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Search Results: 1 - 10 of 54829 matches for " Wen-Ming Hsu "
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Face recognition based on manifold learning and Rényi entropy  [PDF]
Wen-Ming Cao, Ning Li
Natural Science (NS) , 2010, DOI: 10.4236/ns.2010.21007
Abstract: Though manifold learning has been success-fully applied in wide areas, such as data visu-alization, dimension reduction and speech rec-ognition; few researches have been done with the combination of the information theory and the geometrical learning. In this paper, we carry out a bold exploration in this field, raise a new approach on face recognition, the intrinsic α-Rényi entropy of the face image attained from manifold learning is used as the characteristic measure during recognition. The new algorithm is tested on ORL face database, and the ex-periments obtain the satisfying results.
Development of an Indoor Location Based Service Test Bed and Geographic Information System with a Wireless Sensor Network
Shau-Shiun Jan,Li-Ta Hsu,Wen-Ming Tsai
Sensors , 2010, DOI: 10.3390/s100402957
Abstract: In order to provide the seamless navigation and positioning services for indoor environments, an indoor location based service (LBS) test bed is developed to integrate the indoor positioning system and the indoor three-dimensional (3D) geographic information system (GIS). A wireless sensor network (WSN) is used in the developed indoor positioning system. Considering the power consumption, in this paper the ZigBee radio is used as the wireless protocol, and the received signal strength (RSS) fingerprinting positioning method is applied as the primary indoor positioning algorithm. The matching processes of the user location include the nearest neighbor (NN) algorithm, the K-weighted nearest neighbors (KWNN) algorithm, and the probabilistic approach. To enhance the positioning accuracy for the dynamic user, the particle filter is used to improve the positioning performance. As part of this research, a 3D indoor GIS is developed to be used with the indoor positioning system. This involved using the computer-aided design (CAD) software and the virtual reality markup language (VRML) to implement a prototype indoor LBS test bed. Thus, a rapid and practical procedure for constructing a 3D indoor GIS is proposed, and this GIS is easy to update and maintenance for users. The building of the Department of Aeronautics and Astronautics at National Cheng Kung University in Taiwan is used as an example to assess the performance of various algorithms for the indoor positioning system.
Intraoperative Ethanol Treatment as an Adjuvant Therapy of Pterygium Excision
Ko-Hua Chen,Ko-Hua Chen,Ko-Hua Chen,Wen-Ming Hsu
International Journal of Biomedical Science , 2006,
Abstract: Recurrence of pterygium is the main concern for ophthalmic surgeons after the excision of pterygium. To evaluate the efficacy and safety of ethanol treatment during pterygium excision in preventing the recurrence of pterygia, a prospective randomized study was performed of 78 eyes in primary pterygium patients treated by excision. Primary pterygium patients were randomly assigned to ethanol group (38 eyes given intraoperative ethanol) or mitomycin-c (MMC) group (40 eyes given intraoperative MMC). Ethanol (20%) was applied for 60 seconds to the pterygial and its adjacent corneal surfaces before pterygium excision. After excision, the excised site of sclera was soaked with 20% Ethanol for 60 seconds. In group 2, MMC (0.25 mg/ml) was applied for 60 seconds to the bare sclera after pterygium excision. The outcomes were followed for more than one year. Pterygium recurred in 2 (5.3%) of 38 eyes in ethanol group and 4(10.0%) of 40 eyes in MMC group. Final appearance of the pterygium excision area was satisfactory in 73.6% of group1 and 67.5% of group 4. No patients experienced severe complications postoperatively. In comparison with MMC treatment, intraoperative ethanol is more efficacious in preventing recurrence of pterygium and causes fewer complications. It suggests this regimen as an alternative for the treatment of pterygium, especially for those patients of high risk group for MMC treatment complications.
Interleukin-6 Mediates Angiotensinogen Gene Expression during Liver Regeneration
Hong-Shiee Lai, Wen-Hsi Lin, Shuo-Lun Lai, Hao-Yu Lin, Wen-Ming Hsu, Chia-Hung Chou, Po-Huang Lee
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0067868
Abstract: Background Angiotensinogen is the precursor of angiotensin II, which is associated with ischemia-reperfusion injury. Angiotensin II reduces liver regeneration after hepatectomy and causes dysfunction and failure of reduced-size liver transplants. However, the regulation of angiotensinogen during liver regeneration is still unclear. Aims To investigate the regulation of angiotensinogen during liver regeneration for preventing angiotensin II-related ischemia-reperfusion injury during liver regeneration. Methods A mouse in vitro partial hepatectomy animal model was used to evaluate the expression of interleukin-6 (IL-6) and angiotensinogen during liver regeneration. Serum IL-6 and angiotensinogen were detected by enzyme immunoassay (EIA). Angiotensinogen mRNA was detected by RT-PCR. Tissue levels of angiotensinogen protein were detected by Western blot analysis. Primary cultures of mouse hepatocytes were used to investigate IL-6-induced angiotensinogen. Chemical inhibitors were used to perturb signal transduction pathways. Synthetic double-stranded oligodeoxynucleotides (ODNs) were used as ‘decoy’ cis-elements to investigate transcription. Ki 67 staining and quantification were used to verify liver regeneration. Results In the in vivo model, the levels of serum IL-6 and angiotensinogen correlated. In the in vitro model, IL-6 transcriptionally regulated angiotensinogen expression. Additionally, IL-6 mediated angiotensinogen expression through the Janus kinase (JAK)/signal transducer and activator of transcription 3 (STAT3) and JAK/p38 signaling. Decoy ODN analyses revealed that STAT3 and nuclear factor-kB (NF-kB) also played critical roles in the transcriptional regulation of angiotensinogen by IL-6. IL-6-mediated signaling, JAK2, STAT3 and p38 inhibitors reduced angiotensinogen expression in the partially hepatectomized mice. Conclusion During liver regeneration, IL-6-enhanced angiotensinogen expression is dependent on the JAK/STAT3 and JAK/p38/NF-kB signaling pathways. Interruption of the molecular mechanisms of angiotensinogen regulation may be applied as the basis of therapeutic strategies for preventing angiotensin II-related ischemia-reperfusion injury during liver regeneration.
Lysophosphatidic Acid Enhanced the Angiogenic Capability of Human Chondrocytes by Regulating Gi/NF-kB-Dependent Angiogenic Factor Expression
Yi-Wen Chuang, Wen-Ming Chang, Kai-Hua Chen, Chang-Zern Hong, Pey-Jium Chang, Hung-Chih Hsu
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0095180
Abstract: Lysophosphatidic acid (LPA) has been found to mediate myeloid differentiation, stimulate osteogenesis, alter cell proliferation and migration, and inhibit apoptosis in chondrocytes. The effect of LPA on the angiogenic capability of chondrocytes is not clear. This study aimed to investigate its effect on the angiogenic capability of human chondrocytes and the underlying mechanism of these effects. Human chondrocyte cell line, CHON-001, commercialized human chondrocytes (HC) derived from normal human articular cartilage, and human vascular endothelial cells (HUVECs) were used as cell models in this study. The angiogenic capability of chondrocytes was determined by capillary tube formation, monolayer permeability, cell migration, and cell proliferation. An angiogenesis protein array kit was used to evaluate the secretion of angiogenic factors in conditioned medium. Angiogenin, insulin-like growth factor-binding protein 1 (IGFBP-1), interleukin (IL)-8, monocyte chemoattractant protein-1 (MCP-1), matrix metalloproteinase (MMP)-9, and vascular endothelial growth factor (VEGF) mRNA and protein expressions were evaluated by Q-RT-PCR and EIA, respectively. LPA receptor (LPAR) expression was determined by RT-PCR. Signaling pathways were clarified using inhibitors, Western blot analysis, and reporter assays. The LPA treatment promoted the angiogenic capability of CHON-001 cells and HC, resulting in enhanced HUVEC capillary tube formation, monolayer permeability, migration, and cell growth. Angiogenin, IGFBP-1, IL-8, MCP-1, MMP-9, and VEGF mRNA and protein expressions were significantly enhanced in LPA-treated chondrocytes. LPA2, 3, 4 and 6 were expressed in CHON-001 and HC cells. Pretreatment with the Gi/o type G protein inhibitor, pertussis toxin (PTX), and the NF-kB inhibitor, PDTC, significantly inhibited LPA-induced angiogenin, IGFBP-1, IL-8, MCP-1, MMP-9, and VEGF expressions in chondrocytes. The PTX pretreatment also inhibited LPA-mediated NF-kB activation, suggesting the presence of active Gi/NF-kB signaling in CHON-001 and HC cells. The effect of LPA on the angiogenesis-inducing capacity of chondrocytes may be due to the increased angiogenesis factor expression via the Gi/NF-kB signaling pathway.
Applications of minirhizotron techniques to root ecology research

