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Search Results: 1 - 10 of 28447 matches for " Xuegang Sun "
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Translational Chinese Medicine: A Way for Development of Traditional Chinese Medicine  [PDF]
Xuegang Sun, Donglan Lin, Weikang Wu, Zhiping Lv
Chinese Medicine (CM) , 2011, DOI: 10.4236/cm.2011.24029
Abstract: Translational Chinese medicine is one of the latest developing fields in traditional Chinese medicine. In this paper, we discuss the “3 w” namely, “what is”, “why to advance”, “how to carry out” and the significance of translational Chinese medicine. To overcome the innate drawbacks of traditional Chinese medicine (TCM), the basic theory of TCM had better be refreshed. The safety and efficacy of classic formulae and therapy experience of TCM should be evaluated based on strict quality control and reaffirmed with evidence based medicine. The significance of translational Chinese medicine is to transform Chinese medicine into a balanced, personalized medicine with sound safety, good efficacy and strict quality control.
Analysis of EET on Ca increasing the melting point of Mg17Al12 phase
Xuegang Min,Wenwen Du,Feng Xue,Yangshan Sun
Chinese Science Bulletin , 2002, DOI: 10.1360/02tb9243
Abstract: The present investigation showed that the additions of Ca to the alloy AZ91 were mainly dissolved into the Mg17Al12 phase and increased its melting point and thermal stability, which would have great effects on the high-temperature properties of AZ91 alloy. The empirical electron theory (EET) of solid and molecules was used to calculate the valence electron structures (VES) of Mg17Al12 intermetallic compound with and without Ca addition. The results showed that Ca dissolving in Mg17Al12 phase increased the strength of bonds that control the thermal stability of Mg17Al12 phase. Additions of Ca also made the distribution of the valence electrons on the dominant bond network more uniform in the whole unit cell of Mg17Al12. The theoretical conclusions well account for the experimental results.
The Stability and Numerical Dispersion Study of the ADI-SFDTD Algorithm
Zongxin Liu,Yiwang Chen,Xin Xu,Xuegang Sun
Modern Applied Science , 2011, DOI: 10.5539/mas.v5n6p157
Abstract: In this letter, the alternating-direction-implicit (ADI) technique is applied to Symplectic finite-difference time-domain (SFDTD) method, the curl operator is endued with two different styles when doing computation from the th progression to th progression. It holds the advantages of both ADI-FDTD and SFDTD, not only eliminating the restriction of the Courant-Friedrich-Levy (CFL), but also holding the inner characteristics of Maxwell’s equations. The analytical accuracy and efficiency of the proposed method is verified good.
A Variational Model for Removing Multiple Multiplicative Noises  [PDF]
Xuegang Hu, Yan Hu
Open Journal of Applied Sciences (OJAppS) , 2015, DOI: 10.4236/ojapps.2015.512075
Abstract: The problem of multiplicative noise removal has been widely studied in recent years. Many methods have been used to remove it, but the final results are not very excellent. The total variation regularization method to solve the problem of the noise removal can preserve edge well, but sometimes produces undesirable staircasing effect. In this paper, we propose a variational model to remove multiplicative noise. An alternative algorithm is employed to solve variational model minimization problem. Experimental results show that the proposed model can not only effectively remove Gamma noise, but also Rayleigh noise, as well as the staircasing effect is significantly reduced.
An Improved Moving Object Detection Algorithm Based on Gaussian Mixture Models  [PDF]
Xuegang Hu, Jiamin Zheng
Open Journal of Applied Sciences (OJAppS) , 2016, DOI: 10.4236/ojapps.2016.67045
Abstract: Aiming at the problems that the classical Gaussian mixture model is unable to detect the complete moving object, and is sensitive to the light mutation scenes and so on, an improved algorithm is proposed for moving object detection based on Gaussian mixture model and three-frame difference method. In the process of extracting the moving region, the improved three-frame difference method uses the dynamic segmentation threshold and edge detection technology, and it is first used to solve the problems such as the illumination mutation and the discontinuity of the target edge. Then, a new adaptive selection strategy of the number of Gaussian distributions is introduced to reduce the processing time and improve accuracy of detection. Finally, HSV color space is used to remove shadow regions, and the whole moving object is detected. Experimental results show that the proposed algorithm can detect moving objects in various situations effectively.
