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Search Results: 1 - 10 of 67202 matches for " Xu Ning-Ying "
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The Change of ELOD Score and Power under the Real Recombination Rates
真重组率与ELOD值和检验能力的关系 The Change of ELOD Score and Power under the Real Recombination Rates

XU Ning-ying,ZHOU Zhong-er,
徐宁迎
,周仲儿XU Ning-ying,ZHOU Zhong-er

遗传 , 2000,
Abstract: The change of ELOD score and power was studied under the real recombination rates.A total of 50 informative meioses were used in the study as the sample size.The results showed that the linkage analysis was more reliable if the real combination rates between two loci were equal to or smaller than 0 15.
SNPs of Myostatin gene and its genetic effects on carcass traits in chicken
鸡Myostatin基因单核苷酸多态性及其对屠体性状的遗传效应分析

ZHU Zhi,WU Deng-Jun,XU Ning-Ying,
朱智
,吴登俊,徐宁迎

遗传 , 2007,
Abstract: Two polymorphic sites in the first exon 1 of MSTN gene in 180 Wenling grass-chicken including 3 lines were studied by PCR-RFLP method,and its genetic effects on carcass traits were researched. The results showed that 2 genotypes (MN and NN) in G(2100)A locus were identified by Bsh1236 I and 3 genotypes (AA, AB and BB) in G(2109)A locus were identified by Msp I, and 5 genotypes were emerged while com-analyzing 2 loci. The chi2 test indicated genotype frequencies had no significant deviation (P > 0.05) among lines. The analysis of variance showed that the different genotypes had significant deviation (P <0.01 or P < 0.05) in carcass percent. The multiple comparisons were made. The abdominal fat weight and carcass percent of heterozygosis MN were significantly higher (P<0.05) than that of mutant NN,and the breast muscle weight and breast muscle percent of heterozygosis AB were significantly higher (P < 0.01 or P<0.05) than that of AA individuals. In addition,the abdominal fat weight and abdominal fat percent of AA individuals were significantly higher (P<0.01) than that of mutant BB individuals,but BB individuals were significantly lower (P<0.05) than AA and AB individuals in leg muscle weight trait. The abdominal fat weight,abdominal fat percent and breast muscle percent of genotype NA/MA individuals were significantly higher or lower (P<0.01) than those in other genotype individuals while com-analyzing 2 loci.
Analysis of microsatellite markers with the milk product traits in Simmental
西门塔尔牛产奶性状的微卫星标记分析

FANG Xiao-min,XU Shang-zhong,ZHANG Ying-han,XU Ning-ying,
方晓敏
,许尚忠,张英汉,徐宁迎

遗传 , 2005,
Abstract: 12 microsatellite markers from 4 chromosomes were chosen to analyze the effect on 5 milk production traits (including fat, lactoprotein, lactose, dry matter content and somatic cell number) of 150 cows from a 6-male-line Simmental breeding core group. Results showed that the 12 microsatellite markers were highly polymorphic and their PIC (polymorphism information contents) were over 0.60, and the marker with the highest PIC (0.85) was ILST093. The heterozygosities were among 0.64 and 0.86. Effects of 12 microsatellite loci on milk production traits were analyzed. Results showed that ILST093 had a significant effect on somatic cell number (P<0.05). Effects of BMS711 on fat ratio and of BMS1905 on lactose both reached a significant level (P<0.05), BM6438 on milk production traits had no significant effect.
Effects of microsatellite in the regulatory region of IGF1 on growth traits in Jinhua swine
IGF1调控区微卫星座位对金华猪生长性能的影响

