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Search Results: 1 - 10 of 125816 matches for " Xiao-hua Liu "
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Iteration and Iterative Roots of Fractional Polynomial Function
Xiao-hua Liu
International Journal of Mathematics and Mathematical Sciences , 2012, DOI: 10.1155/2012/365956
Abstract: Iteration is involved in the fields of dynamical systems and numerical computation and so forth. The computation of iteration is difficult for general functions (even for some simple functions such as linear fractional functions). In this paper, we discuss fractional polynomial function and use the method of conjugate similitude to obtain its expression of general iterate of order n under two different conditions. Furthermore, we also give iterative roots of order n for the function under two different conditions.
THE HIRIART-URRUTY PROBLEM ANDPROPERTIES OF THE CLARKEGENERALIZED GRADIENT
Hiriart—Urruty问题与Clarke广义梯度的若干性质

LIU XIAO-HUA,
刘晓华

系统科学与数学 , 1994,
Abstract: Several necessary and sufficient conditions for the functions satisfying the Hiriarturruty problem are given. We prove that the image set of 6j from a compactsubset is still a compact subset. Under certain conditions, the limit poittts ofntersection set of of (T) and a hyperplane.
Resurrection in A Tale of Two Cities
Ding-yuan LIU,Xiao-hua HOU
Canadian Social Science , 2009,
Abstract: A Tale of Two Cities is one of Dickens’ most important masterpieces and is one of the famous novels taking the French Revolution as its background in British literature. Dickens’ works always convey his deep sympathy for the plebeian and pitilessly reveal the social vices. With A Tale of Two Cities, Charles Dickens asserts his belief in the possibility of resurrection and transformations both on a personal level and a society level. This article, in accordance with the plot of the story and the characters’ personalities as well as the relation between the characters, analyses the specific embodiment of “resurrection” in three main characters with details. By this, the author points out that resurrection is a powerful theme which is applicable outside of the novel’s setting but can be read between the lines. Key Words: Charles Dickens, A Tale of Two Cities, Resurrection, Rebirth Résumé: “Un conte de deux villes” est un des plus importants chefs-d’oeuvre de Dicken , un des contes les plus connus de la littérature anglaise sous le contexte de la Révolution fran aise . Les oeuvres de Dicken montre toujours sa sympathie pour de simples gens , et révèlent sans merci les vices sociaux . Avec “ Un conte de deux villes ” , Charles Dickens affirme sa croyance à la possibilité de la résurrection et de la transformation non seulement au niveau personnel mais aussi au niveau social . Ce texte , en concordance avec l’intrigue de l’histoire , les caractères des personages , ainsi que la relation entre les personnages , analyse de fa on détaillée l’incarnation spécifique de “Résurrection ” dans les trois héros principaux . A travers cela , l’auteur affirme que “Résurrection ” est un thème puissant qui est applicable en dehors du contexte du conte , et peut être lu entre les lignes . Mots clés: Charles Dickens, “Un conte de deux villes”, Résurrection, renaissance
Joint Modeling of Transitional Patterns of Alzheimer's Disease
Wei Liu, Bo Zhang, Zhiwei Zhang, Xiao-Hua Zhou
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0075487
Abstract: While the experimental Alzheimer's drugs recently developed by pharmaceutical companies failed to stop the progression of Alzheimer's disease, clinicians strive to seek clues on how the patients would be when they visit back next year, based upon the patients' current clinical and neuropathologic diagnosis results. This is related to how to precisely identify the transitional patterns of Alzheimer's disease. Due to the complexities of the diagnosis of Alzheimer's disease, the condition of the disease is usually characterized by multiple clinical and neuropathologic measurements, including Clinical Dementia Rating (CDRGLOB), Mini-Mental State Examination (MMSE), a score derived from the clinician judgement on neuropsychological tests (COGSTAT), and Functional Activities Questionnaire (FAQ). In this research article, we investigate a class of novel joint random-effects transition models that are used to simultaneously analyze the transitional patterns of multiple primary measurements of Alzheimer's disease and, at the same time, account for the association between the measurements. The proposed methodology can avoid the bias introduced by ignoring the correlation between primary measurements and can predict subject-specific transitional patterns.
Enhancement of CTLs induced by DCs loaded with ubiquitinated hepatitis B virus core antigen
Jian-Hua Chen,Yong-Sheng Yu,Xiao-Hua Chen,Hong-Hong Liu
World Journal of Gastroenterology , 2012, DOI: 10.3748/wjg.v18.i12.1319
Abstract: AIM: To investigate whether hepatitis B virus (HBV) could induce a hepatitis B virus core antigen (HBcAg)-specific cytotoxic T lymphocyte (CTL) response in vitro by dendritic cells (DCs) transduced with lentiviral vector-encoding ubiquitinated hepatitis B virus core antigen (LV-Ub-HBcAg). METHODS: Recombinant LV-Ub-HBcAg were transfected into highly susceptible 293 T cells to obtain high virus titres. Bone marrow-derived DCs isolated from BALB/c mice were cultured with recombinant granulocyte-macrophage colony-stimulating factor and recombinant interleukin (IL)-4. LV-Ub-HBcAg, lentiviral vector-encoding hepatitis B virus core antigen (LV-HBcAg), lentiviral vector (LV) or lipopolysaccharide were added to induce DC maturation, and the DC phenotypes were analyzed by flow cytometry. The level of IL-12 in the supernatant was detected by enzyme-linked immunosorbent assay (ELISA). T lymphocytes were proliferated using Cell Counting Kit-8. DCs were