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Search Results: 1 - 10 of 120126 matches for " Xueqin Wang "
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The Redistribution Effect of Social Security System under Birth Control  [PDF]
Xueqin Duan
Open Journal of Social Sciences (JSS) , 2018, DOI: 10.4236/jss.2018.63014
This paper establishes an OLG model to analyze the long-term effect of social security on inequality under birth control. We study the effect of population policy and social security on fertility and education of families with different income. Then this effect determines the evolution of inequality. The analyses suggest that the effect of social security on inequality in the next generation is depended on population policy and the differentiation of family care.
Identification and function analysis of spectrin-like protein in pollen tubes of lily (Lilium davidii Duch)
Xueqin Zhang,Ming Yuan,Xuechen Wang
Chinese Science Bulletin , 2004, DOI: 10.1007/BF03184130
Abstract: The elongation of pollen tube is an important process of sexual reproduction in higher plant. Cytoskeleton plays a major regulatory role in the elongation of pollen tubes. But whether membrane skeleton is involved in the pollen tube elongation is not clear. In this study, immunochemical detection of spectrin-like protein has been carried out in pollen tubes. By use of 2-dimensional electrophoresis(2DE) and western blotting, two spectrin-like proteins are found, one is 150 kD, and the other is 105 kD, with pI being 4.54 and 4.39, respectively. 150 kD spectrin-like protein is located in plasma membrane of pollen tube and 105 kD spectrin-like protein is located in cytoplasm, probably functioning as a subunit to form a dimmer (210 kD)in vivo. The elongation of pollen tubes is inhibited after spectrin antibody was injected into a growing pollen tube. These results suggest that spectrin-like proteins exist in pollen tube and play an important regulating role in the elongation process of pollen tubes from lily.
A unifying generalization of Sperner's theorem
Matthias Beck,Xueqin Wang,Thomas Zaslavsky
Mathematics , 2001,
Abstract: Sperner's bound on the size of an antichain in the lattice P(S) of subsets of a finite set S has been generalized in three different directions: by Erdos to subsets of P(S) in which chains contain at most r elements; by Meshalkin to certain classes of compositions of S; by Griggs, Stahl, and Trotter through replacing the antichains by certain sets of pairs of disjoint elements of P(S). We unify Erdos's, Meshalkin's, and Griggs-Stahl-Trotter's inequalities with a common generalization. We similarly unify their accompanying LYM inequalities. Our bounds do not in general appear to be the best possible.
Plasmid-encoded NP73-102 modulates atrial natriuretic peptide receptor signaling and plays a critical role in inducing tolerogenic dendritic cells
Zhang Weidong,Cao Xueqin,Chen Dongqing,Wang Jia-wang
Genetic Vaccines and Therapy , 2011, DOI: 10.1186/1479-0556-9-3
Abstract: Background Atrial natriuretic peptide (ANP) is an important endogenous hormone that controls inflammation and immunity by acting on dendritic cells (DCs); however, the mechanism remains unclear. Objective We analyzed the downstream signaling events resulting from the binding of ANP to its receptor, NPRA, and sought to determine what aspects of this signaling modulate DC function. Methods We utilized the inhibitory peptide, NP73-102, to block NPRA signaling in human monocyte-derived DCs (hmDCs) and examined the effect on DC maturation and induced immune responses. The potential downstream molecules and interactions among these molecules involved in NPRA signaling were identified by immunoprecipitation and immunoblotting. Changes in T cell phenotype and function were determined by flow cytometry and BrdU proliferation ELISA. To determine if adoptively transferred DCs could alter the in vivo immune response, bone marrow-derived DCs from wild-type C57BL/6 mice were incubated with ovalbumin (OVA) and injected i.v. into C57BL/6 NPRA-/- knockout mice sensitized and challenged with OVA. Lung sections were stained and examined for inflammation and cytokines were measured in bronchoalveolar lavage fluid collected from parallel groups of mice. Results Inhibition of NPRA signaling in DCs primes them to induce regulatory T cells. Adoptive transfer of wild type DCs into NPRA-/- mice reverses the attenuation of lung inflammation seen in the NPRA-knockout model. NPRA is associated with TLR-2, SOCS3 and STAT3, and inhibiting NPRA alters expression of IL-6, IL-10 and TGF-β, but not IL-12. Conclusions Modulation of NPRA signaling in DCs leads to immune tolerance and TLR2 and SOCS3 are involved in this induction.
Construction of National High-Quality Courses for LIS in China  [PDF]
Changping Hu, Xueqin Zhao
Journal of Service Science and Management (JSSM) , 2010, DOI: 10.4236/jssm.2010.31022
Abstract: The paper first introduces the background of Martin Trow’s theory of how to develop mass higher education and then brings up the necessity of Chinese course teaching reform. It introduces the current situation of the construction of the National High-quality Courses (NHCs) in China. And taking the practice of Wuhan University’s library and information science (LIS) course teaching as an example, the paper also discusses the implementation of this project, focusing on two aspects: a new system of LIS course teaching and network platform construction. The paper concludes by recommending that, for successful LIS NHCs, it is necessary to transform our educational ideology, strengthen our innovation, and set up a more beneficial teaching environment for innovation cultivation.
