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Search Results: 1 - 10 of 14725 matches for " Weimin Jia "
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Effect of GbKTN1 fromGossypium barbadense on cell elongation of fission yeast (Schizosaccharomyces pombe)
Weimin Li,Zhixing Wang,Shirong Jia
Chinese Science Bulletin , 2004, DOI: 10.1007/BF02901738
Abstract: TheGbKTN1 gene was isolated from 10 DPA fiber cells ofGossypium barbadense using 5′RACE/3′RACE. Full-length cDNA of this gene is 2006 bp, including a 113 bp of 5′untranslated region, a 1563 bp of an open reading frame (ORF), and a 327 bp of 3′untranslated region (excluding the stop codon TAA). The ORF ofGbKTN1 encodes a 521-amino acid protein with a predicted size of 55 kD. Near C-terminal of the deduced protein there is a putative ATP binding site between amino acid residues from 233 to 414. Southern blot analysis indicated that theGbKTN1 was a single copy gene inG. barbadense. Combining semi-quantitative RT-PCR with Southern blot hybridization revealed thatGbKTN1 expressed in all the organs detected such as roots, stems, leaves and fibers. However, the mRNA ofGbKTN1 was the most abundant in fiber cells, while it was the lowest in leaves. TheGbKTN1 cDNA was transformed intoS. pombe to verify its function on cell elongation. Results showed that most yeast cells over expressingGbKTN1 gene were elongated dramatically with an average length increase of 2.18 times than that of the non-induced cells. Even the morphology of some yeast cells appeared irregularly. To the best of our knowledge this is the first evidence that KTN1 is correlated with cell elongationin vivo.
Singularity Profile in the Mean Curvature Flow
Weimin Sheng,Xu-Jia Wang
Mathematics , 2009,
Abstract: In this paper we study the geometry of first time singularities of the mean curvature flow. By the curvature pinching estimate of Huisken and Sinestrari, we prove that a mean curvature flow of hypersurfaces in the Euclidean space $\R^{n+1}$ with positive mean curvature is $\kappa$-noncollapsing, and a blow-up sequence converges locally smoothly along a subsequence to a smooth, convex blow-up solution. As a consequence we obtain a local Harnack inequality for the mean convex flow.
A Generalized Tanh-Function Type Method and the(G'/G) -Expansion Method for Solving  [PDF]
Weimin Zhang
Applied Mathematics (AM) , 2013, DOI: 10.4236/am.2013.410A1003
Abstract: In this paper a generalized tanh-function type method is proposed by using the idea of the transformed rational function method. We show that the (G'/G) -expansion method is a special case of the generalized tanh-function type method, so the (G'/G) -expansion method is considered as a special deformation application of the transformed rational function method. We demonstrate that all solutions obtained by the (G'/G) -expansion method were found by the generalized tanh-function type method. As applications, we consider mKdV equation. Compared with the (G'/G) -expansion method, the generalized tanh-function type method gives new and more abundant solutions.
The Analysis of Jackson’s Victory over the Second Bank of the United States  [PDF]
Weimin Liang
Modern Economy (ME) , 2018, DOI: 10.4236/me.2018.96073
Abstract: This article aims to analyze the reasons for the Jackson’s bank war over theSecond Bank of United States. It shows us a new perspective on the reason, which focuses on the different growth backgrounds of Jackson and Biddle. The President Jackson vetoed the bill for the postponement of the Second Bank of United States. And the different personality of Jackson and the Biddle, the president of the Second Bank of United States are important reasons for that. What’s more, the collapse of the Second Bank of United States prevented the financial power from being too concentrated, which did harm to the state power. The Jackson’s victory establishes the fundamental of Federal Reserve system, and gives the wall street spaces to flourish.
Tunable Nanocrystals Fabricated by Free Dealloying of Amorphous Ribbons
Zhifeng Wang,Chunling Qin,Weimin Zhao,Junqing Jia
Journal of Nanomaterials , 2012, DOI: 10.1155/2012/126715
Abstract: This work discovers that Cu2O nanocrystals with controllable structures can be synthesized on surfaces of nanoporous Cu and amorphous ribbons by free dealloying of Cu-based amorphous alloys in acidic solutions. Technological parameters, such as the acid, acid concentration, and dealloying time strongly influence the crystal size, structure and morphology of Cu2O. Cu2O nanocubes are fabricated on surfaces of nanoporous Cu in the hydrofluoric acid treated alloy, while various Cu2O particles are tailored on surfaces of amorphous alloys immersed in hydrochloric acid for different time. The increasing dealloying time and adsorbed oxygen improve the growth rates along the 〈1 0 0〉 direction of Cu2O crystals relative to that of the 〈1 1 1〉 direction, which is the key to change the shapes of Cu2O crystals. The understanding of morphology evolution of Cu2O nanocrystals in this work is helpful in tailoring Cu2O particles with designable shapes and controllable properties in application fields.
