditional Chinese medicine (TCM) syndromes of patients with chronic hepatitis B (CHB), and to find the relationship between TCM syndromes and gene expressions.METHODS: Patients with CHB were collected from Department of Liver Diseases of Longhua Hospital in Shanghai and diagnosed as dual deficiency of liver and kidney yin syndrome (n=3) or accumulation of dampness heat syndrome (n=3). Three healthy volunteers were used as a control. Blood samples were collected before treatment. After total RNA was isolated from leukocytes, the gene expression profiles were detected by microarray. For confirming the gene expressions, a further 10 patients with dual deficiency of liver and kidney yin syndrome or accumulation of dampness heat syndrome and 10 healthy volunteers were enrolled. Their peripheral blood was used to test the gene expression by real-time reverse transcription-polymerase chain reaction (RT-PCR) which was differently expressed by microarray.RESULTS: Microarray analysis identified that there were significant differences in gene expression between patients with dual deficiency of liver and kidney yin syndrome and patients with accumulation of dampness heat syndrome, as well as between CHB patients and healthy volunteers. Patients with dual deficiency of liver and kidney yin syndrome and accumulation of dampness heat syndrome were fully distinguished by clustering of 403 differentially expressed genes (P<0.05). A total of 239 genes were significantly differentially expressed (absolute value of foldchange≥2, P<0.05), among which 142 were up-regulated and 97 were down-regulated. Genes specially regulated by the dual deficiency of liver and kidney yin syndrome were mainly related to peroxide activity and stem cell maintenance; genes specially regulated by the accumulation of dampness heat syndrome were mainly related to cytokines, immune and inflammatory responses. ATP-binding cassette, sub-family C (CFTR/MRP), member 3, peroxisome proliferator-activated receptor α and phosphatidic acid phosphatase type 2A mRNA expressions detected by RT-PCR were similar to the results of microarray.CONCLUSION: Differential gene expressions are observed in CHB patients with dual deficiency of liver and kidney yin syndrome and accumulation of dampness heat syndrome, indicating that there is molecular foundation in the classification of TCM syndrome. The preliminary findings of this study suggest that TCM syndrome types are related to gene expression.
Research on bulk-cargo-port berth assignment based on priority of resource allocation
Chunfang Guo,Zhongliang Guan,Yan Song
Journal of Industrial Engineering and Management , 2013, DOI: 10.3926/jiem.673
Abstract: Purpose: The purpose of this paper is to propose a Priority of Resource Allocation model about how to utilize the resources of the port efficiently, through the improvement of traditional ant colony algorithm, the ship-berth matching relation constraint matrix formed by ontology reasoning. Design/methodology/approach: Through questionnaires?Explore factor analysis (EFA) and principal component analysis, the authors extract the importance of the goods, the importance of customers, and type of trade as the main factors of the ship operating priority. Then the authors combine berth assignment problem with the improved ant colony algorithm, and use the model to improve ship scheduling quality. Finally, the authors verify the model with physical data in a bulk-cargo-port in China. Findings: Test by the real data of bulk cargo port, it show that ships’ resource using priority and the length of waiting time are consistent; it indicates that the priority of resource allocation play a prominent role in improving ship scheduling quality. Research limitations: The questionnaires is limited in only one port group, more related Influence factors should be considered to extend the conclusion. Practical implications: The Priority of Resource Allocation model in this paper can be used to improve the efficiency of the dynamic berth assignment. Originality: This paper makes the time of ship in port minimized as the optimization of key indicators and establishes a dynamic berth assignment model based on improved ant colony algorithm and the ontology reasoning model.
Expressions and Their Significances of Vascular Endothelial Growth Factor-C mRNA and Epidermal Growth Factor Receptor mRNA in Non-small Cell Lung Cancer Tissues and Lymph Node Tissues
Yan GUAN,Qisen GUO,Hongsheng ZENG
Chinese Journal of Lung Cancer , 2010,
Abstract: Background and objective It has been proven that some molecular markers play important roles in diagnosis, clinical prediction and prognosis monitoring for lung cancer. The aim of this study is to investigate the expressions and their significances of vascular endothelial growth factor-C (VEGF-C) mRNA and epidermal growth factor receptor (EGFR) mRNA in non-small cell lung cancer (NSCLC) tissues and lymph node tissues. Methods The expressions of VEGF-C mRNA and EGFR mRNA were detected in tumor tissues and lymph node tissues by reverse transcription polymerase chain reaction (RT-PCR) and real-time fluorescence quantitative PCR. The relationship and correlation between the expressions of VEGF-C mRNA, EGFR mRNA and clinicopathologic characteristics were analyzed. Results The expressions of VEGF-C mRNA and EGFR mRNA in tumor tissues and lymph node tissues were significantly higher than those in control group (P < 0.05). The expressions of VEGF-C mRNA and EGFR mRNA were much higher in patients with lymph node metastasis than those without lymph node metastasis (P < 0.05). The expressions of VEGF-C mRNA and EGFR mRNA in tumor tissues and lymph node tissues were significantly correlated (r=0.834, P < 0.001; r=0.817, P < 0.001). Conclusion The overexpressions of VEGF-C and EGFR genes are closely related to lymph node metastasis. VEGF-C mRNA and EGFR mRNA are valuable biomarkers for early diagnosis, clinical prediction and prognosis for lung cancer.