ZHAO Xiao-Feng,XU Ning-Ying,HU Xiao-Xiang,LI Ning,
赵晓枫
,徐宁迎,胡晓湘,李宁

遗传 , 2007,
Abstract: Insulin-like growth factor 1(IGF1) and its associated binding proteins and transmembrane receptors(IGFR) play an important role in the physiologic process of mammalian growth.The objectives of present work were to estimate the effects of microsatellite markers located in the 5'-regulatory region of the IGF1 on birth weight(BW),weaning weight(WW),weight at the 120th day,the 180th day and litter weight at birth(LWB) by the least square method in Jinhua pig.Significant effect was found for IGF1 genotype on BW(P<0.05),with positive effects associated with the 286/286 geno-type,and 280/286 genotype on LWB in second parity(P<0.05).Furthermore,according to analysis of allele average sub-stitution effect,alleles 274 bp and 286 bp was favourable for BW increase,allele 280 bp was favourable for LWB increase in the second parity.By correlation analysis,total number of birth,number of birth alive and LWB of the second parity in jin hua pig had highly significant correlation(P<0.01),therefore increasing LWB of the second parity could improve litter performance of Jinhua pig.
Polymorphism in 5' Regulatory Region of the Porcine Fat Mass and Obesity Associated (FTO) Gene is Associated with Intramuscular Fat Content in a Jinhua x Pietrain F2 Reference Population
Zhang Li-Fan,Miao Xiu-Ting,Hua Xu-Chuan,Jiang Xiao-Ling,Lu Yuan-Peng,Xu Ning-Ying
Journal of Animal and Veterinary Advances , 2012,
Abstract: As a newly described candidate gene in obesity, FTO gene showed a strong and highly significant association with the obesity-related traits in various human populations. It has been suggested that FTO gene play a key role in the regulation of energy balance and feed intake. Here we sequenced the -2.0 kb of the 5' flanking region of the porcine FTO gene, 7 SNPs were detected in this region and genotyped on the Jinhua x Pietrain F2 reference population. Using a gene-wide haplotype-tagging approach, three tag SNPs were examined. The SNPs of g -1191 A>G had significant associations with Intramuscular Fat (IMF) content (p<0.05), but not with the Average Backfat Thickness (ABF), Leaf Fat weight (LF) or Average Daily Gain (ADG). Additionally, allele frequencies of the g -1191A>G mutation were studied in 6 pig breeds and the G allele was mainly occurred in Chinese native pig breeds. These results provided the solid evidence that FTO gene was associated with the intramuscular fat deposition in pigs.
Hypoxic Adaptation and Myoglobin Expression in Heart Tissue of Tibet Chicken Embryo
Zhang Li-Fan,Liu Chong,Bao Hai-Gang,Zhao Chun-Jiang,Lian Lin-Sheng,Xu Ning-Ying,Wu Chang-Xin
Journal of Animal and Veterinary Advances , 2012, DOI: 10.3923/javaa.2010.529.534
Abstract: Myoglobin (Mb) is a classical member of the globin family and plays an important role in the oxygen transportation or storage. As a unique native chicken breed in high altitude, Tibet chicken has the good adaptation to hypoxia. Here we present the first detailed analysis of Mb expression on hypoxic adaptability in chicken heart. In the present study, fertile eggs of Tibet chicken, Shouguang chicken and Silky chicken were exposed to sustained hypoxia (13% O2) and normoxia (21% O2). Chicken embryo hearts were collected on days 16 and 20 of incubation to examine the effect of hypoxia on Mb. The results showed that there is no significant difference in content or expression levels of Mb among the three chicken breeds in the normoxic environment. Tibet chicken embryos had the heaviest heart weight among these chicken breeds and the Mb content of all chicken breeds had increased in hypoxia comparing with that in normoxia. Under the hypoxic environment, Mb mRNA levels of Tibet chicken were lower than that of Shouguang and Silky chicken, indicating that the hypoxic degree between Tibet chicken and other lowland chicken was different. The smaller changes of Mb content and expression levels in hypoxia in Tibet chicken embryo suggests Tibet chicken had the better hypoxic adaptation ability in utilizing oxygen in heart tissue. The results showed that Mb is up-regulated by hypoxia and may play an important role in mediating heart hypoxic adaptation.
Castration Modulates Leptin and its Receptor in the Hypothalamus from Male Pigs
Cai Zhao-Wei,Zhao Xiao-Feng,Yao Yu-Chang,Jiang Xiao-Ling,Zhang Li-Fan,*Xu Ning-Ying,Wu Chang-Xing
Journal of Animal and Veterinary Advances , 2012, DOI: 10.3923/javaa.2010.1696.1701
Abstract: The aim of the present study was to investigate the effects of castration on the gene expression of leptin and leptin receptor in the hypothalamus from male pigs. Sixteen pairs of pigs were used in our experiment. Each pair was composed of two male full sibs, one of which was castrated at 35 days old and the other remained intact. Eight pairs of pigs were slaughtered at 147 and 210 days old, respectively. Boars weighed more than barrows at 210 days old. However, barrows ate more feed and showed higher carcass fat weight, leaf fat weight and average back fat thickness at 147 and 210 days old. Higher serum leptin but lower testosterone concentration was found in castrated pigs as compared to intact pigs. Castration induced an increase in Ob mRNA in both subcutaneous fat and leaf fat tissue in male pigs. However, there were no differences in hypothalamic expression of Ob-Rb between barrows and boars. These results suggest that castration may influence leptin sensitivity in male pigs.
Effect of SNP in the exon 8 of SIM1 gene on backfat thickness in pigs
SIM1基因第8外显子的SNP对猪背膘厚的影响