Effect of GbKTN1 from Gossypium barbadense on cell elongation of fission yeast (Schizosaccharomyces pombe)
Effect of GbKTN1 from Gossypium barbadense on cell elongation of fission yeast(Schizosaccharomyces pombe)

LI Weimin,WANG Zhixing,JIA Shirong,
LIWeimin
,WAMGZjoxomg,KOASjorpmg

科学通报(英文版) , 2004,
Abstract: The GbKTN1 gene was isolated from 10 DPA fiber cells of Gossypium barbadense using 5'RACE/3'RACE. Full-length cDNA of this gene is 2006 bp, including a 113 bp of 5'untranslated region, a 1563 bp of an open reading frame (ORF), and a 327 bp of 3'untranslated region (excluding the stop codon TAA). The ORF of GbKTN1 encodes a 521-amino acid protein with a predicted size of 55 kD. Near C-terminal of the deduced protein there is a putative ATP binding site between amino acid residues from 233 to 414. Southern blot analysis indicated that the GbKTN1 was a single copy gene in G barbadense. Combining semi-quantitative RT-PCR with Southern blot hybridization revealed that GbKTN1 expressed in all the organs detected such as roots, stems, leaves and fibers. However, the mRNA of GbKTN1 was the most abundant in fiber cells, while it was the lowest in leaves. The GbKTN1 cDNA was transformed into S. pombe to verify its function on cell elongation. Results showed that most yeast cells over expressing GbKTN1 gene were elongated dramatically with an average length increase of 2.18 times than that of the non-induced cells. Even the morphology of some yeast cells appeared irregularly. To the best of our knowledge this is the first evidence that KTN1 is correlated with cell elongation in vivo.
Linear-Combined-Code-Based Unambiguous Code Discriminator Design for Multipath Mitigation in GNSS Receivers
Jiawei Ren,Huihua Chen,Weimin Jia,Minli Yao
Radioengineering , 2012,
Abstract: Unambiguous tracking and multipath mitigation for Binary Offset Carrier (BOC) signals are two important requirements of modern Global Navigation Satellite Systems (GNSS) receivers. A GNSS discriminator design method based on optimization technique is proposed in this paper to meet these requirements. Firstly, the discriminator structure based on a linear-combined code is given. Then the requirements of ideal discriminator function are converted into the mathematical constraints and the objective function to form a non-linear optimization problem. Finally, the problem is solved and the local code is generated according to the results. The theoretical analysis and simulation results indicate that the proposed method can completely remove the false lock points for BOC signals and provide superior multipath mitigation performance compared with traditional discriminator and high revolution correlator (HRC) technique. Moreover, the proposed discriminator is easy to implement for not increasing the number of correlators.
The effect and mechanism of endothelin-1-induced intracellular free calcium in human lung adenocarcinoma cells SPC-A1
Juan ZHOU,Weimin ZHANG,Qianjun YE,Gang JIA
Chinese Journal of Lung Cancer , 2008,
Abstract: Background and objective Endothelin-1 (ET-1) is a potent mitogen involved in cell growth in human lung adenocarcinoma cells SPC-A1. The increase in intracellular free calcium ([Ca2+]i) plays a great role in this process. The aim of this study is to investigate the ET-1-induced [Ca2+]i responses in SPC-A1 cells and to explore its cellular mechanism. Methods [Ca2+]i was measured by Fura-2/AM fluorescent assay. Endothelin receptors antagonists, calcium channel blockers and intracellular signal transduction blockers were used to study the underlying mechanism of ET-1-induced [Ca2+]i responses in SPC-A1 cells. Results At the concentration of 1×10-15 mol/L-1×10-8 mol/L, ET-1 caused a dose-dependent increase of [Ca2+]i in SPC-A1 cells (P<0.05) in vitro. The ET-1-induced (1×10-10 mol/L) increase of [Ca2+]i was blocked by BQ123 at 1×10-7 mol/L (P<0.05), a highly selective endothelin receptor A (ETAR) antagonist, not by BQ788 at 10-7 mol/L (P>0.05), a highly selective endothelin receptor B (ETBR) antagonist. Depletion of extracellular Ca2+ with free Ca2+ solution and 0.1mmol/L ethyleneglycol bis (2-aminoethyl ether) tetraacetic acid (EGTA) or blockade of voltage dependent calcium channel with nifedipine at 1×10-6 mol/L significantly reduced the ET-1-induced increase of [Ca2+]i. The ET-1-induced (1×10-10 mol/L) increase of [Ca2+]i was also significantly attenuated by U73122 at 1×10-5 mol/L (P<0.05), a phospholipase C inhibitor, and by Ryanodine at 50×10-6 mol/L. However, Staurosporine (2×10-9 mol/L), a protein kinas C inhibitor, exerted no significant effect on the ET-1-induced (1×10-10 mol/L) increase of [Ca2+]i. Conclusion ET-1 elevates [Ca2+]i via activation of ETA receptor. Both phospholipase C/Ca2+ pathway and Ca2+ influx through voltage dependent Ca2+ channel activate by ETAR contribute to this process.