cultured and induced to mature using different LVs, and co-cultured with allogeneic T cells to detect the secretion levels of IL-2, IL-4, IL-10 and interferon-γ in the supernatants of T cells by ELISA. Intracellular cytokines of proliferative T cells were analyzed by flow cytometry, and specific CTL activity was measured by a lactate dehydrogenase release assay. RESULTS: LV-Ub-HBcAg-induced DCs secreted more IL-12 and upregulated the expression of CD80, CD86 and major histocompatibility class II. DCs sensitised by different LVs effectively promoted cytokine secretion; the levels of IL-2 and interferon-γ induced by LV-Ub-HBcAg were higher than those induced by LV-HBcAg. Compared with LV-HBcAg-transduced DCs, LV-Ub-HBcAg-transduced DCs more efficiently stimulated the proliferation of T lymphocytes and generated HBcAg-specific cytotoxic T lymphocytes. CONCLUSION: LV-Ub-HBcAg effectively induced DC maturation. The mature DCs efficiently induced T cell polarisation to Th1 and generated HBcAg-specific CTLs.
5-(4-Chlorophenoxy)-6-isopropyl-3-phenyl-3H-1,2,3-triazolo[4,5-d]pyrimidin-7(6H)-one
Xiao-Hua Zeng,Xiao-Ling Liu,Shou-Heng Deng,Ping Chen
Acta Crystallographica Section E , 2009, DOI: 10.1107/s160053680903788x
Abstract: In the title compound, C19H16ClN5O2, the triazolopyrimidine ring system is essentially planar, with a maximum displacement of 0.021 (4) , and forms dihedral angles of 1.09 (9) and 87.74 (9)° with the phenyl and benzene rings, respectively. Short intramolecular C—H...O and C—H...N hydrogen-bonding interactions occur within the molecule. In the crystal structure, molecules are linked by intermolecular C—H...O hydrogen bonds into chains parallel to the b axis. In addition, π–π stacking interactions involving the triazole and pyrimidine rings of adjacent molecules are observed, with centroid–centroid distances of 3.600 (3) .
Effects of Drought Stress on Growth of Mulberry (Morus alba L. ) Trees in the Hydro-Fluctuation Belt
HUANG Xiao-hui,YIN Xiao-hua,LIU Yun,LI Jia-xing
Journal of Chongqing Normal University , 2012,
Abstract: "To examine possible effects of soil water conditions in summer in the hydro-fluctuation belt of the Three Gorges Reservoir Area on mulberry, we grew potted mulberry in a greenhouse under three soil water regimes designed to simulate normal irrigation (CK), moderate drought stress (T1) and elevated drought stress (T2). The results showed the following.1) With drought stress increasing, the heights, base diameters, and root surface areas of mulberry trees decreased significantly relative to the corresponding earlier period. The root / shoot ratio increased gradually in the earlier stage, and decreased gradually in the later stage. The specific root area of mulberry trees on the whole increased significantly relative to the corresponding earlier period. 2) With the elongation of treatment time, the growth of mulberry seedlings decreased gradually, and the heights, base diameters, root surface area and root / shoot ratio of the mulberry trees in the three treatment groups increased to different degrees. The specific root area of mulberry trees on the whole decreased gradually. We concluded that under the different degrees of drought stress the growth of mulberry trees would be inhibited, but the plants were also able to adapt to the stress, thereby maintaining physiological and metabolic viability. Biomass appeared to be re-allocated such that water absorption capacity was improved. Accordingly it can be concluded that the mulberry trees demonstrated potential for resisting and tolerating drought stress."
Cancer stem cell subsets and their relationships
Hai-Guang Liu, Chong Chen, Han Yang, Yi-Fei Pan, Xiao-Hua Zhang
Journal of Translational Medicine , 2011, DOI: 10.1186/1479-5876-9-50
Abstract: Cancer is a kind of abnormal tissue that develops the ability of unlimited growth and the resistance to various survival stresses. Recently, accumulating experimental evidence supports that cancer stem cells account for the initiation and progression of cancer, which challenges the classical stochastic model of cancer development[1]. The cancer stem cell model or intrinsic model posits similar differentiation hierarchy such as hematopoietic system, cancer stem cells, cancer transient-amplifying (TA) cells and cancer differentiated cells, which is defined as vertical hierarchy here. Only cancer stem cells or cancer TA cells that reacquire self-renewal property can initiate cancer and progress into more malignant disease. However, in the stochastic model no hierarchy in cancer exists and every single cancer cell has the capacity of initiation and progression. Cancer stem cell hypothesis suggests that targeted therapy to cancer stem cells, not cancer TA cells and cancer differentiated cells, is the best measure to eradicate cancer, because traditional cancer therapies target the cancer TA cells and cancer differentiation cells, but omit cancer stem cells, thus leading to frequent cancer relapse[2].The essential features of cancer stem cells are self-renewal, multi-differentiation and tumorigenic capacity[3]. Cancer stem cells are also able to migrate and resist chemotherapy and radiotherapy. However, cancer stem cells are in constant evolution and these capacities are different among different populations of cancer stem cells. Thus we propose a horizontal hierarchy that comprises precancerous stem cells, primary cancer stem cells, migrating cancer stem cells and chemoradioresistant cancer stem cells (Figure 1). Below we will describe the horizontal hierarchy of cancer stem cells and discuss the relationship among these subsets of cancer stem cells.Cancer cells with features of stem cells were discovered by Rudolf Virchow in the mid-19th century, who found that some can
Characteristic finite element method with moving mesh for nonlinear parabolic integrodifferential equations
对流占优的抛物型积分微分方程的变网格特征有限元法

