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Search Results: 1 - 10 of 39064 matches for " Xue-Mei Tang "
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DNA immunoadsorption for childhood-onset systemic lupus erythematosus  [PDF]
Xue-Mei Tang, Zong-Yi Zou, Xiao-Dong Zhao, Xue-Lan Chen, Yu Zhang, Qiu Li
Advances in Bioscience and Biotechnology (ABB) , 2012, DOI: 10.4236/abb.2012.34055
Abstract: We present a retrospective review of DNA immunoadsorption (DNA-IA) therapy on clinical symptoms as well as indicators in pediatric cases with systemic lupus erythematosus (SLE), and follow up the short-term curative effects. 16 SLE cases were treated by DNA-IA for 3 times every other day. We observed the changes on clinical manifestations and immunological indicators, in order to compare the alteration of these indicators including clinical manifestations, Systemic Lupus Erythematosus Disease Active Index (SLEDAI) scores, 24 hurinary protein excretion, autoantibodies, serum IgG and complement C3. 13 cases were followed up regularly, within 3 months after DNA-IA therapy, 12 cases of clinical manifestations improved (92.3%). SLEDAI scores in 10 cases decreased from (16.20 ± 12.54) to less than 5 (76.9%), 8 cases of ANA, anti-DNA antibodies were negative (61.5%), 13 cases with IgG level in serum recovered to normal (10.39 ± 4.38) g/L, C3 level rose to normal (1.06 ± 0.23) g/L. 3 to 6 months after IA, clinical manifestations and laboratory examinations in all cases got maximum improved. 9 months after IA, SLEDAI score in 2 cases (15.4%) rose to more than 5, anti-DNA antibody in 2 cases (15.4%) became positive, and 1case (7.7%) with serum C3 decreased again. 2 cases died from multiple organs dysfunction within 3 to 6 months after IA. No serious complications were found during DNA-IA. We recommend that DNA immunoadsorption is a safe and effective therapy for active childhood-onset SLE, which could improve clinical symptoms, eliminate ANA and anti-DNA antibodies. Combining with corticosteroids and immunosuppressive drugs, DNA-IA could significantly reduce the activity of disease and protect vital organs function in the short term.
Comparison of Spinal Block Levels between Laboring and Nonlaboring Parturients Using Combined Spinal Epidural Technique with Intrathecal Plain Bupivacaine
Yu-Ying Tang,Jie Zhou,Xiao-Hui Ren,Xue-Mei Lin
Anesthesiology Research and Practice , 2012, DOI: 10.1155/2012/187132
Abstract: Background. It was suggested that labor may influence the spread of intrathecal bupivacaine using combined spinal epidural (CSE) technique. However, no previous studies investigated this proposition. We designed this study to investigate the spinal block characteristics of plain bupivacaine between nonlaboring and laboring parturients using CSE technique. Methods. Twenty-five nonlaboring (Group NL) and twenty-five laboring parturients (Group L) undergoing cesarean delivery were enrolled. Following identification of the epidural space at the L3-4 interspace, plain bupivacaine 10?mg was administered intrathecally using CSE technique. The level of sensory block, degree of motor block, and hemodynamic changes were assessed. Results. The baseline systolic blood pressure (SBP) and the maximal decrease of SBP in Group L were significantly higher than those in Group NL ( and , resp.). The median sensory level tested by cold stimulation was T6 for Group NL and T5 for Group L ( ). The median sensory level tested by pinprick was T7 for both groups ( ). The degree of motor block was comparable between the two groups ( ). Conclusion. We did not detect significant differences in the sensory block levels between laboring and nonlaboring parturients using CSE technique with intrathecal plain bupivacaine. 