Tour Route Multiobjective Optimization Design Based on the Tourist Satisfaction
Yan Han,Hongzhi Guan,Jiaying Duan
Discrete Dynamics in Nature and Society , 2014, DOI: 10.1155/2014/603494
Abstract: The question prompted is how to design the tour route to make the tourists get the maximum satisfactions considering the tourists’ demand. The influence factors of the tour route choices of tourists were analyzed and tourists’ behavior characteristics and psychological preferences were regarded as the important influence factors based on the tourist behavioral theories. A questionnaire of tourists’ tour route information and satisfaction degree was carried out. Some information about the scene spot and tourists demand and tour behaviors characteristic such as visit frequency, number of attractions visited was obtained and analyzed. Based on the convey datum, tour routes multiobjective optimization functions were prompted for the tour route design regarding the maximum satisfaction and the minimum tour distance as the optimal objective. The available routes are listed and categorized. Based on the particle swarm optimization model, the priorities of the tour route are calculated and finally the suggestion depth tour route and quick route tour routes are given considering the different tour demands of tourists. The results can offer constructive suggestions on how to design tour routes on the part of tourism enterprises and how to choose a proper tour route on the part of tourists. 1. Introduction With the development of economics, more and more people have leisure time to travel. During the travel, it is necessary for the tourist to determine the travel destination and traffic mode and visit more scenic spots and historical sites in the limited time budget and get the maximum satisfactions. For some tourists, it will take them some time to determine the tour route before or during the travel [1], especially for those tourists who visit the scenic spot for the first time. So for tourism enterprises the most important thing is to provide reasonable tour route and different scenic spots to attract more tourists and enhance the attractions charm and popularity. More and more tour route products are analyzed and provided so as to meet the different demands of tourists. And the problem prompted for the tourism enterprises is how to design and provide the tour route system to make the tourists get the maximum satisfactions according to the tourists’ demand, what the tourists’ demand is, and how to obtain the tourists’ demand. The tour route system refers to the continuous space chain connected with each landscape feature point of a tourist area with the concepts of time and space. It has three different levels: one is accessibility tourism routes connected by
Lipschitz metric for the modified two-component Camassa-Holm system
Chunxia Guan,Kai Yan,Xuemei Wei
Mathematics , 2015,
Abstract: This paper is devoted to the existence and Lipschitz continuity of global conservative weak solutions in time for the modified two-component Camassa-Holm system on the real line. We obtain the global weak solutions via a coordinate transformation into the Lagrangian coordinates. The key ingredients in our analysis are the energy density given by the positive Radon measure and the proposed new distance functions as well.
Measuring Two-Event Structural Correlations on Graphs
Ziyu Guan,Xifeng Yan,Lance M. Kaplan
Computer Science , 2012,
Abstract: Real-life graphs usually have various kinds of events happening on them, e.g., product purchases in online social networks and intrusion alerts in computer networks. The occurrences of events on the same graph could be correlated, exhibiting either attraction or repulsion. Such structural correlations can reveal important relationships between different events. Unfortunately, correlation relationships on graph structures are not well studied and cannot be captured by traditional measures. In this work, we design a novel measure for assessing two-event structural correlations on graphs. Given the occurrences of two events, we choose uniformly a sample of "reference nodes" from the vicinity of all event nodes and employ the Kendall's tau rank correlation measure to compute the average concordance of event density changes. Significance can be efficiently assessed by tau's nice property of being asymptotically normal under the null hypothesis. In order to compute the measure in large scale networks, we develop a scalable framework using different sampling strategies. The complexity of these strategies is analyzed. Experiments on real graph datasets with both synthetic and real events demonstrate that the proposed framework is not only efficacious, but also efficient and scalable.
Preparation, properties, and cell attachment/growth behavior of chitosan/acellular derm matrix composite materials  [PDF]
Tao Lu, Rui xin Li, Yan Zhang, Yu xian Yan, Yong Guo, Jing Guan, Ji min Wu, Zhi hong LI, Bo Ning, Shu jie Huang, Xi zheng Zhang
Journal of Biomaterials and Nanobiotechnology (JBNB) , 2011, DOI: 10.4236/jbnb.2011.22016
Abstract: Composite membranes and sponge scaffolds consisting chitosan (CS) and acellular derm matrix (ADM) in six ratios were prepared by solvent evaporation technique and freeze-drying method, respectively. The composite materials were characterized by water contact angle measurement, scanning electron microscopy (SEM), water absorption and HaCat cells compatibility. The SEM result showed that CS/ADM three-dimensional (3D) micro-porous structures were successfully produced. The water absorption value of all scaffolds was over 18 times of its initial weight, which is high enough for skin regeneration scaffold, but there were no significant differences of water absorption ratio between deionized water and PBS solution for same scaffold (P > 0.05). HaCat cells were distributed uniformly on the surfaces of membrane 4-6, and an almost confluent monolayer was formed on membrane 6 on the fifth day, whereas cells maintained round and spherical in shape on the surface of membrane 1. The results showed that the cell compatibility of pure CS membrane needed to be improved, and addition of ADM realized this purpose. The results of compatibility of HaCat cells on scaffolds showed that the cell proliferated well on the scaffolds 3 and 4. In our study, the cell’s attachment and growth on the composite membranes was mainly determined by the content of the membrane, whereas the cell’s attachment and growth in the scaffolds was determined by both the content and structure of the scaffolds.
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