Geometric Correlation between Dirac Equation and Yang-mills Equation/ Maxwell Equation
Xuegang Yu
Physics , 2011,
Abstract: The problem about geometric correspondence of Dirac particle and contain quality item of Yang-Mills equation has always not been solved.This paper introduced the hyperbolic imaginary unit in Minkowski space, established a classes of Dirac wave equations with t'Hooft matrices.In lightlike region of Minkowski space,we can discuss the hermitian conjugate transformation of Dirac positive particle and antiparticle, find the space-time corresponding points of Dirac particle,and draw Feynman clip-art though the geometrical relation between timelike region and lightlike region.The coupling of motion equation of Dirac positive particle and antiparticle can get Klein-Gordon equation, when it reach classical approximate we can get Schrodinger equation,and this illustrated that p meson or m meson may be composite particle. Using the relation of timelike region and lightlike region in Minkowski momentum space to renormalize the rest mass of particles,we can describe the geometric relation between rest mass and electromagnetic mass of particles. Then, we can elicit the Yang-Mills equation with electromagnetic mass through four Dirac wave equations with the hermitian conjugate transformation relation, and further launch the common forms of Maxwell equations.
Paired-domination Number in Cubic Graphs

Chen Xuegang,Sun Liang,Xing Huaming,

数学物理学报(A辑) , 2007,
Abstract: 设G=(V,E)是一个简单图,对任意的顶点子集合S■V,GS]表示图G中由S所导出的子图.如果S是G的一个控制集并且GS]包含至少一个完备匹配,则称S是G的一个对控制集.G中对控制集的最少的顶点数称为G的对控制数,记为γp(G).该文证明了对任意有n点的连通立方图G,γp(G)≤(3n)/5.
Alocasia cucullata Exhibits Strong Antitumor Effect In Vivo by Activating Antitumor Immunity
Qiuxian Peng, Hongbing Cai, Xuegang Sun, Xin Li, Zhixian Mo, Jue Shi
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0075328
Abstract: Chinese herbal medicines have long been used to treat various illnesses by modulating the human immune response. In this study, we investigate the immuno-modulating effect and antitumor activity of Alocasia Cucullata (AC), a Chinese herb traditionally used to treat infection and cancer. We found that the whole water extract of AC roots could significantly attenuate tumor growth in mouse tumor models. The median survival time of the AC-treated mice was 43 days, 16 days longer than that of the control group. Moreover, the AC-treated mice showed substantially higher induction of key antitumor cytokines, such as IL-2, IFN-γ, and TNF-α, indicating that AC may exert antitumor effect by activating antitumor immunity. To further pinpoint the cellular and molecular mechanism of AC, we studied the dose response of a human monocytic cell line, THP-1, to the whole water extract of AC. Treatment of the AC extract significantly induced THP-1 differentiation into macrophage-like cells and the differentiated THP-1 showed expression of specific macrophage surface markers, such as CD11b and CD14, as well as productions of antitumor cytokines, e.g. IFN-γ and TNF-α. Our data thus point to AC as potentially a new, alternative immuno-modulating herbal remedy for anticancer treatment.
