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Search Results: 1 - 5 of 5 matches for " Wimol Petkanchanapong "
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A Dominant Clone of Leptospira interrogans Associated with an Outbreak of Human Leptospirosis in Thailand
Janjira Thaipadungpanit,Vanaporn Wuthiekanun,Wirongrong Chierakul,Lee D. Smythe,Wimol Petkanchanapong,Roongrueng Limpaiboon,Apichat Apiwatanaporn,Andrew T. Slack,Yupin Suputtamongkol,Nicholas J. White,Edward J. Feil,Nicholas P. J. Day,Sharon J. Peacock
PLOS Neglected Tropical Diseases , 2007, DOI: 10.1371/journal.pntd.0000056
Abstract: Background A sustained outbreak of leptospirosis occurred in northeast Thailand between 1999 and 2003, the basis for which was unknown. Methods and Findings A prospective study was conducted between 2000 and 2005 to identify patients with leptospirosis presenting to Udon Thani Hospital in northeast Thailand, and to isolate the causative organisms from blood. A multilocus sequence typing scheme was developed to genotype these pathogenic Leptospira. Additional typing was performed for Leptospira isolated from human cases in other Thai provinces over the same period, and from rodents captured in the northeast during 2004. Sequence types (STs) were compared with those of Leptospira drawn from a reference collection. Twelve STs were identified among 101 isolates from patients in Udon Thani. One of these (ST34) accounted for 77 (76%) of isolates. ST34 was Leptospira interrogans, serovar Autumnalis. 86% of human Leptospira isolates from Udon Thani corresponded to ST34 in 2000/2001, but this figure fell to 56% by 2005 as the outbreak waned (p = 0.01). ST34 represented 17/24 (71%) of human isolates from other Thai provinces, and 7/8 (88%) rodent isolates. By contrast, 59 STs were found among 76 reference strains, indicating a much more diverse population genetic structure; ST34 was not identified in this collection. Conclusions Development of an MLST scheme for Leptospira interrogans revealed that a single ecologically successful pathogenic clone of L. interrogans predominated in the rodent population, and was associated with a sustained outbreak of human leptospirosis in Thailand.
Highly Complex Chaotic System with Piecewise Linear Nonlinearity and Compound Structures
Wimol Sanum,Banlue Srisuchinwong
Journal of Computers , 2012, DOI: 10.4304/jcp.7.4.1041-1047
Abstract: A new chaotic system is presented using a single parameter for a two-scroll attractor with high complexity, high chaoticity and widely chaotic range. The system employs two quadratic nonlinearities and two piecewise-linear nonlinearities. The high chaoticity is measured by the the maximum Lyapunov Exponent of 0.429 and the high complexity is measured by the Kaplan-Yorke dimension of 2.3004. Dynamic properties are described in terms of symmetry, a dissipative system, an existence of attractor, equilibria, Jacobian matrices, bifurcations, Poincaroé maps, chaotic waveforms, chaotic spectrum, and forming mechanisms of compound structures.
A low-power low-error single-ended virtually-grounded-drain class AB switched-current memory cell
Wimol San-Um,Banlue Srisuchinwong,Sawasd Tantaratana
Songklanakarin Journal of Science and Technology , 2007,
Abstract: A low-power low-error single-ended virtually-grounded-drain class AB switched-current memory cell is presented. The proposed circuit is relatively simple, based on a basic class AB SI memory cell and a levelshiftedgrounded-gate amplifier. No large differential circuitry and complicated clocking schemes are required. All charge-injection, clock-feedthrough and conduction errors are reduced. As a design exampleusing 0.5-μm CMOS technology, the power consumption is 120 μW at the bias current of 25 μA and supply voltage of 2V. The optimal sampling frequency is at 45MHz. The SNR, SDR and SFDR are 59.7 dB, 61 dB and73 dB, respectively. The total harmonic distortion is less than 0.4%. The transmission gain error and the DC offset current error are less than 0.025 and 0.75 μA, respectively. Demonstrations of a forward differenceintegrator and comparisons to other approaches are also presented.
A novel polymeric herbicide based on phenoxyacetic acid derivatives
Wimol Klaichim,Pairote Klinpituksa,Wae-asae Waehamad
Songklanakarin Journal of Science and Technology , 2009,
Abstract: A novel polymeric herbicide based on phenoxyacetic acid derivatives was prepared by the reaction of epoxidised liquid natural rubber (ELNR) with 2,4-dichlorophenoxyacetic acid (2,4-D) or 2-methyl-4-chlorophenoxyacetic acid(MCPA). The liquid natural rubber (LNR) was firstly obtained from the degradation of natural rubber latex with tert-butyl hydroperoxide and cobalt acetylacetonate at 65oC for 72 hrs. The epoxidised liquid natural rubber was prepared from thereaction of LNR with formic acid and hydrogen peroxide at 50oC for 6 hrs. The reaction of epoxidised liquid natural rubber with 2,4-D or MCPA using triethylamine as a catalyst in toluene was performed at 70, 80, and 90oC for 6, 9, 12, 18, and 24hrs. The polymeric herbicides obtained were characterized and the grafting percentage of 2,4-D or MCPA onto liquid natural rubber were also determined by FT-IR and 1H-NMR spectroscopy. It was found that the grafting percentage increased with increasing amount of reactants, temperature, and reaction time. The release of 2,4-D and MCPA from polymeric herbicides was investigated in pH 6, 7, and 8 buffers at room temperature. The results show that the slowest release of 2,4-D and MCPA was found to be constant at pH 7 for 14 and 10 days, respectively.
Infection with Hepatitis C Virus among HIV-Infected Pregnant Women in Thailand
Denise J. Jamieson,Natapakwa Skunodom,Thanyanan Chaowanachan,Anuvat Roongpisuthipong,William A. Bower,Tawee Chotpitayasunondh,Wendy Bhanich Supapol,Wendi L. Kuhnert,Wimol Siriwasin,Jeffrey Wiener,Sanay Chearskul,Michelle S. McConnell,Nathan Shaffer
Infectious Diseases in Obstetrics and Gynecology , 2008, DOI: 10.1155/2008/840948
Abstract: Objective. The purpose of this study was to describe the epidemiology of coinfection with hepatitis C virus (HCV) and HIV among a cohort of pregnant Thai women. Methods. Samples from 1771 pregnant women enrolled in three vertical transmission of HIV studies in Bangkok, Thailand, were tested for HCV. Results. Among HIV-infected pregnant women, HCV seroprevelance was 3.8% and the active HCV infection rate was 3.0%. Among HIV-uninfected pregnant women, 0.3% were HCV-infected. Intravenous drug use by the woman was the factor most strongly associated with HCV seropositivity. Among 48 infants tested for HCV who were born to HIV/HCV coinfected women, two infants were HCV infected for an HCV transmission rate of 4.2% (95% 0.51–14.25%). Conclusions. HCV seroprevalence and perinatal transmission rates were low among this Thai cohort of HIV-infected pregnant women.
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