oalib

Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99

Submit

Any time

2019 ( 160 )

2018 ( 1210 )

2017 ( 1073 )

2016 ( 1096 )

Custom range...

Search Results: 1 - 10 of 78303 matches for " XinWen Chen "
All listed articles are free for downloading (OA Articles)
Page 1 /78303
Display every page Item
Non-abelian Hodge theory for algebraic curves in characteristic p
Tsao-Hsien Chen,Xinwen Zhu
Mathematics , 2013,
Abstract: Let G be a reductive group over an algebraically closed field of positive characteristic. Let C be a smooth projective curve over k. We give a description of the moduli space of flat G-bundles in terms of the moduli space of G-Higgs bundles over the Frobenius twist C' of C. This description can be regarded as the non-abelian Hodge theory for curves in positive characteristic.
Geometric Langlands in prime characteristic
Tsao-Hsien Chen,Xinwen Zhu
Mathematics , 2014,
Abstract: Let $G$ be a semisimple algebraic group over an algebraically closed field $k$, whose characteristic is positive and does not divide the order of the Weyl group of $G$, and let $\breve G$ be its Langlands dual group over $k$. Let $C$ be a smooth projective curve over $k$. Denote by $\Bun_G$ the moduli stack of $G$-bundles on $C$ and $ \Loc_{\breve G}$ the moduli stack of $\breve G$-local systems on $C$. Let $D_{\Bun_G}$ be the sheaf of crystalline differential operators on $\Bun_G$. In this paper we construct an equivalence between the bounded derived category $D^b(\on{QCoh}(\Loc_{\breve G}^0))$ of quasi-coherent sheaves on some open subset $\Loc_{\breve G}^0\subset\Loc_{\breve G}$ and bounded derived category $D^b(D_{\Bun_G}^0\on{-mod})$ of modules over some localization $D_{\Bun_G}^0$ of $D_{\Bun_G}$. This generalizes the work of Bezrukavnikov-Braverman in the $\GL_n$ case.
Hepatitis C Virus Induced a Novel Apoptosis-Like Death of Pancreatic Beta Cells through a Caspase 3-Dependent Pathway
Qian Wang, Jizheng Chen, Yun Wang, Xiao Han, Xinwen Chen
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0038522
Abstract: Epidemiological and experimental studies have suggested that Hepatitis C virus (HCV) infection is associated with the development of type 2 diabetes. Pancreatic beta cell failure is central to the progression of type 2 diabetes. Using virus infection system, we investigate the influence of HCV infection on the fate of the insulinoma cell line, MIN6. Our experiments demonstrate that the HCV virion itself is indispensable and has a dose- and time-dependent cytopathic effect on the cells. HCV infection inhibits cell proliferation and induces death of MIN6 cells with apoptotic characteristics, including cell surface exposure of phosphatidylserine, decreased mitochondrial membrane potential, activation of caspase 3 and poly (ADP-ribose) polymerase, and DNA fragmentation in the nucleus. However, the fact that HCV-infected cells exhibit a dilated, low-density nucleus with intact plasma and nuclear membrane indicates that a novel apoptosis-like death occurs. HCV infection also causes endoplasmic reticulum (ER) stress. Further, HCV RNA replication was detected in MIN6 cells, although the infection efficiency is very low and no progeny virus particle generates. Taken together, our data suggest that HCV infection induces death of pancreatic beta cells through an ER stress-involved, caspase 3-dependent, special pathway.
Remote Quantum-Information Concentration: Reversal of Ancilla-Free Phase-Covariant Telecloning  [PDF]
Xinwen Wang, Shiqing Tang
Open Journal of Microphysics (OJM) , 2013, DOI: 10.4236/ojm.2013.31004
Abstract:

Telecloning and its reverse process, referred to as remote quantum-information concentration (RQIC), have been attracting considerable interest because of their potential applications in quantum-information processing. The previous RQIC protocols were focused on the reverse process of the optimal universal telecloning. We here study the reverse process of ancilla-free phase-covariant telecloning (AFPCT). It is shown that the quantum information originally distributed into two spatially separated qubits from a single qubit via the optimal AFPCT procedure can be remotely concentrated back to a single qubit with a certain probability by using an asymmetric W state as the quantum channel.

