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Search Results: 1 - 10 of 13850 matches for " Weiqiang Fan "
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The Development of Network based Composite Power quality Regulation Device  [PDF]
Weiqiang Fan, Ying Lei, Jing Zhu, Luo Li, Shuai Niu
Energy and Power Engineering (EPE) , 2013, DOI: 10.4236/epe.2013.54B230
Abstract: First, the paper analyzes the advantages and disadvantages of all kinds of reactive power compensation technology, and then proposes a principle and integrated control strategy of the composite operation of TSC and SVG, also the paper designs and develops the main controller of Network based composite power quality regulation device, based on RTDS, the real-time digital simulation model of The Device is established, and finally the prototype of the device is developed with the function of filter and split-phase compensation. The main controller determines the cooperative operation of both TSC and SVG, and the switching strategy of TSC. The simulation result in RTDS can verify the precision of the measure system and the validity of the control logic, the prototype has finished the type test according to the national standard.
In silico Experimentation of Glioma Microenvironment Development and Anti-tumor Therapy
Yu Wu,Yao Lu,Weiqiang Chen,Jianping Fu,Rong Fan
PLOS Computational Biology , 2012, DOI: 10.1371/journal.pcbi.1002355
Abstract: Tumor cells do not develop in isolation, but co-evolve with stromal cells and tumor-associated immune cells in a tumor microenvironment mediated by an array of soluble factors, forming a complex intercellular signaling network. Herein, we report an unbiased, generic model to integrate prior biochemical data and the constructed brain tumor microenvironment in silico as characterized by an intercellular signaling network comprising 5 types of cells, 15 cytokines, and 69 signaling pathways. The results show that glioma develops through three distinct phases: pre-tumor, rapid expansion, and saturation. We designed a microglia depletion therapy and observed significant benefit for virtual patients treated at the early stages but strikingly no therapeutic efficacy at all when therapy was given at a slightly later stage. Cytokine combination therapy exhibits more focused and enhanced therapeutic response even when microglia depletion therapy already fails. It was further revealed that the optimal combination depends on the molecular profile of individual patients, suggesting the need for patient stratification and personalized treatment. These results, obtained solely by observing the in silico dynamics of the glioma microenvironment with no fitting to experimental/clinical data, reflect many characteristics of human glioma development and imply new venues for treating tumors via selective targeting of microenvironmental components.
Quantum Supergroups III. Twistors
Sean Clark,Zhaobing Fan,Yiqiang Li,Weiqiang Wang
Mathematics , 2013, DOI: 10.1007/s00220-014-2071-4
Abstract: We establish direct connections at several levels between quantum groups and supergroups associated to bar-consistent super Cartan datum by constructing an automorphism (called twistor) in the setting of covering quantum groups. The canonical bases of the halves of quantum groups and supergroups are shown to match under the twistor up to powers of a square root of -1. We further show that the modified quantum group and supergroup are isomorphic over the rational function field adjoint with a square root of -1, by constructing a twistor on the modified covering quantum group. An equivalence of categories of weight modules for quantum groups and supergroups follows.
Aflatoxin B1 Negatively Regulates Wnt/β-Catenin Signaling Pathway through Activating miR-33a
Yi Fang, Youjun Feng, Tongjin Wu, Swaminath Srinivas, Weiqiang Yang, Jue Fan, Chi Yang, Shihua Wang
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0073004
Abstract: MicroRNAs are known to play an important role in modulating gene expression in various diseases including cancers and cardiovascular disorders, but only a few of them are associated with the pathology of aflatoxin B1 (AFB1), a potent mycotoxin. Here, we discovered a novel regulatory network between AFB1, miR-33a and β-catenin in human carcinoma cells. The level of miR-33a was up-regulated in hepatocellular carcinoma (HCC) cells treated with AFB1, while in the same cells causing the decrease in β-catenin expression when treated at their IC50 values. miR-33a, specifically miR-33a-5p, was demonstrated to down-regulate the expression of β-catenin, affect the β-catenin pathway, and inhibit cell growth. Also, by employing a luciferase assay, we found that miR-33a down-regulated β-catenin by directly binding to the 3’-UTR of β-catenin. These results suggested that AFB1 might down-regulate β-catenin by up-regulating miR-33a. This understanding opens new lines of thought in the potential role of miR-33a in the clinical therapy of cancer.
Storytelling and Communal Singing: Effective Forms of Appropriation to Destabilize White Supremacy
Weiqiang Mao
Journal of Language Teaching and Research , 2010, DOI: 10.4304/jltr.1.6.871-875
Abstract: Community features importantly both in the assertion of Afro-Americans’ selfhood and the rehabilitation of their culture once lost in slavery. Toni Morrison believes that appropriation in the form of community storytelling and communal singing within black community is an effective instrument to destabilize white supremacy. This paper examines how community storytelling and communal singing works in Morrison’s novel Beloved to rebuild African Americans’ communal solidarity and start a discursive practice of cultural reconstruction.
Give the Screw Another Turn—A Cultural Re-Reading of the Turn of the Screw
Weiqiang Mao
Journal of Language Teaching and Research , 2010, DOI: 10.4304/jltr.1.1.44-49
Abstract: Henry James’ novel The Turn of the Screw is notorious for its ambiguous nature about the ghostly figures that keep haunting the protagonist the governess. This paper attempts to give the study of this novel another turn of the screw by arguing that it is a hybrid of popular culture of ghost stories and high culture of psychological studies of ghosts. It is intended by Henry James as a blueprint for the development of American culture.
Teaching Culture Within and Beyond Language
Weiqiang Mao
English Language Teaching , 2009, DOI: 10.5539/elt.v2n4p144
Abstract: This paper attempts to make a thorough examination of the factors that necessitate and influence the teaching of culture in the EFL classrooms with an aim to present a mode of culture teaching in China.
Equivariant K-theory, wreath products, and Heisenberg algebra
Weiqiang Wang
Physics , 1999,
Abstract: Given a finite group G and a G-space X, we show that a direct sum $F_G (X) = \bigoplus_{n \geq 0}K_{G_n} (X^n) \bigotimes \C$ admits a natural graded Hopf algebra and $\lambda$-ring structure, where $G_n$ denotes the wreath product $G \sim S_n$. $F_G (X)$ is shown to be isomorphic to a certain supersymmetric product in terms of $K_G(X)\bigotimes \C$ as a graded algebra. We further prove that $F_G (X)$ is isomorphic to the Fock space of an infinite dimensional Heisenberg (super)algebra. As one of several applications, we compute the orbifold Euler characteristic $e(X^n, G_n)$.
Double affine Hecke algebras for the spin symmetric group
Weiqiang Wang
Mathematics , 2006,
Abstract: We introduce a new class (in two versions) of rational double affine Hecke algebras (DaHa) associated to the spin symmetric group. We establish the basic properties of the algebras, such as PBW and Dunkl representation, and connections to Nazarov's degenerate affine Hecke-Clifford algebra and to a new degenerate affine Hecke algebra introduced here. We formulate a Morita equivalence between the two versions of rational DaHa's. The trigonometric generalization of the above constructions is also formulated and its relation to the rational counterpart is established.
Nilpotent orbits and finite W-algebras
Weiqiang Wang
Mathematics , 2009,
Abstract: In recent years, the finite W-algebras associated to a semisimple Lie algebra and its nilpotent element have been studied intensively from different viewpoints. In this lecture series, we shall present some basic constructions, connections, and applications of finite W-algebras.
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