Effects of paclitaxel and gefitinib on the proliferation and cell cycle of human lung adenocarcinoma cell SPC-A1
Gang JIA,Weimin ZHANG,Juan ZHOU,Zhixia ZHOU
Chinese Journal of Lung Cancer , 2008,
Abstract: Background and objective Previous clinical trials showed that there was no clinical benefit in the treatment of advanced non-small cell lung cancer when chemotherapy combined with gefitinib. The present study aims to assess the sequential administration of paclitaxel and gefitinib on the cell proliferation of lung adenocarcinoma cell SPC-A1 and to explore its mechanism by observing their effects on the cell cycle. Methods The expression of EGFR mRNA and EGFR protein were examined by RT-PCR and western blotting respectively. MTT was used to measure the cell proliferation of SPC-A1 cells. Cell cycle was detected by flow cytometry. Results Both EGFR mRNA and EGFR protein were overexpressed in SPC-A1 cells. From 1×10-14 M to 1×10-6 M, both paclitaxel and gefitinib inhibited the cell proliferation of SPC-A1 cells in a dose-dependent and time-dependent manner in vitro. The effects of paclitaxel in combination with gefitinib on cell proliferation depended on the sequence. No significant additive effects on cell proliferation was found when they were used simultaneously or gefitinib was added before paclitaxel. However, sequential administration of gefitinib following paclitaxel can remarkably enhanced the effect of paclitaxel on the cell proliferation of SPC-A1 cells. Cell cycle studies showed that paclitaxel and gefitinib induced G2/M and G0/G1 arrest respectively. The G0/G1 arrest was observed when paclitaxel and gefitinib was used simultaneously or gefitinib was added before paclitaxel. In contrast, sequential administration of gefitinib following paclitaxel induced G2/M arrest. Conclusion Both paclitaxel and gefitinib inhibits the cell proliferation of SPC-A1 cells. The additive effects on cell proliferation are sequential-dependent. The concomitant and the sequential treatment of gefitinib followed by paclitaxel exert no significant additive effects on the cell proliferation and resulted in the accumulation of cells in G0/G1 phase, which may decrease the effectiveness of paclitaxel in subsequent cycles. The additive effected on the cell proliferation are observed only when gefitinib is sequentially administrated following paclitaxel, which results in the G2/M arrest. The increase in G2/M phase suggests that cell cycle effects might not explain the observed additive effects.
A Cross-sectional Investigation on Risk Factors of Lung Cancer for Residents over 40 Years Old in Chengdu, Sichuan Province, China
Bojiang CHEN,Weimin LI,Yong JIA,Na GUO
Chinese Journal of Lung Cancer , 2010,
Abstract: Background and objective In the previous studies, we have designed the Self-evaluation Scoring Questionnaire for High-risk Individuals of Lung Cancer. In order to make a better understanding of the status of risk factors of lung cancer for residents in Chengdu, we carried out the investigation from June 2009 to December 2009. Methods With the stratified random sampling method, eligible residents were included and their risk factors of lung cancer were collected with the Self-evaluation Scoring Questionnaire for High-risk Individuals of Lung Cancer. Results According to the criteria of the questionnaire, 21.34% of the population were at high risk of lung cancer. The smoking rate for male was 48.58%, higher than that of 2.65% for female. About 5.39% of male smokers began smoking before 15 years old. The average daily tobacco consumption in the most population was less than 20 pieces, with a duration between 20 to 40 years. However, there were 11.34% of all women suffered from passive smoking, and another 15.30% and 5.86% of residents were exposed to cooking fumes, minerals or asbestos. As for the previous illness history, 0.77%-18.08% of individuals have connective tissue diseases, pulmonary tuberculosis, emphysema and others. Finally, 4.91% of residents endured the long-term mental depression, and 7.24% had a positive family history of tumors. Conclusion The status of risk factors for lung cancer among residents in Chengdu was not optimistic. It should be paid more attention to tobacco control and environmental improvement to improve people's health.
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