Cloning the interferon regulatory factor 1 gene in lungfish (Protopterus annectens) and its molecular evolution among sarcopterygians
XiaoNi Gan,DengQiang Wang,XuZhen Wang,XinWen Chen
Chinese Science Bulletin , 2011, DOI: 10.1007/s11434-011-4455-6
Abstract: Sarcopterygians is an important vertebrate clade that includes crossopterygians and tetrapods. Crossopterygians are lobe-finned fish that include lungfish and coelacanths. Tetrapods include amphibians, reptiles, avians and mammals. To compare the interferon regulatory factor 1 (irf-1) gene structure and to explore phylogenetic relationships among sarcopterygians, we cloned the cDNA sequence of irf-1 from lungfish and compared it with irf-1 orthologs in other sarcopterygian species. The lungfish is a primitive sarcopterygian that occupies a very important position in vertebrate phylogeny. Interferon regulatory factors (IRFs) are a family of proteins involved in innate immunity. To date, 11 IRF family members have been reported. All IRFs share homology in the first 115 amino acids, which encompasses a DNA binding domain containing a characteristic repeat of 5 tryptophan residues separated by 10–18 amino acids. IRF-1 and IRF-2 were the first members of this family to be reported and they have a very important role in innate immunity. However, studies of the irf-1 and irf-2 genes are mostly confined to mammals; very few non-mammalian irf-1 genes have been reported. Consistent with the irf-1 gene sequences already published, the first 345 nucleotides of lungfish irf-1 are highly conserved. At the carboxyl terminal a C-terminal transactivating region motif and an interferon associated domain (IAD2) were identified. 417 million years separate the present from the closest common ancestor of lungfish and tetrapods; however, the irf-1 genes among sarcopterygians are highly conserved and have very obvious phylogenetic relationships. Also the interrelationship tree of sarcopterygians, based on IRF-1 amino acid sequences, is identical with trees produced using other data, such as morphological characteristics or mitochondrial gene sequences.
Group I but not Group II NPV induces antiviral effects in mammalian cells
Changyong Liang,Jianhua Song,Zhihong Hu,Xinwen Chen
Science China Life Sciences , 2006, DOI: 10.1007/s11427-006-2023-0
Abstract: Nucleopolyhedrovirus (NPV) is divided into Group I and Group II based on the phylogenetic analysis. It has been reported that Group I NPVs such as Autographa californica multiple NPV (AcMNPV) can transduce mammalian cells, while Group II NPVs such as Helicoverpa armigera single NPV (HaSNPV) cannot. Here we report that AcMNPV was capable of stimulating antiviral activity in human hepatoma cells (SMMC-7721) manifested by inhibition of Vesicular Stomatitis virus (VSV) replication. In contrast, the HaSNPV and the Spodoptera exigua multiple NPV (SeMNPV) of group II had no inhibitory effect on VSV. Recombinant AcMNPV was shown to induce interferons alpha/beta even in the absence of transgene expression in human SMMC-7721 cells, while it mediated transgene expression in BHK and L929 mammalian cells without an ensuing antiviral activity.
An efficient method of constructing homologous recom binant baculovirus with PCR-amplified fragments
Songwang Hou,Xinwen Chen,Hanzhong Wang,Zhihong Hu
Science China Life Sciences , 2003, DOI: 10.1007/BF03192586
Abstract: This paper describes a rapid method of constructing homologous recombinant baculovirus inE. coli with PCR-amplified fragments. By using this method, the traditional steps of constructing transfer vector are omitted. The method is based on phage λ red system which can promote the recombination between the homologous fragments with the length above 36 bp. Taking HaSNPV as an example, this paper describes the rapid recombination process by using chloramphenicol resistance gene (Cm R ) to replaceorf135 in HaSNPV genome. A pair of primers with length of 60 bp was synthesized, in which 40 bp was homologous to the each end sequence oforf135, and the rest 20 bp was homologous to the each end sequence ofCm R . By using these primers, a linear fragment containing the completeCm R gene between 40 bp of homologous arms oforf135 was generated by PCR with the plasmid pKD3 which containsCm R as the template. By transforming the linear fragment into theE. coli containing the bacterial artificial chromosome of HaSNPV and with the help of a plasmid expressing λ recombinase, the recombinants on which the homologue replacement had taken place were selected by chloramphenicol resistance. This method greatly shortens the process of constructing recombinant baculovirus since the process was performed inE. coli and does not need to construct transfer vectors. It can be further used for gene replacement and gene deletion of other large viral genomes.
MEASUREMENT EQUIVALENCE:CONCEPTIOIN AND TEST CONDITIONS
测量等价性的概念及其判定条件

Bai Xinwen,Chen Yiwen,
白新文
,陈毅文

心理科学进展 , 2004,
Abstract: Equivalent measurement is obtained when the relations between observed test scores and the latent attribute measured by the test are identical across subpopulations. In particular, individuals with equal standings on the latent trait, but sampled from different subpopulations, should have the same expected observed score. Measurement equivalence serves as the precondition to conducting substantive cross-group difference comparisons. This article introduces the conception of measurement equivalence, the brief history of the research, and the necessity of measurement equivalence; then lists the conditions of measurement equivalence within the framework of structural equation modeling (SEM); also presents the goodness-of-fit indices which are used to justify the goodness of fit of the models.
Group I but not Group II NPV induces antiviral effects in mammalian cells
LIANG Changyong,SONG Jianhua,HU Zhihong &,CHEN Xinwen,

中国科学C辑(英文版) , 2006,
Abstract: Nucleopolyhedrovirus(NPV) is divided into Group I and Group II based on the phy-logenetic analysis.It has been reported that Group I NPVs such as Autographa californica multiple NPV(AcMNPV) can transduce mammalian cells,while Group II NPVs such as Helicoverpa armigera single NPV(HaSNPV) cannot.Here we report that AcMNPV was capable of stimulating antiviral ac-tivity in human hepatoma cells(SMMC-7721) manifested by inhibition of Vesicular Stomatitis virus(VSV) replication.In contrast,the HaSNPV and the Spodoptera exigua multiple NPV(SeMNPV) of group II had no inhibitory effect on VSV.Recombinant AcMNPV was shown to induce interferons al-pha/beta even in the absence of transgene expression in human SMMC-7721 cells,while it mediated transgene expression in BHK and L929 mammalian cells without an ensuing antiviral activity.
Reliability of Power System Integrated with Wind Generation Considering Carbon Tax  [PDF]
Xinwen Ni, Kwok Lun Lo
World Journal of Engineering and Technology (WJET) , 2016, DOI: 10.4236/wjet.2016.43D007
Abstract:
This paper proposes a method to evaluate the reliability of power system with different capacities of wind power while considering carbon tax. The proposed method is a hybrid approach which combines Frequency and Duration (F&D) method and Monte Carlo Simulation (MCS) method. MCS method is used to achieve a model to simulate the random status of power system. Also, the proposed method is applied on the IEEE 14-bus test system to investigate the effects of integrating different capacities of wind energy to the reliability of power system with considering carbon tax.
Page 1 /78303
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.