Involvement of TIP60 acetyltransferase in intracellular Salmonella replication
Xueqin Wang, Dongju Li, Di Qu, Daoguo Zhou
BMC Microbiology , 2010, DOI: 10.1186/1471-2180-10-228
Abstract: In an attempt to identify host proteins that interact with SseF, we conduct a yeast two-hybrid screening of human cell cDNA library using SseF as the bait. We identified that TIP60, an acetyltransferase, interacts with SseF. We showed that the TIP60 acetylation activity was increased in the presence of SseF, and TIP60 was upregulated upon Salmonella infection. In addition, TIP60 is required for efficient intracellular Salmonella replication in macrophages.Taken together, our data suggest that Salmonella may use SseF to exploit the host TIP60 acetyltransferase activity to promote efficient Salmonella replication inside host cells.Protein acetylation adds the acetyl group on either the amino-terminal residues or on the epsilon-amino group of lysine residues. Lysine acetylation affects many protein functions, including DNA binding, protein-protein interactions, and protein stability. TIP60 catalyzes histone acetylation [1,2]. It was originally identified as a cellular acetyltransferase protein that interacts with HIV-1 Tat [3]. Over-expression of TIP60 increased Tat transactivation of the HIV-1 promoter [3]. Recent studies found that TIP60 has diverse functions involved in transcription, cellular signaling, DNA damage repair, cell cycle checkpoint control and apoptosis [2,4,5].Salmonella enterica serovar Typhimurium (S. typhimurium) causes gastrointestinal diseases in humans and typhoid-like fever in the mouse. S. typhimurium encodes two Type III secretion systems within the Salmonella pathogenicity islands 1 and 2 (SPI-1 and SPI-2) that are required for Salmonella entry and subsequent survival inside the host cells, respectively [6-10]. Following entry into the host cells, S. typhimurium replicates within a membrane-bound compartment termed Salmonella-containing vacuole (SCV). Previous studies have shown that SifA, SseF and SseG are involved in the formation of Salmonella induced filaments (Sifs) that are required for maintaining the SCV [11-13].SseF, working together

Xu Xianggui Zhu Jianqin Wang Xueqin,

动物学研究 , 1992,
Abstract: Intraeerebroventricularly (i. c. v.) administered GARA (2. 4. 6 umol) significantly accelerated the development of gastric ulcer induced by ethanol (o. p.) in mice in a dose dependent manner, whereas GABA (i. p. 100 umol) could not modify the ethanol-induced ulcer in mice. Atropine (s. c. 0.2mg/kg) exacerbated the ethanol-induced ulcer significantly, while blocking tht: exacerbation of ulcer induced by GABA partly. Regetine (i. m. 2.5 mg/kg) potentiated the ethanol-induced ulcer weakly, and had no effect on the exacerbation of ulcer induced by GABA. These results suggested that exsragenetic GABA exacerbates the ethanol-induced gastric ulcer through central GABA-crgic mechanisms, but not peripherally. Vagus may contribute to gastric protective effect against ulceration. It may be one of main pathway in GABA's action. Sympathetic nerve maybe have relationship with the GABA-ergic mechanisms.
Experimental Study on Anti-inflammation and Decreasing Pain Effects of Extracts of Periplaneta Americana
Xiaoqin Xiao,Shiping Wang,Chen Luo,Xueqin Liu
Modern Applied Science , 2009, DOI: 10.5539/mas.v2n4p12
Abstract: To investigate the effects of extracts of Periplaneta Americana on anti-inflammation and decreasing pain, inhibitive effects of the extracts were investigated in different inflammatory models, for instance, cotton induced-granuloma tissue proliferous inflammation of mice, egg white induced rat paw edema, stress gastric ulcer of rats, acetic acid induced writhing response of mice, and hot metal board induced-pain of mice. Results showed that extracts of Periplaneta Americana played important roles in anti-inflammation induced by tumefaction, effusion and hyperplasia, and in decreasing pain. There was obviously statistical difference as compared with control group. It can be concluded that extracts of Periplaneta Americana are indeed worthy of further development for potential medicinal value.
Forecasting Cohesionless Soil Highway Slope Displacement Using Modular Neural Network
Yanyan Chen,Shuwei Wang,Ning Chen,Xueqin Long
Discrete Dynamics in Nature and Society , 2012, DOI: 10.1155/2012/504574
meta-analysis of Serum Tumor Markers in Lung Cancer
Xianfeng LU,Xueqin YANG,Zhimin ZHANG,Dong WANG
Chinese Journal of Lung Cancer , 2010,
Abstract: Background and objective The detection of serum tumor markers is of great value for early diagnosis of lung cancer. The aim of this study is to summarize the clinic significance characteristics of serum markers contributing to the detection of lung cancer. Methods References about serum markers of lung cancer were estimated using meta-analysis method. 712 references which included more than 20 cases, 20 controls, the serum markers of 52 832 patients with malignancies and 32 037 patients as controls were evaluated. Results Overall the detection of 13 markers play a significant part in lung cancer diagnosis. The sensitivity of CEA, CA125, CYFRA21-1, TPA, SCCAg, DKK1, NSE, ProGRP in the patients’ serum with lung cancer were 47.50%, 50.11%, 57.00%, 50.93%, 49.00%, 69.50%, 39.73%, 51.48% and the specificity were 92.34%, 80.19%, 90.16%, 88.41%, 91.07%, 92.20%, 89.11%, 94.89%. In the combined analysis of tumor markers: the sensitivity, specificity of NSE+ProGRP were 88.90% and 72.82% in diagnosis of small cell lung cancer, respectively. In diagnosis of squamous corcinoma, the sensitivity and specificity of TSGF+SCCAg+CYFRA21-1 were 95.30% and 74.20%. The the sensitivity and specificity of CA153+Ferrtin+CEA were 91.90% and 44.00% in diagnosis of lung cancer. Conclusion Although the assay of tumor markers in serum is useful for diagnosis of early lung cancer, the sensitivity and specificity are low. Combined detection of these tumor markers could increase sensitivity and specificity.
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