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Search Results: 1 - 10 of 78767 matches for " Xiao-lin Pan "
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An Overview of Personal Credit Scoring: Techniques and Future Work  [PDF]
Xiao-Lin Li, Yu Zhong
International Journal of Intelligence Science (IJIS) , 2012, DOI: 10.4236/ijis.2012.224024
Abstract: Personal credit scoring is the application of financial risk forecasting. It becomes an even important task as financial institutions have been experiencing serious competition and challenges. In this paper, the techniques used for credit scoring are summarized and classified and the new method—ensemble learning model is introduced. This article also discusses some problems in current study. It points out that changing the focus from static credit scoring to dynamic behavioral scoring and maximizing revenue by decreasing the Type I and Type II error are two issues in current study. It also suggested that more complex models cannot always been applied to actual situation. Therefore, how to use the assessment models widely and improve the prediction accuracy is the main task for future research.
The Heparan and Heparin Metabolism Pathway is Involved in Regulation of Fatty Acid Composition
Zhihua Jiang, Jennifer J. Michal, Xiao-Lin Wu, Zengxiang Pan, Michael D. MacNeil
International Journal of Biological Sciences , 2011,
Abstract: Six genes involved in the heparan sulfate and heparin metabolism pathway, DSEL (dermatan sulfate epimerase-like), EXTL1 (exostoses (multiple)-like 1), HS6ST1 (heparan sulfate 6-O-sulfotransferase 1), HS6ST3 (heparan sulfate 6-O-sulfotransferase 3), NDST3 (N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3), and SULT1A1 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1), were investigated for their associations with muscle lipid composition using cattle as a model organism. Nineteen single nucleotide polymorphisms (SNPs)/multiple nucleotide length polymorphisms (MNLPs) were identified in five of these six genes. Six of these mutations were then genotyped on 246 Wagyu x Limousin F2 animals, which were measured for 5 carcass, 6 eating quality and 8 fatty acid composition traits. Association analysis revealed that DSEL, EXTL1 and HS6ST1 significantly affected two stearoyl-CoA desaturase activity indices, the amount of conjugated linoleic acid (CLA), and the relative amount of saturated fatty acids (SFA) and monounsaturated fatty acids (MUFA) in skeletal muscle (P<0.05). In particular, HS6ST1 joined our previously reported SCD1 and UQCRC1 genes to form a three gene network for one of the stearoyl-CoA desaturase activity indices. These results provide evidence that genes involved in heparan sulfate and heparin metabolism are also involved in regulation of lipid metabolism in bovine muscle. Whether the SNPs affected heparan sulfate proteoglycan structure is unknown and warrants further investigation.
Mineral structure and crystal morphologies of high-iron hydrargillite
Hui-bin Yang,Feng-qin Liu,Xiao-lin Pan
- , 2018, DOI: https://doi.org/10.1007/s12613-018-1597-4
Abstract: Various characterization methods, including scanning electron microscopy, transmission electron microscopy, energy-dispersive X-ray spectroscopy, Brunauer–Emmett–Teller surface-area measurements, thermogravimetry–differential scanning calorimetry, X-ray diffraction, and infrared spectroscopy, were used to study the mineral structure and surface characteristics of high-iron hydrargillite. Gibbsite, goethite, and hematite were found to be the main mineral components of hydrargillite, whereas the goethite and hematite were closely clad to the surface of the multilayer gibbsite crystals. Compared with the synthetic gibbsite, the hydrargillite contained more structural micropores generated by the mineral evolution during the mineralization process. The gibbsite in hydrargillite contained less crystal water compared with the synthetic gibbsite, and it was a typical polymorphic structure. The isomorphous substitution of Al and Fe was observed in goethite. The dissolution-controlling step of hydrargillite was the ionic diffusion speed because of the goethite and hematite that closely covered and encapsulated the gibbsite crystals.
The Reverse Cholesterol Transport Pathway Improves Understanding of Genetic Networks for Fat Deposition and Muscle Growth in Beef Cattle
Tyler F. Daniels,Xiao-Lin Wu,Zengxiang Pan,Jennifer J. Michal,Raymond W. Wright Jr,Karen M. Killinger,Michael D. MacNeil,Zhihua Jiang
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0015203