Tanshinol Attenuates the Deleterious Effects of Oxidative Stress on Osteoblastic Differentiation via Wnt/FoxO3a Signaling
Yajun Yang,Yanjie Su,Dongtao Wang,Yahui Chen,Tie Wu,Gang Li,Xuegang Sun,Liao Cui
Oxidative Medicine and Cellular Longevity , 2013, DOI: 10.1155/2013/351895
Abstract: There is now increasing evidence which suggests a pivotal role for oxidative stress in the development and progression of osteoporosis. We confirm herein the protective effects of natural antioxidant Tanshinol against oxidative stress in osteoblastic differentiation and the underlying mechanism. Our results show that hydrogen peroxide (H2O2) leads to accumulation of reactive oxygen species (ROS), decrease in cell viability, cell cycle arrest and apoptosis in a caspase-3-dependent manner, and inhibition of osteoblastic differentiation. Tanshinol reverses these deleterious consequence triggered by oxidative stress. Moreover, under the condition of oxidative stress, Tanshinol suppresses the activation of FoxO3a transcription factor and expressions of its target genes Gadd45a and catalase (CAT) and simultaneously counteracts the inhibition of Wnt signalling and expressions of target genes Axin2, alkaline phosphatase (ALP), and Osteoprotegerin (OPG). The findings are further consolidated using FoxO3a siRNA interference and overexpression of Tcf4. The results illustrate that Tanshinol attenuates oxidative stress via down-regulation of FoxO3a signaling, and rescues the decrease of osteoblastic differentiation through upregulation of Wnt signal under oxidative stress. The present findings suggest that the beneficial effects of Tanshinol may be adopted as a novel therapeutic approach in recently recognized conditions of niche targeting osteoporosis. 1. Introduction Extensive evidence indicates that “oxidative stress” theory has currently been proposed as a new intensive mechanism that the development and progression of osteoporosis are in connection with an increase of oxidative stress, which leads to degenerative disease of bone tissue [1, 2]. Understanding of oxidative stress is currently a substantial topic of investigation with the aim of developing new ways to diminish negative effects of oxidative damage on bone metabolism [3]. Starting in their mid-40s, both genders experience a progressive decrease in bone mass and bone quality [2], associated with aging [4], some illnesses, or use of medications, such as diabetes or excessive exposure to glucocorticoids [5–7]. Notwithstanding, as for the evidence for physiological levels of reactive oxygen species (ROS) helpful in sustaining cellular function [8], it is generally believed that excessive accumulation of ROS causes oxidative stress and destroys proteins, lipids, and DNA, consequentially leading to cell death [9]. Based on current understanding of the cellular events of bone formation phase in the process
A Peroxisomal Long-Chain Acyl-CoA Synthetase from Glycine max Involved in Lipid Degradation
Lili Yu, Xiaoli Tan, Bingjun Jiang, Xuegang Sun, Shoulai Gu, Tianfu Han, Wensheng Hou
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0100144
Abstract: Seed storage oil, in the form of triacylglycerol (TAG), is degraded to provide carbon and energy during germination and early seedling growth by the fatty acid β-oxidation in the peroxisome. Although the pathways for lipid degradation have been uncovered, understanding of the exact involved enzymes in soybean is still limited. Long-chain acyl-CoA synthetase (ACSL) is a critical enzyme that activates free fatty acid released from TAG to form the fatty acyl-CoA. Recent studies have shown the importance of ACSL in lipid degradation and synthesis, but few studies were focused on soybean. In this work, we cloned a ACSL gene from soybean and designated it as GmACSL2. Sequence analysis revealed that GmACSL2 encodes a protein of 733 amino acid residues, which is highly homologous to the ones in other higher plants. Complementation test showed that GmACSL2 could restore the growth of an ACS-deficient yeast strain (YB525). Co-expression assay in Nicotiana benthamiana indicated that GmACSL2 is located at peroxisome. Expression pattern analysis showed that GmACSL2 is highly expressed in germinating seedling and strongly induced 1 day after imbibition, which indicate that GmACSL2 may take part in the seed germination. GmACSL2 overexpression in yeast and soybean hairy root severely reduces the contents of the lipids and fatty acids, compared with controls in both cells, and enhances the β-oxidation efficiency in yeast. All these results suggest that GmACSL2 may take part in fatty acid and lipid degradation. In conclusion, peroxisomal GmACSL2 from Glycine max probably be involved in the lipid degradation during seed germination.
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