BAI Wen-Ming,

生态学报 , 2005,
Abstract: Plant root plays an important role in anchorage and water and nutrient acquirement.However methodological limitations have troubled many researchers because of the inaccessibility of belowground systems.It appears important to find a good approach for in situ observation of root growth.The minirhizotron method has been regarded as the most promising method for root studies so far.This article aims to introduce the method to researchers in China and to synthesize several issues involved in the application of...


系统科学与数学 , 1996,
Abstract: In this paper, we establish some positive fixed point theorems of cone expansion and compression with norm type for weakly inward set-contraction maps,and also, we get some positive eigenvector results for this map.
A Study of the Isotopic Composition of the Xiaorequanzi Copper and Zinc Deposit in Xinjiang, China

CHEN Wen-ming,

地球学报 , 1999,
Abstract: 小热泉子矿床是我国最近发现的一个中型富铜( 锌) 矿床,其矿床成因为众多的矿床学家所关注。本文对该矿床中不同类型矿石、矿物的S、O、H、Si 及稀有( 惰性) 气体He、Ar 同位素特征作了较祥细的论述,同时用KAr 法对硫化物的年龄测定进行了初步尝试。该矿床硫化物的δ34S 值为+ 1-5 ‰~+ 11-1 ‰,平均为6-15 ‰(46) ;3 He/4 He( 初始) 值为5 ×10 - 8 ~2-17 ×10 - 6 ,平均为0-64 ×10 - 6(6) ,40 Ar/36Ar 值为305-27
Pointwise weighted approximation of functions with inner singularities by combinations of Bernstein operators
Wen-ming Lu,Lin Zhang
Mathematics , 2010,
Abstract: We introduce another new type of combinations of Bernstein operators in this paper, which can be used to approximate the functions with inner singularities. The direct and inverse results of the weighted approximation of this new type combinations are obtained.
Pointwise weighted approximation of functions with endpoint singularities by combinations of Bernstein operators
Wen-ming Lu,Lin Zhang
Mathematics , 2010,
Abstract: We give direct and inverse theorems for the weighted approximation of functions with endpoint singularities by combinations of Bernstein operators.
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