Abstract: In the present study, thirteen genes involved in the reverse cholesterol transport (RCT) pathway were investigated for their associations with three fat depositions, eight fatty acid compositions and two growth-related phenotypes in a Wagyu x Limousin reference population, including 6 F1 bulls, 113 F1 dams, and 246 F2 progeny. A total of 37 amplicons were used to screen single nucleotide polymorphisms (SNPs) on 6 F1 bulls. Among 36 SNPs detected in 11 of these 13 genes, 19 were selected for genotyping by the Sequenom assay design on all F2 progeny. Single-marker analysis revealed seven SNPs in ATP binding cassette A1, apolipoproteins A1, B and E, phospholipid transfer protein and paraoxinase 1 genes significantly associated with nine phenotypes (P<0.05). Previously, we reported genetic networks associated with 19 complex phenotypes based on a total of 138 genetic polymorphisms derived from 71 known functional genes. Therefore, after Bonferroni correction, these significant (adjusted P<0.05) and suggestive (adjusted P<0.10) associations were then used to identify genetic networks related to the RCT pathway. Multiple-marker analysis suggested possible genetic networks involving the RCT pathway for kidney-pelvic-heart fat percentage, rib-eye area, and subcutaneous fat depth phenotypes with markers derived from paraoxinase 1, apolipoproteins A1 and E, respectively. The present study confirmed that genes involved in cholesterol homeostasis are useful targets for investigating obesity in humans as well as for improving meat quality phenotypes in a livestock production.
Treatment adherence among sputum smear-positive pulmonary tuberculosis patients in mountainous areas in China
Song Yao, Wen-Hui Huang, Susan van den Hof, Shu-Min Yang, Xiao-Lin Wang, Wei Chen, Xue-Hui Fang, Hai-Feng Pan
BMC Health Services Research , 2011, DOI: 10.1186/1472-6963-11-341
Abstract: In each of the five provinces, all counties with > 80% mountainous area were stratified into three groups according to their gross domestic product. In each stratum, one county was randomly sampled. Study subjects were sampled from all smear positive TB cases registered in 2007 in the target counties. TB patients, village doctors, county doctors and directors of the TB prevention and control institutes were interviewed. Insufficient medication adherence was defined as taking less than 90% of anti-TB drug doses prescribed. Insufficient re-examination adherence was defined as having less than the recommended three sputum smear examinations during the treatment course.A minority of patients took drugs under direct observation: on average 29% during the intensive phase of treatment. In total, 524 TB patients were included, of whom 49 (9.4%) took less than 90% of all doses prescribed and 92 (17.6%) did not have all sputum smear examinations, with substantial variations between the provinces. In multivariable analysis, no direct observation of treatment during the intensive phase and the presence of adverse events were associated both with insufficient medication adherence and insufficient re-examination adherence. Overall, 79% of patients were adherent both to treatment and re-examinations.In these remote and poor areas of China, the TB control program is not fully functioning according to the guidelines. The majority of patients are not treated under direct observation, while direct observation by health care staff was associated with better adherence, both to drug therapy and re-examinations. Insufficient adherence increases the risk of unsuccessful treatment outcomes and development of drug resistance. Measures should be taken urgently in these areas to strengthen implementation of the international Stop TB strategy.Adherence, or compliance, refers to the extent patients correctly follow medical advice [1]. Adherence refers both to taking drugs according to prescripti
Radiation-inducible promoter mediated PUMA Gene in the the treatment of Tca8113  [PDF]
Dong-Sheng Yu, Wei Zhao, Jia-xian Luo, Bing Liu, Xiao-Lin Wu
Open Journal of Stomatology (OJST) , 2011, DOI: 10.4236/ojst.2011.14030
Abstract: Objective: The aim of this study is to explore the therapeutic effect of the PUMA gene mediated by ra- diation-inducible promoters in the treatment of ton- gue squamous cell carcinoma. Methods: Recombi- nant pcDNA3.1 (+)/E-PUMA was constructed, in which the PUMA gene was mediated by a synthetic radiation inducible promoter. The recombined plas-mids were transfected into the Tca8113 cell and xeno- grafts of human tongue squamous carcinoma in na- ked mice respectively. After 24 h, the tumors were tr- eated with 3 Gy of irradiation to upregulate the PU- MA gene expression. PUMA mRNA was detected by RT-PCR. Proliferating cell nuclear antigen (PCNA) and apoptosis were detected by immunohistochemi- cal method and in situ end-labeling (ISEL) respecti- vely. The data were analyzed using the SPSS11.0 soft- ware package for chi-square test. RESULTS: Com-pared with the control group, the comparative survi- val rate of Tca8113 cells in the PUMA/IR group was markedly decreased and the xenografts were signify- cantly suppressed. Up-regulation of PUMA gene ex- pression was observed in the Tca8113 cells and in the xenografts after irradiation. The apoptosis indices of the Tca8113 cells and xenograft with irradiation were markedly higher than those without irradiation. At the same time, the proliferation indices of the Tca- 8113 cells and xenografts with irradiation were mark- edly lower than those without irradiation. Conclu- sions: radiation-induc ible promoters can serve as molecular switches to improve the expression of PU- MA gene in tongue squamous cell carcinoma both in vivo and in vitro. Low-dose induction radiation can significantly improve therapeutic efficiency.
Mathematical analysis of effects of morphometric attributes on body weight for Penaeus vannamei