GUO Xiao-Ling,CHEN Zhe,ZHAO Xiao-Feng,XU Ning-Ying,
郭晓令
,陈哲,赵晓枫,徐宁迎

遗传 , 2008,
Abstract: SNP in exon 8 of the Single-minded 1 (SIM1) gene was detected using PCR-SSCP in 169 pigs of 6 pig breeds including Yorkshire, Duroc, Pietrain, Landrace, Jiaxinghei and Jinhua. The results showed three genotypes (CC, CT, TT) were found and their frequencies between domestic and foreign breeds were different. Only one genotype TT was found in Jiaxinghei and Jinhua pigs, but three genotypes were detected in each foreign breed. The effects of this SNP on backfat thickness in Landrace, Yorkshire and Duroc were estimated using least square method. The homozygote pigs had thicker backfat than the heterozygote ones. The significant effect of various genotypes was found in foreign breeds (P < 0.05). SIM1 had different effects on backfat thickness of different points.
Mapping RYR1,PIT1 and PRKAG3 using a commercial porcine population as a reference
用商品猪群定位RYR1、PIT1和PRKAG3

GUO Xiao-ling,YIN Zhao-zheng,XU Ning-ying,Kalm Ernst,
郭晓令
,尹兆正,徐宁迎,Kalm Ernst

浙江大学学报(农业与生命科学版) , 2005,
Abstract: 利用一个由汉普夏、皮特兰猪等5品种杂交商品群建立了参考家系,采用微卫星标记构建连锁图谱的方法对分别位于6、13、15号染色体的3个基因RYR1、PIT1、PRKAG3进行了定位.结果表明RYR1位于6号染色体的S0087和Sw316之间,PIT1位于13号染色体的Sw225和Swl056之间,PRKAG3位于15号染色体的Sw946和Sw906之间,与已发表的结果基本一致.为下一步分析这3个基因对经济性状的影响奠定了基础.
Canonical correlation analysis of main breeding traits for Landrace
长白猪主要选育性状间的典型相关分析

XU Ning-ying,WANG Xian-ming,CAO Xiao-ying,WANG Song-jun,
徐宁迎
,王先明,曹小英,王松均

浙江大学学报(农业与生命科学版) , 2000,
Abstract: The analysis of canonical correlation for 14 traits in 3 groups was carried out in the study. The growth and development traits composed of 4 traits, body size 6 traits and fat thickness and appearance 4 traits. The results showed that the first and second coefficients of canonical correlation for the growth and development with the body size, as well as the growth and development with the fat thickness and appearance, was highly significance. The canonical correlation coefficients were 0.647 8 and 0.353 1 with 0.925 and 0.241 7, they represented 96.52% and 99.9% respectively for the total correlation between 2 groups. It was only the first coefficients of canonical correlation highly significance between the body sizes and the fat thickness with appearance, it was 0.328 7 and expressed about 75.59% for the total correlation. The results also showed that the body weights for 2 months and end of the test, chest circumference, ham circumference, back fat thickness and adjusted back fat thickness were the main traits in the study.
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