LIU Xiao-Hua,WANG Tong-Ke,
刘小华
,王同科

数学物理学报(A辑) , 2001,
Abstract: The numerical scheme is established with the method of characteristic finite element with moving mesh.Meanwhile,an optimal L2 norm error estimate is derived.
The electrical characteristics of a 4H-silicon carbide metal-insulator-semiconductor structure with Al2O3 as the gate dielectric

Liu Li,Yang Yin-Tang,Ma Xiao-Hua,

中国物理 B , 2011,
Abstract: A 4H-silicon carbide metal-insulator-semiconductor structure with ultra-thin Al2O3 as the gate dielectric, deposited by atomic layer deposition on the epitaxial layer of a 4H-SiC (0001) 80N-/N+ substrate, has been fabricated. The experimental results indicate that the prepared ultra-thin Al2O3 gate dielectric exhibits good physical and electrical characteristics, including a high breakdown electrical field of 25 MV/cm, excellent interface properties (1×1014 cm-2) and low gate-leakage current (IG = 1 × 10-3 A/cm-2@Eox = 8 MV/cm). Analysis of the current conduction mechanism on the deposited Al2O3 gate dielectric was also systematically performed. The confirmed conduction mechanisms consisted of Fowler-Nordheim (FN) tunneling, the Frenkel-Poole mechanism, direct tunneling and Schottky emission, and the dominant current conduction mechanism depends on the applied electrical field. When the gate leakage current mechanism is dominated by FN tunneling, the barrier height of SiC/Al2O3 is 1.4 eV, which can meet the requirements of silicon carbide metal-insulator-semiconductor transistor devices.
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