LIU Xiao-Lin,

生态学报 , 2004,
Abstract: The effects of morphometric attributes on body weight for Penaeus vannamei were analyzed. Data for this study were collected from six-month-old 176 Penaeus vannamei in Banqiao Village of Dongfang City , Hainan Province. The body length ( X _1), carapace length ( X _2), carapace width ( X _3), carapace height ( X _4), number of upper frontal eminence spine ( X _5), number of lower frontal eminence spine ( X _6), tail length ( X _7) and body weight (Y) were measured. The correlation coefficients among the attributes were calculated. Tail length was eliminated from the variable data set because it was co-linear with body length ( X _1) and carapace length ( X _2). The first 6 morphometric attributes( X _1~ X _6) were used as independent variables, and body weight( Y ) was used as a dependent variable for path analysis. Path coefficients ( Pi ), determination coefficients ( di) and correlation index ( R ~2) were calculated in path analysis. The results showed that all five correlation coefficients between each morphometric attribute and the weight (0.9446, 0.9262, 0.9102, 0.7923, 0.933) achieved very significant difference ( P <0.01) levels. The path coefficient analysis revealed a truthful relationship between the independent variables and the dependent variable. The path coefficients( Pi ) of the body length ( X _1), carapace length ( X _2), carapace width ( X _3) and number of lower frontal eminence spine ( X _6) to the body weight have all reached a level of significance. These attributes are very indicative of determining the body weight, among them body length ( X _1) weighted the most ( P _1=0.428) to the body weight, it is a key effective factor, carapace length ( X _2) and carapace width ( X _3) weighted the second and third ( P _2=0.2902, P _3=0.2453, significant indirect effect 0.6145, 0.6408 respectively). The number of lower frontal eminence spine ( X _6), carapace height ( X _4), number of upper frontal eminence spine ( X _5), and tail length ( X _7) have insignificant direct effect on the body weight and were neglected. The diversification of determination coefficients ( d_i ) is consistent with that of path coefficients( P_i ). Judging from the result of high correlation index ( R ~2=0.921), the main variables ( X _1, X _2, X _3, X _6) have been selected. The multiple regression equation of the body length ( X _1), carapace length ( X _2), carapace width ( X _3) and number of lower frontal eminence spine ( X _6) to the body weight is obtained to estimate body weight. the regression intercept and partial regression coefficients of the equation are -17.994, 1.477, 4.159, 6.197, and 0.4757. This paper provide a theoretical tool to measure breeding shrimps in aquaculture.
Fast reconstruction of wave-field propagator in wave-equation depth migration

LU Xiao-lin,

地球物理学进展 , 2005,
Abstract: Computer's capacity and memory are key factors in pre-stack depth migration based on wave-equation. Nowadays, pre-stack depth migration comes into use in industrial production along with the appearance of Beowulf PC-clusters, but it still takes much longer time than traditional post-stack migration. In this paper, we smooth the propagator with cubic spline function then reconstruct the propagator adopting sample function. Thus we can reduce the use of computer's memory and in the meantime ensure accuracy, so that the whole dat-processing time is shortened.
Genetic co-adaptability among structural genes under the condition of genetic disequilibrium

PAN Qing-Jie,LI Xiao-Lin,MIN Ling-Jiang,SHEN Wei,Liu Di,

遗传 , 2007,
Abstract: Genetic co-adaptability of colony gene bank is formed in the process of system evolvement, and it is a part of the attribute of gene bank, just as the gene frequency of every locus. With the genetic co-adaptability of loci combination under the condition of genetic disequilibrium, the genesis evolution and the system status of colony could be analyzed; through the study of genetic co-adaptability, the veracity of the economy character mark could be improved. We summa- rized about the concept, the basic and the actuality of genetic co-adaptability.
Mass and axial charge of heavy baryons
Nan Jiang,Xiao-Lin Chen,Shi-Lin Zhu
Physics , 2014, DOI: 10.1103/PhysRevD.90.074011
Abstract: We investigate the antitriplet and sextet heavy baryon systems with $J^P= \frac{1}{2}^+, \frac{3}{2}^+$ in the framework of the heavy baryon chiral perturbation theory. We first calculate the chiral corrections to the heavy baryon mass from the SU(3) flavor breaking effect up to $O(p^3)$. Then we extend the same formalism to calculate the chiral corrections to the axial charges of the heavy baryons in the isospin symmetry limit.
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