1. Introduction Combined spinal epidural (CSE) anesthesia is commonly used for cesarean delivery. It has been suggested that nonlaboring parturients have a higher sensory block level than those in labor during CSE anesthesia [1]. This proposition was derived from combining two independent randomized studies on spinal block levels designed separately for laboring and nonlaboring parturients [2, 3]. There was a 5-dermatome level difference between nonlaboring (C6) [2] and laboring (T3) [3] parturients using 10?mg hyperbaric bupivacaine with CSE technique. However, there has been no previous study examining the effect of labor on the level of the subarachnoid block during CSE. The effect of CSE technique on the spinal block level of hyperbaric bupivacaine in nonlaboring parturients was not consistent. Horstman et al. reported that sensory block level was at T3 with CSE in nonlaboring parturients using 20% higher dose of hyperbaric bupivacaine [4]. We speculate that baricity of the hyperbaric bupivacaine used by Ithnin et al. could be a confounding factor, because the block level could be easily manipulated with the positioning of the parturients when hyperbaric local anesthetic was used. The effect of labor on the spread of local anesthetics may be better examined by
Research Advances in Cryopreservation of Plant Germplasm by Encapsulation-vitrification Method
包埋玻璃化法超低温保存植物种质的研究进展

WU Xue-Mei TANG Hao-Ru,
吴雪梅
,汤浩茹

植物学报 , 2005,
Abstract: Encapsulation-vitrification, a new method for cryopreservation of plant germplasm in recent years, was developed on the basis of vitrification and encapsulation-dehydration. It has many advantages over vitrification and encapsulation-dehydration, because more materials can be treated at the same time, growth is recovered more rapidly after treatment, it is less harmful to the material, and allows for a higher shoot regeneration rate. It has been successfully used to preserve more than 20 species, such as pear, horseradish and wasabi, and shows great application potential in the preservation of plant germplasm resources. This paper introduces the development and advantages of encapsulation-vitrification and the main methods and procedures such as preculture, encapsulation, dehydration, thawing and recovery of culture. The effects of freezing protection and the genetic stability of plant materials preserved with encapsulationvitrification are discussed as well. Further research on encapsulation-vitrification of plant tissue is also suggested.
(RS)-1-[5-(2-Chloropropyl)indolin-1-yl]ethanone
Xue-Mei Yang
Acta Crystallographica Section E , 2011, DOI: 10.1107/s1600536810050476
Abstract: In the title compound, C13H16ClNO, the acetylindoline moiety is roughly planar (r.m.s. deviation = 0.0048 ). The chloropropyl group is out of the plane and is statistically disordered over two positions. Indeed, the Cl and CH3 groups located on the stereogenic carbon exchange with each other. The whole crystal is a racemate. Non-classical C—H...O hydrogen bonds between symmetry-related benzene rings stabilize the crystal structure.
4-(1,3-Thiazolidin-2-yl)phenol
Xue-Mei Yang
Acta Crystallographica Section E , 2009, DOI: 10.1107/s1600536809042135
Abstract: In the title compound, C9H11NOS, the thiazolidinyl ring is almost perpendicular to the phenyl ring with N—C—C—C torsion angles of 71.7 (2) and 107.1 (2)°. In the crystal, molecules are connected via N—H...O and O—H...N hydrogen bonds, forming layers.
(RS)-1-(1-Acetylindolin-5-yl)-2-chloropropan-1-one
Xue-Mei Yang
Acta Crystallographica Section E , 2010, DOI: 10.1107/s1600536810020969
Abstract: The molecule of the title compound, C13H14ClNO2, is roughly planar [maximum deviation = 0.060 (2) ] with the disordered Cl/CH3 group asymetrically distributed on both sides of the mean plane. Indeed, the Cl and CH3 located on the stereogenic carbon exchange each other with occupancy factors in the ratio 0.60:0.40. The whole crystal is a racemate. Non-classical C—H...O hydrogen bonds and π–π interactions [centroid–centroid distance = 3.6959 (9) ] between symmetry-related phenyl rings stabilize the crystal structure.
Integrated traditional Chinese and Western medicine versus Western medicine in treatment of arteriosclerosis obliterans: a systematic review of randomized controlled trials
Xue-mei You
Zhong Xi Yi Jie He Xue Bao , 2010,
Abstract: Background: The conventional therapy for arteriosclerosis obliterans (ASO) is Western medicine. However, it has some adverse effects and does not respond to some patients, and it is also very expensive.Objective: To evaluate the efficacy of integrated traditional Chinese (TCM) and Western medicine (WM) in treatment of ASO.Search strategy: Electronic and manual searches were conducted and the searches ended on May 20, 2009.Inclusion criteria: We included randomized controlled trials (RCT) evaluating integrated TCM and WM (as treatment group) versus WM used alone (as control group), and no language limits were set.Data extraction and analysis: Selection of trials for inclusion, assessment for methodological quality, data extraction and data syntheses were conducted according to protocol of a Cochrane systematic review by the authors.Results: Thirteen RCT were included, which encompassed a total of 968 patients. The results showed that all of the 13 included trials did not report mortality rate of ASO. The studies displayed that the amputation rate in the treatment group was lower than that in the control group, but there was no statistical significance. Ten studies adopted inefficiency analysis and 2 of them showed that the ineffective rate in the treatment group was lower than that in the control group, and the relative risk (RR) and 95% CI were 0.36 [0.13, 0.99]. We performed descriptive analysis on other 8 studies; analyses of secondary outcomes such as intermittent claudication, ankle brachial index, high-density lipoprotein (HDL), and low-density lipoprotein (LDL) showed that integrated TCM and WM therapy was more effective than WM treatment alone; one study showed that WM was better than integrated TCM and WM therapy in decreasing the content of fibrinogen. All of the included trials did not report any critical adverse reactions occurred in the treatment group.Conclusion: The current evidence shows that integrated TCM and WM therapy is safe and effective in treating ASO, and tends to reduce amputation rate, improve intermittent claudication, decrease the levels of fibrinogen, HDL and LDL, and increase ankle brachial index, without obvious adverse reactions. Due to the low methodological quality of trials included, more prospective, multicenter, large-scale, high-quality RCTs are needed.
Comparison of animal models of hyperlipidemia
LIU Xue-Mei
Zhong Xi Yi Jie He Xue Bao , 2004,
Abstract: Objective: To select the proper experimental animal model for research on prevention and treatment of hyperlipidemia. Method: Hyperlipidemia models of mouse, rat, golden hamster, guinea pig, rabbit, pigeon and quail often used in the last ten years were compared. Results: Golden hamster and guinea pig models are similar to human beings in lipid metabolism and have unique superiority in experimental study, while the models of rat, mouse, pigeon and quail have significant difference as compared with human beings. Rabbit is one of the best animal models in studying new drugs for regulating lipid and treating arteriosclerosis. Conclusion: Factors such as the required time, indexes, the duration of making models, and the cost and feeding of animals should be considered in selecting animal models according with the experimental requirements.
The study of intoxication and toxicity of Fructus Xanthii
ZHANG Xue-Mei
Zhong Xi Yi Jie He Xue Bao , 2003,
Abstract: ABSTRACT: Fructus Xanthii is commonly used in rhinology, especially used in treatment of chronic rhinitis and sinusitis. But Fructus Xanthii is toxicant, and it maybe result in poisoning when used excessively, without preparation or in inappropriate preparation. This article reviewed all poisoning cases from 1960 to 2000, its toxicology and methods for detoxification.
Constraints on a scalar-tensor theory with an intermediate-range force by binary pulsars
Xue-Mei Deng
Physics , 2011,
Abstract: Searching for an intermediate-range force has been considerable interests in gravity experiments. In this paper, aiming at a scalar-tensor theory with an intermediate-range force, we have derived the metric and equations of motion (EOMs) in the first post-Newtonian (1PN) approximation for general matter without specific equation of state and $N$ point masses firstly. Subsequently, the secular periastron precession $\dot{\omega}$ of binary pulsars in harmonic coordinates is given. After that, $\dot{\omega}$ of four binary pulsars data (PSR B1913+16, PSR B1534+12, PSR J0737-3039 and PSR B2127+11C) have been used to constrain the intermediate-range force, namely, the parameters $\alpha$ and $\lambda$. $\alpha$ and $\lambda$ respectively represent the strength of the intermediate-range force coupling and its length scale. The limits from four binary pulsars data are respectively $\lambda=(4.95\pm0.02)\times10^{8}$m and $\alpha=(2.30\pm0.01)\times10^{-8}$ if $\beta=1$ where $\beta$ is a parameter like standard parametrized post-Newtonian parameter $\beta_{PPN}$. When three degrees of freedom ($\alpha$, $\lambda$ and $\bar{\beta}\equiv\beta-1$) in 1$\sigma$ confidence level are considered, it yields $\alpha=(4.21\pm0.01)\times10^{-4}$, $\lambda=(4.51\pm0.01)\times10^{7}$m and $\bar{\beta}=(-3.30\pm0.01)\times10^{-3}$. Through our research on the scalar-tensor theory with the intermediate-range force, it shows that the parameter $\alpha$ is directly related to the parameter $\gamma$ ($\alpha=(1-\gamma)/(1+\gamma)$). Thus, this presents the constraints on $1-\gamma$ by binary pulsars which is about $10^{-4}$ for three degrees of freedom.
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